Disease

Leprosy

About the Disease
Leprosy 2, also known as leprosy, susceptibility to, 2, is related to leprosy 3 and oto-palatal-digital syndrome. An important gene associated with Leprosy 2 is PRKN (Parkin RBR E3 Ubiquitin Protein Ligase). The drugs Levoleucovorin and Folic acid have been mentioned in the context of this disorder. Affiliated tissues include skin, breast and neutrophil.

Common Targets
TLR1 | RIPK2 | CUBN | BBS9 | IL10 | IL18 | FCN2 | IL23R | C1orf141 | ADGB | IL22 | LINC00968 | HCN3 | G7124 | PPIA | Protein Phosphatase 2B | HLA-DQB1 | CRBN | NCKIPSD | ITSN2 | TNFRSF1B | LOC105377567 | IRGM | LRRK2 | H3-5 | ZFP36L1 | RAD52 | PARD3B | FLG | LOC105375721 | HIF1A | IFNGR1 | TOLLIP | PKLR | G6352 | CCDC88B | LOC105371082 | CARD9 | NINJ1 | ARL3 | ALDH2 | LTA | PPP3R2 | CSF1R | PPID | BATF3 | LACC1 | TYK2 | PPP3CC | DDX39A | SLC4A10 | TFAM | NOD2 | FREM1 | G7099 | BCL10 | HLA-B | MAP2K1 | MASP2 | SLC29A3 | PENK-AS1 | CTSZ | IL27 | IL12RB2 | LINC02471 | SOD2 | DUSP14 | HLA-DRB1 | HPR | EBF1 | LOC105369736 | JAG1 | TCN2 | LOC105378318 | LOC105371744 | SGSH | SYK | NFKBIL1 | POLG | CDH18 | MYBBP1A | MBL2 | FDPS | IL18RAP | CXCL12 | TNFRSF11A | DCX (DDB1-CUL4-X-box) E3 protein ligase complex | PAF1 | IL17F | TLR2 | LOC105369818 | ADAP1 | CR1 | GALNT18 | LOC105376512 | PACRG | KCNQ1 | TOX | SLC7A2 | G2069 | PRKCB | USP49 | LINC02555 | TNFSF15 | SLC22A5 | OPA1 | ZNF229 | LOC105370032 | PPP3CB | LINC02568 | PPP3R1 | ERP44 | TNFRSF8 | CFH | SLC11A1 | WTAP | GATA3 | TLR9 | NOS2 | P2RX7 | LTA4H | MIF | DELEC1 | G2064 | IFNG | PRKN | GSTM1 | CCDC122 | ADGB-DT | NEBL | GIT2 | MARCO | MICA | APOE | STXBP5 | TUT4 | LOC102723878 | ZMIZ1 | ODAD3

疾病靶点研报
Leprosy

Note: If you'd like to get a target analysis report for Leprosy, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Leprosy at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Arrhythmogenic Right Ventricular Cardiomyopathy | Myasthenia Gravis | Hypocalcemia | Hepatitis | Early Infantile Epileptic Encephalopathy 1 | Pyruvate Carboxylase Deficiency Disease | Thyroid Dyshormonogenesis | Diffuse Intrinsic Pontine Glioma | Corneal Dystrophies, Hereditary | Sarcoma, Alveolar Soft Part | Gilbert Syndrome | Hepatic Steatosis | Anorchia | Hepatitis, Chronic | Mixed Connective Tissue Disease | Myoclonus-dystonia Syndrome | Herpes Simplex Dermatitis | Metaphyseal Chondrodysplasia, Schmid Type | Early Infantile Epileptic Encephalopathy 13 | Superficial Spreading Melanoma | Enterocolitis, Necrotizing | Generalized Epilepsy And Paroxysmal Dyskinesia | Neurocutaneous Syndromes | Familial Hypobetalipoproteinemia | Warsaw Breakage Syndrome | Paraplegia | Vitreoretinopathy, Proliferative | Blastoma, Pleuropulmonary | ADNP Syndrome | Ligneous Conjunctivitis | Cushing Syndrome | Congenital Hemolytic Anemia | Skin Papilloma | Thrombophilia | Insulinoma | Ocular Surface Squamous Neoplasia | Netherton Syndrome | Infertility, Male | Constipation | Retinal Detachment | Spondylolisthesis | NDH Syndrome | Kallmann Syndrome | Rubeosis Iridis | Spinocerebellar Ataxia Type 13 | Craniolenticulosutural