Multicentric Carpotarsal Osteolysis Syndrome

About the Disease
Multicentric Carpotarsal Osteolysis Syndrome, also known as multicentric carpo-tarsal osteolysis with or without nephropathy, is related to arthropathy and fibrosarcoma, and has symptoms including wrist pain and ankle pain. An important gene associated with Multicentric Carpotarsal Osteolysis Syndrome is MAFB (MAF BZIP Transcription Factor B), and among its related pathways/superpathways are Vitamin D receptor pathway and Interleukin-11 signaling pathway. Affiliated tissues include bone, kidney and ovary, and related phenotypes are gait disturbance and proteinuria

Common Targets
MAFB

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