Retinoblastoma

About the Disease
Familial Retinoblastoma, also known as hereditary retinoblastoma, is related to intraocular retinoblastoma and papilloma. An important gene associated with Familial Retinoblastoma is RB1 (RB Transcriptional Corepressor 1), and among its related pathways/superpathways are Gene expression (Transcription) and ERK Signaling. The drugs Nicotine and Miconazole have been mentioned in the context of this disorder. Affiliated tissues include eye, retina and brain, and related phenotypes are growth/size/body region and normal

Common Targets
G7124 | RASSF1 | APC | Mitogen-activated protein kinase p38 (MAPK p38) (nonspecified subtype) | G596 | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | G1026 | EPCAM | MEG3 | G6774 | HDAC2 | MYCT1 | G3569 | Protein Kinase B (PKB/Akt) (nonspecified subtype) | G598 | MIR34B | SOX30 | TOP1 | IKZF1 | MIR34C | SYK | G4170 | G999 | GPR151 | CHUK | MED4 | SOX9 | OTOR | DDX1 | G836 | PROM1 | RB1 | G4193 | G7157 | APC2 | KCNA1 | IL2 | TYMS | MBD4 | MAP4K2 | MYCN | ARL11 | VDR | MTHFR | FLT3

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