Zollinger-Ellison Syndrome

About the Disease
Zollinger-Ellison Syndrome, also known as gastrinoma, is related to multiple endocrine neoplasia and gastrinoma, and has symptoms including dyspepsia An important gene associated with Zollinger-Ellison Syndrome is GAST (Gastrin), and among its related pathways/superpathways are Class A/1 (Rhodopsin-like receptors) and GPCR downstream signalling. The drugs Dexlansoprazole and Lansoprazole have been mentioned in the context of this disorder. Affiliated tissues include pancreas, small intestine and pituitary, and related phenotypes are zollinger-ellison syndrome and peptic ulcer

Common Targets
CCKBR | Opioid receptor (nonspecified subtype) | QPCTL | CCKAR | Gastric H+/K+-ATPase | ABCC3

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