Neuroblastoma

About the Disease
Neuroblastoma, also known as nb, is related to differentiating neuroblastoma and glioma, and has symptoms including back pain, headache and pain. An important gene associated with Neuroblastoma is ALK (ALK Receptor Tyrosine Kinase). The drugs Nicotine and Miconazole have been mentioned in the context of this disorder. Affiliated tissues include adrenal gland, bone marrow and spinal cord, and related phenotypes are neoplasm of the nervous system and elevated urinary catecholamines

Common Targets
TGFBR2 | CD19 | MED12 | APEH | G238 | NCOR1 | KDM6A | FUBP1 | APC | RASSF1 | MYNN | ADCY7 | SMARCC1 | SPEN | UGT1A10 | G6714 | MST1R | NTRK2 | CRBN | KDR | TPM3 | RPTOR | STN1 | G472 | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | SEMA5A | AURKA | CCN1 | Protein Phosphatase 2A | G1956 | FANCD2 | ABL1 | HDAC10 | PTGES | G3845 | PLXNA3 | MEGF10 | JAK2 | EMBP1 | SOCS1 | ARID1B | NOTCH3 | ARHGEF37 | MAGEA4 | MDK | SFN | KIAA1143 | THBS1 | CCR6 | SSTR2 | PLXNB2 | G3569 | UGT1A8 | ZDHHC22 | CSK | DDX4 | CDK2 | HDAC8 | CAVIN3 | NFATC1 | G7015 | HDAC6 | CTC1 | SMARCA2 | RARA | SCNN1A | Integrin alphavbeta3 (vitronectin) receptor | FAT4 | HDAC2 | HOXA9 | SEMA3E | MIR34A | NCAM1 | HIF1A | NKX2-1 | MEF2B | POU2F2 | KMT2C | ATRX | G1/S-specific cyclin-E (nonspecified subtype) | ELANE | TRRAP | SPAG16 | TGFB1 | NPM1 | RSRC1 | IL2RA | CDK6 | ZNF502 | NRAS | Protein Kinase B (PKB/Akt) (nonspecified subtype) | AURKB | LIN28B | NF-kappaB (NFkB) | G7099 | Phosphatidylinositol 3-kinase (PI3K) (nonspecified subtype) | DUSP12 | UGT1A7 | RUNX3 | EML4 | BRD2 | PRDM2 | ZSCAN10 | AMER1 | G842 | SEMA6C | KIF15 | CACNA1G | CASR | mTOR complex 1 | MIR34B | ARID2 | CDK5 | CD3 Complex (T Cell Receptor Complex) | TP73 | SDHB | PLXNA1 | TOP1 | EMP3 | MYOD1 | CDK4 | KIT | TENM1 | G29126 | MOSPD2 | SLC6A2 | DLG2 | HDAC11 | CDK9/Cyclin T1 | HACE1 | DDR2 | REL | BRCA2 | TIAM1 | DRD2 | FGFR3 | BRD4 | NR1I2 | GRM7 | PIK3CD | NKX3-1 | CHD7 | ROS1 | FACT complex | DNA Topoisomerase II (nonspecified subtype) | G673 | HDAC3 | G5595 | CD44 | CDK9 | HSD11B1 | NSD1 | GCLC | MIR34C | CYP24A1 | NTRK3 | Pim Kinase (nonspecified subtype) | G1029 | PDGFRB | UGT1A6 | UGT1A9 | BLM | COL1A2 | IL1R1 | CSMD1 | SLC19A1 | HDAC1 | PTPN1 | L1CAM | FCGR3A | MAGI3 | CCNT1 | TLE2 | FZD5 | ZNF501 | G4609 | CASP8 | ACVR1 | LHX9 | NTRK1 | MEGF8 | GSK3B | SMARCA4 | HLA-A | Retinoid acid receptor (nonspecified subtype) | SMARCD3 | FDPS | DCX (DDB1-CUL4-X-box) E3 protein ligase complex | MS4A1 | CXCL12 | G2475 | NTN1 | FOLH1 | CDH2 | CALCRL | mTOR complex 2 | G3480 | HSD17B12 | EPHB6 | GPC2 | FLT4 | NR4A3 | SLC16A5 | HOXB5 | ND4 | IKZF3 | VPS4B | G2033 | PTPRB | KDM1A | TRIOBP | Mitogen-Activated Protein Kinase (nonspecified subtype) | NBAS | RARB | ZBTB46 | G836 | IGF2BP1 | FGFR1 | RORB | G4318 | FASN | FLT1 | ROR1 | CDK2/Cyclin A | DDX1 | CCNE1 | NR3C1 | LOC105376536 | RAF1 | PIN1 | DIS3 | CLEC12B | FGFR4 | CLPP | G196 | G7157 | INHBE | IL31RA | DDR1 | RB1 | FCGR2A | DUSP23 | BRD3 | G4193 | LOC105372327 | FASLG | ACYP2 | PBRM1 | PPP3CB | TMEM42 | DHRS3 | CDK2/Cyclin E | LIPE | Focal Adhesion Kinases (FAK) (nonspecified subtype) | PHOX2B | LMO1 | Arginase (nonspecified subtype) | Tubulin | G3082 | RUNX1 | MMP20-AS1 | Cyclin A (nonspecified subtype) | NEFL | SLIT1 | G4233 | ND5 | NOTCH2 | FCGR3B | KRT19 | CTLA4 | CD47 | ATF5 | CCR5 | PIK3CA | MYCN | MMP20 | LAMC1-AS1 | ABCC1 | KMT2D | BARD1 | RARG | ZPBP2 | DAXX | PTPN11 | CREBBP | G7124 | LOC105377056 | BIRC5 | DHFR | CPZ | GALNT14 | FLT3 | DRD3 | MTHFR | RET | ARID1A | VAV3 | CD276 | CASC15 | Proteasome Complex | PTGER2 | TOP2A | HOTAIR | RASSF2 | RASSF5 | FANCM | IGF2 | ODC1 | G5243 | MAGI2 | TGFBI

Note: If you'd like to get a target analysis report for Neuroblastoma, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Neuroblastoma at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

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