Dysplasia | Autoimmune Polyendocrinopathy Syndrome Type I | Myopathy | Pontocerebellar Hypoplasia Type 7 | Trismus-pseudocamptodactyly Syndrome | Congestive Heart Failure | Robinow Syndrome | Melanoma, Malignant | Erythromelalgia | Endophthalmitis | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Otitis Media | Intracerebral Hemorrhage | Chromosome 9q34.3 Deletion Syndrome | Acral Lentiginous Melanoma | Hereditary Hemorrhagic Telangiectasia | Coloboma | Tinea | Episodic Ataxia Type 2 | Familial Partial Lipodystrophy | Charcot-Marie-Tooth Disease Type 4E | Congenital Mirror Movements | Becker Muscular Dystrophy | Primary Erythromelalgia | Jalili Syndrome | Osteogenesis Imperfecta Type V | DNA Ligase IV Deficiency | Progressive Familial Intrahepatic Cholestasis Type 2 | Nephrocalcinosis | Guanidinoacetate Methyltransferase Deficiency | Johanson-Blizzard Syndrome | Coma | Genitopatellar Syndrome | Viral Meningitis | Pearson Syndrome | Sarcoma, Ewing | Crigler-Najjar Syndrome | Bladder Exstrophy | Glomerulonephritis, Membranoproliferative | Sialoadenitis | Urethritis | Hypercholesterolemia, Familial | Congenital Diaphragmatic Hernia | Leiomyoma | Coronary Artery Disease | Waardenburg Syndrome Type 2A | Facioscapulohumeral Muscular Dystrophy | Chronic Myeloid Leukemia | Meningitis | Chronic Inflammatory Demyelinating Polyneuropathy | Kohlschutter-Tonz Syndrome | Sleep Apnea | Idiopathic Pulmonary Fibrosis | Blepharospasm | Paraganglioma, Carotid Body | Familial Male-limited Precocious Puberty | Fibrosis | Thin Basement Membrane Disease | Binge Eating Disorder | Dyslipidemia | Diffuse Mesangial Sclerosis | Thalassemia | D-2-Hydroxyglutaric Aciduria | Dystonia | Glycogen Storage Disease Type 3 | Danon Disease | Glaucomatocyclitic Crisis | Epidermal Nevus Syndrome | Hypertension, Renal | Exocrine Pancreatic Insufficiency | Empyema | Pilomatrix Carcinoma | Palsy, Cerebral | Meconium Ileus | 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Spinocerebellar Ataxia Type 16 | Campomelic Dysplasia | Anti-glomerular Basement Membrane Disease | Gout | Alkaptonuria | Behcet's Disease | Lattice Corneal Dystrophy Type 1 | Neurodermatitis | Systemic Mastocytosis | Mitochondrial Disease | Proximal Symphalangism | Hyperlipidemia Type V | Pineoblastoma | Huntington's Disease-like 2 | Charcot-Marie-Tooth Disease Type 3 | Pulverulent Zonular Cataract | Takayasu's Arteritis | Goldenhar Syndrome | Fowler's Syndrome | Primary Familial Brain Calcification | Transthyretin-related Amyloidosis | Autonomic Nervous System Disorders | Usher Syndrome | Lysosomal Acid Lipase Deficiency | Granuloma Annulare | Dysfibrinogenemia | Cystinuria | Colitis, Collagenous | Lennox-Gastaut Syndrome | Chylomicron Retention Disease | Papulopustular Rosacea | Alveolar Capillary Dysplasia | Stroke, Ischemic | Low Phospholipid Associated Cholelithiasis | Moyamoya Disease | Hodgkin Lymphoma | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Primary Biliary Cholangitis | Blue Nevus | Charcot-Marie-Tooth Disease, Type 2 | Congenital Myasthenic Syndrome | Neuromuscular Disorders | Epiphyseal Chondrodysplasia, Miura Type | Inflammatory Bowel Disease | Trichorhinophalangeal Syndrome | Pyloric Stenosis, Infantile Hypertrophic | Tendinopathy | Pontocerebellar Hypoplasia Type 2 | Microphthalmia | Sarcoma, Endometrial Stromal | Hypercholesterolemia | Birt-Hogg-Dube Syndrome | L-2-Hydroxyglutaric Aciduria | Metatropic Dysplasia | Scapuloperoneal Spinal Muscular Atrophy | Crisponi Syndrome | Communication Disorders | Cardiac Sarcoidosis | Hypertensive Retinopathy | Congenital Dyserythropoietic Anemia Type 4 | Myasthenia | Mycosis Fungoides | Central Retinal Artery Occlusion | Ichthyosis Hystrix, Curth-Macklin Type | Homocystinuria | Disseminated Superficial Actinic Porokeratosis | Hyperparathyroidism | Sertoli Cell-only Syndrome | DiGeorge Syndrome | Shprintzen-Goldberg Syndrome | Spondyloperipheral Dysplasia | Distal Myopathy | Trichothiodystrophy | B-cell Prolymphocytic Leukemia | Spinocerebellar Ataxia Type 42 | N-acetylglutamate Synthase Deficiency | Kidney Stones | Imerslund-Grasbeck Syndrome | Hyperlipidemia | Angiosarcoma | Crouzon Syndrome With Acanthosis Nigricans | DRESS Syndrome | Cockayne Syndrome | Low Tension Glaucoma | Ectrodactyly | Macular Corneal Dystrophy Type 1 | Ocular Albinism Type 1 | Muckle-Wells Syndrome | 3-hydroxy-3-methylglutaryl-CoA Synthase Deficiency | Tuberculous Meningitis | Oculocutaneous Albinism Type 4 | Nicolaides-Baraitser Syndrome | Saul-Wilson Syndrome | Spinocerebellar Ataxia Type 38 | Common Variable Immunodeficiency | Cataplexy | ACTH-independent Macronodular Adrenal Hyperplasia | Autonomic Neuropathy | Coronary Restenosis | Mitochondrial DNA Depletion Syndrome 13 | Charcot-Marie-Tooth Disease, Type 2A | Epidermolysis Bullosa Dystrophica | Overactive Bladder | Richter's Syndrome | Heroin Dependence | Membranous Nephropathy | Metachondromatosis | Gliosarcoma | CEDNIK Syndrome | Pfeiffer Syndrome | Pneumoconiosis | Creatine Deficiency Syndrome Due To AGAT Deficiency | Fibrillation, Atrial | Progressive Encephalopathy-optic Atrophy Syndrome | Measles | Potocki-Shaffer Syndrome | Rash | Fragile X Syndrome | Keloid | Non-proliferative Diabetic Retinopathy | Schizencephaly | Myocarditis | Cyclic Vomiting Syndrome | Myopia | GM2-gangliosidosis AB Variant | Tetanus | Acute Motor Axonal Neuropathy | Primary Progressive Aphasia | Barrett Esophagus | Pycnodysostosis | Albinism | Carpal Tunnel Syndrome | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | Bipolar Disorder | Bronchitis, Chronic | Spinocerebellar Ataxia Type 10 | Autosomal Recessive Spastic Paraplegia Type 35 | Wiedemann-Steiner Syndrome | Fraser Syndrome | Neuromyotonia | Pontocerebellar Hypoplasia | Combined Pituitary Hormone Deficiency | Meesmann Corneal Dystrophy | Noonan Syndrome-like Disorder With Loose Anagen Hair | Hereditary Mixed Polyposis Syndrome | Tatton-Brown-Rahman Syndrome | Glaucoma | Aceruloplasminemia | Pneumonia, Bacterial | Colitis | Torticollis | Carcinoma, Merkel Cell | Eczema | Glomerulonephritis | CREST Syndrome | Dysthymia | Deafness, Dystonia, And Cerebral