Disease

Fahr Disease

About the Disease
Basal Ganglia Calcification, also known as fahr's syndrome, is related to basal ganglia calcification, idiopathic, 1 and immunodeficiency 38 with basal ganglia calcification, and has symptoms including athetosis, cerebellar ataxia and muscle rigidity. An important gene associated with Basal Ganglia Calcification is SLC20A2 (Solute Carrier Family 20 Member 2), and among its related pathways/superpathways are Overview of interferons-mediated signaling pathway and S1P3 pathway. Affiliated tissues include cortex, brain and eye, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Common Targets
PDGFB | PDGFRB | MYORG | MIA2 | XPR1 | SLC20A2 | JAM2 | THAP1

疾病靶点研报
Fahr Disease

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