Ocular Hypertension

About the Disease
Ocular Hypertension, also known as intraocular pressure increase, is related to open-angle glaucoma and intraocular pressure quantitative trait locus, and has symptoms including eye manifestations An important gene associated with Ocular Hypertension is MYOC (Myocilin), and among its related pathways/superpathways are Cellular responses to stimuli and Signal Transduction. The drugs Dipivefrin and Dexamethasone acetate have been mentioned in the context of this disorder. Affiliated tissues include eye, retina and endothelial, and related phenotypes are homeostasis/metabolism and nervous system

Common Targets
CYP19A1 | Proteasome Complex | ADRA2C | HSP90B1 | GPR55 | G7124 | BDKRB2 | ENPP2 | SNCA | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | KDR | PREP | PTGES | SLC18A2 | MC1R | LIMK1 | JAK2 | PTGER3 | LRRK2 | MTNR1A | G7015 | PRKCG | ADRA2B | TRPV4 | G3620 | LIMK2 | Heat shock protein 90 (nonspecified subtype) | ROCK1 | MYOC | Alpha-2 Adrenergic receptors (nonspecified subtype) | CNR2 | PPARA | Phosphatidylinositol 3-kinase (PI3K) (nonspecified subtype) | Protein kinase C (nonspecified subtype) | ADORA1 | NF-kappaB (NFkB) | CAST | SLC6A2 | LOC101929309 | CA7 | CNR1 | MTNR1B | cAMP-Dependent protein kinase (PKA) | ADRA2A | DYRK1A | Na+/K+-ATPase (nonspecified subtype) | FKBP5 | LOC105378206 | Reverse transcriptase (Telomerase) | K(ATP) Channel (nonspecified subtype) | ADORA2A | ADORA3 | beta-Adrenoceptor (nonspecified subtype) | PTGER4 | Actin (nonspecified subtype) | Vascular endothelial growth factor receptor (VEGFR) (nonspecified subtype) | FAAH | PTPRB | Platelet-Derived Growth Factor Receptor (nonspecified subtype) | TGFB2 | FASN | NQO2 | PTGER1 | AP-1 Transcription Factor Complex | TEK | SLC5A1 | SLCO2A1 | CA2 | ROCK2 | ADRB2 | alpha1-Adrenoceptor (nonspecified subtype) | SRSF3 | NR3C1 | AGTR2 | PDE5A | AGTR1 | ADRA1B | PKN2 | HTR2A | REN | LOC105375032 | PTGFR | Bradykinin receptor (nonspecified subtype) | LOC105375033 | Rho kinase (ROCK) (nonspecified subtype) | MC5R | ENOX2 | Soluble guanylyl cyclase | PTGER2 | Histone deacetylase (nonspecified subtype) | CA4

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