Thyroid Hormone Resistance

About the Disease
Thyroid Hormone Resistance, Generalized, Autosomal Dominant, also known as thyroid hormone resistance syndrome, is related to hypothyroidism, congenital, nongoitrous, 2 and tsh producing pituitary tumor. An important gene associated with Thyroid Hormone Resistance, Generalized, Autosomal Dominant is THRB (Thyroid Hormone Receptor Beta), and among its related pathways/superpathways are Angiopoietin-like protein 8 regulatory pathway and Nuclear receptors. Affiliated tissues include thyroid, pituitary and bone, and related phenotypes are delayed speech and language development and attention deficit hyperactivity disorder

Common Targets
THRB | THRA

Note: If you'd like to get a target analysis report for Thyroid Hormone Resistance, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Thyroid Hormone Resistance at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Hepatitis B, Chronic | Leukoencephalopathy, Progressive Multifocal | Alopecia | Asthma, Exercise-induced | Sjogren Syndrome | Epidermolytic Ichthyosis, Annular | Necrotizing Autoimmune Myopathy | Jacobsen Syndrome | Leishmaniasis, Visceral | Sialoadenitis | Aphasia | Aneurysm, Abdominal Aortic | Anti-NMDA Receptor Encephalitis | Neutropenia | Danon Disease | Macular Corneal Dystrophy Type 1 | Glycogen Storage Disease Type 5 | Spinocerebellar Ataxia Type 23 | Mabry Syndrome | Spinocerebellar Ataxia Type 38 | Duchenne Muscular Dystrophy | Spinocerebellar Ataxia Type 10 | Dengue Hemorrhagic Fever | Raine Syndrome | Synpolydactyly | Common Cold | Sick Sinus Syndrome 1 | Waardenburg Syndrome Type 2A | Glycogen Storage Disease Type 1 | Japanese Encephalitis | Cleidocranial Dysplasia | Leukoplakia, Oral | Giant Cell Glioblastoma | Retinoblastoma | Sleep Apnea | Mitochondrial Myopathy | Nephropathy | Familial Thoracic Aortic Aneurysm | Rift Valley Fever | Dystonia | Genee-Wiedemann Syndrome | Narcolepsy | Lafora Disease | Colon Adenoma | Non-proliferative Diabetic Retinopathy | Progressive Myoclonic Epilepsy | Pneumonia, Mycoplasma | Adenosine Deaminase Deficiency | Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy | Coronary Heart Disease | Nutrition Disorders | Esotropia | Chronic Myeloid Leukemia | Presbycusis | Hyperandrogenemia | Infantile Neuroaxonal Dystrophy | Prediabetes | Spinocerebellar Ataxia Type 6 | Tracheal Disorders | Tetraplegia | Reye Syndrome | Desbuquois Syndrome | Pouchitis | Hypertension, Renovascular | 3-hydroxy-3-methylglutaric Aciduria | Hermansky-Pudlak Syndrome | Myocarditis | Glioblastoma | Colitis, Collagenous | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Dysferlinopathy | Juvenile Myelomonocytic Leukemia | Necrobiosis Lipoidica | Sarcoma | Vestibular Disease | Osteogenesis Imperfecta Type VI | Progressive Encephalopathy-optic Atrophy Syndrome | HUPRA Syndrome | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Bietti Crystalline Dystrophy | Zellweger Syndrome | Hypotension, Orthostatic | Camptocormia | Metabolic Syndrome | Neuroectodermal Tumors, Primitive | Epidermolysis Bullosa Simplex With Mottled Pigmentation | Congenital Bile Acid Synthesis Defect | Albinism | Autosomal Recessive Congenital Ichthyosis | Congenital Adrenal Hyperplasia | Schwannoma | Cranial Nerve Disease | Spasticity | Cancer, Prostate | Prurigo Nodularis | Primary Sclerosing Cholangitis | Acne | Lymphedema | Atopy | Myasthenia Gravis | Fowler's Syndrome | Leukemia-lymphoma, Adult T-cell | Primary Hyperoxaluria | Bare Lymphocyte Syndrome | Malaria, Cerebral | Arthritis | Panic Disorder | Combined Malonic And Methylmalonic Acidemia | Bronchitis | Behcet's Disease | Ocular Surface Squamous Neoplasia | Allergic Contact Dermatitis | Meesmann Corneal Dystrophy | Cataract | Stuttering | Peripheral T-cell Lymphoma | Heart Failure | Neurocutaneous Syndromes | Mixed Connective Tissue Disease | Norrie Disease | Hyper IgE Syndrome | Retinitis Pigmentosa | Combined Deficiency Of Factor V And Factor VIII | X-linked Acrogigantism | Leber Hereditary Optic Neuropathy | Multiple Sclerosis | Wolfram Syndrome | Takenouchi-Kosaki Syndrome | Persistent Mullerian Duct Syndrome | Persistent Hyperplastic Primary Vitreous | Acrodermatitis | Osteosarcoma | Erythematotelangiectatic Rosacea | Ataxia-hypogonadism-choroidal Dystrophy Syndrome | Jaundice, Obstructive | Erdheim-Chester Disease | Pseudohypoparathyroidism Type 2 | Glycogen Storage Disease Type 9 | Contact Dermatitis | Retinal Telangiectasia | Giant Cell Arteritis | Varices | Overactive Bladder | Schaaf-Yang Syndrome | Tibial Muscular Dystrophy | Hypotonia-cystinuria Syndrome | Liver Failure, Acute Infantile | Pineoblastoma | Headache | Pemphigus Vulgaris | Amyotrophic Lateral Sclerosis-parkinsonism-dementia Complex | Dysequilibrium Syndrome | Menetrier Disease | Aplastic Anemia | Bloom Syndrome | Hyperacusis | Kawasaki Disease | Shprintzen-Goldberg Syndrome | Amish Infantile Epilepsy Syndrome | Johanson-Blizzard Syndrome | Light Chain Amyloidosis | Subacute Sclerosing Panencephalitis | Pleural Tuberculosis | Ovarian Hyperstimulation Syndrome | N-acetylglutamate Synthase Deficiency | Hypercholesterolemia, Familial | Fibrosis | Osteoporosis, Postmenopausal | Hemosiderosis | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Peters-plus Syndrome | Vitamin K Deficiency | Conduct Disorder | Duane Retraction Syndrome | Glycogen Storage Disease Type 0, Muscle | Epicondylitis | Malonyl-CoA Decarboxylase Deficiency | Pulmonary Capillary Hemangiomatosis | Gastric Atrophy | Primary Ovarian Insufficiency | Arthropathy | Hypobetalipoproteinemias | Schindler Disease | Wiskott-Aldrich Syndrome | Ophthalmia, Sympathetic | Wiedemann-Steiner Syndrome | Potocki-Shaffer Syndrome | Hypertension, Pulmonary | Thyroid Hormone Resistance | Histoplasmosis | Alzheimer Disease, Late Onset | Chronic Neutrophilic Leukemia | Systemic Mastocytosis | Usher Syndrome Type IIC | Transient Bullous Dermolysis Of The Newborn | Fontaine Progeroid Syndrome | Paronychia | Acrodermatitis Enteropathica | ADNP Syndrome | Nephronophthisis | Tuberculous Meningitis | Crigler-Najjar Syndrome | Tendinopathy | Phenylketonuria II | Centronuclear Myopathy | Erythrokeratodermia Variabilis | Schizophrenia, Paranoid | Primary Torsion Dystonia | Hepatopulmonary Syndrome | Sengers Syndrome | Scapuloperoneal Myopathy, X-linked Dominant | Gastroschisis | Meningioma | Platyspondylic Lethal Skeletal Dysplasia, Torrance Type | Congenital Stationary Night Blindness | Familial Hemiplegic Migraine | Lipoma | Esophageal Carcinoma | Parkinson Disease 6, Autosomal Recessive Early-onset | Schistosomiasis | Spinal Muscular Atrophy | Metachondromatosis | Androgen Insensitivity | Von Hippel-Lindau Disease | Glomerulonephritis | Photosensitivity | Fetal Akinesia Deformation Sequence | Glomerulonephritis, Membranoproliferative | Varicocele | PASLI Disease | Amebiasis | Macrodactyly | Hyperammonemia | Acromesomelic Dysplasia | Mumps | Carcinoma, Signet Ring Cell | Congenital Sodium Diarrhea | Glutathione Synthetase Deficiency | Cardiospondylocarpofacial Syndrome | Encephalocele | Waardenburg Syndrome Type 2 | Van Der Knaap Disease | Enterocolitis, Necrotizing | Familial Male-limited Precocious Puberty | Waardenburg Syndrome Type 1 | Leiomyosarcoma | Mast Cell Leukemia | Aplasia Cutis Congenita | Hyperhomocysteinemia | Cherubism | Deafness, Dystonia, And Cerebral Hypomyelination | Pulmonary Alveolar Proteinosis | Sezary Syndrome | Constipation | Chronic Thromboembolic Pulmonary Hypertension | Small Lymphocytic Lymphoma | Coffin-Siris Syndrome | Erythema Multiforme | Pituitary Stalk Interruption Syndrome | Hidradenitis | Eiken Syndrome | Polycythemia Vera | Sweet Syndrome | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Arthrogryposis | Cranioectodermal Dysplasia | Parvovirus B19 Infection | Thalassemia, Beta | Raynaud Phenomenon | Adenoma, Pleomorphic | Charcot-Marie-Tooth Disease, Type 1A | Cold Agglutinin Disease | Periodontitis | Hypoparathyroidism | Language Disorders | Tyrosinemia | Persistent Fetal Circulation | Dupuytren Disease | Leukoplakia | Glycogen Storage Disease Type 4 | Vogt-Koyanagi-Harada Syndrome | Familial Dysautonomia | Glycogen Storage Disease Type 1b | Riboflavin Transporter Deficiency Neuronopathy | Peripheral Neuropathy | Hartsfield Syndrome | Chronic Mucocutaneous Candidiasis | Hyperphenylalaninemia | Herpes Simplex Dermatitis | Blepharoconjunctivitis | Cervicitis | Bartter Syndrome | Babesiosis | Ichthyosis | Chiari Malformation Type I | Microtia | Encephalitis, Tick-borne | Chromosome 8q21.11 Deletion Syndrome | Acute Chest Syndrome | Cramp Fasciculation Syndrome | Meniere's Disease | Hemangioma | DNA Ligase IV Deficiency | Hypospadias | Sporadic Inclusion Body Myositis | Fibromyalgia | Infertility, Male | T-cell Chronic Lymphocytic Leukemia | Pyelonephritis | Fibrodysplasia Ossificans Progressiva | Myocardial Infarction | Feingold Syndrome | Keratosis | Harlequin Ichthyosis | Majeed Syndrome | Thrombophlebitis | Thyroiditis, Autoimmune | DiGeorge Syndrome | Pancreatitis | Spinocerebellar Ataxia Type 21 | X-linked Sideroblastic Anemia | Cutaneous Lupus Erythematosus | Heimler Syndrome | Cholelithiasis | Autism | Rosacea | Stroke, Hemorrhagic | Hypopituitarism | Hyperparathyroidism, Primary | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Pierson Syndrome | Erythromelalgia | Preaxial Polydactyly | Pyruvate Dehydrogenase Deficiency | Malaria | Hepatitis C, Chronic | Hypokalemic Periodic Paralysis | Dyggve-Melchior-Clausen Disease | Acute Anterior Uveitis | Heart Septal Defects | Brenner Tumor | Encephalitis | Antenatal Bartter Syndrome Type 1 | Polycythemia | Gingivitis | Nevus | Oligospermia | Leukodystrophies | Pulmonary Sclerosing Hemangioma | Kohlschutter-Tonz Syndrome | Thyroiditis | Polymyositis | Otitis Externa | Chromosome 9q34.3 Deletion Syndrome | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Stroke, Ischemic | Microcephaly, Seizures, And Developmental Delay | Multiple Sclerosis, Chronic Progressive | Corneal Dystrophies, Hereditary | Measles | Hereditary Multiple Exostoses | Peyronie's Disease | Corneal Dystrophy And Perceptive Deafness | Liebenberg Syndrome | Heterotaxy | Megaloblastic Anemia | Early Infantile Epileptic Encephalopathy 4 | Stuve-Wiedemann Syndrome | DRESS Syndrome | Aldosterone Deficiency | Milk Allergy | Familial Isolated Hyperparathyroidism | Diabetes Type 1 | Charcot-Marie-Tooth Disease Type 2D | Vitelliform Macular Dystrophy | Pituitary Disorders | Mitochondrial DNA Depletion Syndrome | Systemic Lupus Erythematosus | Cancer, Bladder | Dementia | Renpenning Syndrome | Silicosis | Hepatitis D | Seasonal Mood Disorder | Juvenile Polyposis | Pantothenate Kinase-associated Neurodegeneration | Spinocerebellar Ataxia Type 14 | Nephrosclerosis | Diffuse Intrinsic Pontine Glioma | Zimmermann-Laband Syndrome | Thyroid Dysgenesis | Hereditary Elliptocytosis | Leukocyte Adhesion Deficiency | Sclerosing Cholangitis | GLUT1 Deficiency Syndrome | Trichorhinophalangeal Syndrome | Porphyria, Variegate | Chromosome 17q21.31 Deletion Syndrome | Lesch-Nyhan Syndrome | Frontotemporal Dementia