Disease

Ureteropelvic Junction Obstruction

About the Disease
Congenital Anomalies of Kidney and Urinary Tract 2, also known as multicystic renal dysplasia, bilateral, is related to urinary tract infection and hydronephrosis, and has symptoms including flank pain An important gene associated with Congenital Anomalies of Kidney and Urinary Tract 2 is TBX18 (T-Box Transcription Factor 18), and among its related pathways/superpathways are Genes controlling nephrogenesis and Development of ureteric collection system. The drugs Pharmaceutical Solutions and Lamivudine have been mentioned in the context of this disorder. Affiliated tissues include kidney, smooth muscle and appendix, and related phenotypes are renal insufficiency and back pain

Common Targets
AGTR2

疾病靶点研报
Ureteropelvic Junction Obstruction

Note: If you'd like to get a target analysis report for Ureteropelvic Junction Obstruction, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Ureteropelvic Junction Obstruction at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Diabetes | Chronic Periodontitis | Pemphigoid | Aneurysm, Abdominal Aortic | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Autoimmune Polyendocrine Syndrome | Progressive Encephalopathy-optic Atrophy Syndrome | Spinal Muscular Atrophy Type 2 | Genee-Wiedemann Syndrome | Hyperparathyroidism-jaw Tumor Syndrome | Adenylosuccinate Lyase Deficiency | Budd-Chiari Syndrome | Azoospermia | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Nephronophthisis | Heavy Chain Disease | Malonyl-CoA Decarboxylase Deficiency | Ophthalmoplegia | Hydrocephalus, Normal Pressure | Colorectal Adenoma | Spondyloepiphyseal Dysplasia Tarda, X-linked | Neurofibromatosis Type 2 | Renal Medullary Carcinoma | Binge Eating Disorder | Thalassemia, Beta | Papilloma | Carcinoma, Small Cell | Blood Protein Disorders | Creatine Deficiency Syndrome Due To AGAT Deficiency | Hypodontia | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Fabry's Disease | Craniofrontonasal Syndrome | Nicotine Addiction | Aplastic Anemia | Thyroiditis | D-2-Hydroxyglutaric Aciduria | Norrie Disease | Stiff-man Syndrome | Spondylocostal Dysostosis | Hyperlipidemia Type V | Cutis Laxa | Congenital Disorders Of Glycosylation Type II | Hypertelorism | Ulcerative Colitis | Dysthymia | Waardenburg Syndrome | DRESS Syndrome | Thrombophlebitis | Goiter | Esthesioneuroblastoma | Glycogen Storage Disease Type 1b | Jalili Syndrome | Purpura | IgA Deficiency | Liddle Syndrome | Vici Syndrome | Oculopharyngeal Muscular Dystrophy | Restless Legs Syndrome | Conjunctivitis, Allergic | Chondromyxoid Fibroma | Malaria, Cerebral | Spinocerebellar Ataxia Type 2 | Retinopathy, Diabetic | Epithelial-myoepithelial Carcinoma | Renal Hypouricemia | Thalassemia | ACTH-independent Macronodular Adrenal Hyperplasia | Anti-glomerular Basement Membrane Disease | Takayasu's Arteritis | Cerebellofaciodental Syndrome | Myotonia | Alkaptonuria | Familial Isolated Hyperparathyroidism | Angiosarcoma | Spinal And Bulbar Muscular Atrophy | Keratocystic Odontogenic Tumor | Congenital Hereditary Endothelial Dystrophy Type II | Focal Dermal Hypoplasia | Noonan Syndrome | Spondylocarpotarsal Synostosis Syndrome | Hereditary Xerocytosis | Veno-occlusive Disease | Myositis, Focal | Oculocutaneous Albinism Type 2 | Distal Spinal Muscular Atrophy | Megalencephaly | Seizures | Mesothelioma, Malignant | Neutropenia | Zollinger-Ellison Syndrome | Osteoglophonic Dysplasia | Peeling Skin Syndrome Type B | Acute Coronary Syndrome | Myofibrillar Myopathy | Bursitis | Hypercholesterolemia, Familial | Eiken Syndrome | Bone Marrow Necrosis | Inflammatory Joint Disease | Myopathy | Ameloblastoma | Progressive Familial Intrahepatic Cholestasis | Antenatal Bartter Syndrome Type 1 | Rosacea | Split Hand-foot Malformation | Ocular