Myofibrillar Myopathy

About the Disease
Myofibrillar Myopathy, also known as desmin related myopathy, is related to myopathy, myofibrillar, 9, with early respiratory failure and myopathy, myofibrillar, 6, and has symptoms including facial paresis An important gene associated with Myofibrillar Myopathy is DES (Desmin), and among its related pathways/superpathways is Striated muscle contraction pathway. Affiliated tissues include heart, skeletal muscle and smooth muscle, and related phenotypes are muscle and behavior/neurological

Common Targets
FLNC | TMPO | DNAJB6 | LDB3 | STIM1 | FHL1 | MYOT | TTN | CRYAB | UNC45B | ACTA1 | DNAJB4 | BAG3 | DES | PYROXD1

Note: If you'd like to get a target analysis report for Myofibrillar Myopathy, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Myofibrillar Myopathy at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Granuloma Annulare | Argininosuccinic Aciduria | Eosinophilia | Spinocerebellar Ataxia Type 27 | McLeod Syndrome | Megaloblastic Anemia | Occipital Neuralgia | Thrombophilia | Neuroma | Blau Syndrome | Silver-Russell Syndrome | X-linked Charcot-Marie-Tooth Disease | T-cell Chronic Lymphocytic Leukemia | 3-methylcrotonyl-CoA Carboxylase Deficiency | Angioedema, Hereditary | Schaaf-Yang Syndrome | Androgen Insensitivity | Osteogenesis Imperfecta Type II | Osteogenesis Imperfecta Type I | Charcot-Marie-Tooth Disease | Progressive Familial Intrahepatic Cholestasis Type 2 | Arthritis, Psoriatic | Cryoglobulinemia | Herpes Simplex Dermatitis | Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress | Hypohidrotic Ectodermal Dysplasia, X-linked | Lymphoma, B-cell | Alpha-1 Antitrypsin Deficiency | Familial Episodic Pain Syndrome | Heart Septal Defects | Norrie Disease | Bacterial Meningitis | Fahr Disease | Bartter Syndrome | Palsy, Cerebral | Cancer, Kidney | Erdheim-Chester Disease | HELLP Syndrome | Neuroectodermal Tumors, Primitive | Hypokalemia | Meesmann Corneal Dystrophy | Pontocerebellar Hypoplasia Type 2 | Rolandic Epilepsy | Renal Hypomagnesemia 3 | Neuromyotonia | Multiple System Atrophy | Congenital Stationary Night Blindness | Anovulation | Stargardt Disease | Mitochondrial DNA Depletion Syndrome | Tonsillitis | Adenosine Deaminase 2 Deficiency | Cancer, Brain | Hypospadias | Sclerocornea | Sialidosis Type I | Situs Inversus | Epidermolysis Bullosa Simplex | Arteriosclerosis | Osteogenesis Imperfecta Type V | Sleep Apnea, Obstructive | Takenouchi-Kosaki Syndrome | Glycogen Storage Disease Type 1b | Osteoglophonic Dysplasia | Plasma Cell Leukemia | Hepatitis, Autoimmune | Gingivitis | Withdrawal Syndrome | Alagille Syndrome | Acromesomelic Dysplasia | Skin Carcinoma | Cousin Syndrome | Beare-Stevenson Syndrome | Impulse Control Disorder | Lymphedema-distichiasis Syndrome | Fraser Syndrome | Waardenburg Syndrome | Hydronephrosis | Babesiosis | Vascular Cognitive Impairment | Hyperbilirubinemia | Tetraplegia | Myelomeningocele | Pseudoachondroplasia | Proteasome-associated Autoinflammatory Syndrome 2 | Schnitzler Syndrome | Psoriasis | Fatty Aldehyde Dehydrogenase Deficiency | Hemochromatosis Type 1 | Keratopathy | Alpha-mannosidosis | Rubinstein-Taybi Syndrome | Epidermolysis Bullosa Simplex, Generalized | Familial Male-limited Precocious Puberty | Sulfite Oxidase Deficiency | Vitelliform Macular Dystrophy | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Dubin-Johnson Syndrome | Leukemia-lymphoma, Adult T-cell | Abetalipoproteinemia | Oculodentodigital Dysplasia | Chronic Mucocutaneous Candidiasis | Choroideremia | Bronchiectasis | Infertility | Cerebral Amyloid Angiopathy | Arthropathy | Kearns-Sayre Syndrome | IgA Deficiency | Congenital Primary Aphakia | Gilbert Syndrome | Cri-du-chat