Cannabis Abuse

About the Disease
Cannabis Abuse, also known as marijuana abuse, is related to polysubstance abuse and drug psychosis. An important gene associated with Cannabis Abuse is CNR1 (Cannabinoid Receptor 1), and among its related pathways/superpathways are Signal Transduction and GPCR downstream signalling. The drugs Fluoxetine and Topiramate have been mentioned in the context of this disorder. Affiliated tissues include brain, eye and spinal cord, and related phenotypes are no effect and no effect

Common Targets
CYSLTR1 | CNR1 | COMT | HTR1A | Alpha-2 Adrenergic receptors (nonspecified subtype) | MGLL | GABA(A) receptor | TBC1D22A | NRG1 | PDE10A | ANKK1 | SEC24D | ARHGEF33 | Acetylcholine Receptors (Nicotinic) (nAChR) (nonspecified subtype) | CHRNA7 | LOC101927967 | NAT1 | Nicotinic alpha3beta4 Receptor | Nicotinic alpha4beta2 receptor | CSMD1 | HTR2A | SLC6A4 | RET | NPY | CCAR1 | DOCK5 | FAAH | MED15 | BDNF-AS | SCN9A | CHRNA3 | BPTF | MIF | HTR2C | LOC105374535 | UNC119B | RBPMS | Cannabinoid receptor (nonspecified subtype) | DRD3 | PDE11A | AFF3 | SLC6A1 | G7099 | GPR55 | RARG | alpha-6 beta-2 Nicotinic receptor | SLC35G1 | CHRNB2 | STEAP3 | TAAR1 | DMD | BDNF | CNR2 | CTNND2 | Phosphodiesterase IV (PDE4) (nonspecified subtype) | CHRNA5 | G207 | CIBAR1-DT | DRD2 | C17orf58 | COL23A1

Note: If you'd like to get a target analysis report for Cannabis Abuse, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Cannabis Abuse at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Craniopharyngioma | Cholestasis, Intrahepatic | Intracranial Hypertension | Omenn Syndrome | Acromesomelic Dysplasia | Leri-Weill Dyschondrosteosis | Rhinitis | Inflammatory Bowel Disease | Schaaf-Yang Syndrome | Cocaine-Related Disorders | Xeroderma Pigmentosum Variant Type | Cerebellar Ataxia, Cayman Type | CHARGE Syndrome | Multiple System Atrophy | Long-chain 3-hydroxyacyl-coenzyme A Dehydrogenase Deficiency | Pantothenate Kinase-associated Neurodegeneration | Leber Congenital Amaurosis | Poretti-Boltshauser Syndrome | Ganglioglioma | Apparent Mineralocorticoid Excess Syndrome | Congenital Torticollis | Coronary Heart Disease | Congenital Disorders Of Glycosylation | Lipid Storage Myopathy | Hypohidrotic Ectodermal Dysplasia | Congenital Afibrinogenemia | Warsaw Breakage Syndrome | Sturge-Weber Syndrome | Leukoplakia, Oral | Hemangioendothelioma | Cholelithiasis | Spinal Muscular Atrophy Type 2 | Vaginitis | Guillain-Barre Syndrome | Lupus Erythematosus | Beckwith-Wiedemann Syndrome | Paternal Uniparental Disomy Of Chromosome 14 | Usher Syndrome Type I | Hypodontia | Lymphangioma | Erythema Multiforme | Glycogen Storage Disease Type 1a | Phenylketonuria II | Myofibromatosis | Gray Platelet Syndrome | Carcinoid Tumor | Burn-McKeown Syndrome | Mucolipidosis Type II | Hyperuricemic Nephropathy, Familial Juvenile | ICF Syndrome | Dystonia Musculorum Deformans | Focal Segmental Glomerulosclerosis | Familial Hypertrophic Cardiomyopathy | Pure Autonomic Failure | Waardenburg Syndrome Type 2A | Alazami Syndrome | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Vasculitis | Loeys-Dietz Syndrome Type 4 | Spinocerebellar Ataxia Type 15 | Palmoplantar Keratoderma | Tendinopathy | Congenital Aniridia | Cone Dystrophy | Contact Dermatitis | Schwartz-Jampel-Aberfeld Syndrome | Kallmann Syndrome | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | Gilbert Syndrome | Primary Aldosteronism | Hypertension | Ocular Hypertension | Amyotrophic Lateral Sclerosis, Juvenile | Sitosterolemia | Celiac Disease | Spinocerebellar Ataxia Type 40 | Agammaglobulinemia | Nephrocalcinosis | VEXAS Syndrome | Astrocytoma, Anaplastic | Tangier Disease | Nephropathy | Prolidase Deficiency | Fundus Albipunctatus | Acne Vulgaris | Early Infantile Epileptic Encephalopathy 1 | Walker-Warburg Syndrome | Senior-Loken Syndrome | Non-proliferative Diabetic Retinopathy | Vascular Calcification | Mandibuloacral Dysplasia With Type A Lipodystrophy | Major Depression | Osteomalacia | Limb Girdle Muscular Dystrophy | Heterotopic Ossification | Gangliosidosis | Atrial Septal Defect | Rhabdomyosarcoma, Alveolar | Mycosis Fungoides | Neurofibromatosis-Noonan Syndrome | Pyoderma Gangrenosum | Familial Male-limited Precocious Puberty | Spinocerebellar Ataxia Type 16 | Osteomyelitis | Echinococcosis | Exocrine Pancreatic Insufficiency | Synovitis | Familial Hyperaldosteronism | Asplenia | Hyperbilirubinemia, Neonatal | Tibial Muscular Dystrophy | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Microvillus Inclusion Disease | Macrodactyly | Pelvic Inflammatory Disease | Benign Familial Neonatal Convulsions | Angioedema | Fibromuscular Dysplasia | Majeed Syndrome | Peroxisomal Disorder | Familial Isolated Hyperparathyroidism | Hypotrichosis Simplex | Metachondromatosis | Ectrodactyly | Autonomic Neuropathy | Otosclerosis | Ameloblastoma | Chylothorax, Congenital | Spinocerebellar Ataxia Type 42 | Charcot-Marie-Tooth Disease Type 4D | Arthritis, Gouty | Non-small Cell Lung Cancer | Nemaline Myopathy | Larsen Syndrome | Dystrophy, Cone-rod | Carey-Fineman-Ziter Syndrome | Adenoid Cystic Carcinoma | Double Outlet Right Ventricle | Hereditary Hemorrhagic Telangiectasia Type 2 | Zellweger Syndrome | Usher Syndrome | Tardive Dyskinesia | Intestinal Pseudo-obstruction | Osteogenesis Imperfecta | Neonatal Progeroid Syndrome | Acral Lentiginous Melanoma | Medulloblastoma | Loeys-Dietz Syndrome | Neurocutaneous Melanocytosis | Neurodegeneration Due To Cerebral Folate Transport Deficiency | Syncope | Congenital Muscular Dystrophy | Depression | Still Disease | Distal Myopathy 2 | Cholesteryl Ester Storage Disease | Fibrodysplasia Ossificans Progressiva | Epiphyseal Chondrodysplasia, Miura Type | Sclerosing Cholangitis | Gastrointestinal Disorders | Carbonic Anhydrase VA Deficiency | Urofacial Syndrome | Aneurysm, Abdominal Aortic | Benign Hereditary Chorea | Alopecia | Proteasome-associated Autoinflammatory Syndrome 2 | Hereditary Multiple Exostoses | Adenoma, Villous | LMNA-related Congenital Muscular Dystrophy | Hypercalcemia | Cramp Fasciculation Syndrome | Hypercalciuria | Autoimmune Disease | Anovulation | Multifocal Motor Neuropathy | Papillon-Lefevre Syndrome | Opisthorchiasis | Splenomegaly | Dermatofibrosarcoma | Lichen Sclerosus | Generalized Epilepsy And Paroxysmal Dyskinesia | Kashin-Beck Disease | Anterior Segment Dysgenesis | Richter's Syndrome | H Syndrome | Absence Epilepsy | Filariasis | Sick Sinus Syndrome | Charcot-Marie-Tooth Disease, Type 2A | Cystitis, Interstitial | Lewy Body Dementia | Pelizaeus-Merzbacher Disease | Oguchi Disease-2 | Takenouchi-Kosaki Syndrome | Seizures-scoliosis-macrocephaly Syndrome | Myositis, Focal | Aplasia Cutis