Otitis Media

About the Disease
Otitis Media, also known as opsoclonus-myoclonus syndrome, is related to suppurative otitis media and chronic purulent otitis media, and has symptoms including myoclonus and ophthalmoplegia. An important gene associated with Otitis Media is A2ML1 (Alpha-2-Macroglobulin Like 1), and among its related pathways/superpathways are Innate Immune System and Disease. The drugs Halofantrine and Azithromycin have been mentioned in the context of this disorder. Affiliated tissues include eye, bone and breast, and related phenotypes are sleep disturbance and ataxia

Common Targets
BPIFA4P | TNFRSF11B | SPINK5 | RPTOR | HRH3 | IL10 | MYO7B | LDLR | ALDH1A2 | G114548 | PLD2 | G7124 | AKAP6 | AMP-activated protein kinase (AMPK) | SMIM1 | IL1B | A2ML1 | ELANE | SORCS3 | PTPRG | G3569 | Matrix Metalloproteinase (MMP) (nonspecified subtype) | ASPH | CD14 | MAOA | MECOM | G7099 | PLXDC2 | COL4A2 | Voltage-Gated Sodium Channel Complex | Toll-Like Receptor (nonspecified subtype) | GRID2 | LIN28A | CDK14 | PTPN1 | ACHE | Sodium channel (nonspecified subtype) | NOSTRIN | CAPN14 | FGF14 | HRH1 | FUT2 | IL2 | ABO | ROR2 | NR3C1 | FBXO11 | PRKG1 | DGKH | GALNT14 | MAOB

Note: If you'd like to get a target analysis report for Otitis Media, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Otitis Media at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Fowler's Syndrome | Lissencephaly 2 | Peroxisomal Disorder | Chorea-acanthocytosis | Benign Familial Neonatal Convulsions | Split Hand-foot Malformation | Renal Hypomagnesemia 3 | Bartter Syndrome | Herpes Simplex Dermatitis | Erythema Nodosum | Duane Retraction Syndrome | Pemphigus Vulgaris | Epidermodysplasia Verruciformis | Reticular Dysgenesis | Hypertension | Asphyxia Neonatorum | Polycystic Kidney, Autosomal Recessive | Cantu Syndrome | Pseudohypoparathyroidism Type 1A | Oligoasthenoteratozoospermia | Hyperprolactinemia | Pneumonia, Bacterial | Multiple Epiphyseal Dysplasia | Preaxial Polydactyly | Hashimoto Thyroiditis | Myopia | Borjeson-Forssman-Lehmann Syndrome | Giant Cell Arteritis | Unverricht-Lundborg Syndrome | Coma | Cheilitis | Raynaud Phenomenon | Abetalipoproteinemia | Maternally Inherited Diabetes And Deafness | Auriculocondylar Syndrome | Chloridorrhea, Congenital | Spinocerebellar Ataxia Type 17 | Glaucoma | Palmoplantar Keratoderma | Heart Failure | Relapsing Polychondritis | Epithelial-myoepithelial Carcinoma | Leiomyosarcoma | Hypersensitivity Pneumonitis | Leishmaniasis, Cutaneous | Keratocystic Odontogenic Tumor | Antisynthetase Syndrome | Aldosterone Deficiency | Lymphoma, Follicular | Pachyonychia Congenita | Nephrotic Syndrome | Norrie Disease | Marinesco-Sjogren Syndrome | Blepharophimosis Syndrome | Seizures-scoliosis-macrocephaly Syndrome | Lathosterolosis | Lattice Corneal Dystrophy | Epidermolytic Palmoplantar Keratoderma | Dysferlinopathy | Glomerulonephritis | Pyruvate Decarboxylase Deficiency | Spinocerebellar Ataxia Type 5 | Tietze Syndrome | Basan Syndrome | Primary Hyperoxaluria | Adenomatoid Tumor | Crouzon Syndrome With Acanthosis Nigricans | Angioedema, Hereditary | Sitosterolemia | Meesmann Corneal Dystrophy | Congenital Poikiloderma | Enlarged Vestibular Aqueduct | Peters-plus Syndrome | Early Infantile Epileptic Encephalopathy 4 | Fukuyama Congenital Muscular Dystrophy | Primary Progressive Aphasia | Neuromyelitis Optica | Heroin Dependence | Thalassemia, Beta | Cancer, Skin | 3-methylcrotonyl-CoA Carboxylase Deficiency | Purpura | Nephrotic Syndrome Type 1 | Dubin-Johnson Syndrome | Allan-Herndon-Dudley Syndrome | Osteopetrosis | Oculocutaneous Albinism | Generalized Epilepsy With Febrile Seizures Plus | Panniculitis | Spitz Nevus | Viral Meningitis | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Cryptococcal Meningitis | Budd-Chiari Syndrome | Varices | Supravalvular