Disease

Prader-Willi Syndrome

About the Disease
Prader-Willi Syndrome, also known as prader-labhart-willi syndrome, is related to schaaf-yang syndrome and angelman syndrome. An important gene associated with Prader-Willi Syndrome is MAGEL2 (MAGE Family Member L2), and among its related pathways/superpathways is Prader-Willi and Angelman syndrome. The drugs Liraglutide and Insulin have been mentioned in the context of this disorder. Affiliated tissues include pituitary, skin and brain, and related phenotypes are global developmental delay and delayed speech and language development

Common Targets
SLC6A2 | TAS2R4 | GH1 | TAS2R10 | TRPV2 | PDE10A | G3480 | TCF4 | GIP | LEP | OXT | SNRPN | TAS2R31 | HTR2A | SLC6A4 | ADRB1 | TAS2R30 | MC3R | UQCRC2 | K(ATP) Channel (nonspecified subtype) | TRPA1 | PPP2R5D | HRH1 | LEPR | GHR | Taste receptor type 2 (nonspecified subtype) | SNURF | GABRA5 | EHMT2 | MC4R | GPR55 | OCA2 | SLC6A3 | METAP2 | MAGEL2 | OXTR | MAOB | USP9X | OPRM1 | MCHR1 | MC1R | MBOAT4 | HRH3 | TRPM8 | GHSR | CNR1 | FBN1 | MAOA | TRPV1

疾病靶点研报
Prader-Willi Syndrome

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