Autosomal Recessive Spastic Paraplegia Type 75

About the Disease
Spastic Paraplegia 75, Autosomal Recessive, also known as hereditary spastic paraplegia 75, is related to balo concentric sclerosis and central pontine myelinolysis. An important gene associated with Spastic Paraplegia 75, Autosomal Recessive is MAG (Myelin Associated Glycoprotein), and among its related pathways/superpathways are "Oligodendrocyte specification and differentiation, leading to myelin components for CNS" and Glial cell differentiation. Affiliated tissues include brain, and related phenotypes are intellectual disability and global developmental delay

Common Targets
MAG

Note: If you'd like to get a target analysis report for Autosomal Recessive Spastic Paraplegia Type 75, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Autosomal Recessive Spastic Paraplegia Type 75 at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Knobloch Syndrome | Cutaneous Lupus Erythematosus | Goiter, Nodular | Oculopharyngeal Muscular Dystrophy | Neurocutaneous Melanocytosis | Sickle Cell Anemia | Takenouchi-Kosaki Syndrome | Bare Lymphocyte Syndrome | Progressive Myoclonic Epilepsy | Congenital Muscular Dystrophy | Jawad Syndrome | Parkinson Disease 6, Autosomal Recessive Early-onset | Stromal Corneal Dystrophy | Menetrier Disease | Miyoshi Myopathy | DEND Syndrome | Schnyder Crystalline Corneal Dystrophy | Congenital Nephrotic Syndrome | Charcot-Marie-Tooth Disease, Type 2 | Gastroenteritis | Dementia | Paracoccidioidomycosis | Diabetic Neuropathy | Central Retinal Artery Occlusion | Spinal Cord Diseases | KBG Syndrome | Hepatoblastoma | Vascular Calcification | Obsessive-compulsive Disorder | Progressive Familial Intrahepatic Cholestasis | Retinitis | Microcephalic Primordial Dwarfism | Hereditary Sensory Neuropathy Type 1 | Extramammary Paget's Disease | Transthyretin-related Amyloidosis | Burn-McKeown Syndrome | Spinocerebellar Ataxia Type 17 | Clouston Hidrotic Ectodermal Dysplasia | Blepharo-cheilo-odontic Syndrome | Costello Syndrome | Contact Dermatitis | Schizotypal Personality Disorder | Cholangiocarcinoma | Hypokalemia | Pycnodysostosis | Cystinuria | Spinocerebellar Ataxia Type 28 | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Large Granular Lymphocytic Leukemia | Pantothenate Kinase-associated Neurodegeneration | Facioscapulohumeral Muscular Dystrophy | Leber Congenital Amaurosis | Central Core Disease | Alazami Syndrome | Lyme Disease | Choroiditis | Dermatofibrosarcoma | Thromboembolism | Acute Myeloid Leukemia | Familial Hypertrophic Cardiomyopathy | Primary Hyperoxaluria Type 3 | Blue Rubber Bleb Nevus Syndrome | Whipple's Disease | Myelofibrosis | Mitochondrial DNA Depletion Syndrome 13 | Hypersensitivity | Paronychia | Infectious Diarrhea | Muir-Torre Syndrome | Macrophage Activation Syndrome | Inflammatory Joint Disease | Hypertrophy | Postpartum Depression | Wolman Disease | Rickets | Avellino Corneal Dystrophy | Acute Tubular Necrosis | Purpura | Rothmund-Thomson Syndrome | Dysplastic Nevus | Congenital Hemolytic Anemia | Hashimoto Thyroiditis | Charcot-Marie-Tooth Disease Type 4E | Colitis | Cushing Syndrome | Glutathione Synthetase Deficiency | Autoimmune Polyendocrine Syndrome | Melanoma, Malignant | Glomerulonephritis, Membranoproliferative | Exostoses | Hennekam Lymphangiectasia-lymphedema Syndrome | Meconium Ileus | Alcoholism | Osteitis | Takayasu's Arteritis | Oligodendroglioma | Osteomalacia | Barrett Esophagus | Prediabetes | Microcephaly | Intestinal Tuberculosis | Lymphedema-distichiasis Syndrome | Renpenning Syndrome | Sensory Neuropathy | Hypertension, Renal | Spinal Muscular Atrophy Type 2 | Multiple Myeloma | Gangliosidosis | Cockayne Syndrome | Chylomicron Retention Disease | Spasticity | Giant Cell Arteritis | Spitzoid Melanoma | Diverticulitis | Charcot-Marie-Tooth Disease Type 3 | Auriculocondylar Syndrome | Noonan Syndrome-like Disorder With Loose Anagen Hair | Multiple Sclerosis, Chronic Progressive | Lathosterolosis | Agranulocytosis | Waldenstrom Macroglobulinemia | Fowler's Syndrome | Diabetes Insipidus, Nephrogenic | Epidermolytic Hyperkeratosis | 3-hydroxy-3-methylglutaric Aciduria | Smith-Lemli-Opitz Syndrome | Cardiac Sarcoidosis | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Greenberg Dysplasia | Hyperandrogenemia | Meesmann Corneal Dystrophy | Neuroleptic Malignant Syndrome | Persistent Fetal Circulation | Spitz Nevus | DICER1 Syndrome | Familial Digital Arthropathy-brachydactyly | Hypoparathyroidism | Nephrosclerosis | Malignant Fibrous Histiocytoma | Chronic Idiopathic Myelofibrosis | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Hyperthyroidism | Jalili Syndrome | Asthma, Nocturnal | Brugada Syndrome 1 | Hemimegalencephaly | Antisynthetase Syndrome | Lymphoma, Primary Cutaneous Anaplastic Large Cell | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Myasthenia | Oculocutaneous Albinism Type 2 | Pneumonia, Mycoplasma | Light Chain Amyloidosis | Polymyalgia Rheumatica | Hypoalbuminemia | Congenital Hereditary Endothelial Dystrophy Type II | Warsaw Breakage Syndrome | Thyroiditis | Subacute Sclerosing Panencephalitis | Dysferlinopathy | Anxiety Disorders | Sarcomatoid Carcinoma Of The Lung | REM Sleep Behavior Disorder | Androgenic Alopecia | Venous Insufficiency | Wagner Disease | Neurotoxicity | IgA Nephropathy | Shock, Cardiogenic | Osteopathia Striata With Cranial Sclerosis | Fibrillation, Atrial | Pachyonychia Congenita | Blastomycosis | Stevens-Johnson Syndrome | Cholera | X-linked Acrogigantism | Zimmermann-Laband Syndrome | Glycogen Storage Disease Type 1 | Trichomegaly | Spinocerebellar Ataxia Type 1 | Basan Syndrome | Seizures | Mabry Syndrome | Angioedema, Acquired | Carey-Fineman-Ziter Syndrome | Teratozoospermia | Atopic Dermatitis | Priapism | Intracerebral Hemorrhage | Hypertensive Nephropathy | Nail-Patella Syndrome | Sarcoma, Alveolar Soft Part | Galactosemia | Frontotemporal Dementia | Thyroiditis, Autoimmune | Kaposi Sarcoma | Essential Fructosuria | Presbycusis | Epicondylitis | Primary Biliary Cholangitis | Alkaptonuria | Dysgerminoma | Carbohydrate Metabolism Disorders | Hemophilia | Inflammatory Myofibroblastic Tumor | Ehlers-Danlos Syndrome With Progressive Kyphoscoliosis, Myopathy, And Hearing Loss | Hypogonadism | Infertility | Heart Block | Chediak-Higashi Syndrome | Angina Pectoris | Periventricular Nodular Heterotopia | Acute Leukemia | Hyperuricemia | Sporadic Inclusion Body Myositis | Cancer, Skin | Carcinoma, Signet Ring Cell | Chorioretinitis | Huntington's Disease | Bardet-Biedl Syndrome | Distal Myopathy | Retinopathy Of Prematurity | Mitochondrial Cytopathy | Cancer, Breast | Amyotrophic Lateral Sclerosis | Proctitis | Down Syndrome | Li-Fraumeni Syndrome | Martsolf Syndrome | Hepatitis, Chronic | Olmsted Syndrome | Duchenne Muscular Dystrophy | Hemoglobinopathies | CHARGE Syndrome | Farber Disease | Chronic Neutrophilic Leukemia | Cancer, Brain | Exocrine Pancreatic Insufficiency | Fuchs Dystrophy | T-cell Lymphoma, Subcutaneous Panniculitis-like | Macrodactyly | Autoimmune Autonomic Ganglionopathy | Encephalitis | Pulmonary Capillary Hemangiomatosis | Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis | Congenital Aniridia | Multiple System Atrophy | Neurocysticercosis | Chiari Malformation Type I | Spinocerebellar Ataxia Type 31 | Acrodermatitis Enteropathica | Mesothelioma, Malignant | Pancreatitis | Blepharitis | Heterotaxy | Glutaric Aciduria Type 2 | Central Pain Syndrome | Hypotrichosis | Crigler-Najjar Syndrome | Cystitis, Interstitial | Heroin Dependence | Holoprosencephaly | Ovarian Sex Cord-stromal Tumor | Dermatitis Herpetiformis | Sepiapterin Reductase Deficiency | Cantu Syndrome | Cryopyrin-associated Periodic Syndromes | Corneal Neovascularization | Cranial Nerve Disease | Cutaneous Mastocytosis | Retinal Vasculitis | Parkinsonism | Larsen Syndrome | Encephalopathy, Glycine | Familial Retinal Arterial Macroaneurysm | Sitosterolemia | Basal Ganglia Disease, Biotin-responsive | Waardenburg Syndrome Type 4 | Joubert Syndrome | Anorexia Nervosa | Hypertension, Essential | Beare-Stevenson Syndrome | Meningeal Melanocytoma | Juvenile Myoclonic Epilepsy | Schwannoma | Pulmonary Sclerosing Hemangioma | Adams-Oliver Syndrome | Urea Cycle Disorder | Vitiligo | Hyperlipidemia Type V | Adenosine Deaminase Deficiency | Astrocytoma | Lipid Storage Myopathy | VACTERL/VATER Association | Enterocolitis, Necrotizing | Galactosialidosis | Hydrocephalus | Hereditary Coproporphyria | Budd-Chiari Syndrome | Conjunctivitis | Pulmonary Stenosis | Hypothyroidism | T-cell Prolymphocytic Leukemia | Pyoderma Gangrenosum | Enhanced S-cone Syndrome | Fibronectin Glomerulopathy | Pulverulent Zonular Cataract | Aplasia Cutis Congenita | Nutrition Disorders | Wolfram Syndrome | Cryoglobulinemia | Wolff-Parkinson-White Syndrome | Bulimia Nervosa | Cholangitis | Pelvic Inflammatory Disease | Myotonia | Thrombasthenia | Arthritis, Psoriatic | Crimean-Congo Hemorrhagic Fever | Currarino Syndrome | Pulmonary Alveolar Microlithiasis | Cerebrotendinous Xanthomatosis | Lymphangiomatosis | C3 Glomerulopathy | Paraganglioma | Dysmorphophobia | Von Willebrand Disease | Otopalatodigital Syndrome Type 2 | Relapsing Polychondritis | Pheochromocytoma | Wiskott-Aldrich Syndrome | Christianson Syndrome | PHARC Syndrome | Thyrotoxic Periodic Paralysis | Pendred Syndrome | Congenital Torticollis | Bainbridge-Ropers Syndrome | Supravalvular Aortic Stenosis | Cocaine-Related Disorders | Axenfeld-Rieger Syndrome | Granuloma Annulare | High Molecular Weight Kininogen Deficiency | Anorectal Malformations | Acute Lymphocytic Leukemia | Hemochromatosis Type 1 | Antley-Bixler Syndrome | Small Lymphocytic Lymphoma | Cervical Dystonia | Stickler Syndrome | Trichuriasis | Anovulation | Methemoglobinemia | Vitamin B12 Deficiency | Fibrosarcoma | Schindler Disease | Fundus Albipunctatus | Arthritis, Gouty | Corneal Edema | Aneurysm, Thoracic Aortic | Hypodontia | Fuchs Heterochromic Iridocyclitis | Peeling Skin Syndrome, Acral Type | GLUT1 Deficiency Syndrome | Sickle Cell Disease | Ectrodactyly | Angiomyolipoma | Nemaline Myopathy 10 | Graft-versus-host Disease | Nasodigitoacoustic Syndrome | Adenoid Cystic Carcinoma | Arrhythmogenic Right Ventricular Cardiomyopathy | Infantile Refsum Disease | Retinoschisis | Frontometaphyseal Dysplasia | Rhabdomyosarcoma | Coffin-Lowry Syndrome | Pseudo-pseudohypoparathyroidism | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Leishmaniasis, Visceral | Loeys-Dietz Syndrome Type 4 | Microcephaly, Seizures, And Developmental Delay | Polyneuropathy | Pregnancy, Ectopic | LRBA Deficiency | Learning Disability | Smoldering Myeloma | Optic Nerve Diseases | Inflammatory Bowel Disease | Charcot-Marie-Tooth Disease, Type 2C | Porphyria Cutanea Tarda | Esophageal Motility Disorders | Spinocerebellar Ataxia Type 12 | Glanzmann Thrombasthenia | Joubert Syndrome 2 | Trigonocephaly | Greig Cephalopolysyndactyly Syndrome | Adenoma, Villous | Anal Fissure | Occipital Neuralgia | Liddle Syndrome