Obstructive Sleep Apnea

About the Disease
Apnea, Obstructive Sleep, also known as obstructive sleep apnea syndrome, is related to obesity-hypoventilation syndrome and hypercholesterolemia, familial, 1, and has symptoms including apnea, back pain and cheyne-stokes respiration. An important gene associated with Apnea, Obstructive Sleep is LEP (Leptin), and among its related pathways/superpathways are Metabolism of proteins and Signal Transduction. The drugs Opium and Sorbitol have been mentioned in the context of this disorder. Affiliated tissues include heart, tongue and endothelial, and related phenotypes are anosmia and obstructive sleep apnea

Common Targets
SGCD | LTA | ALDH2 | VDR | Kainate Receptor (GluR) (nonspecified subtype) | G3569 | HMGCR | G4318 | CHRM4 | Voltage-Gated Sodium Channel Complex | FPR3 | MIF-AS1 | Sodium channel (nonspecified subtype) | G7124 | DPP4 | P2RX3 | TLR2 | G7422 | FPR1 | CA12 | CA6 | HCRTR1 | SERPINE1 | ST8SIA6 | S1PR4 | OXT | SLC6A4 | HTR2A | LOC100287329 | ADRB1 | S1PR3 | GIPR | CA7 | CHRM3 | KCNA5 | CA13 | CAV1 | ADRB2 | FASLG | LEPR | HCRTR2 | KCNK3 | APOE | G3576 | CA2 | EDN1 | FPR2 | alpha1-Adrenoceptor (nonspecified subtype) | Muscarinic Acetylcholine Receptor (mAChR) (nonspecified subtype) | 5-Hydroxytryptamine Receptor 2 (5-HT2) (nonspecified subtype) | HTR2C | KCNK9 | TRPM7 | SPHK1 | GPR55 | GLP1R | CCL2 | SLC6A3 | P2RX2 | OXTR | S1PR1 | CRP | ACE | TLR6 | GAD1 | CNR2 | TAAR1 | HRH3 | PPARG | CYBA | Glutamate Receptor Ionotropic AMPA Receptor | PPARA | MTHFR | 5-Hydroxytryptamine Receptor 3 (5-HT3 receptor) (nonspecified subtype) | KCNH2 | CNR1 | P2X2/3 Receptor Complex | Alpha-2 Adrenergic receptors (nonspecified subtype) | SLC6A2

Note: If you'd like to get a target analysis report for Obstructive Sleep Apnea, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Obstructive Sleep Apnea at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Chondromyxoid Fibroma | Alexander Disease | Mevalonate Kinase Deficiency | Cutaneous T-cell Lymphoma | Atrioventricular Septal Defect | Waardenburg Syndrome Type 2 | Cenani-Lenz Syndactyly Syndrome | Niemann-Pick Disease | McLeod Syndrome | Tendinitis | Leukocyte Adhesion Deficiency Type 1 | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Glycogen Storage Disease Type 9 | Irritable Bowel Syndrome | GATA2 Deficiency | Schaaf-Yang Syndrome | Pituitary Stalk Interruption Syndrome | Cyclic Vomiting Syndrome | Loeys-Dietz Syndrome | Carcinoma, Merkel Cell | Anti-NMDA Receptor Encephalitis | Hypertension, Pulmonary | Inborn Errors Of Metabolism | Granular Corneal Dystrophy Type 1 | Familial Cerebral Amyloid Angiopathy | Pemphigus Foliaceus | Primrose Syndrome | Agammaglobulinemia | 3-methylglutaconic Aciduria Type I | Nasodigitoacoustic Syndrome | Congenital Dysfibrinogenemia | Carney-Stratakis Syndrome | 5-oxoprolinase Deficiency | Keloid | Presbycusis | Congenital Hereditary Endothelial Dystrophy Type I | Alopecia | Heart Failure | Neurofibromatosis Type 1 | Leukoencephalopathy, Progressive Multifocal | Angioedema, Acquired | Acanthosis Nigricans | Pearson Syndrome | Encephalopathy, Ethylmalonic | Vascular Cognitive Impairment | Arts Syndrome | Periventricular Leukomalacia | Giant Cell Glioblastoma | Dysplastic Nevus | Hyperparathyroidism, Secondary | D-2-Hydroxyglutaric Aciduria | Neurofibromatosis-Noonan Syndrome | Lymphoma, Primary Cutaneous Anaplastic Large Cell | Anthrax | Endocarditis | Subacute Sclerosing Panencephalitis | Lymphoproliferative Disorders | Lathosterolosis | Schamberg Disease | Autoimmune Disease | GM2-gangliosidosis AB Variant | Carey-Fineman-Ziter Syndrome | Polyneuropathy | Genitopatellar Syndrome | Stroke, Hemorrhagic | N-acetylglutamate Synthase Deficiency | Tricho-hepato-enteric Syndrome | Paget's Disease Of The Breast | Macrophagic Myofasciitis | Malignant Fibrous Histiocytoma | Graft-versus-host Disease | Fibrosis | Van Der Knaap Disease | Norrie Disease | Spinocerebellar Ataxia Type 5 | Spinocerebellar Ataxia Type 23 | Iron Deficiency Anemia | Pseudohypoaldosteronism | CHOPS Syndrome | Ocular Albinism Type 1 | Cantu Syndrome | Adenocarcinoma | Nemaline Myopathy 10 | Giant Axonal Neuropathy | Connective Tissue Disorders | Intracranial Hypertension | Myoclonic Epilepsy With Ragged Red Fibers | Leiomyoma | Bullous Pemphigoid | Hyperkalemic Periodic Paralysis | Lymphoproliferative Disease, X-linked | Familial Advanced Sleep Phase Syndrome | Hypercalcemia | Cousin Syndrome | Cancer, Bladder | Osteogenesis Imperfecta Type I | Ameloblastic Carcinoma | Hypermetropia | Echinococcosis | Esophagitis, Eosinophilic | Acrodysostosis | Mountain Sickness | Krabbe Disease | Lymphopenia | Rolandic Epilepsy | Glycogen Storage Disease Type 1b | Neurocutaneous Syndromes | Mabry Syndrome | Pancreatitis, Chronic | Multifocal Motor Neuropathy | Schizoaffective Disorder | Charcot-Marie-Tooth Disease, Type 2A | Multiple Myeloma | Spastic Paraplegia Type 7 | Leigh Syndrome | Hartnup Disease | Acne | Crouzon Syndrome With Acanthosis Nigricans | Juvenile Xanthogranuloma | Glycogen Storage Disease Type 0 | Acquired Partial Lipodystrophy | Waardenburg Syndrome Type 2E | Epidermolytic Hyperkeratosis | Facioscapulohumeral Muscular Dystrophy | Epicondylitis | Acute Anterior Uveitis | Hartsfield Syndrome | Spondyloepiphyseal Dysplasia Tarda, X-linked | Fundus Albipunctatus | Primary Cutaneous Amyloidosis | Wagner Disease | Contact Dermatitis | Renal Oncocytoma | Holoprosencephaly | Congenital Heart Defects | Systemic Lupus Erythematosus | Tumoral Calcinosis | L-2-Hydroxyglutaric Aciduria | Hydrocephalus, Normal Pressure | Pierre Robin Syndrome | Arthritis | Hyperandrogenemia | Dengue Shock Syndrome | Urolithiasis | Anorexia Nervosa | Martsolf Syndrome | Familial Pheochromocytoma-paraganglioma | Focal Cortical Dysplasia Type 2 | Hyperferritinemia-cataract Syndrome | Trichothiodystrophy | Hypertension, Renal | Craniosynostosis | Spondylocarpotarsal Synostosis Syndrome | Hypophosphatasia | Urethritis | Cataplexy | Stuve-Wiedemann Syndrome | Orotic Aciduria | Esotropia | Ocular Surface