Syndrome | Eccrine Porocarcinoma | Cholangitis | Leishmaniasis, Cutaneous | Blue Nevus | Charcot-Marie-Tooth Disease, Type 2A | Familial Isolated Hyperparathyroidism | Hypertension, Renovascular | Loeys-Dietz Syndrome | Papillorenal Syndrome | Hepatitis, Alcoholic | Diamond-Blackfan Anemia | Hemorrhoids | Polydactyly | Chronic Periodontitis | C3 Glomerulopathy | Nephrocalcinosis | Renal Medullary Carcinoma | Orthostatic Intolerance | Riboflavin Transporter Deficiency Neuronopathy | Tendinopathy | Hemolytic Uremic Syndrome, Atypical | Axenfeld-Rieger Syndrome | Multiple Sclerosis, Primary Progressive | Hypertension, Renal | Prune Belly Syndrome | Chondromyxoid Fibroma | Cone Dystrophy | Hypertelorism | Angiomyolipoma | Pulverulent Zonular Cataract | Restless Legs Syndrome | Hepatic Steatosis | Camptocormia | Arthritis | Roberts Syndrome | Urolithiasis | Hyperparathyroidism, Primary | Double Outlet Right Ventricle | Angioedema, Acquired | Osteoporosis | Esophageal Motility Disorders | Charcot-Marie-Tooth Disease Type 3 | Retinoschisis | Renal Tubular Dysgenesis | Retinal Degeneration | Pityriasis Rubra Pilaris | Succinic Semialdehyde Dehydrogenase Deficiency | Nicolaides-Baraitser Syndrome | Tricho-hepato-enteric Syndrome | Joubert Syndrome 2 | Spinocerebellar Ataxia Type 1 | Blomstrand Osteochondrodysplasia | Sarcoidosis, Pulmonary | Stromal Corneal Dystrophy | PASLI Disease | Globozoospermia | Macular Corneal Dystrophy Type 1 | Multicystic Renal Dysplasia | Cantu Syndrome | Shock, Cardiogenic | Pearson Syndrome | Spinal Muscular Atrophy Type 2 | Cerebellofaciodental Syndrome | Chronic Idiopathic Myelofibrosis | Chronic Granulomatous Disease, X-linked | Glutathione Synthetase Deficiency | Methemoglobinemia Type IV | Osteomyelitis | Hepatitis | Hydrops Fetalis | Cushing Syndrome | Syncope | Hypertension, Portal | Renal Dysplasia | Hypertension, Pulmonary | Motion Sickness | Snyder-Robinson Syndrome | Congenital Lipoid Adrenal Hyperplasia | Congenital Dyserythropoietic Anemia | Multiple Hamartoma Syndrome | Shwachman-Bodian-Diamond Syndrome | Mevalonate Kinase Deficiency | Congenital Dysfibrinogenemia | Familial Advanced Sleep Phase Syndrome | Glioblastoma Multiforme | Fibromuscular Dysplasia | Distal Myopathy 2 | Syndactyly | Leber Hereditary Optic Neuropathy | Optic Neuropathy | Waardenburg Syndrome Type 4A | Odonto-onycho-dermal Dysplasia | REM Sleep Behavior Disorder | Goiter, Nodular | Primary Aldosteronism | Parkinsonism | Gardner Syndrome | Arthritis, Reactive | Follicular Dendritic Cell Sarcoma | Galactosialidosis | Congenital Fiber-type Disproportion Myopathy | Tetanus | Insulinoma | Aneurysm, Abdominal Aortic | Lysosomal Acid Lipase Deficiency | Heroin Dependence | Asperger Syndrome | Agnathia-Otocephaly Complex | T-cell Prolymphocytic Leukemia | Oral Lichen Planus | Bainbridge-Ropers Syndrome | Osteonecrosis | Sporadic Inclusion Body Myositis | Reticular Dysgenesis | Wolff-Parkinson-White Syndrome | Primary Hyperoxaluria Type 3 | Coffin-Siris Syndrome | Primary Sclerosing Cholangitis | Inflammatory Joint Disease | Encephalitis | Peutz-Jeghers Syndrome | Communication Disorders | Trismus-pseudocamptodactyly Syndrome | Pyloric Stenosis, Infantile Hypertrophic | Varicocele | Light Chain Amyloidosis | Primary Progressive Nonfluent Aphasia | Congenital Bilateral Absence Of Vas Deferens | Achondrogenesis | Ectrodactyly | Gastroenteritis, Eosinophilic | Hyperlipidemia Type V | Acute Lymphocytic Leukemia | Erythromelalgia | Craniolenticulosutural Dysplasia | Primary Pigmented Nodular Adrenocortical Disease | Chondrodysplasia Punctata 2, X-linked Dominant | Nemaline Myopathy 10 | Lichen Planus | Disseminated Superficial Actinic Porokeratosis | Neurofibroma, Plexiform | Pterygium | Tumoral Calcinosis | Hemangioma | Warsaw Breakage Syndrome | Brenner Tumor | Hypertrophy | Sengers Syndrome | Hepatoblastoma | Poikiloderma With Neutropenia | Takayasu's Arteritis | Erythrokeratodermia Variabilis | Rickets | Mitochondrial DNA Depletion Syndrome 13 | Conjunctivitis | X-linked Creatine Transporter Deficiency | Tularemia | DEND Syndrome | Neurodermatitis | Eiken Syndrome | Toxoplasmosis | Esophagitis, Eosinophilic | Pathological Gambling | Corneal Dystrophy | Pancytopenia | Ocular Albinism Type 1 | Aldosterone Synthase Deficiency | Dermatofibrosarcoma | Spinocerebellar Ataxia Type 38 | Thrombasthenia | Headache | Paraganglioma | Scleroderma | Infantile Refsum Disease | Miyoshi Myopathy | Episodic Ataxia Type 2 | Cancer, Bladder | Polycystic Kidney, Autosomal Dominant | Triphalangeal Thumb-polysyndactyly Syndrome | Episodic Ataxia Type 1 | Citrullinemia | Schamberg Disease | Nestor-Guillermo Progeria Syndrome | Spinal And Bulbar Muscular Atrophy | Heart Failure | Maple Syrup Urine Disease | Carcinoma, Transitional Cell | Keratosis | Eclampsia | Traboulsi Syndrome | Juvenile Myelomonocytic Leukemia | Thyrotoxic Periodic Paralysis | Spasticity | Spondyloperipheral Dysplasia | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Pain | Ulcerative Colitis | Hemolytic Uremic Syndrome | Hypotrichosis Simplex | Uremia | Large Granular Lymphocytic Leukemia | Paroxysmal Nocturnal Hemoglobinuria | Hidradenitis Suppurativa | Progressive Familial Intrahepatic Cholestasis Type 1 | Retinoblastoma | Hypercholesterolemia, Familial | Progressive Encephalopathy-optic Atrophy Syndrome | Hypertensive Nephropathy | Thanatophoric Dysplasia Type 1 | Optic Neuritis | Epidermal Nevus Syndrome | Hereditary Hemorrhagic Telangiectasia Type 2 | Scoliosis | Vitreoretinal Degeneration, Snowflake Type | Chronic Enteropathy Associated With SLCO2A1 Gene | Spermatocele | Mood Disorder | Tic Disorder | Phenylketonuria | Arrhythmogenic Right Ventricular Cardiomyopathy | Hemophagocytic Lymphohistiocytosis | Supravalvular Aortic Stenosis | Atelosteogenesis Type 2 | Fibrodysplasia Ossificans Progressiva | Epilepsy, Generalized | Stomatitis | Premenstrual Syndrome | Hepatitis E | GM2-gangliosidosis AB Variant | Gout | Epidermolytic Palmoplantar Keratoderma | Blue Rubber Bleb Nevus Syndrome | Perry Syndrome | Major Depression | Methylmalonic Acidemia | Cystitis, Interstitial | Primary Hyperoxaluria | Hepatitis A | Dystrophy, Cone-rod | Cyclic Vomiting Syndrome | CHARGE Syndrome | Growth Hormone Excess | Schistosomiasis | Glycogen Storage Disease Type 0, Muscle | Mabry Syndrome | Esthesioneuroblastoma | Raynaud Phenomenon | Chloridorrhea, Congenital | Ophthalmoplegia | Metaphyseal Chondrodysplasia, Schmid Type | Renal Hypouricemia | Lewy Body Dementia | Parvovirus B19 Infection | Benign Familial Infantile Seizures | Best Macular Dystrophy | Periventricular Leukomalacia | Long-chain 3-hydroxyacyl-coenzyme A Dehydrogenase Deficiency | Neurogenic Bladder | Usher Syndrome Type II | Glaucoma, Congenital | Thyroid Dyshormonogenesis | Epicondylitis | Panuveitis | Microphthalmia | Tinea Versicolor | Chronic Myeloid Leukemia | Hereditary Hemorrhagic Telangiectasia | Congenital Muscular Dystrophy | Spinocerebellar Ataxia Type 6 | Hemosiderosis | Lipoma | Encephalocele | Patent Ductus Arteriosus | Spondyloepiphyseal Dysplasia Tarda, X-linked | Binge Eating Disorder | Malaria | Congenital Afibrinogenemia | Glutaric Aciduria Type 3 | Waardenburg Syndrome Type 2A | Blepharophimosis Syndrome | Autism | Twin-to-twin Transfusion Syndrome | Compartment Syndrome | Anodontia | Systemic Mastocytosis | Smoldering Myeloma | Hermansky-Pudlak Syndrome | Primary Erythromelalgia