McLeod Syndrome

About the Disease
Mcleod Syndrome, also known as mcleod neuroacanthocytosis syndrome, is related to choreoacanthocytosis and huntington disease. An important gene associated with Mcleod Syndrome is XK (X-Linked Kx Blood Group Antigen, Kell And VPS13A Binding Protein). Affiliated tissues include spinal cord, heart and tongue, and related phenotypes are rhabdomyolysis and dysarthria

Common Targets
CYBB | XK

Note: If you'd like to get a target analysis report for McLeod Syndrome, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of McLeod Syndrome at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Oligodendroglioma | Keratitis | Malignant Fibrous Histiocytoma | Parkinson's Disease | VACTERL Association | Ichthyosis, X-linked | Small Lymphocytic Lymphoma | Low Tension Glaucoma | Retinal Diseases | Loeys-Dietz Syndrome | Neurofibromatosis Type 1 | Sandhoff Disease | Macrodactyly | Haim-Munk Syndrome | Carcinoid Syndrome | Spinal And Bulbar Muscular Atrophy | Glutaric Aciduria Type 3 | Cataract | Ligneous Conjunctivitis | Microcephaly, Seizures, And Developmental Delay | Osteogenesis Imperfecta Type VI | Progressive Osseous Heteroplasia | Lymphomatoid Granulomatosis | Primary Carnitine Deficiency | Acute Leukemia | Congenital Sodium Diarrhea | Congenital Adrenal Hyperplasia 1 | Hepatorenal Syndrome | Hyperoxaluria | Werner's Syndrome | Hypoparathyroidism | Inflammatory Myopathy | Myoclonus-dystonia Syndrome | Recurrent Respiratory Papillomatosis | Ulcerative Colitis | Malonyl-CoA Decarboxylase Deficiency | Osteogenesis Imperfecta Type II | Christianson Syndrome | Fascioliasis | Liebenberg Syndrome | Keratoconjunctivitis | Pneumonia, Viral | Atopic Dermatitis | Japanese Encephalitis | Autosomal Recessive Spastic Paraplegia Type 54 | Peripheral Neuropathy | Premenstrual Syndrome | Retinal Degeneration | Myopathy | Arteriovenous Malformations | Alexander Disease | Hypertension, Portal | Keratoacanthoma | Progressive Familial Intrahepatic Cholestasis Type 1 | Zygomycosis | NDH Syndrome | Kearns-Sayre Syndrome | Charcot-Marie-Tooth Disease, Type 1A | Osteonecrosis | Leiomyoma | Sialidosis | Salla Disease | Chronic Neutrophilic Leukemia | Kohlschutter-Tonz Syndrome | Hydrops Fetalis | Gestational Trophoblastic Disease | Colorectal Adenoma | Seminoma | Holoprosencephaly | IMAGe Syndrome | Teratozoospermia | Tyrosinemia Type 2 | Williams Syndrome | Motion Sickness | Pemphigoid | Warsaw Breakage Syndrome | Ectopia Lentis, Isolated, Autosomal Recessive | Metanephric Adenoma | Bronchitis | Hypersensitivity Pneumonitis | Familial Hyperaldosteronism | Avellino Corneal Dystrophy | Meningeal Melanocytoma | Varicocele | HANAC Syndrome | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Cervicitis | Prolymphocytic Leukemia | Alopecia Totalis | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Cystitis | Neurocutaneous Melanocytosis | Osteogenesis Imperfecta Type V | Encephalopathy | Neuroendocrine Cancer | Lupus Erythematosus | Hypertension, Essential | Epidermolytic Ichthyosis, Annular | Myhre Syndrome | Crisponi Syndrome | Methemoglobinemia | Hepatitis A | Familial Male-limited Precocious Puberty | Hepatitis, Autoimmune | Spinocerebellar Ataxia Type 28 | MIRAGE Syndrome | Choroideremia | Hyperacusis | Usher Syndrome Type I | Optic Neuritis | Pleural Tuberculosis | Tenosynovial Giant Cell Tumor | Adult Polyglucosan Body Disease | Urticaria | Parapsoriasis | Chordoid Glioma | Oculopharyngeal Muscular Dystrophy | Familial Mediterranean Fever | Monilethrix | Neurodegeneration Due To Cerebral Folate Transport Deficiency | Osteogenesis Imperfecta Type I | Ocular Surface Squamous Neoplasia | Hypogonadism | Hyperglycemia | Neurofibroma | Tuberculous Meningitis | Sickle Cell Anemia | FG Syndrome | Chronic Idiopathic Myelofibrosis | Allan-Herndon-Dudley Syndrome | Melanoma, Uveal | Phenylketonuria II | Milk Allergy | Schwannoma | Hepatoblastoma | Priapism | Chylomicron Retention Disease | Pachyonychia Congenita | Li-Fraumeni Syndrome | Urethritis | Joubert Syndrome 2 | Pneumococcal Meningitis | Spinocerebellar Ataxia Type 16 | Adenoma, Pituitary | Generalized Epilepsy And Paroxysmal Dyskinesia | Endocarditis | Mitochondrial Cytopathy | Retinal Telangiectasia | Early Infantile Epileptic Encephalopathy 13 | Spondyloperipheral Dysplasia | Hennekam Lymphangiectasia-lymphedema Syndrome | Melnick-Needles Syndrome | Spondylometaphyseal Dysplasia | Porphyria | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Kleine-Levin Syndrome | Cerebrotendinous Xanthomatosis | Fontaine Progeroid Syndrome | Thrombotic Microangiopathy | Discoid Lupus Erythematosus | Retinitis Pigmentosa | Hemosiderosis | Enterocolitis, Necrotizing | Vitamin B12 Deficiency | Cheilitis | Meningococcal Meningitis | Metaphyseal Chondrodysplasia, Schmid Type | Thymoma, Malignant | Oligoasthenoteratozoospermia | Dentinogenesis Imperfecta | N-acetylglutamate Synthase Deficiency | Renal Medullary Carcinoma | Chitayat Syndrome | Retinitis Pigmentosa 3 | Benign Recurrent Intrahepatic Cholestasis 1 | Blepharophimosis Syndrome | Adrenal Insufficiency | Anti-glomerular Basement Membrane Disease | Chondrosarcoma | Duchenne Muscular Dystrophy | Hyperbilirubinemia | Hypophosphatasia | Acrodermatitis Enteropathica | Uterine Leiomyoma | Multicystic Renal Dysplasia | Pelizaeus-Merzbacher Disease | Urea Cycle Disorder | Dermatofibrosarcoma | Bronchiectasis | Lymphopenia | Metachromatic Leukodystrophy | Charcot-Marie-Tooth Disease, Type 2 | Demyelinating Diseases | Polycythemia | Multiple Sclerosis, Chronic Progressive | Nemaline Myopathy 8 | DiGeorge Syndrome | Amish Infantile Epilepsy Syndrome | Prader-Willi Syndrome | Nicolaides-Baraitser Syndrome | GM2-gangliosidosis AB Variant | Homocystinuria | Charcot-Marie-Tooth Disease Type 2E | Chronic Lymphocytic Leukemia | Tremor | Takayasu's Arteritis | Aicardi-Goutieres Syndrome | Specific Granule Deficiency | Parkinson Disease 6, Autosomal Recessive Early-onset | Plasma Cell Leukemia | Spinocerebellar Ataxia Type 23 | Schwannomatosis | Mucormycosis | Leukodystrophies | Glomerulonephritis | Osteogenesis Imperfecta Type IV | Erythrokeratodermia Variabilis | B-cell Chronic Lymphocytic Leukemia | Donnai-Barrow Syndrome | LRBA Deficiency | Colitis, Collagenous | Chiari Malformation Type I | Gynecomastia | 5-oxoprolinase Deficiency | Progressive Familial Intrahepatic Cholestasis | Colitis, Microscopic | Nicotine Dependence | Tumoral Calcinosis | Lymphedema | Ependymoma | Pulmonary Veno-occlusive Disease | Carcinoma In Situ | Cornelia De Lange Syndrome | Anosmia, Congenital | Cervical Dystonia | Hypertrophy | POEMS Syndrome | Blepharo-cheilo-odontic Syndrome | Menetrier Disease | Corticobasal Syndrome | GLUT1 Deficiency Syndrome | Orthostatic Intolerance | Acute Lymphocytic Leukemia | Trimethylaminuria | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Cranioectodermal Dysplasia | Malnutrition | Canavan Disease | Succinic Semialdehyde Dehydrogenase Deficiency | Sick Sinus Syndrome | Carbonic Anhydrase VA Deficiency | Strabismus | Pupil Disorders | Moyamoya Disease | Melanoma | Microphthalmia, Syndromic 7 | Greenberg Dysplasia | Nail Disorder, Nonsyndromic Congenital | Congenital Hereditary Endothelial Dystrophy Type II | Erythropoietic Protoporphyria | Blepharospasm | Atelosteogenesis Type 1 | Hyperphenylalaninemia | Distal Spinal Muscular Atrophy | Scoliosis | Fanconi Syndrome | Keratocystic Odontogenic Tumor | Corneal Neovascularization | Granuloma Annulare | Bipolar Disorder | Ovarian Sex Cord-stromal Tumor | Eccrine Porocarcinoma | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | Premature Ejaculation | Glanzmann Thrombasthenia | Waardenburg Syndrome | Intermittent Explosive Disorder | Histoplasmosis | Birk-Barel Syndrome | Microcephaly | Arterial Tortuosity Syndrome | Okihiro Syndrome | Cri-du-chat Syndrome | Zimmermann-Laband Syndrome | Bartter Syndrome | Hyper IgE Syndrome | Acanthosis Nigricans | Aneurysm, Thoracic Aortic | Prune Belly Syndrome | Cerebellofaciodental Syndrome | Inflammatory Bowel Disease | Saethre-Chotzen Syndrome | Autosomal Recessive Congenital Ichthyosis | Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis | Chondrodysplasia Punctata 2, X-linked Dominant | Best Macular Dystrophy | Bernard-Soulier Syndrome | Hepatitis C, Chronic | Oguchi Disease-2 | Polymicrogyria | Stomatitis | 3-hydroxy-3-methylglutaric Aciduria | Esophagitis, Eosinophilic | Schindler Disease | Rift Valley Fever | Oculocutaneous Albinism Type 4 | Bloom Syndrome | 3-methylglutaconic Aciduria | Lafora Disease | Atrial Septal Defect | Coronary Restenosis | Keratosis, Actinic | Zollinger-Ellison Syndrome | Headache | GNE Myopathy | Craniofacial Dysostosis | Diabetic Encephalopathy | Hypercalciuria | Pitt-Hopkins Syndrome | Neuronal Ceroid Lipofuscinosis | Mucolipidosis Type III | Infantile Refsum Disease | Brugada Syndrome 1 | Muir-Torre Syndrome | Carcinoma, Transitional Cell | Osteoporosis, Postmenopausal | Blepharitis | Castleman Disease | Spina Bifida | Campomelic Dysplasia | Allergic Contact Dermatitis | Congenital Myopathy | Neutropenia | Cabezas Syndrome | Congenital Nystagmus | Pre-eclampsia | Rothmund-Thomson Syndrome | Nevus | Chronic Inflammatory Demyelinating Polyneuropathy | Acne Vulgaris | Sarcoidosis, Pulmonary | Amyotrophic Lateral Sclerosis, Juvenile | Kabuki Syndrome 2 | Myositis, Focal | Lymphoma, Primary Cutaneous Anaplastic Large Cell | Shock, Cardiogenic | Hyperlipidemia Type V | Thanatophoric Dysplasia | Meckel-Gruber Syndrome | Hemophilia | Primary Erythromelalgia | Cherubism | Leukoencephalopathy, Progressive Multifocal | Necrobiosis Lipoidica | Cirrhosis | Congenital Absence Of Vas Deferens | Speech Disorders | Megalencephaly | Porphyria Cutanea Tarda | Xeroderma Pigmentosum Variant Type | Spinal Cord Diseases | Gastroenteritis | Gliosarcoma | Bethlem Myopathy | Bursitis | Endophthalmitis | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Calcium Pyrophosphate Deposition Disease | LEOPARD Syndrome | Congenital Dysfibrinogenemia | Norrie Disease | Metabolic Diseases | Optic Neuropathy | Eosinophilia | Enhanced S-cone Syndrome | Hermansky-Pudlak Syndrome | Venous Insufficiency | Neuromyotonia | Creatine Deficiency Syndrome Due To AGAT Deficiency | Swine Influenza | Trigonocephaly | Bacterial Meningitis | Pancreatitis | 3-methylcrotonyl-CoA Carboxylase Deficiency | Hereditary Xerocytosis | Mesothelioma, Malignant | Compartment Syndrome | Mucolipidosis | Myocardial Infarction | Hypocalcemia | Sialoadenitis | Alpha-1 Antitrypsin Deficiency | Paroxysmal Kinesigenic Dyskinesia | Neuromuscular Disorders | Jalili Syndrome | 3-methylglutaconic Aciduria Type I | Adams-Oliver Syndrome | Occipital Neuralgia | Urolithiasis | Platyspondylic Lethal Skeletal Dysplasia, Torrance Type