Aortic Stenosis | Familial Retinal Arterial Macroaneurysm | Schizotypal Personality Disorder | Loeys-Dietz Syndrome | 3-methylglutaconic Aciduria Type IV | Asperger Syndrome | Pterygium | Sensorineural Hearing Loss | Muscular Dystrophy | Pneumothorax | Waldenstrom Macroglobulinemia | Osteogenesis Imperfecta Type III | Chondromyxoid Fibroma | Hernia, Inguinal | Bietti Crystalline Dystrophy | Fibromyalgia | Disseminated Intravascular Coagulation | Congenital Stationary Night Blindness | Sweet Syndrome | Juvenile Myoclonic Epilepsy | Lung Diseases | Gardner Syndrome | Chronic Idiopathic Myelofibrosis | Smith-Lemli-Opitz Syndrome | Mannosidase Deficiency Diseases | Gastrointestinal Disorders | Portal Vein Thrombosis | Cataplexy | HIBCH Deficiency | Pelizaeus-Merzbacher Disease | Superficial Spreading Melanoma | Infantile Neuroaxonal Dystrophy | Micropenis | Aromatic L-amino Acid Decarboxylase Deficiency | Wolfram Syndrome 2 | Fundus Albipunctatus | Colitis | Autoimmune Polyendocrinopathy Syndrome Type I | Autonomic Nervous System Disorders | Alpha-mannosidosis | Cryptorchidism | Ichthyosis, X-linked | Glycogen Storage Disease Type 0 | Adenocarcinoma | Diastrophic Dysplasia | Transcobalamin Deficiency | Mitochondrial DNA Depletion Syndrome, Myopathic Form | Parkinsonism | Hypotrichosis Simplex | Gastroenteritis, Eosinophilic | Stroke, Ischemic | Schistosomiasis Mansoni | Erythema Multiforme | Miyoshi Myopathy | Insulinoma | Kidney Stones | Facioscapulohumeral Muscular Dystrophy Type 2 | Bardet-Biedl Syndrome | Osteosclerosis | Meningococcal Infections | Congenital Dyserythropoietic Anemia Type 1 | Phenylketonuria II | Thyroid Dysgenesis | Prediabetes | Cleidocranial Dysplasia | Tonsillitis | DNA Ligase IV Deficiency | Otitis Media | Adrenomyeloneuropathy | Chromosome 16p11.2 Deletion Syndrome | Adenoma, Pituitary | Spinocerebellar Ataxia Type 21 | Subacute Sclerosing Panencephalitis | Tenosynovial Giant Cell Tumor | Lesch-Nyhan Syndrome | Progressive Encephalopathy-optic Atrophy Syndrome | Dysgerminoma | Congenital Aniridia | Chediak-Higashi Syndrome | Glucagonoma | Hypercholesterolemia | Gitelman Syndrome | Autoimmune Autonomic Ganglionopathy | Chylothorax, Congenital | Non-bullous Congenital Ichthyosiform Erythroderma | Epidermolysis Bullosa Simplex With Mottled Pigmentation | Infertility, Male | Posterior Polar Cataract | Japanese Encephalitis | Neutropenia | Twin-to-twin Transfusion Syndrome | Peripheral T-cell Lymphoma | Anal Fissure | Systemic Lupus Erythematosus | Stuve-Wiedemann Syndrome | Meleda Disease | Hepatitis, Autoimmune | Thanatophoric Dysplasia Type 1 | Osteoarthritis | Scabies | Krabbe Disease | Systemic Mastocytosis | Glycogen Storage Disease Type 3 | Polyomavirus Nephropathy | Melanoma, Uveal | Renal Medullary Carcinoma | Hypertension, Essential | Pierson Syndrome | Spinocerebellar Ataxia Type 40 | Gastric Atrophy | Cherubism | Endometriosis | Aarskog-Scott Syndrome | Granular Corneal Dystrophy Type 1 | Arteriovenous Malformations | Low Tension Glaucoma | Bloom Syndrome | Tyrosinemia Type 1 | Cancer, Brain | Dysequilibrium Syndrome | Steel Syndrome | Methemoglobinemia Type IV | Rubeosis Iridis | 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Myeloid Leukemia | Cerebellofaciodental Syndrome | Cramp Fasciculation Syndrome | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | Generalized Epilepsy And Paroxysmal Dyskinesia | Acral Lentiginous Melanoma | Cardiospondylocarpofacial Syndrome | Charcot-Marie-Tooth Disease | Tic Disorder | Herpes Genitalis | Farber Disease | Sarcoma, Alveolar Soft Part | Leprosy | Carpal Tunnel Syndrome | Mucormycosis | Diabetes | Pneumococcal Meningitis | Hypermetropia | PHARC Syndrome | Intestinal Pseudo-obstruction | Lassa Fever | Hyperinsulinemic Hypoglycemia | Eccrine Porocarcinoma | Sengers Syndrome | Diabetic Macular Edema | Renal