Nephropathy

About the Disease
Kidney Disease, also known as renal failure, is related to chronic kidney disease and polycystic kidney disease, and has symptoms including polyuria An important gene associated with Kidney Disease is TSC1 (TSC Complex Subunit 1), and among its related pathways/superpathways are Ciliopathies and Bardet-Biedl syndrome. The drugs Amiodarone and Nicotinamide have been mentioned in the context of this disorder. Affiliated tissues include kidney, heart and bone marrow, and related phenotypes are homeostasis/metabolism and renal/urinary system

Common Targets
SSTR2 | CFB | G1026 | MYH9 | G4780 | COL4A5 | EPHX2 | G2475 | GJA4 | C5 | STAT6 | TYR | Lipoxygenase (nonspecified subtype) | CNR1 | PPARG | PTGIR | G142 | TRPC5 | APLNR | GCK | PTGS1 | Chymotrypsin (nonspecified subtype) | ANGPTL3 | SSTR3 | MC2R | DPP4 | ARHGAP24 | SLC9A3 | ABCA1 | SOD2 | PPARD | PCSK9 | PTPN1 | XDH | G5243 | NR1H4 | VDR | G836 | SSTR4 | ADORA3 | NOS3 | MS4A1 | IL10 | CTLA4 | LMX1B | CLDN8 | CYP3A5 | ESRRA | OSBPL7 | TGFB2 | GHR | IFNG | IL1B | DGKE | NMDA receptor | GAA | AGTR1 | CCR5 | PON1 | Complement Complex | MIR146A | Proteasome Complex | AGER | APOL1 | JAK3 | APOE | AGTR2 | Hypoxia-Inducible Factor Prolyl Hydroxylase (nonspecified subtype) | COL4A3 | KLKB1 | F11 | ESRRG | SLC34A2 | F2R | Potassium Channels (nonspecified subtype) | Endothelin receptor (nonspecified subtype) | CD19 | MAFB | TGFB3 | Soluble guanylyl cyclase | HNF1B | CHRM2 | REN | AOC3 | TGFB1 | CMA1 | Phosphodiesterase (nonspecified subtype) | COQ2 | EDNRA | AMP-activated protein kinase (AMPK) | ST6GALNAC2 | G7124 | GPBAR1 | TBXAS1 | ASGR1 | CAPN10 | Asialoglycoprotein Receptor (ASGPR) (nonspecified subtype)

Note: If you'd like to get a target analysis report for Nephropathy, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Nephropathy at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Osteosarcoma | McCune-Albright Syndrome | Stromal Corneal Dystrophy | Leukemia | Dysplastic Nevus | Acute Generalized Exanthematous Pustulosis | Johanson-Blizzard Syndrome | Plasma Cell Leukemia | Hemorrhagic Disorders | VACTERL/VATER Association | Carcinoid Tumor | Tendinitis | Cardiospondylocarpofacial Syndrome | Sorsby Fundus Dystrophy | Nasodigitoacoustic Syndrome | Hyperthyroidism | Hepatic Steatosis | Benign Familial Infantile Seizures | Congenital Dysfibrinogenemia | Familial Hyperaldosteronism | Hypokalemic Periodic Paralysis | Melnick-Needles Syndrome | Pyruvate Kinase Deficiency | Hypercalciuria | Lafora Disease | Nutrition Disorders | Heterotopic Ossification | Birk-Barel Syndrome | Atrioventricular Septal Defect | Weill-Marchesani Syndrome | Autonomic Nervous System Disorders | Platelet Disorders | Dyskeratosis Congenita | Hypertelorism | Swine Influenza | Retinoblastoma | Lissencephaly 2 | Hepatopulmonary Syndrome | Mood Disorder | Uremia | Sialidosis Type I | Familial Partial Lipodystrophy | Herpes Simplex Dermatitis | Glycogen Storage Disease Type 0, Muscle | Hereditary Spherocytosis | Colitis, Lymphocytic | Alopecia Totalis | Hyperkeratosis | Anuria | Intracerebral Hemorrhage | Oculocutaneous Albinism Type 4 | Acromesomelic Dysplasia | Cancer, Skin | Muir-Torre Syndrome | Mitochondrial Disease | Anthrax | Asperger Syndrome | Chondromyxoid Fibroma | Hyperphosphatasia With Intellectual Disability Syndrome 4 | Parkinson's Disease | Osteitis | Cholestasis, Intrahepatic | Spinocerebellar Ataxia Type 38 | Diabetes Type 2 | Chronic Mucocutaneous Candidiasis | Arteriosclerosis | Enterocolitis, Necrotizing | Congenital Diaphragmatic Hernia | Dyggve-Melchior-Clausen Disease | Vitamin D Deficiency | Pulmonary Veno-occlusive Disease | Hemoglobinopathies | Meniere's Disease | Peripheral Neuropathy | Arthritis, Gouty | Eclampsia | Blood Protein Disorders | Maternally Inherited Diabetes And Deafness | Colon Adenoma | Keratoconjunctivitis | Juvenile Myelomonocytic Leukemia | Majeed Syndrome | Multifocal Motor Neuropathy | Otitis Externa | Asplenia | Lymphoma, AIDS-related | Cannabis Abuse | Fibronectin Glomerulopathy | Mucolipidosis | Myotonia | Blastomycosis | Light Chain Amyloidosis | Rothmund-Thomson Syndrome | Connective Tissue Disorders | Amyotrophic Lateral Sclerosis-parkinsonism-dementia Complex | Micropenis | Waardenburg Syndrome Type 4 | Creatine Deficiency Syndrome | Liver Diseases | Spinal Cord Diseases | Mountain Sickness | Schwannoma | Frontotemporal Dementia | Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress | Amyotrophic Lateral Sclerosis, Juvenile | Asthma, Nocturnal | Sezary Syndrome | Cold Agglutinin Disease | Hereditary Elliptocytosis | Multisystemic Smooth Muscle Dysfunction Syndrome | Osteochondrosis | Osteogenesis Imperfecta Type V | Gynecomastia | Hyperekplexia | Congenital Nystagmus | Chitayat Syndrome | Congenital Hypofibrinogenemia | Early Infantile Epileptic Encephalopathy 28 | Congenital Dyserythropoietic Anemia Type 1 | Episodic Ataxia | Cystinosis | Patent Ductus Arteriosus | Twin-to-twin Transfusion Syndrome | Pityriasis Rubra Pilaris | Best Macular Dystrophy | Cystitis | Non-epidermolytic Palmoplantar Keratoderma | SAPHO Syndrome | Multiple Sclerosis, Primary Progressive | Influenza | Keloid | IMAGe Syndrome | GATA2 Deficiency | Sensorineural Hearing Loss | Venous Insufficiency | Common Variable Immunodeficiency | Silicosis | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Neurofibromatosis Type 2 | Leukoplakia, Oral | Trimethylaminuria | Fibromyalgia | Metachondromatosis | Trichothiodystrophy | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Lichen Sclerosus | Metaphyseal Chondrodysplasia, Schmid Type | Conn Syndrome | Hypolipoproteinemia | Heart Block | Immunoproliferative Disorders | Hypothyroidism | 3-methylglutaconic Aciduria Type IV | Lipid Storage Diseases | Premenstrual Syndrome | Charcot-Marie-Tooth Disease, Type 2A | Tricho-hepato-enteric Syndrome | Fibrosis | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 1 | Combined Deficiency Of Factor V And Factor VIII | ADNP Syndrome | Craniolenticulosutural Dysplasia | Vascular Calcification | Postpartum Depression | Pouchitis | Mitochondrial Myopathy | Exocrine Pancreatic Insufficiency | Esotropia | Bladder Exstrophy | Pantothenate Kinase-associated Neurodegeneration | Seborrheic Dermatitis | Nevus | Hyperacusis | Cystitis, Interstitial | Primary Hyperoxaluria Type 3 | Familial Male-limited Precocious Puberty | Cherubism | Persistent Hyperplastic Primary Vitreous | Zellweger Syndrome | Lactose Intolerance | Congenital Absence Of Vas Deferens | Retinal Diseases | LEOPARD Syndrome | Heroin Dependence | Orotic Aciduria | Epidermolysis Bullosa Simplex With Mottled Pigmentation | Microcephalic Osteodysplastic Primordial Dwarfism, Type I | Myelofibrosis | Renpenning Syndrome | Marinesco-Sjogren Syndrome | Personality Disorders | Erysipelas | Diabetic Neuropathy | Neonatal Progeroid Syndrome | Leri Pleonosteosis | Cone Dystrophy | Beckwith-Wiedemann Syndrome | Lymphedema | Rheumatic Heart Disease | Hepatoblastoma | Aspergillosis | Congenital Dyserythropoietic Anemia Type 4 | Situs Inversus | Restless Legs Syndrome | Urofacial Syndrome | Micro Syndrome | Myotonic Disorders | Hereditary Hemorrhagic Telangiectasia | Wiskott-Aldrich Syndrome | Hypocalcemia | Pneumonia, Viral | Prurigo Nodularis | Hyperphenylalaninemia | Porphyria Cutanea Tarda | Trichomegaly | Ocular Albinism Type 1 | Leigh Syndrome | Peripheral T-cell Lymphoma | Mitochondrial DNA Depletion Syndrome | Juvenile Hyaline Fibromatosis | Idiopathic Multicentric Castleman Disease | Carbamoyl Phosphate Synthetase I Deficiency | Chanarin-Dorfman Syndrome | Hydrops Fetalis | Diabetic Nephropathy | Sarcoma, Endometrial Stromal | Atherosclerosis | Urolithiasis | Infertility, Male | Sengers Syndrome | Melanoma, Malignant | Motion Sickness | Gitelman Syndrome | Congenital Myasthenic Syndrome | Neurofibromatosis Type 1 | Neuroendocrine Cancer | Gastroschisis | Jawad Syndrome | Fucosidosis | Genitopatellar Syndrome | Torticollis | Eccrine Porocarcinoma | Lewy Body Dementia | Anosmia, Congenital | Spinocerebellar Ataxia Type 1 | Retinal Dystrophy | Eosinophilic Asthma | Spinocerebellar Ataxia Type 31 | Schizophrenia | DICER1 Syndrome | Myofibrillar Myopathy | Adenosine Deaminase Deficiency | Zygomycosis | Iron Deficiency Anemia | Acute Lung Injury | Ganglioglioma | Glycogen Storage Disease | Cancer, Colon | Prediabetes | Pycnodysostosis | Synovitis | Malaria | CEDNIK Syndrome | Tuberculosis | Cutaneous Angiosarcoma | Nemaline Myopathy 10 | Hepatic Veno-occlusive Disease | Whipple's Disease | Nephrotic Syndrome | Benign Familial Neonatal Convulsions | Myelitis, Transverse | Epidermolysis Bullosa | Spinocerebellar Ataxia Type 20 | FG Syndrome | Corneal Neovascularization | Purpura, Thrombotic Thrombocytopenic | Angiosarcoma | Ependymoma | Microcephaly, Seizures, And Developmental Delay | WAGR Syndrome | Uveitis | Isovaleric Acidemia | Plasmacytoma | Rhabdomyosarcoma, Embryonal | Wagner Disease | KBG Syndrome | Charcot-Marie-Tooth Disease Type 3 | Osteonecrosis Of The Jaw | Corneal Ulcer | Hyperuricemic Nephropathy, Familial Juvenile | PHARC Syndrome | Niemann-Pick Disease, Type C | Phenylketonuria | Alpha-1 Antitrypsin Deficiency | Still Disease | Mabry Syndrome | Sarcoma, Ewing | Galactosialidosis | Pituitary Disorders | Diabetes Type 1 | Alkaptonuria | Glycogen Storage Disease Type 1b | Osteoporosis | Intestinal Tuberculosis | Combined Pituitary Hormone Deficiency | Waardenburg Syndrome Type 4A | Kallmann Syndrome | Norrie Disease | Renal Tubular Dysgenesis | Robinow Syndrome | Pontocerebellar Hypoplasia Type 2 | Behavioral Variant Of Frontotemporal Dementia | Subacute Sclerosing Panencephalitis | Antenatal Bartter Syndrome Type 1 | Hypervalinemia | Autoimmune Disease | Pineoblastoma | Waardenburg Syndrome Type 2E | Parkinson Disease 6, Autosomal Recessive Early-onset | Brachydactyly | Keratitis | Transient Bullous Dermolysis Of The Newborn | Diffuse Intrinsic Pontine Glioma | Hereditary Coproporphyria | Macular Corneal Dystrophy Type 1 | Progressive Encephalopathy-optic Atrophy Syndrome | Cardiomyopathy, Hypertrophic | MELAS Syndrome | Restrictive Dermopathy | Bronchiolitis | Tinea Versicolor | Fascioliasis | Klinefelter Syndrome | Eczema | Retinoschisis | Autism | Disseminated Superficial Actinic Porokeratosis | Proximal Symphalangism | Agnathia-Otocephaly Complex | Glycogen Storage Disease Type 5 | Spinocerebellar Ataxia Type 23 | Exfoliative Dermatitis | Central Retinal Artery Occlusion | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Mumps | Retinal Vasculitis | X-linked Creatine Transporter Deficiency | Delirium | Steel Syndrome | Gastritis, Atrophic | Congenital Afibrinogenemia | Acanthosis Nigricans | Guillain-Barre Syndrome | Haim-Munk Syndrome | Thyroiditis, Autoimmune | Nager Acrofacial Dysostosis | Barakat Syndrome | Diabetes Mellitus, Transient Neonatal | CDKL5 Deficiency Disorder | Richter's Syndrome | Epidermolytic Palmoplantar Keratoderma | Blepharoconjunctivitis | Polymyalgia Rheumatica | Chylomicron Retention Disease | Pelizaeus-Merzbacher Disease | Duchenne Muscular Dystrophy | Prader-Willi Syndrome | Xeroderma Pigmentosum | Pulmonary Alveolar Proteinosis | Carbohydrate Metabolism Disorders | Hypercholesterolemia | Peroxisomal Disorder | Hypertension, Portal | Ornithine Transcarbamylase Deficiency | Schizoaffective Disorder | Arts Syndrome | Knobloch Syndrome | Chloridorrhea, Congenital | Hemangioma | Crouzon Syndrome With Acanthosis Nigricans | D-2-Hydroxyglutaric Aciduria | Alveolar Capillary Dysplasia | Spinocerebellar Ataxia Type 28 | Primary Hyperoxaluria | Urticaria | Axenfeld-Rieger Syndrome | Congenital Muscular Dystrophy | Chronic Enteropathy Associated With SLCO2A1 Gene | Craniometaphyseal Dysplasia | Sertoli Cell-only Syndrome | Amblyopia | Graft-versus-host Disease | Alopecia Areata | Ectrodactyly | Bloom Syndrome | Primary Progressive Aphasia | Gout | Cancer, Bladder | Niemann-Pick Disease, Type A | Fanconi Syndrome