Evans Syndrome
Evans Syndrome
About the Disease
Evans' Syndrome, also known as evans syndrome, is related to purpura and thrombocytopenic purpura, autoimmune. An important gene associated with Evans' Syndrome is ADAMTS13 (ADAM Metallopeptidase With Thrombospondin Type 1 Motif 13), and among its related pathways/superpathways are NF-kappaB Signaling and Innate Lymphoid Cells Differentiation. The drugs Tacrolimus and Rituximab have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, bone and liver, and related phenotypes are autoimmune hemolytic anemia and autoimmune thrombocytopenia
Common Targets
LRBA | CTLA4 | G3845 | G6774
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Acromicric Dysplasia | Macular Degeneration | Optic Atrophy 2 | Osteochondroma | Ulcerative Colitis | Pure Red Cell Aplasia | Inflammatory Myofibroblastic Tumor | Vitreoretinal Degeneration, Snowflake Type | Liddle Syndrome | Ghosal Syndrome | Charcot-Marie-Tooth Disease, Type 2 | Goiter, Nodular | Citrullinemia | Cancer, Colon | Cryoglobulinemia | Graves Disease | Congenital Adrenal Hyperplasia 1 | Mannosidase Deficiency Diseases | Dermatitis | Pyruvate Kinase Deficiency | IgA Deficiency | Proopiomelanocortin Deficiency | Cockayne Syndrome | Cholangitis | Ophthalmoplegia | Synpolydactyly | Chondrodysplasia Punctata | Specific Granule Deficiency | Immunoproliferative Disorders | Hypolipoproteinemia | AIDS | Bernard-Soulier Syndrome | Lymphoma, Mantle Cell | Usher Syndrome Type IIC | Hernia, Inguinal | Glycogen Storage Disease Type 1a | X-linked Myotubular Myopathy | Glutaric Aciduria Type 3 | Nanophthalmos | Knobloch Syndrome | Eosinophilic Asthma | Myelitis, Transverse | Thromboembolism | Primary Hyperoxaluria | Retinoblastoma | Vitreoretinopathy, Proliferative | Dysgerminoma | Light Chain Amyloidosis | Carcinoid Tumor | Keratitis-ichthyosis-deafness Syndrome | Osteogenesis Imperfecta Type III | Long QT Syndrome Type 3 | Isobutyryl-CoA Dehydrogenase Deficiency | Meningioma | Crisponi Syndrome | Neuromyotonia | Optic Neuropathy, Anterior Ischemic | Hypermetropia | Pierpont Syndrome | Sengers Syndrome | CHARGE Syndrome | Triple A Syndrome | Spinocerebellar Ataxia Type 1 | Ophthalmia, Sympathetic | Stevens-Johnson Syndrome | Dysthymia | Crigler-Najjar Syndrome | Keratitis | Cutaneous T-cell Lymphoma | Keratopathy | Glioblastoma Multiforme | Dermatomyositis | Tenosynovial Giant Cell Tumor | Hyperlipidemia | Lassa Fever | Low Tension Glaucoma | Pyelonephritis | Antithrombin III Deficiency | Neural Tube Defect | Fibromyalgia | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Fibromuscular Dysplasia | Wagner Disease | Esophagitis, Eosinophilic | Wiedemann-Steiner Syndrome | Hereditary Pyropoikilocytosis | Kearns-Sayre Syndrome | Myoclonic Atonic Epilepsy | Pilomatrix Carcinoma | Tricho-hepato-enteric Syndrome | Cartilage Disorders | Angioedema, Hereditary | Focal Segmental Glomerulosclerosis | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Intestinal Tuberculosis | Distal Myopathy | Peripheral Neuropathy | Colitis | Rhabdomyosarcoma | Osteoarthritis | Feingold Syndrome | Progressive Familial Intrahepatic Cholestasis Type 1 | CEDNIK Syndrome | Panniculitis | Macular Corneal Dystrophy | Spastic Paraplegia Type 7 | Hypertension | Poikiloderma With Neutropenia | Swine Influenza | Familial Pheochromocytoma-paraganglioma | Acrodermatitis Enteropathica | Hypertrophy | Arthropathy | Antiphospholipid Syndrome | Gilbert Syndrome | Gray Platelet Syndrome | 3-hydroxy-3-methylglutaryl-CoA Synthase Deficiency | Osteochondrosis | Hashimoto Thyroiditis | Heart Block | Chediak-Higashi Syndrome | Chiari Malformation Type I | Veno-occlusive Disease | Meleda Disease | Reticular Dysgenesis | Pigment Dispersion Syndrome | Seizures-scoliosis-macrocephaly Syndrome | Muscular Dystrophy | Neurofibroma, Plexiform | Pneumococcal Meningitis | Scapuloperoneal Myopathy, X-linked Dominant | Skin Papilloma | Spinocerebellar Ataxia Type 13 | Astrocytoma, Anaplastic | Infertility, Male | Prader-Willi Syndrome | Borjeson-Forssman-Lehmann Syndrome | Ameloblastoma | Scapuloperoneal Spinal Muscular Atrophy | Spinocerebellar Ataxia Type 8 | Hypersomnia | Pyoderma Gangrenosum | Diabetic Neuropathy | Osmotic Demyelination Syndrome | Joubert Syndrome | Blue Nevus | Split Hand-foot Malformation | Cancer, Kidney | Inflammatory Bowel Disease | Rift Valley Fever | Blepharophimosis Syndrome | Smoldering Myeloma | Fibronectin Glomerulopathy | 3-hydroxy-3-methylglutaric Aciduria | Pemphigus Foliaceus | Alazami Syndrome | Ovarian Hyperstimulation Syndrome | Focal Dermal Hypoplasia | Spinocerebellar Ataxia Type 2 | Hypertension, Renal | Diabetes Mellitus, Transient Neonatal | Keratoconjunctivitis | Kindler Syndrome | Progressive Myoclonic Epilepsy | Glycogen Storage Disease Type 0 | Intestinal Hypomagnesemia 1 | Glycogen Storage Disease Type 1b | Neurofibromatosis Type 2 | Hypopituitarism | Niemann-Pick Disease, Type C | Smith-Lemli-Opitz Syndrome | Xeroderma Pigmentosum Variant Type | Sturge-Weber Syndrome | Dent Disease | Neutrophilia | Corneal Dystrophy | Familial Hypobetalipoproteinemia | Transient Bullous Dermolysis Of The Newborn | Diabetes Type 1 | Renal Failure | Motor Neuron Diseases | Glycogen Storage Disease Type 1 | Proteus Syndrome | Hypertelorism | Pendred Syndrome | Burn-McKeown Syndrome | Sick Sinus Syndrome 1 | Arthritis, Psoriatic | Carcinoma, Merkel Cell | Pyruvate Carboxylase Deficiency Disease | Multiple Sclerosis | Familial Digital Arthropathy-brachydactyly | Multiple System Atrophy | Esophageal Adenocarcinoma | Adenoma, Villous | Ependymoma | Arteriovenous Malformations | Hypoglycemia | Medulloblastoma | Trimethylaminuria | Primary Carnitine Deficiency | Arthritis, Reactive | Non-Langerhans Cell Histiocytosis | Mitochondrial DNA Depletion Syndrome | Malaria | Analgesia | Superficial Spreading Melanoma | Aneurysm, Abdominal Aortic | Metanephric Adenoma | Cleidocranial Dysplasia | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Vitiligo | Binge Eating Disorder | Adenosine Deaminase Deficiency | Spasticity | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 1 | Leiomyosarcoma | Benign Familial Neonatal Convulsions | Paraganglioma | Hemolytic Uremic Syndrome | Cholestasis | Papilloma | Dyggve-Melchior-Clausen Disease | Richter's Syndrome | Acute Myeloid Leukemia | Hyperinsulinism-hyperammonemia Syndrome | Presbyopia | Fuchs Dystrophy | Silicosis | Anuria | Nail Disorder, Nonsyndromic Congenital | Stroke | Galactosemia | MIRAGE Syndrome | Apraxia | Muckle-Wells Syndrome | Ectodermal Dysplasia | Hepatitis B, Chronic | Globozoospermia | Myosin Storage Myopathy | Congenital Mirror Movements | Centronuclear Myopathy | Autosomal Recessive Spastic Paraplegia Type 54 | Insulin Resistance | Prostatitis | Erythematotelangiectatic Rosacea | Wilson's Disease | Micropenis | Hydrocephalus | Lymphedema | Amelanotic Melanoma | Duchenne Muscular Dystrophy | T-cell Leukemia | Congenital Dyserythropoietic Anemia | Glycogen Storage Disease Type 4 | Heterotaxy | Papilledema | Papillon-Lefevre Syndrome | Pineoblastoma | Danon Disease | Dyslipidemia | Hyperinsulinemic Hypoglycemia | Carpenter Syndrome | Tardive Dyskinesia | Periventricular Leukomalacia | Krabbe Disease | Delayed Sleep Phase Syndrome | Congenital Disorders Of Glycosylation | Hypertensive Nephropathy | Acromegaly | Alopecia Areata | Nephroblastoma | Ocular Surface Squamous Neoplasia | Torticollis | Lissencephaly 2 | Allan-Herndon-Dudley Syndrome | Familial Isolated Hyperparathyroidism | Pregnancy, Ectopic | Lichen Planus | Myositis | Neurofibroma | Rubeosis Iridis | Neuromuscular Disorders | 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