Nephrotic Syndrome

About the Disease
Hypoparathyroidism, Sensorineural Deafness, and Renal Dysplasia Syndrome, also known as barakat syndrome, is related to membranoproliferative glomerulonephritis and glomerulonephritis. An important gene associated with Hypoparathyroidism, Sensorineural Deafness, and Renal Dysplasia Syndrome is GATA3 (GATA Binding Protein 3), and among its related pathways/superpathways are Cell junction organization and Primary focal segmental glomerulosclerosis (FSGS). The drugs Entecavir and Furosemide have been mentioned in the context of this disorder. Affiliated tissues include kidney, heart and uterus, and related phenotypes are hypoparathyroidism and renal dysplasia

Common Targets
NPHS1 | PMM2 | ACE | DIAPH2 | HLA-B | G3320 | HLA-DRB1 | NR3C2 | G4780 | HLA-DQA1 | STIP1 | SCGB1A1 | COL4A5 | ITSN2 | KCND3 | AGT | G4851 | HMOX2 | PPP3R2 | NPHS2 | HDAC1 | SYNPO2 | ANGPTL3 | PPP3CC | LAMB2 | GAS2L2 | HLA-A | GABA(A) receptor | CD2AP | PPID | HSD11B1 | NR3C1 | MC2R | ACHE | ITGA3 | KCNJ1 | ARHGDIA | Acetylcholine Receptors (Nicotinic) (nAChR) (nonspecified subtype) | NR1I2 | TSBP1-AS1 | CD86 | RCAN2 | DLC1 | EMP2 | RTL5 | SYNPO | G3630 | TIAM1 | ACTN4 | COQ6 | G5243 | PLCE1 | KRT8 | MTHFR | VDR | HLA-DPA1 | MC3R | FKBP5 | KANK1 | SOCS3 | GLCCI1 | KCNA5 | NOS3 | ZMPSTE24 | MS4A1 | KANK4 | TRPC6 | Heme Oxygenase (HO) (nonspecified subtype) | CYP3A7 | CDK20 | LMX1B | CYP3A5 | TNFRSF11A | PREX1 | GAPVD1 | MAP7D1 | CHIA | XPO5 | PLCG1 | CD80 | CRHR1 | TNS2 | FRMPD3 | SCARB2 | G3569 | KIRREL2 | WT1 | RCAN3 | PON1 | PPP3CB | TBC1D8B | GUCY2C | Inosine 5'-monophosphate dehydrogenase (IMPDH) (nonspecified subtype) | PPP3R1 | HLA-DPB1 | NT5E | JAK2 | MIF | TNFSF15 | APOL1 | CD28 | KLHL13 | CCL2 | HLA-C | HLA-DQB1 | ASB12 | G596 | MYO1E | SEMA3G | LGALS1 | HMOX1 | COL4A4 | ITSN1 | KANK2 | ITFG2-AS1 | ALG1 | Melanocortin receptor (nonspecified subtype) | FIBCD1 | INF2 | HDAC6 | Phosphodiesterase (nonspecified subtype) | COQ2 | CYP3A4 | EDNRA | MC1R | PTPRO | PPIA | MAGI2 | Protein Phosphatase 2B | APEH | DIAPH1 | NEK3 | HCG23 | AVPR1A | G7124 | PLCG2 | SGPL1 | SMARCAL1 | LAMA5

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