Zollinger-Ellison Syndrome

About the Disease
Zollinger-Ellison Syndrome, also known as gastrinoma, is related to multiple endocrine neoplasia and gastrinoma, and has symptoms including dyspepsia An important gene associated with Zollinger-Ellison Syndrome is GAST (Gastrin), and among its related pathways/superpathways are Class A/1 (Rhodopsin-like receptors) and GPCR downstream signalling. The drugs Dexlansoprazole and Lansoprazole have been mentioned in the context of this disorder. Affiliated tissues include pancreas, small intestine and pituitary, and related phenotypes are zollinger-ellison syndrome and peptic ulcer

Common Targets
CCKBR | Opioid receptor (nonspecified subtype) | QPCTL | CCKAR | Gastric H+/K+-ATPase | ABCC3

Note: If you'd like to get a target analysis report for Zollinger-Ellison Syndrome, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Zollinger-Ellison Syndrome at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Kernicterus | Skin Fragility-woolly Hair Syndrome | Juvenile Polyposis | Hydrops Fetalis | Anorexia Nervosa | Ileitis | Recurrent Respiratory Papillomatosis | Adenosine Deaminase 2 Deficiency | Pancytopenia | Disseminated Superficial Actinic Porokeratosis | Joubert Syndrome | Usher Syndrome Type IIC | Protein S Deficiency | Meckel-Gruber Syndrome | Hyperthyroidism | Pulmonary Stenosis | Lymphedema | Cerebral Amyloid Angiopathy | Thalassemia | Benign Familial Infantile Seizures | Combined Deficiency Of Factor V And Factor VIII | Acute Kidney Injury | Charcot-Marie-Tooth Disease Type 4 | Lysosomal Acid Lipase Deficiency | Pelizaeus-Merzbacher Disease | Hypertrophy | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Iron Deficiency Anemia | Spinocerebellar Ataxia Type 7 | Focal Facial Dermal Dysplasia | Netherton Syndrome | Hereditary Spastic Paraplegia | Spinocerebellar Ataxia Type 2 | Infantile Spasm | Cardiospondylocarpofacial Syndrome | Familial Exudative Vitreoretinopathy | Crigler-Najjar Syndrome | Renal Tubular Dysgenesis | Limb Girdle Muscular Dystrophy | Craniofrontonasal Syndrome | Hypermethioninemia | Spondylosis | Hartsfield Syndrome | Myelodysplasia | KBG Syndrome | Paraganglioma | Tuberculous Meningitis | Measles | Parkinson's Disease | Schizoaffective Disorder | Angelman Syndrome | Chronic Idiopathic Myelofibrosis | Chordoid Glioma | Congenital Ichthyosiform Erythroderma | Dowling-Degos Disease | Creatine Deficiency Syndrome | Presbyopia | Niemann-Pick Disease | Chronic Periodontitis | Optic Neuropathy | Cerebrovascular Disorders | Infantile Liver Failure Syndrome 1 | Bartter Syndrome | Diverticulitis | Pancreatitis, Chronic | Rhabdomyosarcoma, Embryonal | Adenylosuccinate Lyase Deficiency | Ectopia Lentis, Isolated, Autosomal Recessive | Blepharoconjunctivitis | Epidermodysplasia Verruciformis | Infantile Refsum Disease | Cryptosporidiosis | Diabetes | Primary Torsion Dystonia | Chronic Inflammatory Demyelinating Polyneuropathy | Lyme Disease | T-cell Lymphoma, Subcutaneous Panniculitis-like | Acute Generalized Exanthematous Pustulosis | Acute Chest Syndrome | Pantothenate Kinase-associated Neurodegeneration | Neuroendocrine Cancer | Autoimmune Autonomic Ganglionopathy | Sleep Apnea | Glycogen Storage Disease Type 5 | Nicotine Dependence | VACTERL/VATER Association | Primary Pigmented Nodular Adrenocortical Disease | Lymphoma, Primary Cutaneous Anaplastic Large Cell | Marshall-Smith Syndrome | Diabetes Type 1 | Glutaric Aciduria Type 2 | Multiple Sulfatase Deficiency | Thrombocytopenia | Ureteropelvic Junction Obstruction | Temtamy Preaxial Brachydactyly Syndrome | Ameloblastoma | Hypokalemic Periodic Paralysis | Melanoma, Malignant | Persistent Mullerian Duct Syndrome | Short-chain Acyl-CoA Dehydrogenase