Hypertension | Focal Cortical Dysplasia Type 2 | Atrioventricular Septal Defect | Benign Recurrent Intrahepatic Cholestasis 1 | Iron Metabolism Disorders | T-cell Prolymphocytic Leukemia | Myosin Storage Myopathy | Analgesia | Pseudohermaphroditism | Nemaline Myopathy 8 | Cholestasis | Kashin-Beck Disease | Hypotrichosis Simplex | GATA2 Deficiency | Lipodystrophy | Woodhouse-Sakati Syndrome | Autism | Hyperinsulinemia | Hemangioblastoma | Thromboembolism | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Crohn's Disease | X-linked Acrogigantism | Long QT Syndrome Type 3 | Citrullinemia | Chitayat Syndrome | Encephalitis, Tick-borne | Primary Pigmented Nodular Adrenocortical Disease | Joubert Syndrome 2 | X-linked Myotubular Myopathy | Dysferlinopathy | MIRAGE Syndrome | Polydactyly | Chylomicron Retention Disease | Headache | Alopecia | Coffin-Siris Syndrome | Spinocerebellar Ataxia Type 10 | Sertoli Cell-only Syndrome | Familial Cerebral Amyloid Angiopathy | Ophthalmia, Sympathetic | LRBA Deficiency | Congestive Heart Failure | Osteopathia Striata With Cranial Sclerosis | Otopalatodigital Syndrome Type 2 | Cellulitis | Epidermolysis Bullosa Acquisita | Menetrier Disease | Ichthyosis, X-linked | Xeroderma Pigmentosum | Biotinidase Deficiency | Sezary Syndrome | Cockayne Syndrome | Multiple Congenital Anomalies-hypotonia-seizures Syndrome 2 | Familial Advanced Sleep Phase Syndrome | Hereditary Elliptocytosis | Dystonia Musculorum Deformans | Exfoliative Dermatitis | Hypohidrotic Ectodermal Dysplasia, X-linked | Multiple Myeloma | Osteitis | Cataplexy | Oculocutaneous Albinism | Hypohidrotic Ectodermal Dysplasia | Dengue Shock Syndrome | Duane Retraction Syndrome | Crigler-Najjar Syndrome | Meningitis | Primary Familial Brain Calcification | Niemann-Pick Disease, Type C | B-cell Prolymphocytic Leukemia | Sotos Syndrome | Bethlem Myopathy | Myofibromatosis | Presbyopia | Epilepsy, Generalized | NGLY1 Deficiency | Cutaneous Mastocytosis | Congenital Absence Of Vas Deferens | Netherton Syndrome | Focal Facial Dermal Dysplasia | Cerebrovascular Disorders | Pulmonary Tuberculosis | Glaucoma, Congenital | Arrhythmogenic Right Ventricular Cardiomyopathy | Hyperekplexia | Microphthalmia, Syndromic 7 | Von Hippel-Lindau Disease | Follicular Dendritic Cell Sarcoma | Esophageal Carcinoma | Autoimmune Polyendocrinopathy Syndrome Type I | Adrenal Insufficiency | Agnathia-Otocephaly Complex | Dermatitis | Giant Cell Arteritis | Parkinsonism | Parkinson's Disease | Corneal Neovascularization | Spinocerebellar Ataxia Type 21 | Metabolic Syndrome | Epidermolytic Hyperkeratosis | Disseminated Superficial Actinic Porokeratosis | Double Outlet Right Ventricle | GLUT1 Deficiency Syndrome | Neuromyelitis Optica | Vitamin K Deficiency | Atopy | Skin Carcinoma | Nemaline Myopathy 10 | Epithelioid Hemangioma | Tyrosinemia Type 2 | Ischemia | Pyruvate Dehydrogenase Deficiency | Bulimia Nervosa | Cystinuria | Hyperparathyroidism, Primary | Tendinitis | Cancer, Bladder | Angioedema, Acquired | Calcium Pyrophosphate Deposition Disease | Keloid | Cherubism | Spinocerebellar Ataxia Type 16 | Hyperammonemia | Coronary Artery Disease | Schaaf-Yang Syndrome | Hepatoblastoma | Krabbe Disease | Neurofibrosarcoma | Vitamin B12 Deficiency | Omenn Syndrome | Papillon-Lefevre Syndrome | Alstrom Syndrome | Pemphigus | Periodic Limb Movement Disorder | Neurofibroma | Dent Disease | Infectious Diarrhea | Chondrodysplasia Punctata 2, X-linked Dominant | SAPHO Syndrome | Phenylketonuria II | Diabetes Insipidus | Blau Syndrome | Bernard-Soulier Syndrome | Spondyloperipheral Dysplasia | Spinocerebellar Ataxia Type 6 | Epidermolysis Bullosa Dystrophica | Spinal Muscular Atrophy Type 3 | Dementia | Hypertension | Nijmegen Breakage Syndrome | Pyruvate Carboxylase Deficiency Disease | Lactose