Optic Nerve Diseases

About the Disease
Foster-Kennedy Syndrome, also known as disorder of the optic nerve, is related to spinal and bulbar muscular atrophy, x-linked 1 and optic nerve disease, and has symptoms including eye manifestations and sciatica. An important gene associated with Foster-Kennedy Syndrome is TMEM30B (Transmembrane Protein 30B), and among its related pathways/superpathways are Pyruvate metabolism and TCA cycle. The drugs Dalfampridine and Carbidopa have been mentioned in the context of this disorder. Affiliated tissues include eye, bone marrow and bone.

Common Targets
MAP3K12 | NDUFV1 | ALPK1 | LINGO1 | ATOH7 | TMEM126A | LRRN1 | CACNA1A | CNTN4 | MAOB | RGR | OTX2

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