Diabetic Nephropathy

About the Disease
Microvascular Complications of Diabetes 2, also known as microvascular complications of diabetes, susceptibility to, 2, is related to microvascular complications of diabetes 3 and background diabetic retinopathy. An important gene associated with Microvascular Complications of Diabetes 2 is EPO (Erythropoietin). The drugs Mecobalamin and Hydroxocobalamin have been mentioned in the context of this disorder. Affiliated tissues include kidney, endothelial and retina.

Common Targets
DPH1 | ACE | LOC105379399 | HFE | Integrin alphavbeta3 (vitronectin) receptor | SSTR2 | BCL2L12 | FGF18 | GSR | SUMO4 | MED13L | CHN2 | INPPL1 | NR3C2 | PHACTR1 | PDE4B | GRM5 | ADPGK | PPARA | LOC102724087 | Integrin alphaMbeta2 (MAC-1) Receptor | MYH9 | G4780 | FN3K | IL13RA1 | UBA1 | Protein kinase C (nonspecified subtype) | FOLR2 | TBC1D5 | NGFR | CYSLTR1 | CFAP61 | NCOR2 | G59272 | LGALS3 | MDK | NOS1 | WDR73 | ZNF844 | TMPRSS15 | HLA-DQA1 | PDGFRB | SLC12A3 | FFAR1 | IL7 | ZNF595 | ABTB3 | ZNF788P | G7295 | EPHX2 | F13A1 | CACNA1S | PKHD1L1 | TTC21B | G2475 | Phosphodiesterase 1 (PDE1) (nonspecified subtype) | MAOA | LPAR1 | G1950 | PLA2G4A | MIR449B | AURKB | ME1 | CDK5/p25 | TYR | SLC19A3 | LGSN | PDZK1 | SIGMAR1 | PRKCA | MGLL | IKZF1 | ADIPOQ | AGT | Endothelin-Converting Enzymes (ECE) (nonspecified subtype) | CNR1 | PPARG | NAE1 | mTOR complex 1 | MIR137 | MIR34A | TRPV1 | G142 | CASR | NWD2 | G3479 | CTSS | DNA Topoisomerase II (nonspecified subtype) | MAP3K5 | HMOX2 | TRPC5 | KEAP1 | G6352 | PGR | CDK5 | ICAM1 | APLNR | GCK | THBS2 | IRS2 | CDKAL1 | UBA3 | DGAT2 | PTGS1 | NAV3 | SLC17A3 | TBC1D9 | G23411 | CTSL | CNOT6L | PKLR | SLC22A12 | CPT1A | PDE1C | SMIM13 | CD2AP | HLA-G | ADP-Ribosyl Cyclase/cyclic ADP-Ribose Hydrolase (ADPRC) (nonspecified subtype) | ENG | HDAC5 | G9429 | NR3C1 | PIGU | ANKRD36 | LOC101929129 | TXNIP | Transforming growth factor (nonspecified subtype) | MC2R | ACHE | SCNN1D | GALNTL6 | SORCS3 | NOX4 | MLXIPL | KHK | TMOD1 | IL1RL1 | DOCK6 | PPM1E | LOC105375741 | DPP4 | NFATC2 | PDGFD | NR1I2 | CCN2 | CASP8 | SLC1A5 | SOD2 | MRC1 | TNFRSF19 | CCR2 | PPARD | CNTLN | G3605 | ADIPOQ-AS1 | S1PR2 | ADORA2A | Peroxisome Proliferator-Activated Receptors (PPAR) (nonspecified subtype) | AVPR2 | G5743 | SHROOM3 | PCSK9 | IL17C | G3630 | PGAM5-KEAP1-NRF2 Complex | TGFA | AKR1B1 | SYN3 | TGFBR1 | FLT1 | ERRFI1 | PTPN1 | BMP8A | PFKFB2 | GPX1 | G5595 | CD38 | KRT6B | VCAM1 | SCAF4 | AMP-activated protein kinase alpha1beta1gamma1 | TGM2 | XDH | SUCLG2 | IL15 | INSR | EDNRB | IGSF22 | IAPP | ITGB2 | MTNR1B | G5243 | GLO1 | IMPDH1 | ATAD3B | Casein kinase II (CKII) | GIPR | OR6X1 | XRCC3 | AVEN | NR1H4 | MTHFR | CABCOCO1 | C7orf50 | UTS2R | KDM4D | MVK | VDR | PRMT1 | S1PR3 | GCKR | PTPRJ | CLIC1 | MC3R | TPPP2 | C6orf118 | Mitogen-Activated Protein Kinase (nonspecified subtype) | G836 | PIK3C2B | SSTR4 | SERPINE1 | ATP10D | CSMD1 | SMYD4 | COL1A2 | PTGER4 | Na+/K+-ATPase (nonspecified subtype) | ZNF875 | TBC1D31 | ADORA3 | MAPK9 | NOS3 | GCLC | ELMO1 | PHOSPHO1 | LRRC31 | PLG | TRPC6 | SH3YL1 | LOC102724768 | PRKCD | SIGIRR | IL10 | TEK | PLXDC2 | Heme