Hemochromatosis

About the Disease
Hemochromatosis Type 2, also known as juvenile hemochromatosis, is related to hemochromatosis, type 2b and rare hereditary hemochromatosis, and has symptoms including abdominal pain, constipation and diarrhea. An important gene associated with Hemochromatosis Type 2 is HJV (Hemojuvelin BMP Co-Receptor), and among its related pathways/superpathways are Transport of inorganic cations/anions and amino acids/oligopeptides and Insulin receptor recycling. The drugs Iron and Deferiprone have been mentioned in the context of this disorder. Affiliated tissues include liver, pancreas and heart, and related phenotypes are congenital hepatic fibrosis and elevated transferrin saturation

Common Targets
GNPAT | HAMP | ST14 | HFE | SUGP2 | PNPLA3 | PIGA | TMPRSS6 | DGUOK | TM6SF2 | PCSK7 | MBOAT7 | SLC40A1 | SLC11A2 | BMP6 | HJV | TFR2 | APP | UGT1A1 | KRR1 | UBE2O | RIPK1

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Other Diseases

Infantile Liver Failure Syndrome 1 | Arteriosclerosis | Mitochondrial Cytopathy | 3-hydroxy-3-methylglutaric Aciduria | Persistent Hyperplastic Primary Vitreous | Pseudohypoparathyroidism Type 2 | Diverticulitis | Spinal And Bulbar Muscular Atrophy | Wolman Disease | Pouchitis | Keratoconjunctivitis | Adult Polyglucosan Body Disease | Coloboma | Anorectal Fistula | PASLI Disease | Immunoproliferative Disorders | Erythema Multiforme | Thyroid Hormone Resistance | Perivascular Epithelioid Cell Tumor | Cholangiocarcinoma | Glutaric Aciduria Type 2 | Usher Syndrome Type III | WAGR Syndrome | Gout | Lattice Corneal Dystrophy | Polyneuropathy | Nephritis, Interstitial | Incontinentia Pigmenti | Sensorineural Hearing Loss | Anorchia | Antenatal Bartter Syndrome Type 1 | Precocious Puberty | Cutis Laxa | Fraser Syndrome | Congenital Afibrinogenemia | Zygomycosis | Hyperostosis | B-cell Chronic Lymphocytic Leukemia | Imerslund-Grasbeck Syndrome | Common Cold | Pleural Tuberculosis | Dystonia 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Bile Acid Synthesis Defect | Angiodysplasia | Lipodystrophy | Melanocytic Nevus | Pityriasis Rubra Pilaris | Liver Failure, Acute Infantile | Cholangitis | Sezary Syndrome | Trismus-pseudocamptodactyly Syndrome | Portal Vein Thrombosis | Bone Marrow Necrosis | Zimmermann-Laband Syndrome | Hyperthyroidism | Oculocutaneous Albinism Type 2 | Carcinoma In Situ | Stevens-Johnson Syndrome | Hyper IgE Syndrome | Niemann-Pick Disease | Scabies | Sarcomatoid Carcinoma Of The Lung | Autosomal Recessive Bestrophinopathy | Wolfram Syndrome 2 | Gitelman Syndrome | Inflammatory Myopathy | Temporal Lobe Epilepsy | Chronic Beryllium Disease | Acrodermatitis Enteropathica | Fetal Alcohol Syndrome | Multiple Sclerosis, Primary Progressive | Early Infantile Epileptic Encephalopathy 1 | CHARGE Syndrome | Menkes Disease | Hypophosphatasia | Corneal Neovascularization | Combined Pituitary Hormone Deficiency | Urticaria | Birk-Barel Syndrome | Absence Epilepsy | Leprosy | Alstrom Syndrome | Takotsubo 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