Disease

Pathological Gambling

About the Disease
Pathological Gambling, also known as compulsive gambling, is related to polysubstance abuse and chronic pain. An important gene associated with Pathological Gambling is DRD2 (Dopamine Receptor D2), and among its related pathways/superpathways are Signal Transduction and GPCR downstream signalling. The drugs Acamprosate and Olanzapine have been mentioned in the context of this disorder. Affiliated tissues include prefrontal cortex, cortex and brain, and related phenotypes are no effect and no effect

Common Targets
Kainate Receptor (GluR) (nonspecified subtype) | Voltage-Gated Sodium Channel Complex | Sodium channel (nonspecified subtype) | SLC6A4 | OPRD1 | HTR2A | NF-kappaB (NFkB) | DRD5 | NMDA receptor | DRD1 | G7099 | CA2 | HTR1B | SLC5A1 | DRD3 | SLC6A3 | OPRM1 | OPRK1 | Glutamate Receptor Ionotropic AMPA Receptor | DRD2 | COMT | TTR | SLC6A2

疾病靶点研报
Pathological Gambling

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