Disease

Hemochromatosis

About the Disease
Hemochromatosis Type 2, also known as juvenile hemochromatosis, is related to hemochromatosis, type 2b and rare hereditary hemochromatosis, and has symptoms including abdominal pain, constipation and diarrhea. An important gene associated with Hemochromatosis Type 2 is HJV (Hemojuvelin BMP Co-Receptor), and among its related pathways/superpathways are Transport of inorganic cations/anions and amino acids/oligopeptides and Insulin receptor recycling. The drugs Iron and Deferiprone have been mentioned in the context of this disorder. Affiliated tissues include liver, pancreas and heart, and related phenotypes are congenital hepatic fibrosis and elevated transferrin saturation

Common Targets
GNPAT | HAMP | ST14 | HFE | SUGP2 | PNPLA3 | PIGA | TMPRSS6 | DGUOK | TM6SF2 | PCSK7 | MBOAT7 | SLC40A1 | SLC11A2 | BMP6 | HJV | TFR2 | APP | UGT1A1 | KRR1 | UBE2O | RIPK1

疾病靶点研报
Hemochromatosis

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