Congenital Nephrotic Syndrome

About the Disease
Familial Nephrotic Syndrome, also known as congenital nephrotic syndrome, is related to nephrotic syndrome, type 2 and nephrotic syndrome, type 21, and has symptoms including edema An important gene associated with Familial Nephrotic Syndrome is NPHS1 (NPHS1 Adhesion Molecule, Nephrin), and among its related pathways/superpathways are Cell junction organization and Primary focal segmental glomerulosclerosis (FSGS). Affiliated tissues include Kidney, placenta and brain, and related phenotypes are no effect and no effect

Common Targets
NPHS2 | LAMB2 | CD2AP | EHMT1 | ITGA3 | ARHGDIA | ACTN4 | PLCE1 | WT1 | BSN | TBC1D8B | TLN1 | COQ2 | MAGI2 | SGPL1 | NPHS1

Note: If you'd like to get a target analysis report for Congenital Nephrotic Syndrome, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Congenital Nephrotic Syndrome at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Intestinal Hypomagnesemia 1 | 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Erectile Dysfunction | TARP Syndrome | Hyperferritinemia-cataract Syndrome | Hepatic Veno-occlusive Disease | Wolcott-Rallison Syndrome | Sarcoidosis | Cardiac Sarcoidosis | Intestinal Tuberculosis | Pericarditis | KBG Syndrome | Asthma, Nocturnal | Microphthalmia, Syndromic 7 | Agranulocytosis | Sandhoff Disease | Megaloblastic Anemia | Adrenomyeloneuropathy | Borjeson-Forssman-Lehmann Syndrome | Cherubism | Spinocerebellar Ataxia Type 21 | Acrodermatitis Enteropathica | Allan-Herndon-Dudley Syndrome | Erythropoietic Protoporphyria | Urofacial Syndrome | Spinocerebellar Ataxia Type 3 | Dystrophy, Cone-rod | Infectious Diarrhea | Antithrombin III Deficiency | Congestive Heart Failure | Familial Male-limited Precocious Puberty | Hemoglobinopathies | Endophthalmitis | Ganglioglioma | Polyomavirus Nephropathy | Crouzon Syndrome With Acanthosis Nigricans | Waardenburg Syndrome | Hypereosinophilic Syndrome | Scabies | Temtamy Preaxial Brachydactyly Syndrome | Cardiospondylocarpofacial Syndrome | Marinesco-Sjogren Syndrome | Pneumothorax | Anti-glomerular Basement Membrane Disease | Diamond-Blackfan Anemia | Bronchitis | Erythema Multiforme | Sepiapterin Reductase Deficiency | Gangliosidosis | Blepharoconjunctivitis | Myelomeningocele | Coma | Endocarditis | HIBCH Deficiency | Stromal Corneal Dystrophy | Progressive Familial Intrahepatic Cholestasis Type 1 | Acute Leukemia | Androgen Insensitivity | Guillain-Barre Syndrome | Congenital Nephrotic Syndrome | Progressive Osseous Heteroplasia | Fraser Syndrome | Sarcoma | Myoclonus-dystonia Syndrome | Sporadic Inclusion Body Myositis | Pure Red Cell Aplasia | Viral Meningitis | Prune Belly Syndrome | Ectrodactyly | DOCK8 Immunodeficiency Syndrome | Filariasis | Mucormycosis | Juvenile Myelomonocytic Leukemia | Muscular Dystrophy | Polymicrogyria | Esophagitis | Encephalopathy, Ethylmalonic | Cardiomyopathy, Peripartum | Acne Vulgaris | Behavioral Variant Of Frontotemporal Dementia | Dysferlinopathy | Pyruvate Decarboxylase Deficiency | Intracranial Hypertension | Dyslexia | Batten Disease | Gastroenteritis, Eosinophilic | Iron Deficiency Anemia | Osteogenesis Imperfecta Type IV | Prurigo Nodularis | Basal Ganglia Cerebrovascular Disease | Hereditary Spastic Paraplegia | Cholestasis | Hyperinsulinism-hyperammonemia Syndrome | 3-hydroxy-3-methylglutaryl-CoA Synthase Deficiency | Chondromyxoid Fibroma | Goiter, Nodular | Vertigo | Gastrointestinal Disorders | Chorioretinitis | Stickler Syndrome | Congenital Afibrinogenemia | Tuberculosis | Hypodontia | Presbyopia | Iron Overload | Brenner Tumor | Pituitary Dwarfism | Cockayne Syndrome | Hepatitis B, Chronic | Neurodevelopmental Disorders | Myelitis, Transverse | Neurocutaneous Syndromes | Keratosis, Actinic | Bone Giant Cell Tumor | Epidermolysis Bullosa Dystrophica | IMAGe Syndrome | Hemolytic Uremic Syndrome, Atypical | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Chronic Enteropathy Associated With SLCO2A1 Gene | Congenital Dyserythropoietic Anemia | Retinal Dystrophy, Early-onset Severe | Empyema | Tenosynovial Giant Cell Tumor | Coffin-Lowry Syndrome | X-linked Creatine Transporter Deficiency | Dystonia-parkinsonism, X-linked | Smith-Kingsmore Syndrome | Carcinoma, Small Cell | Greenberg Dysplasia | Pernicious Anemia | Autoimmune Hemolytic Anemia | Familial Hemiplegic Migraine | Congenital Disorders Of Glycosylation | Kashin-Beck Disease | Prolactinoma | Familial Retinal Arterial Macroaneurysm | Wagner Disease | Thrombophilia | Spinocerebellar Ataxia Type 17 | Persistent Hyperplastic Primary Vitreous | Guanidinoacetate Methyltransferase Deficiency | Achromatopsia | Chronic Idiopathic Myelofibrosis | Inflammatory Joint Disease | Lipid Storage Diseases | Communication Disorders | Glioblastoma Multiforme | Shwachman-Bodian-Diamond Syndrome | Antley-Bixler Syndrome | Epidermolysis Bullosa Simplex | Dysplastic Nevus | Polycythemia Vera | Leukemia | Tularemia | Keratopathy | Non-small Cell Lung Cancer | Gangliosidosis, GM1 | Dystonia Musculorum Deformans | Galactosemia | Giant Cell Arteritis | Herpes Genitalis | SAPHO Syndrome | Progressive Myoclonic Epilepsy | Pearson Syndrome | Haim-Munk Syndrome | Congenital Nystagmus | Albinism | Lymphoma | Thromboembolism | Infantile Refsum Disease | Robinow Syndrome | Vasculitis | Sclerocornea | Creutzfeldt-Jakob Disease | Plasmacytoma | Congenital Disorders Of Glycosylation Type II | Sleep Apnea, Central | VEXAS Syndrome | Hypopituitarism | Adenoma, Pleomorphic | Pierre Robin Syndrome | Myoclonic Epilepsy With Ragged Red Fibers | Scleritis | Cerebral Amyloid Angiopathy | Metachromatic Leukodystrophy | Sorsby Fundus Dystrophy | Melanoma, Uveal | Aphasia | Chromosome 17q21.31 Deletion Syndrome | Adenosine Deaminase 2 Deficiency | Gigantism | Trichomegaly | Epiphyseal Chondrodysplasia, Miura Type | Osteomalacia | Connective Tissue Disorders | Retinitis Pigmentosa 3 | Congenital Dyserythropoietic Anemia Type 1 | Triphalangeal Thumb-polysyndactyly Syndrome | Guttate Psoriasis | Thyroiditis | Beckwith-Wiedemann Syndrome | Spasticity | Hyperkeratosis | Spondylo-ocular Syndrome | Li-Fraumeni Syndrome | Sjogren Syndrome | Parapsoriasis | Polymyalgia Rheumatica | Orthostatic Intolerance | Gynecomastia | Angioedema | Chronic Kidney Disease | Adult Polyglucosan Body Disease | HANAC Syndrome | Rash | Lamellar Ichthyosis | Diabetes Mellitus, Transient Neonatal | Cranioectodermal Dysplasia | Schnyder Crystalline Corneal Dystrophy | Gastric Atrophy | Muir-Torre Syndrome | Turner's Syndrome | Focal Facial Dermal Dysplasia | Atopy | Histiocytosis | Neurofibroma | Lymphangioma | Thanatophoric Dysplasia | Keratoconjunctivitis | 3C Syndrome | Leigh Syndrome | Compartment Syndrome | Osteogenesis Imperfecta Type II | Benign Hereditary Chorea | Alkaptonuria | Pneumonia, Bacterial | Oligodendroglioma | Chronic Mucocutaneous Candidiasis | Triple A Syndrome | Reye Syndrome | Trichotillomania | Budd-Chiari Syndrome | Maple Syrup Urine Disease | Pyruvate Kinase Deficiency | Hyperphenylalaninemia | Keratosis, Seborrheic | Chronic Inflammatory Demyelinating Polyneuropathy | Usher Syndrome Type III | Hyper IgE Syndrome | Aceruloplasminemia | Congenital Torticollis | Angelman Syndrome | Seasonal Mood Disorder | Oculocutaneous Albinism Type 4 | Irritable Bowel Syndrome | Hyperinsulinemic Hypoglycemia | Ichthyosis Bullosa Of Siemens | Diarrhea | Hypercalcemia | Cholestasis, Intrahepatic | Optic Neuropathy | Pelvic Inflammatory Disease | Charcot-Marie-Tooth Disease | Lipid Storage Myopathy | Emery-Dreifuss Muscular Dystrophy | Lymphoproliferative Disorders | Toxic Epidermal Necrolysis | Meningitis | Charcot-Marie-Tooth Disease Type 2E | Pierson Syndrome | T-cell Lymphoma, Subcutaneous Panniculitis-like | Glutaric Aciduria Type 2 | Renal Tubular Acidosis | Cardiomyopathy, Restrictive | Cushing Syndrome | Brachial Plexus Neuropathy | Fatty Aldehyde Dehydrogenase Deficiency | Leukocyte Adhesion Deficiency | Carbamoyl Phosphate Synthetase I Deficiency | Pulverulent Zonular Cataract | DNA Ligase IV Deficiency | Corneal Edema | Lewy Body Dementia | Toxoplasmosis | Pseudoexfoliation Syndrome | Ataxia-ocular Apraxia 2 | Tendinopathy | Dubin-Johnson Syndrome | Tardive Dyskinesia | Vitelliform Macular Dystrophy | Combined Malonic And Methylmalonic Acidemia | Pseudohypoparathyroidism Type 1A | Plasma Cell Leukemia | Sarcoma, Ewing | Congenital Adrenal Hyperplasia 1 | Bardet-Biedl Syndrome | Acute Generalized Exanthematous Pustulosis | Adenomyosis | Basan Syndrome | Bronchiolitis | Nestor-Guillermo Progeria Syndrome | Primary Lateral Sclerosis | Familial Advanced Sleep Phase Syndrome | Colitis, Lymphocytic | Enlarged Vestibular Aqueduct | Dyslipidemia | Early Infantile Epileptic Encephalopathy 28 | Hemangioendothelioma | Carbohydrate Metabolism Disorders | Poirier-Bienvenu Neurodevelopmental Syndrome | Juvenile Polyposis | Krabbe Disease | Spinal Muscular Atrophy Type 3 | Zellweger Syndrome | Retinal Vasculitis | Diabetic Nephropathy | Otosclerosis | Genitopatellar Syndrome | POEMS Syndrome | Optic Neuropathy, Anterior Ischemic | Stomatitis | Phenylketonuria | Meningococcal Meningitis | Lupus Erythematosus | Absence Epilepsy | Eclampsia | Ventricular Septal Defect | Non-epidermolytic Palmoplantar Keratoderma | Gnathodiaphyseal Dysplasia | Methylmalonic Aciduria And Homocystinuria, CblC Type | Analgesia | Vaginitis | Heterotopic Ossification | Spinal Muscular Atrophy | Choroideremia | Fukuyama Congenital Muscular Dystrophy | Kohlschutter-Tonz Syndrome | Thrombosis | Osteoporosis-pseudoglioma Syndrome | Pendred Syndrome | Spinocerebellar Ataxia Type 7 | Porphyria | Asperger Syndrome | Glycogen Storage Disease Type 1a | Babesiosis | Globozoospermia | Chorea | Phenylketonuria II | Charcot-Marie-Tooth Disease Axonal Type 2N | Hepatopulmonary Syndrome | Retinitis Pigmentosa | Galloway-Mowat Syndrome | Tendinitis | Myotonic Disorders | Diabetes Insipidus | Cirrhosis | Meckel-Gruber Syndrome | Arthrogryposis | Bloom Syndrome | Nemaline Myopathy 10 | Macular Corneal Dystrophy Type 1 | Nail Disorder, Nonsyndromic Congenital | Chordoma | Wolman Disease | Ameloblastoma | Amyotrophic Lateral Sclerosis | PASLI Disease | 17-beta-hydroxysteroid Dehydrogenase X Deficiency | Oculocutaneous Albinism Type 1 | Angiodysplasia | Panniculitis | Papulopustular Rosacea | Neonatal Progeroid Syndrome | Pregnancy, Ectopic | Non-proliferative Diabetic Retinopathy | Danon Disease | Adams-Oliver Syndrome | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Hypertension, Pulmonary | Takayasu's Arteritis | Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form | Juvenile Myoclonic Epilepsy | Polyneuropathy | Schaaf-Yang Syndrome | Leishmaniasis, Visceral | Borderline Personality Disorder | Ocular Hypertension | Heroin Dependence | Congenital Sodium Diarrhea | Brugada Syndrome 1 | Rickets | Uterine Leiomyoma | Congenital Dysfibrinogenemia | Waardenburg Syndrome Type 4A | Angioimmunoblastic T-cell Lymphoma | Primary Carnitine Deficiency | Farber Disease | Azoospermia | Aplastic Anemia | Rheumatic Heart Disease