Autoimmune Polyendocrine Syndrome

About the Disease
Autoimmune Polyendocrine Syndrome, also known as autoimmune polyglandular failure, is related to autoimmune polyendocrine syndrome, type ii and autoimmune polyendocrine syndrome, type i, with or without reversible metaphyseal dysplasia. An important gene associated with Autoimmune Polyendocrine Syndrome is AIRE (Autoimmune Regulator), and among its related pathways/superpathways are Innate Immune System and Immune response IL-23 signaling pathway. The drugs Hydroxyurea and Racepinephrine have been mentioned in the context of this disorder. Affiliated tissues include thyroid, t cells and thymus, and related phenotypes are homeostasis/metabolism and immune system

Common Targets
FOXD3 | HLA-A | G7124 | CTLA4 | VDR | PTPN22

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