Marfan Syndrome

About the Disease
Marfan Syndrome, also known as mfs, is related to neonatal marfan syndrome and loeys-dietz syndrome 2. An important gene associated with Marfan Syndrome is FBN1 (Fibrillin 1), and among its related pathways/superpathways are ERK Signaling and Signal Transduction. The drugs Perindopril and Verapamil have been mentioned in the context of this disorder. Affiliated tissues include heart, spinal cord and eye, and related phenotypes are pectus carinatum and pes planus

Common Targets
ADAMTSL4 | TGFBR1 | ENG | MYH11 | G3725 | FBN2 | AGTR1 | PHEX | beta-Adrenoceptor (nonspecified subtype) | COL5A2 | SLC2A10 | Transforming growth factor beta (nonspecified subtype) | USH2A | ELN | MYLK | SMAD3 | CDK8 | ACE | COL11A1 | Angiotensin receptor (AT) (nonspecified subtype) | TGFBR2 | FLNB | MAS1 | CRYBB3 | TGFB3 | PRKG1 | MTHFR | ATP1A2 | SOS1 | ACTA2 | COL3A1 | FBN1 | SKI | G4851 | AGT | GBA1

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