Sengers Syndrome

About the Disease
Sengers Syndrome, also known as mitochondrial dna depletion syndrome 10, is related to lactic acidosis and hypertrophic cardiomyopathy, and has symptoms including fatigue and muscle weakness. An important gene associated with Sengers Syndrome is AGK (Acylglycerol Kinase), and among its related pathways/superpathways is Peroxisomal lipid metabolism. Affiliated tissues include skeletal muscle, eye and heart, and related phenotypes are nystagmus and cataract

Common Targets
AGK

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