Disease

Fibrodysplasia Ossificans Progressiva

About the Disease
Fibrodysplasia Ossificans Progressiva, also known as myositis ossificans progressiva, is related to osseous heteroplasia, progressive and ankylosis. An important gene associated with Fibrodysplasia Ossificans Progressiva is ACVR1 (Activin A Receptor Type 1), and among its related pathways/superpathways are ERK Signaling and Signal Transduction. The drugs Tin Fluorides and Antibodies, Monoclonal have been mentioned in the context of this disorder. Affiliated tissues include bone, skeletal muscle and skin, and related phenotypes are abnormal vertebral morphology and spinal rigidity

Common Targets
TFRC | MDK | TGFBR1 | INHBA | ACVR1 | ACVRL1 | RET | ACVR1B | BMP6 | FYN | G238 | RARG | BMPR1A | ABL1 | BMPR1B | RIPK2

疾病靶点研报
Fibrodysplasia Ossificans Progressiva

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