Marfan Syndrome

About the Disease
Marfan Syndrome, also known as mfs, is related to neonatal marfan syndrome and loeys-dietz syndrome 2. An important gene associated with Marfan Syndrome is FBN1 (Fibrillin 1), and among its related pathways/superpathways are ERK Signaling and Signal Transduction. The drugs Perindopril and Verapamil have been mentioned in the context of this disorder. Affiliated tissues include heart, spinal cord and eye, and related phenotypes are pectus carinatum and pes planus

Common Targets
ADAMTSL4 | TGFBR1 | ENG | MYH11 | G3725 | FBN2 | AGTR1 | PHEX | beta-Adrenoceptor (nonspecified subtype) | COL5A2 | SLC2A10 | Transforming growth factor beta (nonspecified subtype) | USH2A | ELN | MYLK | SMAD3 | CDK8 | ACE | COL11A1 | Angiotensin receptor (AT) (nonspecified subtype) | TGFBR2 | FLNB | MAS1 | CRYBB3 | TGFB3 | PRKG1 | MTHFR | ATP1A2 | SOS1 | ACTA2 | COL3A1 | FBN1 | SKI | G4851 | AGT | GBA1

Note: If you'd like to get a target analysis report for Marfan Syndrome, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Marfan Syndrome at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Mucolipidosis Type II | Opisthorchiasis | Marinesco-Sjogren Syndrome | Nance-Horan Syndrome | Congenital Dyserythropoietic Anemia | Antithrombin III Deficiency | Pleurisy | Cholecystitis | Chronic Idiopathic Myelofibrosis | Impetigo | Schizoaffective Disorder | Bernard-Soulier Syndrome | Atrioventricular Septal Defect | Mitochondrial Myopathy | Chondrodysplasia Punctata 2, X-linked Dominant | Carey-Fineman-Ziter Syndrome | Hypertensive Nephropathy | Cellulitis | Aspergillosis | Bladder Exstrophy | Axenfeld-Rieger Syndrome | Adult Polyglucosan Body Disease | Fahr Disease | Cat Eye Syndrome | Hepatorenal Syndrome | Atrial Septal Defect | Necrotizing Autoimmune Myopathy | Chronic Myelomonocytic Leukemia | Lipid Storage Diseases | Hepatitis C, Chronic | Anthrax | Sarcosinemia | ADNP Syndrome | Glutaric Aciduria Type 3 | Cerebellofaciodental Syndrome | Arts Syndrome | Glycogen Storage Disease Type 0, Muscle | Muscle Wasting | Carney-Stratakis Syndrome | Gilbert Syndrome | Juvenile Polyposis | Mitochondrial DNA Depletion Syndrome, Myopathic Form | Splenomegaly | Kleine-Levin Syndrome | Leri-Weill Dyschondrosteosis | Agammaglobulinemia | Marfan Syndrome | Oculocutaneous Albinism Type 4 | Diabetes | Epidermolysis Bullosa | Leishmaniasis, Visceral | Odonto-onycho-dermal Dysplasia | Bartter Syndrome | Anti-NMDA Receptor Encephalitis | Sotos Syndrome | Neurofibromatosis Type 1 | Dementia | Acquired Partial Lipodystrophy | Leukemia-lymphoma, Adult T-cell | Agranulocytosis | Holt-Oram Syndrome | Myeloid Leukemia | Hereditary Coproporphyria | Tracheal Disorders | Paraganglioma | Alazami Syndrome | Rhabdomyosarcoma, Alveolar | Pierson Syndrome | Photosensitivity | Oligospermia | Kearns-Sayre Syndrome | Polycystic Kidney, Autosomal Dominant | Yellow Fever | High Molecular Weight Kininogen Deficiency | Gitelman Syndrome | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Rheumatoid Arthritis | Heart Block | Leukocyte Adhesion Deficiency | Alveolar Capillary Dysplasia | Familial Hypertrophic Cardiomyopathy | Pfeiffer Syndrome | Tangier Disease | Ocular Surface Squamous Neoplasia | Cardiospondylocarpofacial Syndrome | Erysipelas | Combined Malonic And Methylmalonic Acidemia | Conduct Disorder | Discoid Lupus Erythematosus | Encephalopathy, Ethylmalonic | Acute Coronary Syndrome | Pulmonary Alveolar Proteinosis | Noonan Syndrome | Delayed Sleep Phase Syndrome | Mast Cell Leukemia | Lichen Planus | Acute Myeloid Leukemia | Intestinal Hypomagnesemia 1 | Ataxia-ocular Apraxia 2 | Systemic