Disease

Methemoglobinemia

About the Disease
Methemoglobinemia is related to congenital methemoglobinemia and methemoglobinemia and ambiguous genitalia, and has symptoms including cyanosis An important gene associated with Methemoglobinemia is CYB5R3 (Cytochrome B5 Reductase 3), and among its related pathways/superpathways are Metabolism and Cellular responses to stimuli. The drugs Methylthioninium and Levoleucovorin have been mentioned in the context of this disorder. Affiliated tissues include heart, skin and whole blood, and related phenotypes are no effect and no effect

Common Targets
HBA1 | HBA2 | CYB5R3 | HBB

疾病靶点研报
Methemoglobinemia

Note: If you'd like to get a target analysis report for Methemoglobinemia, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Methemoglobinemia at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Succinic Semialdehyde Dehydrogenase Deficiency | Encephalopathy | Wolman Disease | Chondrosarcoma | Synpolydactyly | Bacterial Meningitis | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Psoriasis | Ameloblastoma | Familial Cerebral Amyloid Angiopathy | Myhre Syndrome | Charcot-Marie-Tooth Disease Type 4E | N-acetylglutamate Synthase Deficiency | Hyperinsulinism-hyperammonemia Syndrome | Pemphigus | Usher Syndrome | Autonomic Neuropathy | Lissencephaly 2 | Pre-eclampsia | Paraplegia | Stromal Corneal Dystrophy | Cancer, Lung | Neurodegeneration Due To Cerebral Folate Transport Deficiency | Pseudomyxoma Peritonei | Cataplexy | Fibrillation, Atrial | Mandibuloacral Dysplasia With Type A Lipodystrophy | Arteriosclerosis | Oculocutaneous Albinism Type 4 | Lipid Storage Myopathy | Shprintzen-Goldberg Syndrome | Obesity | Oculopharyngeal Muscular Dystrophy | Micropenis | Noonan Syndrome-like Disorder With Loose Anagen Hair | Retinal Dystrophy, Early-onset Severe | Beta-Propeller Protein-associated Neurodegeneration | Spinocerebellar Ataxia Type 10 | Inflammatory Myofibroblastic Tumor | Low Tension Glaucoma | Melnick-Needles Syndrome | Spinocerebellar Ataxia Type 21 | Dermatitis Herpetiformis | H Syndrome | Ovarian Hyperstimulation Syndrome | Bronchiolitis | Giant Cell Arteritis | Retinal Diseases | Asthma | Systemic Mastocytosis | Sleep Apnea, Central | Lewy Body Dementia | Amelanotic Melanoma | Eccrine Porocarcinoma | Brooke-Spiegler Syndrome | Dementia | Micro Syndrome | Epidermodysplasia Verruciformis | Carcinoma, Merkel Cell | Diabetes Insipidus, Nephrogenic | Autoimmune Disease | Dent Disease | Transcobalamin Deficiency | Congenital Hemolytic Anemia | Pitt-Hopkins Syndrome | Epilepsy, Generalized | Hyperthyroidism | Congenital Stationary Night Blindness | Papilledema | Pneumothorax | Meconium Ileus | Cardiofaciocutaneous Syndrome | Polycystic Ovary Syndrome | Olmsted Syndrome | Coloboma | Amyotrophic Lateral Sclerosis, Juvenile | Diabetic Neuropathy | Fetal And Neonatal Alloimmune Thrombocytopenia | Myopia | Axenfeld-Rieger Syndrome | Hypotonia-cystinuria Syndrome | Spondylometaphyseal Dysplasia | Basal Ganglia Disease, Biotin-responsive | Pseudohypoparathyroidism Type 2 | Vogt-Koyanagi-Harada Syndrome | Macrophagic Myofasciitis | Borjeson-Forssman-Lehmann Syndrome | Progressive Familial Intrahepatic Cholestasis Type 3 | FG Syndrome | Trimethylaminuria | Neurofibroma | Gigantism | Melanoma, Malignant | Subcortical Band Heterotopia | Endometritis | Infectious Diarrhea | Pure Autonomic Failure | Congenital Adrenal Hyperplasia 1 | Proteasome-associated Autoinflammatory Syndrome 2 | Alveolar Capillary Dysplasia | Epilepsy Of Infancy With Migrating Focal Seizures | Autosomal Recessive Congenital Ichthyosis | Cystitis | Rheumatoid Arthritis | Progressive Familial Intrahepatic Cholestasis | Sialidosis | Relapsing Polychondritis | Shwachman-Bodian-Diamond Syndrome | Giant Axonal Neuropathy | Antley-Bixler Syndrome | Sialidosis Type I | Cartilage Disorders | Porphyria, Variegate | Saul-Wilson Syndrome | Tinea | MIRAGE Syndrome | Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia | Coenzyme Q10 Deficiency | Familial Male-limited Precocious Puberty | Chondrodysplasia Punctata | Pseudohermaphroditism | Left Ventricular Noncompaction | Hypopituitarism | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Retinitis | Leishmaniasis, Cutaneous | Necrobiosis Lipoidica | Mucolipidosis | Ataxia-ocular Apraxia 2 | Osteopetrosis | Leukodystrophies | Torticollis | Niemann-Pick Disease | Intracranial Hypertension | Spermatocele | Duchenne Muscular Dystrophy | Pantothenate Kinase-associated Neurodegeneration | Chromosome 17q21.31 Deletion Syndrome | Carcinoma, Signet Ring Cell | Familial Hypobetalipoproteinemia | Camptocormia | Ameloblastic Carcinoma | Leiomyoma | Cholestasis | Veno-occlusive Disease | Rhabdomyosarcoma, Embryonal | Turner's Syndrome | Pontocerebellar Hypoplasia | Primary Cutaneous Amyloidosis | Lichen Sclerosus | Oculocutaneous Albinism | Acne | Familial Glucocorticoid Deficiency | Hereditary Hemorrhagic Telangiectasia | Basal Cell Nevus Syndrome | Vascular Cognitive Impairment | HIBCH Deficiency | Rothmund-Thomson Syndrome | Macrophage Activation Syndrome | Spinocerebellar Ataxia Type 42 | Bietti Crystalline Dystrophy | Myotonic Disorders | Hydrops Fetalis | Chronic Idiopathic Myelofibrosis | Presbyopia | Myoclonic Atonic Epilepsy | Myosin Storage Myopathy | Polyneuropathy | Carcinoid Syndrome | Anterior Segment Dysgenesis | Tendinopathy | Disseminated Intravascular Coagulation | Pyloric Stenosis, Infantile Hypertrophic | Esophageal Carcinoma | Stickler Syndrome | Iron Overload | Waardenburg Syndrome Type 4A | Charcot-Marie-Tooth Disease Axonal Type 2N | Sick Sinus Syndrome 1 | Spondylo-ocular Syndrome | Mycosis Fungoides | Chiari Malformation Type I | Primary Carnitine Deficiency | Charcot-Marie-Tooth Disease Type 2D | Delayed Sleep Phase Syndrome | Osteochondrosis | Dyslipidemia | Central Core Disease | Carbonic Anhydrase VA Deficiency | Spitz Nevus | Episodic Ataxia Type 2 | Hyperlipidemia Type V | Chordoma | Chronic Myelomonocytic Leukemia | Focal Facial Dermal Dysplasia | Familial Episodic Pain Syndrome | Sporadic Hemiplegic Migraine | Spinocerebellar Ataxia Type 13 | Stiff-man Syndrome | Bruck Syndrome | Persistent Truncus Arteriosus | Diarrhea | Nail-Patella Syndrome | Hyperglycemia | Gingivitis | Rhizomelic Chondrodysplasia Punctata | Craniosynostosis | Congenital Bilateral Absence Of Vas Deferens | Fanconi Syndrome | Crohn's Disease | Diabetic Encephalopathy | Coffin-Lowry Syndrome | Apraxia | Sarcoma | Neurofibromatosis Type 2 | Pachyonychia Congenita | Pneumococcal Meningitis | Kohlschutter-Tonz Syndrome | Congenital Disorders Of Glycosylation Type II | Pyruvate Decarboxylase Deficiency | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Familial Hemiplegic Migraine | Retinal Dystrophy | Barrett Esophagus | Burn-McKeown Syndrome | Autism Spectrum Disorders | Multisystemic Smooth Muscle Dysfunction Syndrome | Congenital Afibrinogenemia | Vitreoretinopathy, Proliferative | Ocular Albinism Type 1 | Thanatophoric Dysplasia Type 1 | Japanese Encephalitis | Vitamin A Deficiency | Hydrocephalus | Hashimoto Thyroiditis | Pain | Portal Vein Thrombosis | Goiter | Cyst | Carotid Artery Disease | Congenital Bile Acid Synthesis Defect | Brachial Plexus Neuropathy | Neurofibromatosis Type 1 | Trichorhinophalangeal Syndrome | Cholangiocarcinoma | Corneal Dystrophy | Von Hippel-Lindau Disease | Orotic Aciduria | Sclerosing Cholangitis | Lymphedema-distichiasis Syndrome | Acute Myeloid Leukemia | Multiple Congenital Anomalies-hypotonia-seizures Syndrome 2 | Adenoma, Villous | Rubinstein-Taybi Syndrome | Hemorrhoids | Priapism | Hypervalinemia | Hoyeraal-Hreidarsson Syndrome | Glycogen Storage Disease Type 5 | Blepharoconjunctivitis | Anorexia Nervosa | Spondylolisthesis | Congenital Hereditary Endothelial Dystrophy Type II | Dystrophy, Cone-rod | Keratopathy | Presbycusis | Osteomalacia | Creutzfeldt-Jakob Disease | Neonatal Progeroid Syndrome | Eiken Syndrome | Nephropathy | Reye Syndrome | Carcinoma, Small Cell | Hypokalemic Periodic Paralysis | Prolymphocytic Leukemia | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 1 | Holt-Oram Syndrome | Diastrophic Dysplasia | Infertility | Progressive Osseous Heteroplasia | Acute Kidney Injury | Vulvovaginitis | Waardenburg Syndrome | Usher Syndrome Type I | Epidermolytic Ichthyosis, Annular | X-linked Sideroblastic Anemia | Hemorrhage | Myocardial Infarction | Alpha-1 Antitrypsin Deficiency | Exocrine Pancreatic Insufficiency | Osteosarcoma | Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy | Early Infantile Epileptic Encephalopathy 28 | Sensory Neuropathy | Acute Anterior Uveitis | Pancreatitis, Chronic | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Alagille Syndrome | Syndactyly | Cri-du-chat Syndrome | Acromegaly | Ganglioneuroma | Periventricular Nodular Heterotopia | Spinal Muscular Atrophy | Lafora Disease | Macular Degeneration | Meniere's Disease | Strabismus | Histoplasmosis | Supravalvular Aortic Stenosis | Hyperkalemic Periodic Paralysis | Sleep Apnea | Saethre-Chotzen Syndrome | Spinal Muscular Atrophy Type 2 | Hemangioblastoma | Kaposiform Hemangioendothelioma | Joubert Syndrome | Larsen Syndrome | Osteopathia Striata With Cranial Sclerosis | Diabetes Insipidus, Neurogenic | Leukemia | Hypoparathyroidism | Behavioral Variant Of Frontotemporal Dementia | Encephalitis, Tick-borne | Antenatal Bartter Syndrome Type 1 | Galactosemia | Hypersensitivity Pneumonitis | Reflex Epilepsy | Lamellar Ichthyosis | Bernard-Soulier Syndrome | Robinow Syndrome | Lentigo | Cardiomyopathy, Dilated, 1L | Sepiapterin Reductase Deficiency | Cohen Syndrome | Thrombophilia | Polydactyly | Cystinosis | Astrocytoma, Anaplastic | Pontocerebellar Hypoplasia Type 7 | Varices | Patent Foramen Ovale | HELLP Syndrome | Heavy Chain Disease | Tetraplegia | Vitelliform Macular Dystrophy | Keratoconjunctivitis | Gliosarcoma | Hypersomnia | Diffuse Mesangial Sclerosis | Metachondromatosis | Intermittent Explosive Disorder | Fukuyama Congenital Muscular Dystrophy | Lattice Corneal Dystrophy Type 1 | Neural Tube Defect | Keratoacanthoma | Retinal Detachment | Porencephaly | Osteonecrosis Of The Jaw | Fetal Alcohol Syndrome | Episodic Ataxia Type 1 | Encephalopathy, Glycine | Oculodentodigital Dysplasia | Menkes Disease | Congenital Nystagmus | Spinocerebellar Ataxia Type 40 | Van Der Knaap Disease | Thyrotoxic Periodic Paralysis | Epithelial-myoepithelial Carcinoma | Meningioma | Epilepsy | Lymphoma, AIDS-related | Congenital Lipoid Adrenal Hyperplasia | Osteogenesis Imperfecta Type IV | Carey-Fineman-Ziter Syndrome | Essential Fructosuria | Vici Syndrome | Meesmann Corneal Dystrophy | Warsaw Breakage Syndrome | Neurofibroma, Plexiform | Corneal Dystrophy And Perceptive Deafness | Cryptosporidiosis | Gynecomastia | Multicystic Renal Dysplasia | Angioedema, Hereditary | Sponastrime Dysplasia | Noonan Syndrome | Sotos Syndrome | Peroxisomal Disorder | Ependymoma | Colitis, Microscopic | Giant Cell Glioblastoma | Spinocerebellar Ataxia Type 7 | Pulverulent Zonular Cataract | Wolcott-Rallison Syndrome | Heart Failure | Migraine | Polymyositis | IgA Nephropathy | Spinocerebellar Ataxia Type 12