Deficiency | Hemochromatosis Type 1 | Chronic Leukemia | Nemaline Myopathy 10 | Leiomyoma | Retinal Telangiectasia | Alveolar Capillary Dysplasia | Hepatitis D | Congenital Fiber-type Disproportion Myopathy | Bethlem Myopathy | Fetal Akinesia Deformation Sequence | Sick Sinus Syndrome 1 | Vitamin D Deficiency | Atrioventricular Septal Defect | Asperger Syndrome | Mabry Syndrome | Lipid Storage Myopathy | Congenital Myasthenic Syndrome | Spasticity | Anal Fissure | Spinocerebellar Ataxia Type 12 | Dystonia Musculorum Deformans | Cystitis | Ghosal Syndrome | Corneal Neovascularization | Harlequin Ichthyosis | Charcot-Marie-Tooth Disease | Thanatophoric Dysplasia Type 1 | Sensorineural Hearing Loss | Martsolf Syndrome | Coloboma | ICF Syndrome | Sweet Syndrome | Premature Ejaculation | Rift Valley Fever | Pernicious Anemia | Hereditary Pyropoikilocytosis | Hypoproteinemia, Hypercatabolic | Dermatofibrosarcoma | Mosaic Variegated Aneuploidy Syndrome 2 | Hemoglobinopathies | Azoospermia | Carcinoid Tumor | Neovascular Glaucoma | Uveitis, Anterior | Avian Influenza | 5-oxoprolinase Deficiency | Multiple Myeloma | Hypercalciuria | Bone Giant Cell Tumor | Superficial Spreading Melanoma | Spondylocarpotarsal Synostosis Syndrome | Majeed Syndrome | Pemphigus Vulgaris | Glutaric Aciduria Type 3 | Fraser Syndrome | Hypobetalipoproteinemias | Blue Rubber Bleb Nevus Syndrome | Hypereosinophilic Syndrome | McCune-Albright Syndrome | Vogt-Koyanagi-Harada Syndrome | Benign Familial Neonatal Convulsions | Hypopigmentation | Non-proliferative Diabetic Retinopathy | Otitis Externa | Pyruvate Decarboxylase Deficiency | Primary Hyperoxaluria Type 1 | Coronary Artery Disease | Nicotine Addiction | Tetraplegia | Sialoadenitis | X-linked Charcot-Marie-Tooth Disease | Raine Syndrome | Lymphoma, Mantle Cell | Ichthyosis Bullosa Of Siemens | Microphthalmia, Syndromic 7 | Usher Syndrome Type II | Bulimia Nervosa | Holt-Oram Syndrome | Arthritis, Reactive | Cutaneous Angiosarcoma | Ophthalmoplegia | Congenital Central Hypoventilation Syndrome | Acrodysostosis | Chanarin-Dorfman Syndrome | Rotor Syndrome | Follicular Dendritic Cell Sarcoma | Dysequilibrium Syndrome | Wieacker-Wolff Syndrome | Bloom Syndrome | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Pure Red Cell Aplasia | Proteasome-associated Autoinflammatory Syndrome 2 | Sialidosis | Intestinal Pseudo-obstruction | Leukoplakia, Oral | Heroin Dependence | Microvillus Inclusion Disease | Spinocerebellar Ataxia Type 1 | ADNP Syndrome | Double Outlet Right Ventricle | Localized Scleroderma | Long QT Syndrome Type 1 | Spinocerebellar Ataxia Type 8 | Esophageal Adenocarcinoma | Colitis, Lymphocytic | Synpolydactyly | Pulmonary Capillary Hemangiomatosis | Down Syndrome | Marfan Syndrome | Tangier Disease | Tremor | Anovulation | Spitzoid Melanoma | Hepatitis, Chronic | Lactose Intolerance | Craniosynostosis | B-cell Prolymphocytic Leukemia | Poikiloderma With Neutropenia | Pyelonephritis | Blastomycosis | Carcinoma, Small Cell | Osteoporosis-pseudoglioma Syndrome | Lupus Erythematosus | Apparent Mineralocorticoid Excess Syndrome | Tendinitis | Fascioliasis | Stevens-Johnson Syndrome | Gardner Syndrome | Gyrate Atrophy Of The Choroid And Retina | Acute Lung Injury | IgA Nephropathy | Astigmatism | McLeod Syndrome | Acute Lymphocytic Leukemia | Fibronectin Glomerulopathy | Colitis, Microscopic | Myopia | Migraine | Tyrosinemia | Congenital Myopathy | Cranial Nerve Disease | Lymphomatoid Granulomatosis | Myocarditis | Polymicrogyria | Pupil Disorders | Metatropic Dysplasia | Hepatitis C, Chronic | AIDS | Pyruvate Kinase Deficiency | Intracranial Hypertension | Thyroid Dyshormonogenesis | Senior-Loken Syndrome | Encephalopathy | Erythropoietic