Corneal Neovascularization

About the Disease
Corneal Neovascularization, also known as extensive superficial corneal vascularisation, is related to keratitis, hereditary and corneal disease. An important gene associated with Corneal Neovascularization is VEGFA (Vascular Endothelial Growth Factor A), and among its related pathways/superpathways are Apoptotic Pathways in Synovial Fibroblasts and ERK Signaling. The drugs Bevacizumab and Pharmaceutical Solutions have been mentioned in the context of this disorder. Affiliated tissues include eye, endothelial and bone marrow, and related phenotypes are homeostasis/metabolism and nervous system

Common Targets
LGALS3 | G7852 | Interleukin-1 (nonspecified subtype) | KDR | CFD | T-Type Calcium Channel | IL-1 Receptor (nonspecified subtype) | G7422 | Fibroblast growth factor (FGF) (nonspecified subtype) | Integrin alphavbeta5 receptor | FGL2 | Integrin alpha5beta1 (VLA-5) receptor | TRAP1 | SCG3 | TRPA1 | Complement Complex | TGFB1 | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | CYSLTR2 | HPSE | CD160 | Integrin alphavbeta1 | Rho kinase (ROCK) (nonspecified subtype) | HIF1A | PDGFRB | RHOA | IRS1 | AOC3 | G2475 | IL1RN | PIK3CA | Integrin alphavbeta3 (vitronectin) receptor | TOP1 | LRP6 | Tyrosine-Protein Kinases Src (nonspecified subtype) | CYSLTR1 | TRPV1

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