Osteomyelitis

About the Disease
Osteomyelitis is related to sapho syndrome and chronic recurrent multifocal osteomyelitis, and has symptoms including pain in limb and bone pain. An important gene associated with Osteomyelitis is LPIN2 (Lipin 2), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Clonidine and Cefazolin have been mentioned in the context of this disorder. Affiliated tissues include bone, bone marrow and spinal cord, and related phenotypes are no effect and no effect

Common Targets
TRPV1 | Hedgehog Protein (nonspecified subtype) | ANO5 | TNFSF11 | PTCH1 | SERPINE1 | IL1B | CTSG | IL1R1 | CEACAM8 | PYCARD | IFNG | NF-kappaB (NFkB) | MEFV | G114548 | MSR1 | CRP | MMP1 | ENOX2 | IL1RN | SMO

Note: If you'd like to get a target analysis report for Osteomyelitis, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Osteomyelitis at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Plasma Cell Dyscrasia | Meningioma, Benign | Carcinoma, Squamous Cell | Macrodactyly | Dystonia | GM2-gangliosidosis AB Variant | Multiple Epiphyseal Dysplasia | Persistent Truncus Arteriosus | Patent Ductus Arteriosus | Inflammatory Bowel Disease | Rickets | Meleda Disease | Sialoadenitis | Amyloidosis | Smith-Kingsmore Syndrome | Cholera | Chordoid Glioma | Dentinogenesis Imperfecta | Primrose Syndrome | Intestinal Tuberculosis | Prurigo Nodularis | Gastroenteritis | Chronic Periodontitis | Aldosteronism | Adrenal Insufficiency | Cholelithiasis | Nestor-Guillermo Progeria Syndrome | Light Chain Amyloidosis | Frontotemporal Dementia | Gastroschisis | GNE Myopathy | Liver Failure, Acute Infantile | Carbamoyl Phosphate Synthetase I Deficiency | Urolithiasis | Ebstein Anomaly | Neuroleptic Malignant Syndrome | Ectodermal Dysplasia | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Leukodystrophies | Vitamin D Deficiency | Huntington's Disease-like 2 | Spinocerebellar Ataxia Type 21 | Glucagonoma | Myasthenia | Long QT Syndrome Type 2 | Infantile Refsum Disease | Binge Eating Disorder | Mitochondrial DNA Depletion Syndrome 13 | Cranioectodermal Dysplasia | Carotid Artery Disease | Spinocerebellar Ataxia Type 13 | Gaucher Disease | Keratosis | Hyperuricemia | Granular Corneal Dystrophy Type 1 | Neuromyotonia | Focal Dermal Hypoplasia | Idiopathic Pulmonary Fibrosis | Saethre-Chotzen Syndrome | Ganglioglioma | Beckwith-Wiedemann Syndrome | Carcinoid Syndrome | Ligneous Conjunctivitis | Metabolic Diseases | C3 Glomerulonephritis | Nephrotic Syndrome | Aicardi-Goutieres Syndrome | Dwarfism | Sarcoma, Ewing | Primary Hyperoxaluria Type 1 | Vaginitis | Hennekam Lymphangiectasia-lymphedema Syndrome | Williams Syndrome | Cholestasis, Intrahepatic | Odonto-onycho-dermal Dysplasia | Epidermolysis Bullosa Simplex With Mottled Pigmentation | Mitochondrial Myopathy | Vertebrobasilar Insufficiency | Gangliosidosis | Hypertension, Essential | Autosomal Recessive Spastic Paraplegia Type 35 | DNA Ligase IV Deficiency | Bloom Syndrome | Currarino Syndrome | Sialidosis | Amblyopia | Hereditary Sensory Neuropathy Type 1 | Saul-Wilson Syndrome | Antithrombin III Deficiency | Epidermal Nevus Syndrome | Anorectal Malformations | Hypercholesterolemia, Familial | Paraganglioma | Pulmonary Alveolar Proteinosis | Nance-Horan Syndrome | Inflammatory Joint Disease | Congenital Absence Of Vas Deferens | Lymphoproliferative Disease, X-linked | Neurofibroma | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Focal Cortical Dysplasia Type 2 | Charcot-Marie-Tooth Disease, Type 2C | Epidermodysplasia Verruciformis | Hypoglycemia | Prediabetes | Gynecomastia | Liver Failure | Nevus | Autism | 3-methylglutaconic Aciduria Type I | Pyruvate Dehydrogenase Deficiency | Venous