Oxygenase (HO) (nonspecified subtype) | KDR | LOC100130698 | PTP4A3 | Amyloid beta A4 precursor protein-binding family (APP-BP) (nonspecified subtype) | UHRF1 | WFS1 | MED15 | GREM1 | MME | NEDD8-activating enzyme E1 | Phospholipase A2, Cytosolic (nonspecified subtype) | MMP2 | SF1 | CARS1 | GABRR1 | COMMD1 | ANKRD26 | GPR84 | SUCNR1 | IL1A | PDE5A | HDAC4 | ABCC8 | CALCRL | SLC19A2 | G9734 | ABCG8 | C4orf51 | Prostanoid TP receptor (nonspecified subtype) | DDIT3 | CAPN1 | FHOD1 | CHUK | TGFB2 | GHR | SLC17A1 | G7422 | GUCY1A1 | RBL1 | IFNG | IL1B | Transforming growth factor beta (nonspecified subtype) | F5 | SIK2 | LINC02544 | PDE1B | THBS2-AS1 | NOS2 | PTH | TLR9 | PRKCB | PKM | HIPK2 | PTBP3 | G3569 | ERBB4 | TXNRD1 | ZNF365 | NOX5 | STX18 | ANO9 | GAA | NBPF20 | LPAR4 | PTPRB | NOX3 | FGF1 | SLC5A1 | AGTR1 | GPM6A | Ikzf1 | CNTNAP2 | NRXN2 | QDPR | CCR5 | Integrin alphavbeta6 receptor | SLC2A1 | OLR1 | SMPD3 | APOA1 | ENPP1 | SLC2A1-DT | SERPINF2 | CARMIL1 | SLC34A1 | MIR146A | UMOD | ACACB | SSTR5 | NAMPT | GPX4 | NOX1 | Inosine 5'-monophosphate dehydrogenase (IMPDH) (nonspecified subtype) | NEFH | CDK8 | MAPK10 | HLA-DPB1 | TSPYL2 | MC4R | APP | NLRP3 Inflammasome | NPAS2 | IL4 | JAK2 | PLA2R1 | TMEM176A | AGER | CD47 | HPSE | GPR158 | APOL1 | JAK3 | MSR1 | DRD3 | CASP1 | JAML | APOE | AGTR2 | G2069 | JAK1 | ECE1 | IKZF2 | ZNF197 | G3146 | ABCC1 | FTO | NADPH Oxidase Complex | LRP2 | PLA2G7 | G114548 | SLC2A9 | G3576 | CCL2 | NF-kappaB (NFkB) | CRBN | Nitric oxide synthase (NOS) (nonspecified subtype) | IL13 | Integrin alphavbeta1 | GLP1R | CCDC14 | DEFB1 | GMFB | G596 | F2R | FIG4 | NME7 | XRCC1 | UBR7 | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | LOC105370003 | SLC2A2 | DEDD2 | CYP11B2 | PIP4K2A | Voltage-Gated Calcium Channel alpha-2/delta (nonspecified subtype) | alpha-Amylase (nonspecified subtype) | DDAH2 | TNFRSF14 | TSBP1 | MIR9-3 | LINC01800 | IL18 | ASAP1 | NADPH Oxidase (nonspecified subtype) | TGFB3 | TRPC1 | LRP8 | PRKCE | LOC105378977 | KIT | GPD1L | ANPEP | HMOX1 | Soluble guanylyl cyclase | SCN5A | Mitogen-activated protein kinase (JNK) (nonspecified subtype) | LOC102723341 | TCF7L2 | PDE1A | PRCD | REN | GPAT4 | AOC3 | COL4A4 | CPTP | KCNH7 | Mitogen-activated protein kinase p38 (MAPK p38) (nonspecified subtype) | RHOA | G6647 | TGFB1 | LY96 | Superoxide dismutase (SOD) (nonspecified subtype) | RASSF2 | CMA1 | Vasopressin V1 Receptor (nonspecified subtype) | BSND | POLR3GL | UNC93A | G7099 | PDE4D | UCP2 | GAS6 | Phosphodiesterase (nonspecified subtype) | ZNF20 | G10413 | Glutathione peroxidase (nonspecified subtype) | CASC15 | EDNRA | GCGR | HIF1A | ITPR1 | B9D2 | ECE2 | mu-Calpain (calpain 1) | Transforming growth factor (TGF)-beta receptor (nonspecified subtype) | CAT | G29126 | BTK | PLEKHH2 | ITGAM | CYBA | MYNN | ITGA6 | KRT32 | LCAT | CDK19 | AVPR1A | SLC22A11 | KLF4 | SLC5A2 | G7124 | SLC27A3 | GPBAR1 | TBXAS1 | SFT2D1 | RNLS | PPP4R1 | PVT1 | ADAM10 | RPTOR | TRIM37 | SERPINF1 | FFAR4 | SREBF1 | TEX101 | IL33 | Phosphodiesterase IV (PDE4) (nonspecified subtype) | UNC13B | CASP7 | ADCY10 | CSF1R | MGP

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