Disease

Vasculitis

About the Disease
Vasculitis, also known as autoimmune vasculitis, is related to hypersensitivity vasculitis and churg-strauss syndrome, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Vasculitis is PRTN3 (Proteinase 3), and among its related pathways/superpathways are Cytokine Signaling in Immune system and Innate Immune System. The drugs Cyclophosphamide and Alemtuzumab have been mentioned in the context of this disorder. Affiliated tissues include neutrophil, lung and heart, and related phenotypes are immune system and hematopoietic system

Common Targets
STAT6 | NOS3 | DNASE1L3 | F2 | DHODH | MOCOS | NOTCH4 | IL34 | MS4A1 | Platelet-Derived Growth Factor Receptor (nonspecified subtype) | IFNG | ITK | ADA | FAAH | JAK3 | Adenosine deaminase (nonspecified subtype) | CRBN | F5 | C3AR1 | Serine protease (nonspecified subtype) | PTPN11 | LYN | GPR84 | PDE2A | G596 | SFTPD | STING1 | C5AR1 | MTHFR | MPO | LTC4S | TREX1 | AOC3 | LGALS1 | G7124 | NR3C1 | FCER1A | LRRK2 | G3569 | PIK3CD | NR2F6 | CGAS | EPHX2 | KCNA3 | MALT1 | IL1B | PADI4

疾病靶点研报
Vasculitis

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