Usher Syndrome Type II

About the Disease
Usher Syndrome Type 2, also known as ush2, is related to usher syndrome, type iic and usher syndrome, type iid. An important gene associated with Usher Syndrome Type 2 is USH2A (Usherin), and among its related pathways/superpathways are Olfactory Signaling Pathway and Ciliary landscape. The drug Varespladib methyl has been mentioned in the context of this disorder. Affiliated tissues include eye, retina and cerebellum, and related phenotypes are sensorineural hearing impairment and abnormal electroretinogram

Common Targets
MYO7A | ADGRV1 | USH2A | CLRN1 | WHRN | USH1G | USH1C | CDH23

Note: If you'd like to get a target analysis report for Usher Syndrome Type II, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Usher Syndrome Type II at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Hernia, Inguinal | Pelvic Inflammatory Disease | Thrombophlebitis | Hoyeraal-Hreidarsson Syndrome | Central Core Disease | T-cell Chronic Lymphocytic Leukemia | C3 Glomerulopathy | Beare-Stevenson Syndrome | Retinoschisis | Glutathione Synthetase Deficiency | Hypervalinemia | Progressive Familial Intrahepatic Cholestasis Type 3 | FG Syndrome | Hemochromatosis Type 1 | Macrophagic Myofasciitis | Polycystic Kidney, Autosomal Recessive | Epithelioid Hemangioma | Cholestasis | Waardenburg Syndrome Type 4 | Perivascular Epithelioid Cell Tumor | Hypoproteinemia, Hypercatabolic | Porphyria Cutanea Tarda | Salla Disease | Poikiloderma With Neutropenia | Maple Syrup Urine Disease | Chromosome 16p11.2 Deletion Syndrome | Stiff-man Syndrome | Arteriosclerosis | Plasmacytoma | Pantothenate Kinase-associated Neurodegeneration | Hereditary Inclusion Body Myopathy | Epidermal Nevus Syndrome | Early Infantile Epileptic Encephalopathy 4 | Hypospadias | Osteogenesis Imperfecta | Trachoma | Phenylketonuria | LMNA-related Congenital Muscular Dystrophy | Tuberculous Meningitis | Myelodysplasia | Polycystic Liver | Relapsing Polychondritis | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Vascular Calcification | Congenital Hemolytic Anemia | Hemolytic Uremic Syndrome | Pyoderma Gangrenosum | McLeod Syndrome | Graft-versus-host Disease | Priapism | Pituitary Stalk Interruption Syndrome | Pemphigoid | Sarcoidosis | Hepatitis | Patent Ductus Arteriosus | 5-oxoprolinase Deficiency | GNE Myopathy | Pituitary Disorders | Carcinoma In Situ | Retinal Coloboma | Autosomal Recessive Spastic Paraplegia Type 54 | Tietze Syndrome | Arts Syndrome | Gastritis | Long-chain 3-hydroxyacyl-coenzyme A Dehydrogenase Deficiency | Juvenile Myelomonocytic Leukemia | Hemochromatosis | Robinow Syndrome | Anorectal Malformations | Giant Axonal Neuropathy | Hemangioblastoma | Stuttering | Acne Vulgaris | Hereditary Hemorrhagic Telangiectasia Type 2 | Ovarian Hyperstimulation Syndrome | Chromosome 17q21.31 Deletion Syndrome | Trismus-pseudocamptodactyly Syndrome | Hidradenitis | Early Infantile Epileptic Encephalopathy 28 | Diabetes Insipidus, Neurogenic | B-cell Prolymphocytic Leukemia | Brooke-Spiegler Syndrome | Glycogen Storage Disease Type 5 | Hemosiderosis | Anorchia | Epiphyseal Chondrodysplasia, Miura Type | Saethre-Chotzen Syndrome | Oculocutaneous Albinism Type 1 | Okihiro Syndrome | Hidradenitis Suppurativa | Erythrokeratodermia Variabilis | Harlequin Ichthyosis | Myocardial Infarction | Rhabdomyosarcoma | Apparent Mineralocorticoid Excess Syndrome | Myelofibrosis | Systemic Mastocytosis | Urea Cycle Disorder | Clouston Hidrotic Ectodermal Dysplasia | Rhabdomyosarcoma, Alveolar | Growth Hormone Excess | Omenn Syndrome | Mesothelioma, Malignant | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Glutaric Aciduria Type 1 | Low Tension