Squamous Neoplasia | Coloboma | Tetanus | Mood Disorder | Chordoid Glioma | Teratozoospermia | Congenital Hereditary Endothelial Dystrophy Type II | Evans Syndrome | Gerstmann-Straussler-Scheinker Syndrome | Atopic Dermatitis | Methylmalonic Aciduria And Homocystinuria, CblC Type | Transient Bullous Dermolysis Of The Newborn | Myeloid Leukemia | Pleural Tuberculosis | Analgesia | Familial Hypobetalipoproteinemia | Atelosteogenesis Type 1 | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Thrombotic Microangiopathy | Kabuki Syndrome | Tyrosine Hydroxylase Deficiency | Pituitary Dwarfism | Learning Disability | Hairy Cell Leukemia | Primary Hyperoxaluria | Charcot-Marie-Tooth Disease, Type 6 | Sarcoidosis | Plasma Cell Leukemia | Christianson Syndrome | Bronchiectasis | Hypogammaglobulinemia | Pyruvate Dehydrogenase Deficiency | Granuloma Annulare | Chromosome 17q21.31 Deletion Syndrome | Carpenter Syndrome | Hypertension, Essential | Desbuquois Syndrome | Spinocerebellar Ataxia Type 16 | Cerebrotendinous Xanthomatosis | Angioedema, Hereditary | Farber Disease | 3-methylglutaconic Aciduria | Common Variable Immunodeficiency | Greenberg Dysplasia | Meningococcal Infections | Gigantism | Priapism | Familial Thoracic Aortic Aneurysm | Cardiac Arrest | Scapuloperoneal Spinal Muscular Atrophy | Pelvic Inflammatory Disease | Epidermolytic Ichthyosis, Annular | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Blood Protein Disorders | X-linked Creatine Transporter Deficiency | Hypothyroidism | SAPHO Syndrome | IMAGe Syndrome | Posterior Polar Cataract | Diabetes | Retinopathy Of Prematurity | Restless Legs Syndrome | Currarino Syndrome | Multiple Sclerosis, Chronic Progressive | Knobloch Syndrome | Charcot-Marie-Tooth Disease, Type 1A | Myelitis | Congenital Dyserythropoietic Anemia Type 1 | Corneal Ulcer | Mucolipidosis | Spinal Cord Diseases | Haim-Munk Syndrome | Splenomegaly | Spondylometaphyseal Dysplasia | Myosin Storage Myopathy | Anorchia | Smoldering Myeloma | Distal Myopathy | Carbohydrate Metabolism Disorders | Premenstrual Syndrome | Trachoma | Graves Disease | Vertigo | Necrobiosis Lipoidica | Fahr Disease | Sick Sinus Syndrome 1 | Adrenoleukodystrophy, X-linked | Alpers Syndrome | Pain | Renal Tubular Acidosis | Temporal Lobe Epilepsy | Spina Bifida | WAGR Syndrome | Hypercholesterolemia, Familial | Angioimmunoblastic T-cell Lymphoma | Hereditary Spherocytosis | Japanese Encephalitis | Behavioral Variant Of Frontotemporal Dementia | Coronary Artery Disease | Creatine Deficiency Syndrome Due To AGAT Deficiency | Myocarditis | Saethre-Chotzen Syndrome | Esophagitis | Myotonia | Bartter Syndrome | Hemochromatosis | Duchenne Muscular Dystrophy | Globozoospermia | Early Infantile Epileptic Encephalopathy 4 | Sandhoff Disease | Spondyloperipheral Dysplasia | Heterotaxy | Deafness, Dystonia, And Cerebral Hypomyelination | Wolman Disease | Tularemia | Hepatoblastoma | Primary Biliary Cholangitis | Hepatitis, Alcoholic | Thromboembolism | Frontotemporal Dementia | Niemann-Pick