Intolerance | Hemolytic Anemia | Hereditary Hemorrhagic Telangiectasia Type 2 | Neuronal Ceroid Lipofuscinosis | Charcot-Marie-Tooth Disease Axonal Type 2N | Fuchs Dystrophy | Corneal Dystrophy And Perceptive Deafness | Menkes Disease | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Primary Progressive Aphasia | Shwachman-Bodian-Diamond Syndrome | Acute Tubular Necrosis | Coloboma | Mucormycosis | Iron Deficiency Anemia | Galloway-Mowat Syndrome | Ghosal Syndrome | Rhizomelic Chondrodysplasia Punctata | Impulse Control Disorder | Neovascular Glaucoma | Methylmalonic Aciduria And Homocystinuria, CblC Type | Mountain Sickness | Precocious Puberty | Exostoses | Genitopatellar Syndrome | Lymphangioleiomyomatosis | Pierpont Syndrome | Cavitary Optic Disc Anomalies | Irritable Bowel Syndrome | Retinitis Pigmentosa 3 | Glioma | Eosinophilic Asthma | Epidermodysplasia Verruciformis | Kawasaki Disease | Macrophagic Myofasciitis | Gallstones | Hypervalinemia | Gitelman Syndrome | Myhre Syndrome | Juvenile Polyposis | Pitt-Hopkins Syndrome | Hyperthermia, Malignant | Alagille Syndrome | Neurodegeneration Due To Cerebral Folate Transport Deficiency | Teratozoospermia | Adenosine Deaminase 2 Deficiency | Mixed Connective Tissue Disease | Leri Pleonosteosis | Combined Deficiency Of Factor V And Factor VIII | Carbonic Anhydrase VA Deficiency | Deafness, Dystonia, And Cerebral Hypomyelination | Osteogenesis Imperfecta Type VI | Osmotic Demyelination Syndrome | Gynecomastia | Interstitial Lung Diseases | Pyloric Stenosis, Infantile Hypertrophic | Ocular Surface Squamous Neoplasia | Lattice Corneal Dystrophy Type 1 | Coronary Heart Disease | Congenital Myasthenic Syndrome | Phosphoenolpyruvate Carboxykinase Deficiency, Cytosolic | Hyperostosis | Adult Polyglucosan Body Disease | Gray Platelet Syndrome | Potocki-Shaffer Syndrome | Pyruvate Decarboxylase Deficiency | Progressive External Ophthalmoplegia | Gerstmann-Straussler-Scheinker Syndrome | Pseudohypoaldosteronism | Impetigo | Antithrombin III Deficiency | Ileitis | Kernicterus | Pulmonary Veno-occlusive Disease | Keratoconjunctivitis | Acromicric Dysplasia | Rotor Syndrome | Stroke, Hemorrhagic | Hypertensive Retinopathy | Erythropoietic Protoporphyria | Pterygium | Chronic Granulomatous Disease, X-linked | Bartter Syndrome | Alazami Syndrome | Trichuriasis | Empyema | Acne Vulgaris | Paracoccidioidomycosis | Periventricular Nodular Heterotopia | Sulfite Oxidase Deficiency | Pupil Disorders | Hyperinsulinism-hyperammonemia Syndrome | Astigmatism | Hyperacusis | Charcot-Marie-Tooth Disease Type 2E | Epidermolysis Bullosa Simplex With Mottled Pigmentation | Bullous Pemphigoid | Dystrophy, Cone-rod | Smith-Magenis Syndrome | Van Der Knaap Disease | LMNA-related Congenital Muscular Dystrophy | Amyloidosis | 3-methylglutaconic Aciduria | Cancer, Breast | Smith-Kingsmore Syndrome | Carcinoma, Transitional Cell | Still Disease | 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Hereditary Neuropathy With Liability To Pressure Palsies | Hypothalamic Obesity | Iron Overload | PHARC Syndrome | Microvillus Inclusion Disease | Porphyria | Pneumonia, Bacterial | Malignant Fibrous Histiocytoma | Optic Nerve Hypoplasia, Bilateral | Autosomal Recessive Spastic Paraplegia Type 75 | Hyperuricemic Nephropathy, Familial Juvenile | Uremic Pruritus | Cryopyrin-associated Periodic Syndromes | Cold-induced Sweating Syndrome | Cancer, Brain | Agoraphobia | Basal Cell Nevus Syndrome | Hypertrophy | Colitis, Lymphocytic | Partington Syndrome | Isobutyryl-CoA Dehydrogenase Deficiency | Glutaric Aciduria Type 2 | Choroideremia | Neutrophilia | Acral Lentiginous Melanoma | Cataract | Megaloblastic Anemia | Stomatitis | Lafora Disease | Periodontitis | ICF Syndrome | Saethre-Chotzen Syndrome | Premenstrual Syndrome | Sleep Apnea, Obstructive