Hypouricemia | Cholelithiasis | Splenomegaly | Pitt-Hopkins Syndrome | Hyperlipidemia Type V | Depression | Hemorrhoids | Adenoid Cystic Carcinoma | Contact Dermatitis | Progressive Familial Intrahepatic Cholestasis Type 2 | Localized Scleroderma | Dystrophy, Cone-rod | Corneal Edema | Congenital Disorders Of Glycosylation Type II | Odonto-onycho-dermal Dysplasia | Large Granular Lymphocytic Leukemia | Atopic Dermatitis | Tumoral Calcinosis | Choriocarcinoma | Congenital Myopathy | Autoimmune Polyendocrine Syndrome | Leigh Syndrome | Erysipelas | Brachydactyly | Osteoporosis, Postmenopausal | Familial Digital Arthropathy-brachydactyly | Angina Pectoris | Celiac Disease | Gastritis, Atrophic | Spastic Paraplegia Type 7 | COACH Syndrome | Congenital Disorders Of Glycosylation | Multiple Hamartoma Syndrome | Primary Ovarian Insufficiency | Imerslund-Grasbeck Syndrome | Toxoplasmosis | Dyskeratosis Congenita | Hereditary Hemorrhagic Telangiectasia Type 2 | Sezary Syndrome | Paraganglioma, Carotid Body | Carney-Stratakis Syndrome | Combined Deficiency Of Factor V And Factor VIII | Neurocysticercosis | Chronic Neutrophilic Leukemia | Hypothyroidism | Metabolic Diseases | Tetraplegia | Glioma | Nevus | Hypogonadism | X-linked Creatine Transporter Deficiency | Membranous Nephropathy | Rhabdomyosarcoma, Embryonal | Hyperparathyroidism-jaw Tumor Syndrome | Inborn Errors Of Metabolism | Methemoglobinemia | REM Sleep Behavior Disorder | Mesothelioma, Malignant | Hereditary Spastic Paraplegia | Pyelonephritis | 3C Syndrome | Craniopharyngioma | Menetrier Disease | X-linked Myotubular Myopathy | Graves Disease | Achondrogenesis | Hyperparathyroidism, Secondary | Cholesteryl Ester Storage Disease | Porphyria Cutanea Tarda | Autosomal Recessive Spastic Paraplegia Type 35 | Spermatocele | Infectious Diarrhea | Angiosarcoma | Pernicious Anemia | Neural Tube Defect | Dengue Shock Syndrome | Hereditary Inclusion Body Myopathy | Chromosome 9q34.3 Deletion Syndrome | Zollinger-Ellison Syndrome | Paternal Uniparental Disomy Of Chromosome 14 | Tinea | Encephalopathy, Ethylmalonic | Lewy Body Dementia | Molybdenum Cofactor Deficiency | Anorchia | Charcot-Marie-Tooth Disease, Type 2 | Kallmann Syndrome | Stargardt Disease | Demyelinating Diseases | Cardiac Sarcoidosis | Migraine | Microcephaly | Azoospermia | Spondylosis | Stroke, Hemorrhagic | Precocious Puberty | Spinal Muscular Atrophy | Headache | Motor Neuron Diseases | Congenital Lipoid Adrenal Hyperplasia | Heart Block | Primary Pigmented Nodular Adrenocortical Disease | Hodgkin Lymphoma | Birk-Barel Syndrome | Androgenic Alopecia | Intestinal Obstruction | Benign Recurrent Intrahepatic Cholestasis 1 | DRESS Syndrome | Hemimegalencephaly | Retinal Degeneration | Neovascular Glaucoma | Iron Deficiency Anemia | Pseudohypoparathyroidism Type 2 | IMAGe Syndrome | Hypospadias | Early Infantile Epileptic Encephalopathy | MIRAGE Syndrome | Keratosis | Optic Nerve Diseases | Granular Corneal Dystrophy | Castleman Disease | Aceruloplasminemia | Carcinoma, Small Cell | Juvenile Myelomonocytic Leukemia | Vitiligo | Dyggve-Melchior-Clausen Disease | Leukodystrophies | Renal Tubular Dysgenesis | Acne | Hyperparathyroidism | Renal-hepatic-pancreatic Dysplasia | Carbohydrate Metabolism Disorders | Fanconi Anemia | Atelosteogenesis Type 1 | Ectopia Lentis, Isolated, Autosomal Recessive | Cold-induced Sweating Syndrome | Anodontia | Charcot-Marie-Tooth Disease Type 2D | LRBA Deficiency | Congenital Adrenal Hyperplasia | Diabetes Insipidus | Saethre-Chotzen Syndrome | Leukocyte Adhesion Deficiency Type 1 | Feingold Syndrome | Ophthalmoplegia | Hemophilia | Anemia | Saul-Wilson Syndrome | Lentigo | Urethritis | Renpenning Syndrome | Chondrodysplasia Punctata | Epidermolysis Bullosa Acquisita | Robinow Syndrome | Jaundice, Obstructive | Aldosterone Synthase Deficiency