Disease, Type A | Neurotoxicity | Pilomatrix Carcinoma | Prostatitis | Carcinoid Tumor | Spinal Muscular Atrophy | Congenital Aniridia | Porencephaly | Uterine Leiomyoma | Schistosomiasis | 6-pyruvoyl-tetrahydropterin Synthase Deficiency | VACTERL Association | Dysmorphophobia | Trigonocephaly | Schindler Disease | Restrictive Dermopathy | Wiskott-Aldrich Syndrome | Oligoastrocytoma | Gastritis | Twin-to-twin Transfusion Syndrome | Open-angle Glaucoma | Hyper IgE Syndrome | X-linked Acrogigantism | Meier-Gorlin Syndrome | Woodhouse-Sakati Syndrome | Schistosomiasis Mansoni | Wolfram Syndrome | PHARC Syndrome | Pure Autonomic Failure | Postpoliomyelitis Syndrome | Episodic Ataxia Type 1 | Blepharo-cheilo-odontic Syndrome | Glycogen Storage Disease Type 1 | Zygomycosis | Lipid Storage Diseases | Lymphedema | Hoyeraal-Hreidarsson Syndrome | Glomerulonephritis | Chorea | Coffin-Lowry Syndrome | Epidermolysis Bullosa Simplex With Mottled Pigmentation | Combined Pituitary Hormone Deficiency | Smith-Kingsmore Syndrome | Cholera | DOCK8 Immunodeficiency Syndrome | Noonan Syndrome | Chronic Myelomonocytic Leukemia | Poikiloderma With Neutropenia | Spondylocostal Dysostosis | Fabry's Disease | Scabies | Thrombosis | Xeroderma Pigmentosum Variant Type | Trichuriasis | Alazami Syndrome | Progressive External Ophthalmoplegia | Premature Ejaculation | Tylosis With Esophageal Cancer | 3-methylcrotonyl-CoA Carboxylase Deficiency | Exostoses | Paroxysmal Nocturnal Hemoglobinuria | Androgen Insensitivity | Membranous Nephropathy | Hepatitis E | Tyrosinemia | Spasticity | Congenital Muscular Dystrophy | Gingivitis | Schuurs-Hoeijmakers Syndrome | Chronic Enteropathy Associated With SLCO2A1 Gene | Cornelia De Lange Syndrome | Trichotillomania | Ileitis | Spinocerebellar Ataxia Type 31 | Gangliosidosis | Familial Hypertrophic Cardiomyopathy | Autoimmune Hemolytic Anemia | Inflammatory Bowel Disease | Steel Syndrome | Cold Agglutinin Disease | Thin Basement Membrane Disease | Creatine Deficiency Syndrome | Osteogenesis Imperfecta Type V | Muir-Torre Syndrome | Nephrotic Syndrome Type 1 | Sarcoma, Endometrial Stromal | Seminoma | Poirier-Bienvenu Neurodevelopmental Syndrome | Oligodendroglioma | Tietze Syndrome | Infertility, Male | Nestor-Guillermo Progeria Syndrome | Multiple Sclerosis, Primary Progressive | Dominant Optic Atrophy | Language Disorders | Epilepsy | Peripheral Neuropathy | Anterior Segment Dysgenesis | Cryoglobulinemia | Herpes Genitalis | Hemangioma | Neuroblastoma | Optic Nerve Diseases | Cystinosis | Progressive Familial Intrahepatic Cholestasis Type 2 | Congenital Adrenal Hyperplasia | Panuveitis | Early Infantile Epileptic Encephalopathy | Smith-Magenis Syndrome | Donnai-Barrow Syndrome | Familial Exudative Vitreoretinopathy | Myasthenia Gravis | Trimethylaminuria | Pseudohypoparathyroidism Type 1B | Chronic Granulomatous Disease | Erysipelas | Pitt-Hopkins Syndrome | Bietti Crystalline Dystrophy | Epithelioid Hemangioma | Chylothorax, Congenital | Multiple Epiphyseal Dysplasia