Disease

Leri-Weill Dyschondrosteosis

About the Disease
Leri-Weill Dyschondrosteosis, also known as lwd, is related to madelung deformity and shox-related short stature. An important gene associated with Leri-Weill Dyschondrosteosis is SHOX (Short Stature Homeobox), and among its related pathways/superpathways is FGFR3 signaling in chondrocyte proliferation and terminal differentiation. Affiliated tissues include bone, skeletal muscle and eye, and related phenotypes are depressed nasal bridge and wide nasal bridge

Common Targets
SHOX | CYP26C1 | NPR2

疾病靶点研报
Leri-Weill Dyschondrosteosis

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