Uveal Melanoma

About the Disease
Melanoma, Uveal, also known as uveal melanoma, is related to ocular melanoma and melanoma. An important gene associated with Melanoma, Uveal is BAP1 (BRCA1 Associated Protein 1), and among its related pathways/superpathways are ADORA2B mediated anti-inflammatory cytokines production and Development Angiotensin activation of ERK. The drugs Triamcinolone and Hormones have been mentioned in the context of this disorder. Affiliated tissues include eye, liver and brain, and related phenotypes are visual loss and choroidal melanoma

Common Targets
EIF1AX | G2099 | PIK3CD | BRD4 | SESN1 | HDAC1 | TYR | MAP2K1 | IDH1 | PRKCA | AURKB | SMARCA2 | Tubulin | G999 | FLT4 | FLT1 | ZNF358 | C-X-C Chemokine Receptor CXCR1/CXCR2 (IL-8 Receptor) (nonspecified subtype) | G4233 | GPNMB | HDAC3 | KDR | ENG | CSPG4 | BTNL2 | ARG1 | SF3B1 | GNAQ | CD40 | NTRK3 | EML4 | NTRK1 | ROS1 | DTWD1 | G3480 | G836 | G5595 | SMARCA4 | FLT3 | Mitogen-Activated Protein Kinase (nonspecified subtype) | RET | CTLA4 | G7015 | PMEL | RAF1 | NFIA | TLR9 | PRKCD | PTK2B | JAK2 | G7157 | G5747 | G672 | NCL | PRKCB | MAP2K2 | KIT | G673 | CLPTM1L | KDM6B | KAT6B | SAMMSON | TIGIT | ENTPD5 | LMCD1-AS1 | MAGEC2 | PBRM1 | CYSLTR2 | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | PRKCQ | G5133 | G238 | NAPRT | CHEK2 | PRLR | RASSF1 | FBXW7 | BAP1 | FAM227B | G1029 | PRKCE | KDM4B | NTRK2 | MBD4 | CCNG2 | HDAC6 | TNFRSF9 | GNA11 | CSF1R | HDAC2 | MC1R | GPER1 | ENPP2 | PDGFRB | SENP6 | G4089 | APEH | MST1R | BRCA2 | CD3 Complex (T Cell Receptor Complex) | PDE4B | KAT2B | PRAME | LMCD1 | RNF2 | PLCB4

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