Hypomyelination | REM Sleep Behavior Disorder | Multicystic Renal Dysplasia | Apraxia | Colitis, Lymphocytic | Tyrosinemia Type 2 | Acromesomelic Dysplasia | Tylosis With Esophageal Cancer | Hypopituitarism | Charcot-Marie-Tooth Disease Type 2D | Nephritis, Interstitial | Alpha-thalassemia Myelodysplasia Syndrome | Adenocarcinoma | Aphasia | Relapsing Polychondritis | Mitochondrial DNA Depletion Syndrome | Thalassemia, Beta | Noonan Syndrome | Hereditary Sensory Neuropathy Type 1 | Echinococcosis | Small Lymphocytic Lymphoma | Budd-Chiari Syndrome | Actinomycetoma | Familial Hypertrophic Cardiomyopathy | Cervical Dystonia | Esthesioneuroblastoma | Diabetes Type 1 | Polycystic Ovary Syndrome | Angiosarcoma Of The Breast | Eosinophilic Asthma | Diamond-Blackfan Anemia | Benign Familial Neonatal Convulsions | Lymphedema | Epilepsy, Generalized | Esophageal Adenocarcinoma | Pancytopenia | Biotinidase Deficiency | Liver Failure | Urea Cycle Disorder | Corneal Dystrophy | Carcinoid Tumor | Infantile Neuroaxonal Dystrophy | 17-beta-hydroxysteroid Dehydrogenase X Deficiency | Lamellar Ichthyosis | Long-chain 3-hydroxyacyl-coenzyme A Dehydrogenase Deficiency | Cerebrotendinous Xanthomatosis | VACTERL/VATER Association | Persistent Truncus Arteriosus | Uveitis | Non-bullous Congenital Ichthyosiform Erythroderma | Lipodystrophy | Wolff-Parkinson-White Syndrome | Kernicterus | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Gerstmann-Straussler-Scheinker Syndrome | GNE Myopathy | Vaginitis | Smith-Magenis Syndrome | Basal Ganglia Disease | Dengue Shock Syndrome | Diverticulitis | Localized Scleroderma | Holoprosencephaly | Patent Foramen Ovale | Congenital Heart Block | Seminoma | Fahr Disease | Osteonecrosis | Intestinal Obstruction | Bronchitis | Graves Disease | Cardiospondylocarpofacial Syndrome | Schindler Disease | Paroxysmal Kinesigenic Dyskinesia | Rhabdomyosarcoma, Alveolar | Chylothorax, Congenital | Hypopigmentation | Intestinal Hypomagnesemia 1 | Sezary Syndrome | Pseudomyxoma Peritonei | Hereditary Xerocytosis | Coenzyme Q10 Deficiency | Cardiomyopathy, Hypertrophic | Wiskott-Aldrich Syndrome | Galactosemia | Fetal And Neonatal Alloimmune Thrombocytopenia | Chediak-Higashi Syndrome | Conjunctivitis | Sick Sinus Syndrome 1 | Lymphoma | Aneurysm, Thoracic Aortic | Thanatophoric Dysplasia Type 1 | Takenouchi-Kosaki Syndrome | Currarino Syndrome | Blastomycosis | Congenital Dyserythropoietic Anemia | Hemangioblastoma | Waardenburg Syndrome Type 2 | Glycogen Storage Disease Type 1 | Giant Cell Glioblastoma | Crohn's Disease | Bardet-Biedl Syndrome | Esophageal Carcinoma | Subcortical Band Heterotopia | Metabolic Syndrome | Raine Syndrome | Hypertension, Portal | Scoliosis | Amyotrophic Lateral Sclerosis | Cholecystitis | Loeys-Dietz Syndrome Type 4 | Amelogenesis Imperfecta | Cabezas Syndrome | Osteomalacia | Fibrosarcoma | Neurocutaneous Melanocytosis | Omenn Syndrome | Chronic Periodontitis | Presbyopia | Periventricular Nodular Heterotopia | Glycogen Storage Disease Type 4 | Myelitis | Histoplasmosis | Hemochromatosis Type 1