Glaucoma | Neonatal Progeroid Syndrome | Jaundice, Obstructive | Intestinal Tuberculosis | Multiple Myeloma | Gastric Atrophy | Spinocerebellar Ataxia Type 17 | Wieacker-Wolff Syndrome | Compartment Syndrome | Desbuquois Syndrome | Hypobetalipoproteinemias | Mosaic Variegated Aneuploidy Syndrome 2 | Cone Dystrophy | Hypothalamic Obesity | Scleroderma | Evans Syndrome | Ellis-Van Creveld Syndrome | Odonto-onycho-dermal Dysplasia | Rhabdoid Tumor | Pfeiffer Syndrome | Cerebral Cavernous Malformations | NDH Syndrome | Choroideremia | Plasma Cell Dyscrasia | Alpha-mannosidosis | VACTERL/VATER Association | Autoimmune Polyendocrine Syndrome | Megalencephaly | Klinefelter Syndrome | Hypoplastic Left Heart Syndrome | X-linked Creatine Transporter Deficiency | Gout | Progressive Familial Intrahepatic Cholestasis | Dwarfism | Pneumothorax | Lymphomatoid Granulomatosis | Motion Sickness | CDKL5 Deficiency Disorder | Early Infantile Epileptic Encephalopathy | Lattice Corneal Dystrophy | Liver Failure | Acne | CREST Syndrome | Antenatal Bartter Syndrome Type 1 | Smith-Lemli-Opitz Syndrome | Anxiety Disorders | Pulmonary Alveolar Proteinosis | Syphilis | Acrodysostosis | Primary Carnitine Deficiency | Methylmalonic Aciduria And Homocystinuria, CblC Type | Hypokalemic Periodic Paralysis | Alzheimer Disease, Late Onset | Prurigo Nodularis | Familial Exudative Vitreoretinopathy | Microtia | Vertebrobasilar Insufficiency | Pseudoachondroplasia | Episodic Ataxia Type 2 | Diabetic Encephalopathy | Congenital Sodium Diarrhea | Ependymoma | Arthritis, Psoriatic | Methemoglobinemia Type IV | Goldenhar Syndrome | Leukocyte Adhesion Deficiency | Eosinophilia | Bronchiolitis | Juvenile Myoclonic Epilepsy | Familial Retinal Arterial Macroaneurysm | Genitopatellar Syndrome | Familial Mediterranean Fever | Delayed Sleep Phase Syndrome | Superficial Spreading Melanoma | Neurocutaneous Syndromes | Branchiootorenal Syndrome | Sarcoma | Papulopustular Rosacea | Glomerulonephritis, Membranous | Heterotopic Ossification | Cannabis Abuse | Granuloma Annulare | Nutrition Disorders | Preaxial Polydactyly | Neurofibroma, Plexiform | Myelitis, Transverse | Parkinsonism | Fetal And Neonatal Alloimmune Thrombocytopenia | Erythropoietic Protoporphyria | Acute Myeloid Leukemia | Endometriosis | Nicotine Addiction | Spinocerebellar Ataxia Type 23 | Atelosteogenesis Type 2 | Autoimmune Autonomic Ganglionopathy | Fanconi Anemia | Birt-Hogg-Dube Syndrome | Pancytopenia | Niemann-Pick Disease | HIBCH Deficiency | N-acetylglutamate Synthase Deficiency | Lymphoma, Mantle Cell | Adrenal Insufficiency | Familial Hypertrophic Cardiomyopathy | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Zygomycosis | Chediak-Higashi Syndrome | Anal Fissure | Hamartoma | Myositis, Focal | T-cell Lymphoma, Subcutaneous Panniculitis-like | Paraganglioma | Arthritis, Reactive | D-2-Hydroxyglutaric Aciduria | Corneal Dystrophy And Perceptive Deafness | Peyronie's Disease | Analgesia | Chromosome 8q21.11 Deletion Syndrome | Congenital Heart Block | Spinocerebellar Ataxia | Alazami Syndrome | Conjunctivitis | Autism Spectrum Disorders | Holt-Oram Syndrome | Nephroblastoma | Arthropathy | Cole-Carpenter Syndrome | Hyperlipidemia | Charcot-Marie-Tooth Disease, Type 2C | Gigantism | Familial Episodic Pain Syndrome | 3-hydroxy-3-methylglutaryl-CoA Synthase Deficiency | Split Hand-foot Malformation | Acromesomelic Dysplasia | Palmoplantar Keratoderma | Oral Lichen Planus | Papillon-Lefevre Syndrome | Fibronectin Glomerulopathy | Meningococcal Infections | Primary Hyperoxaluria | Viral Meningitis | Congenital Dyserythropoietic Anemia | Bartter Syndrome | Adrenomyeloneuropathy | Charcot-Marie-Tooth Disease