Mastocytosis | Babesiosis | Bronchitis | Panic Disorder | Hemorrhage | Mucormycosis | Mastitis | Ventricular Septal Defect | Amelogenesis Imperfecta | Fucosidosis | Anterior Segment Dysgenesis | Stroke, Ischemic | Tay-Sachs Disease | Sleep Disorder | ICF Syndrome | Infertility | 3-hydroxy-3-methylglutaric Aciduria | Charcot-Marie-Tooth Disease, Type 1A | Lipodystrophy | Guttate Psoriasis | Platyspondylic Lethal Skeletal Dysplasia, Torrance Type | Rhabdomyosarcoma | Mucolipidosis | Temporal Lobe Epilepsy | Cramp Fasciculation Syndrome | Sleep Apnea, Obstructive | Retinal Dystrophy, Early-onset Severe | Angiodysplasia | Withdrawal Syndrome | Oculocutaneous Albinism Type 2 | Pearson Syndrome | Spondylocarpotarsal Synostosis Syndrome | Purpura | Porphyria, Variegate | Poretti-Boltshauser Syndrome | Loeys-Dietz Syndrome | Budd-Chiari Syndrome | Prostatitis | B-cell Prolymphocytic Leukemia | Trichuriasis | Neurotoxicity | Multiple Sclerosis | Arthrogryposis | Cole-Carpenter Syndrome | Myelofibrosis | Imerslund-Grasbeck Syndrome | Congenital Nystagmus | Cancer, Breast | Hypoproteinemia, Hypercatabolic | Hypersensitivity Pneumonitis | Vitamin B12 Deficiency | Steel Syndrome | Glycogen Storage Disease Type 6 | Johanson-Blizzard Syndrome | Autoimmune Autonomic Ganglionopathy | Cri-du-chat Syndrome | Heroin Dependence | Lennox-Gastaut Syndrome | Weill-Marchesani Syndrome | Supravalvular Aortic Stenosis | Hypertension, Essential | Chondroma | Autism | Majeed Syndrome | Myositis, Focal | Hyperinsulinism-hyperammonemia Syndrome | Feingold Syndrome | Glycogen Storage Disease | Sclerosteosis | Meckel-Gruber Syndrome | Extramammary Paget's Disease | Papillorenal Syndrome | Potocki-Shaffer Syndrome | Creutzfeldt-Jakob Disease | Frank-ter Haar Syndrome | T-cell Prolymphocytic Leukemia | Infectious Diarrhea | Ameloblastoma | Protein S Deficiency | Stargardt Disease | Prurigo Nodularis | Kidney Stones | Anemia | Harlequin Ichthyosis | Melanoma | Varicocele | Basal Cell Nevus Syndrome | Macrodactyly | Diabetic Macular Edema | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | PASLI Disease | Microphthalmia, Syndromic 7 | Joubert Syndrome | Hyper IgE Syndrome | Multisystemic Smooth Muscle Dysfunction Syndrome | Epidermal Nevus Syndrome | Connective Tissue Disorders | Pneumonia, Mycoplasma | Hypertension, Renal | TARP Syndrome | Postpoliomyelitis Syndrome | Major Depression | Tinea Versicolor | Carbohydrate Metabolism Disorders | Esotropia | Carcinoma, Merkel Cell | Lymphangioma | Ichthyosis | Brachial Plexus Neuropathy | Thrombocytopenia | Rubinstein-Taybi Syndrome | Actinomycetoma | Chronic Mucocutaneous Candidiasis | Hypertension, Portal | Scabies | Cutaneous Lupus Erythematosus | Micropenis | Gastritis, Atrophic | Jawad Syndrome | Nanophthalmos | Myotonic Disorders | Spitz Nevus | Familial Isolated Hyperparathyroidism | Biotinidase Deficiency | Osteopetrosis | AIDS Dementia Complex | Nijmegen Breakage Syndrome | Neurofibromatosis | Urofacial Syndrome | Focal Facial Dermal Dysplasia | Thyroid Hormone Resistance | Pendred Syndrome | Epidermolysis Bullosa Dystrophica | Still Disease | Blue Rubber Bleb Nevus Syndrome | Distal Spinal Muscular Atrophy | Spina Bifida | Pupil Disorders | Glanzmann Thrombasthenia | Platelet Disorders | Hyperkalemic Periodic Paralysis | Blepharophimosis Syndrome | Polycythemia Vera | Rosacea | Pemphigoid | Pantothenate Kinase-associated Neurodegeneration | Vasculitis | Zygomycosis | Peters-plus Syndrome | Retinitis Pigmentosa | Hepatitis D | Hypotension, Orthostatic | Prader-Willi Syndrome | Peutz-Jeghers Syndrome | Congenital Diaphragmatic Hernia | Osteomalacia | Addison