Disease

Niemann-Pick Disease

About the Disease
Niemann-Pick Disease, also known as sphingomyelin/cholesterol lipidosis, is related to niemann-pick disease, type b and niemann-pick disease, type a, and has symptoms including constipation, vomiting and muscle weakness. An important gene associated with Niemann-Pick Disease is SMPD1 (Sphingomyelin Phosphodiesterase 1), and among its related pathways/superpathways are Ebola virus infection in host and Sphingolipid metabolism. The drugs Miglustat and Anti-HIV Agents have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, spleen and liver, and related phenotypes are no effect and no effect

Common Targets
ABL1 | DNA-Directed DNA Polymerase Complex | CRBN | LRRK2 | CLN3 | UGCG | SMPD1 | ESR2 | Sphingomyelin phosphodiesterase (nonspecified subtype) | G4780 | G4137 | DNA Topoisomerase II (nonspecified subtype) | OGA | S1PR5 | G2099 | G196 | HCAR2 | NPC1 | NMDA receptor | NPC2

疾病靶点研报
Niemann-Pick Disease

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