Type 2D | Renal Tubular Dysgenesis | Cryptococcal Meningitis | Porokeratosis | Loeys-Dietz Syndrome Type 4 | Molybdenum Cofactor Deficiency | Noonan Syndrome | Renal-hepatic-pancreatic Dysplasia | Acrodermatitis | Glanzmann Thrombasthenia | Protein S Deficiency | IMAGe Syndrome | Camurati-Engelmann Disease | TARP Syndrome | Spinocerebellar Ataxia Type 27 | Creatine Deficiency Syndrome Due To AGAT Deficiency | Partington Syndrome | Ventricular Septal Defect | Dystonia Musculorum Deformans | Zellweger Syndrome | Hyperferritinemia-cataract Syndrome | Carpal Tunnel Syndrome | Bronchitis | Autoimmune Hemolytic Anemia | Choriocarcinoma | Schamberg Disease | Isobutyryl-CoA Dehydrogenase Deficiency | McCune-Albright Syndrome | Hypertension, Renovascular | Proctitis | Connective Tissue Disorders | Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress | Microcephaly | Retinal Dystrophy | CHOPS Syndrome | Lactose Intolerance | Woodhouse-Sakati Syndrome | Purpura, Thrombotic Thrombocytopenic | Diffuse Palmoplantar Keratoderma | Kawasaki Disease | Cramp Fasciculation Syndrome | Hypocalcemia | Tracheal Disorders | Iron Metabolism Disorders | Familial Hemiplegic Migraine | Hypertensive Nephropathy | Hemimegalencephaly | Syndactyly | Esophageal Carcinoma | Angiosarcoma | Epilepsy, Generalized | Carcinoma, Small Cell | Postaxial Polydactyly | Fundus Albipunctatus | Alveolar Capillary Dysplasia | Pituitary Dwarfism | Asperger Syndrome | Angioimmunoblastic T-cell Lymphoma | Meningioma | Cardiospondylocarpofacial Syndrome | Lymphedema-distichiasis Syndrome | Contact Dermatitis | Steel Syndrome | Basan Syndrome | Small Lymphocytic Lymphoma | Smoldering Myeloma | Malaria | Acrodermatitis Enteropathica | Anthrax | Lymphoma Lymphoblastic | Creatine Deficiency Syndrome | Retinitis Pigmentosa | Situs Inversus | Kernicterus | Spondyloperipheral Dysplasia | Charcot-Marie-Tooth Disease, Type 1A | Renal Oncocytoma | Chronic Myelomonocytic Leukemia | Adenosine Deaminase 2 Deficiency | Multicystic Renal Dysplasia | Dermatofibrosarcoma | Metabolic Syndrome | Dupuytren Disease | Esophageal Motility Disorders | Multifocal Motor Neuropathy | Prader-Willi Syndrome | Nanophthalmos | Esophagitis | Cholangitis | Uterine Leiomyoma | Schistosomiasis Mansoni | Glycogen Storage Disease | Leukoplakia, Oral | Sepiapterin Reductase Deficiency | Basal Cell Nevus Syndrome | ICF Syndrome | Malnutrition | Acute Leukemia | Aldosterone Synthase Deficiency | Infectious Diarrhea | Congenital Disorders Of Glycosylation Type II | Leiomyosarcoma | Cancer, Breast | Acanthosis Nigricans | Patent Foramen Ovale | Panniculitis | Becker Muscular Dystrophy | Fragile X Syndrome | Cancer, Colon | Osteogenesis Imperfecta Type VI | Fowler's Syndrome | Hyperinsulinemia | Agnathia-Otocephaly Complex | Temtamy Preaxial Brachydactyly Syndrome | Coronary Heart Disease | Cerebellar Ataxia, Cayman Type | Chorea | Central Retinal Artery Occlusion | Mitochondrial Myopathy | Empyema | Trichuriasis | Subacute Sclerosing Panencephalitis | Hepatic Veno-occlusive Disease | Gliosarcoma | Congenital Absence Of Vas Deferens | Carbonic Anhydrase VA Deficiency | Hepatorenal Syndrome | Krabbe Disease | Progressive External Ophthalmoplegia | Argininosuccinic Aciduria | Pouchitis | Hypertrophy | Hypercholesterolemia, Familial | Porphyria, Acute Intermittent | Absence Epilepsy | Lesch-Nyhan Syndrome | Cryptorchidism | Membranous Nephropathy | Aneurysm, Abdominal Aortic | Hypercalciuria | MIRAGE Syndrome | Epithelial-myoepithelial Carcinoma | Tyrosinemia Type 2 | Pseudohermaphroditism | Colitis, Lymphocytic | Mucolipidosis Type II | Ehlers-Danlos Syndrome | Prolactinoma | LEOPARD Syndrome | Majeed Syndrome | Amebiasis