Disease | Meesmann Corneal Dystrophy | Hidradenitis | Congenital Central Hypoventilation Syndrome | Stiff-man Syndrome | Congenital Lipoid Adrenal Hyperplasia | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Intermittent Claudication | Farber Disease | Carbamoyl Phosphate Synthetase I Deficiency | Liebenberg Syndrome | Blood Protein Disorders | Tremor | Glycogen Storage Disease Type 1 | Frontometaphyseal Dysplasia | Retinal Degeneration | Episodic Ataxia Type 1 | Encephalocele | Obesity | Vitelliform Macular Dystrophy | Hypereosinophilic Syndrome | Trichotillomania | Apert Syndrome | Non-small Cell Lung Cancer | Angiosarcoma | Osteogenesis Imperfecta Type VI | Juvenile Myelomonocytic Leukemia | AIDS | Spermatocele | Hypotonia-cystinuria Syndrome | C3 Glomerulonephritis | Sarcoidosis | Idiopathic Pulmonary Fibrosis | Dystonia Musculorum Deformans | Paracoccidioidomycosis | Schamberg Disease | Central Core Disease | Asplenia | Venous Insufficiency | Deafness, Dystonia, And Cerebral Hypomyelination | Schnyder Crystalline Corneal Dystrophy | Hermansky-Pudlak Syndrome | Neural Tube Defect | Keratoconjunctivitis | Anovulation | DRESS Syndrome | Infantile Neuroaxonal Dystrophy | Restrictive Dermopathy | Prolymphocytic Leukemia | T-cell Leukemia | Chediak-Higashi Syndrome | Okihiro Syndrome | Spinocerebellar Ataxia Type 12 | Metaphyseal Chondrodysplasia, Schmid Type | Polycystic Ovary Syndrome | Hypoplastic Left Heart Syndrome | Primrose Syndrome | Hereditary Sensory Neuropathy Type 1 | Cancer, Bladder | Spinocerebellar Ataxia Type 31 | NGLY1 Deficiency | Psoriasis | Mixed Connective Tissue Disease | Partington Syndrome | Leri Pleonosteosis | Influenza | Spondyloarthritis | Cirrhosis | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Basal Ganglia Disease, Biotin-responsive | Spinocerebellar Ataxia Type 28 | Pierre Robin Syndrome | Pyruvate Dehydrogenase Deficiency | Glaucoma, Congenital | Glutaric Aciduria Type 1 | Erythrokeratodermia Variabilis | Dementia, Vascular | Traboulsi Syndrome | Colorectal Adenoma | Niemann-Pick Disease, Type B | Angiosarcoma Of The Breast | Lymphopenia | Eosinophilia | Varices | Cornelia De Lange Syndrome | Retinal Dystrophy | Acne | VEXAS Syndrome | Arteriovenous Malformations | Disseminated Superficial Actinic Porokeratosis | Lafora Disease | Transcobalamin Deficiency | Hypohidrotic Ectodermal Dysplasia | Papillon-Lefevre Syndrome | Congenital Nephrotic Syndrome | Nephrocalcinosis | Peritonitis | Tonsillitis | Retinitis | Pyruvate Carboxylase Deficiency Disease | Lattice Corneal Dystrophy Type 1 | Arterial Tortuosity Syndrome | Colitis, Collagenous | Cutaneous Angiosarcoma | Pancreatitis, Chronic | Evans Syndrome | Renal Medullary Carcinoma | Hypotrichosis | Renal Hypomagnesemia 3 | Menkes Disease | POEMS Syndrome | Optic Nerve Hypoplasia, Bilateral | 3-methylglutaconic Aciduria | Porencephaly | Persistent Hyperplastic Primary Vitreous | Primary Progressive Aphasia | Esophageal Carcinoma | Premenstrual Syndrome | Diabetes Insipidus, Neurogenic | Phosphoglycerate Dehydrogenase Deficiency | Arthritis | Pelvic Inflammatory Disease | Dysgerminoma | Seminoma | Osteogenesis Imperfecta Type II | Graves Disease | Fetal And Neonatal Alloimmune Thrombocytopenia | Cancer, Lung | Acute Lymphocytic Leukemia | Aldosterone Deficiency | Hypertension | Cholera | Primary Hyperoxaluria Type 1 | Genitopatellar Syndrome | KBG Syndrome | Adenoma, Pleomorphic | Anxiety Disorders | Vascular Calcification | Glomerulonephritis | Spinal Muscular Atrophy Type 2 | Granuloma Annulare | Wolff-Parkinson-White Syndrome | Anorchia | Medulloblastoma | Hypertriglyceridemia