Insufficiency | Hemorrhoids | Perivascular Epithelioid Cell Tumor | Corneal Dystrophy | Tularemia | Roberts Syndrome | Polycystic Liver | Behavioral Variant Of Frontotemporal Dementia | Ocular Surface Squamous Neoplasia | Trichothiodystrophy | Ophthalmia, Sympathetic | Schamberg Disease | Mucolipidosis Type II | Behcet's Disease | Aarskog-Scott Syndrome | Lennox-Gastaut Syndrome | Hypopigmentation | Osteosclerosis | Sertoli Cell-only Syndrome | VEXAS Syndrome | Hereditary Spastic Paraplegia | Cutaneous Lupus Erythematosus | Dengue Shock Syndrome | Malignant Peripheral Nerve Sheath Tumor | Lichen Sclerosus | Coloboma | Nanophthalmos | Macular Corneal Dystrophy | Ovarian Hyperstimulation Syndrome | HELLP Syndrome | Loeys-Dietz Syndrome | Peutz-Jeghers Syndrome | Stickler Syndrome | Galactosialidosis | Methemoglobinemia Type IV | Transcobalamin Deficiency | Sensorineural Hearing Loss | Primary Hyperoxaluria | Spinocerebellar Ataxia Type 40 | Loeys-Dietz Syndrome Type 4 | Central Retinal Artery Occlusion | Onchocerciasis | Hemoglobinopathies | Ectrodactyly | Urofacial Syndrome | Bardet-Biedl Syndrome | Hydrocephalus | Ehlers-Danlos Syndrome With Progressive Kyphoscoliosis, Myopathy, And Hearing Loss | Carcinoma, Small Cell | Fuchs Dystrophy | Infantile Spasm | Leukocyte Adhesion Deficiency | Succinic Semialdehyde Dehydrogenase Deficiency | Pleural Tuberculosis | Phosphoglycerate Dehydrogenase Deficiency | Pelvic Inflammatory Disease | Posterior Polar Cataract | Cholesteryl Ester Storage Disease | Otosclerosis | Still Disease | Charcot-Marie-Tooth Disease Type 4E | Endophthalmitis | Mixed Connective Tissue Disease | Strabismus | Takenouchi-Kosaki Syndrome | Steel Syndrome | Endometrial Hyperplasia | Stroke, Hemorrhagic | Spondyloepiphyseal Dysplasia Tarda, X-linked | Shprintzen-Goldberg Syndrome | Multicentric Carpotarsal Osteolysis Syndrome | Congenital Disorders Of Glycosylation Type II | Esophageal Motility Disorders | Pyoderma Gangrenosum | Goiter | Addison Disease | Hepatic Veno-occlusive Disease | Arts Syndrome | Tuberculous Meningitis | Waardenburg Syndrome Type 2 | Pseudoexfoliation Syndrome | Orotic Aciduria | Leishmaniasis, Cutaneous | Pituitary Stalk Interruption Syndrome | Mycosis Fungoides | Spondylocostal Dysostosis | Bartsocas-Papas Syndrome | Cockayne Syndrome | Alpers Syndrome | Familial Mediterranean Fever | Cerebellar Ataxia, Cayman Type | Keratocystic Odontogenic Tumor | Fascioliasis | Thrombocythemia, Essential | Pulmonary Tuberculosis | Cholangitis | Uveitis, Anterior | Trimethylaminuria | Splenomegaly | Coronary Artery Disease | Proctitis | Nicolaides-Baraitser Syndrome | Rhinitis | Trichomegaly | Achondrogenesis | Chromosome 17q21.31 Deletion Syndrome | Pneumonia, Bacterial | Sandhoff Disease | Chondrodysplasia Punctata | Anterior Segment Dysgenesis | Tietze Syndrome | Rhabdomyosarcoma, Embryonal | Agammaglobulinemia | Diabetes Type 2 | Melanoma, Uveal | Tyrosine Hydroxylase Deficiency | Renal Hypouricemia | Lissencephaly 2 | Lymphoma, Mantle Cell | Gangliosidosis, GM1 | Fibrosis | Gitelman Syndrome | Distal Myopathy 2 | Spastic Paraplegia Type 7 | Hepatitis, Autoimmune | Waardenburg Syndrome | Heroin Dependence | Malignant Fibrous Histiocytoma | Glaucomatocyclitic Crisis | Familial Isolated Hyperparathyroidism | Hidradenitis Suppurativa | Aceruloplasminemia | Pheochromocytoma | Progressive Familial Intrahepatic Cholestasis Type 2 | Pierre Robin Syndrome | Early Infantile Epileptic Encephalopathy 1 | Autism Spectrum Disorders | Chronic Mucocutaneous Candidiasis | Large Granular Lymphocytic Leukemia | Angiosarcoma | Low Tension Glaucoma | Hyperammonemia | Persistent Mullerian Duct Syndrome | Discoid Lupus Erythematosus | Premenstrual Syndrome | Viral Meningitis | Neuroblastoma | Blepharo-cheilo-odontic Syndrome | Temtamy Preaxial Brachydactyly Syndrome | Gray Platelet Syndrome | 17-beta-hydroxysteroid Dehydrogenase X Deficiency | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Osteogenesis Imperfecta | Primary Torsion Dystonia | Spinocerebellar Ataxia Type 27 | Fanconi Anemia | Leber Congenital Amaurosis | Ileitis | Krabbe Disease | Gnathodiaphyseal Dysplasia | Urticaria | Multicystic Renal Dysplasia | Pancytopenia | Adenoma, Pituitary | Bone Giant Cell Tumor | Psoriasis | Pancreatitis | Hypertension, Pulmonary | Non-bullous Congenital Ichthyosiform Erythroderma | Bronchitis, Chronic | Hartsfield Syndrome | Familial Cerebral Amyloid Angiopathy | Pain | DOCK8 Immunodeficiency Syndrome | Duane Retraction Syndrome | Neutropenia | Peyronie's Disease | Chronic Lymphocytic Leukemia | Herpes Genitalis | Glycogen Storage Disease Type 5 | Palmoplantar Keratoderma | Borderline Personality Disorder | Aldosterone Synthase Deficiency | Alagille Syndrome | Hereditary Folate Malabsorption | Multiple Sclerosis, Chronic Progressive | Episodic Ataxia Type 2 | Exostoses | Syndactyly | Cardiac Arrest | DEND Syndrome | Paracoccidioidomycosis | Amelogenesis Imperfecta | X-linked Myotubular Myopathy | Hypertension | Spinocerebellar Ataxia Type 10 | Congenital Hemolytic Anemia | Lamellar Ichthyosis | Asplenia | Hemophilia | Hermansky-Pudlak Syndrome | Dystonia-parkinsonism, X-linked | Lymphomatoid Granulomatosis | Hypolipoproteinemia | Raine Syndrome | Overactive Bladder | Crouzon Syndrome With Acanthosis Nigricans | Multiple Sclerosis | Canavan Disease | Sturge-Weber Syndrome | Alopecia Areata | Paroxysmal Nocturnal Hemoglobinuria | Aromatic L-amino Acid Decarboxylase Deficiency | Xeroderma Pigmentosum | Gestational Trophoblastic Disease | Mucormycosis | Generalized Epilepsy With Febrile Seizures Plus | Wiedemann-Steiner Syndrome | Cousin Syndrome | Juvenile Xanthogranuloma | Thalassemia | Knobloch Syndrome | Spondylo-ocular Syndrome | Congenital Bilateral Absence Of Vas Deferens | Bulimia Nervosa | Hepatoblastoma | Alpha-1 Antitrypsin Deficiency | 3-M Syndrome | Pemphigus | Myoclonus-dystonia Syndrome | Common Variable Immunodeficiency | Mitochondrial Encephalomyopathy | Cabezas Syndrome | Sarcoidosis | Sarcomatoid Carcinoma Of The Lung | Choroiditis | Antiphospholipid Syndrome | Tinea Versicolor | Lymphangiomatosis | Jawad Syndrome | Miyoshi Myopathy | 3-hydroxy-3-methylglutaryl-CoA Synthase Deficiency | Congenital Bile Acid Synthesis Defect | Spina Bifida | Lipoma | Neural Tube Defect | Familial Thoracic Aortic Aneurysm | Systemic Lupus Erythematosus | Gastritis | Bursitis | Arthritis | Mitochondrial DNA Depletion Syndrome, Myopathic Form | Encephalitis, Tick-borne | Chudley-McCullough Syndrome | Okihiro Syndrome | Hypotrichosis Simplex | Polyomavirus Nephropathy | Centronuclear Myopathy | Primary Erythromelalgia | Neutrophilia | Neurofibromatosis Type 2 | Androgen Insensitivity | Macular Degeneration | Kindler Syndrome | Adams-Oliver Syndrome | Connective Tissue Disorders | Chondroma | Vitelliform Macular Dystrophy | Heimler Syndrome | Pineoblastoma | Hepatitis B, Chronic | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Familial Dysautonomia | Facioscapulohumeral Muscular Dystrophy | Fibromuscular Dysplasia | Hamartoma | Hypotonia-cystinuria Syndrome | Chorea-acanthocytosis | Cardiac Sarcoidosis | Cyclic Vomiting Syndrome | Hereditary Pyropoikilocytosis | Osteoglophonic Dysplasia | Primary Carnitine Deficiency | Werner's Syndrome | Malonyl-CoA Decarboxylase Deficiency | CHARGE Syndrome | Diabetes Insipidus, Nephrogenic | Crigler-Najjar Syndrome | Wilson's Disease