Pseudo-pseudohypoparathyroidism

About the Disease
Pseudohypoparathyroidism, Type Ia, also known as albright's hereditary osteodystrophy, is related to hyperphosphatemia and congenital hypothyroidism, and has symptoms including seizures An important gene associated with Pseudohypoparathyroidism, Type Ia is GNAS (GNAS Complex Locus), and among its related pathways/superpathways are Signal Transduction and GPCR downstream signalling. The drugs Theophylline and Benzocaine have been mentioned in the context of this disorder. Affiliated tissues include bone, skin and thyroid, and related phenotypes are pseudohypoparathyroidism and precocious puberty

Common Targets
PTH | SNURF | GNAS | IGF2 | PRKAR1A | GNAS

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