Protoporphyria | Periventricular Nodular Heterotopia | Hyperammonemia | Paracoccidioidomycosis | Myocardial Infarction | Pathological Gambling | Arterial Tortuosity Syndrome | Neutrophilia | Glioblastoma | Glycogen Storage Disease Type 9 | Malaria | Megaloblastic Anemia | Johanson-Blizzard Syndrome | Acute Leukemia | Dysplastic Nevus | Nail Disorder, Nonsyndromic Congenital | GLUT1 Deficiency Syndrome | Retinitis Pigmentosa 3 | Multiple Congenital Anomalies-hypotonia-seizures Syndrome 2 | Nephrocalcinosis | Vascular Calcification | Angiosarcoma Of The Breast | Scabies | Amebiasis | Multiple Sclerosis, Chronic Progressive | Optic Neuropathy, Anterior Ischemic | Bullous Pemphigoid | Epidermolytic Hyperkeratosis | Micro Syndrome | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Strabismus | Cartilage Disorders | Hypophosphatasia | Rett Syndrome | Skin Carcinoma | Methemoglobinemia | Pseudohypoparathyroidism Type 1C | Donnai-Barrow Syndrome | Neutropenia | Hartnup Disease | NGLY1 Deficiency | Palmoplantar Keratoderma | GATA2 Deficiency | Alkaptonuria | Treacher Collins Syndrome | Chronic Mucocutaneous Candidiasis | Scleroderma, Diffuse | Oculocutaneous Albinism | Neurofibromatosis-Noonan Syndrome | Paraplegia | Nemaline Myopathy | Withdrawal Syndrome | Microcephalic Osteodysplastic Primordial Dwarfism, Type I | Muir-Torre Syndrome | Sclerosteosis 2 | Prurigo Nodularis | Currarino Syndrome | Schwartz-Jampel-Aberfeld Syndrome | Retinal Diseases | Pain | Gingivitis | Saul-Wilson Syndrome | Stromal Corneal Dystrophy | Crimean-Congo Hemorrhagic Fever | Chronic Thromboembolic Pulmonary Hypertension | Enterocolitis, Necrotizing | Histiocytic Sarcoma | Hereditary Coproporphyria | Primary Hyperoxaluria Type 3 | Alpha-1 Antitrypsin Deficiency | Bicuspid Aortic Valve | Hyperlipidemia, Familial Combined | Hypertension, Renovascular | Phenylketonuria | Familial Cerebral Amyloid Angiopathy | Congenital Heart Defects | Maple Syrup Urine Disease | Central Core Disease | Retinal Vasculitis | Schistosomiasis | Nephrotic Syndrome Type 1 | Inborn Errors Of Metabolism | Toxoplasmosis | Premenstrual Syndrome | Greenberg Dysplasia | Restless Legs Syndrome | Marinesco-Sjogren Syndrome | Spondylo-megaepiphyseal-metaphyseal Dysplasia | DiGeorge Syndrome | Abetalipoproteinemia | Acute Motor Axonal Neuropathy | DEND Syndrome | Heart Failure | Pneumonia, Bacterial | Liver Diseases | Scleritis | Diabetes Insipidus | Bardet-Biedl Syndrome | Asthma, Nocturnal | Pseudohypoparathyroidism Type 1A | Gaucher Disease | Nutrition Disorders | Megalencephaly | Keratitis-ichthyosis-deafness Syndrome | VACTERL Association | Congenital Stromal Corneal Dystrophy | Familial Digital Arthropathy-brachydactyly | Sleep Apnea, Central | Schwannomatosis | Takayasu's Arteritis | Atelosteogenesis Type 1 | Dubin-Johnson Syndrome | Panniculitis | Porencephaly | Gastroenteritis | Spina Bifida | Spinocerebellar Ataxia Type 28 | Oligospermia | Multifocal Motor Neuropathy | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Erythema Nodosum | Congenital Hypofibrinogenemia | Williams Syndrome | Erythematotelangiectatic Rosacea | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Vitamin B12 Deficiency | Syphilis | Schizotypal Personality Disorder | Necrotizing Autoimmune Myopathy | Keratosis, Actinic | Paronychia | Intermittent Explosive Disorder | Avellino Corneal Dystrophy | Veno-occlusive Disease | Osteoporosis, Postmenopausal | Mitochondrial Disease | Congenital Heart Block | Trichuriasis | Tyrosinemia Type 2 | Sulfite Oxidase Deficiency | HUPRA Syndrome | Dystonia-parkinsonism, X-linked | Hyperparathyroidism-jaw Tumor Syndrome | Autoimmune Disease | Stuve-Wiedemann Syndrome | Glomerulonephritis, Membranous | Angiosarcoma