Progressive External Ophthalmoplegia

About the Disease
Chronic Progressive External Ophthalmoplegia, also known as progressive external ophthalmoplegia, is related to progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 1 and progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 4, and has symptoms including ophthalmoplegia An important gene associated with Chronic Progressive External Ophthalmoplegia is TWNK (Twinkle MtDNA Helicase), and among its related pathways/superpathways are Metabolism and Organelle biogenesis and maintenance. The drugs 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid and Protective Agents have been mentioned in the context of this disorder. Affiliated tissues include eye, skeletal muscle and heart, and related phenotypes are Strongly decreased CFP-tsO45G cell surface transport and Strongly decreased CFP-tsO45G cell surface transport

Common Targets
TRNS1 | C1QBP | TWNK | RNASEH1 | POLG | TK2 | SPG7 | TRNI | POLG2 | OPA1 | TRNL1 | GMPR | RRM2B | ROBO3 | TRNM | GJB2 | TRNN | Tubulin | TRNP

Note: If you'd like to get a target analysis report for Progressive External Ophthalmoplegia, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Progressive External Ophthalmoplegia at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

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