Congenita | Peyronie's Disease | Strabismus | Alpha-thalassemia Myelodysplasia Syndrome | B-cell Prolymphocytic Leukemia | Glycogen Storage Disease Type 5 | Hypotonia-cystinuria Syndrome | Blau Syndrome | Microcephaly, Seizures, And Developmental Delay | Osteoglophonic Dysplasia | WAGR Syndrome | Spina Bifida | Pendred Syndrome | Adenomyosis | Osteogenesis Imperfecta Type IV | Microphthalmia, Syndromic 7 | Neuroendocrine Cancer | Rheumatoid Arthritis | Spinocerebellar Ataxia | Chorea-acanthocytosis | Blepharoconjunctivitis | Coenzyme Q10 Deficiency | Pulmonary Stenosis | Werner's Syndrome | Fontaine Progeroid Syndrome | Wolfram Syndrome | VACTERL Association | Bone Marrow Necrosis | Waardenburg Syndrome Type 2E | Presbyopia | Tic Disorder | Pityriasis Rubra Pilaris | Asthma, Nocturnal | Lung Diseases | Aicardi-Goutieres Syndrome | Hyperekplexia | Keratoconus | Sclerocornea | Dyslipidemia | Persistent Fetal Circulation | Cerebral Amyloid Angiopathy | Von Hippel-Lindau Disease | Arteriosclerosis | Primary Pigmented Nodular Adrenocortical Disease | Glanzmann Thrombasthenia | 17-beta-hydroxysteroid Dehydrogenase X Deficiency | Osteogenesis Imperfecta Type V | Pneumothorax | Currarino Syndrome | Sengers Syndrome | Hepatic Steatosis | Necrotizing Autoimmune Myopathy | Diamond-Blackfan Anemia | Coffin-Siris Syndrome | Sickle Cell Anemia | Gyrate Atrophy Of The Choroid And Retina | Hyperinsulinemia | Tetanus | McCune-Albright Syndrome | Cri-du-chat Syndrome | COACH Syndrome | Pemphigus Foliaceus | Schwannomatosis | Acute Coronary Syndrome | Perivascular Epithelioid Cell Tumor | Congenital Sodium Diarrhea | Chronic Kidney Disease | Granular Corneal Dystrophy Type 1 | Nemaline Myopathy 8 | Congenital Absence Of Vas Deferens | Juvenile Polyposis | Diffuse Palmoplantar Keratoderma | Pyruvate Kinase Deficiency | L-2-Hydroxyglutaric Aciduria | Vitamin K Deficiency | Prader-Willi Syndrome | Relapsing Polychondritis | Esthesioneuroblastoma | Lissencephaly 2 | Arterial Tortuosity Syndrome | Pearson Syndrome | Sclerosteosis | Schizophrenia, Paranoid | Hyperlipidemia, Familial Combined | Waardenburg Syndrome Type 4 | Allan-Herndon-Dudley Syndrome | McLeod Syndrome | Cantu Syndrome | Myositis | Eiken Syndrome | Fanconi Anemia | Jawad Syndrome | Carcinoma, Merkel Cell | Gingivitis | Cluster Headache | Giant Axonal Neuropathy | Hartsfield Syndrome | Iron Overload | Peritonitis | Osmotic Demyelination Syndrome | Pemphigoid | Renal Hypouricemia | Progressive Familial Intrahepatic Cholestasis Type 3 | Christianson Syndrome | Hypoproteinemia, Hypercatabolic | Enhanced S-cone Syndrome | Genee-Wiedemann Syndrome | AIDS | Glycogen Storage Disease Type 0, Muscle | Hereditary Folate Malabsorption | Teratozoospermia | Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis | Aldosterone Deficiency | Kearns-Sayre Syndrome | Congenital Disorders Of Glycosylation Type II | Macular Degeneration | Distal Myopathy | Netherton Syndrome | Synpolydactyly | IgA Deficiency | Traboulsi Syndrome | Acrodermatitis | Lymphedema | Neurofibroma | Proximal Symphalangism | Hyperparathyroidism, Primary | Stroke, Hemorrhagic | T-cell Prolymphocytic Leukemia | Congenital Dyserythropoietic Anemia Type 1 | Angioimmunoblastic T-cell Lymphoma | Acne | Carotid Artery Disease | Restless Legs Syndrome | Sporadic Hemiplegic Migraine | Transthyretin-related Amyloidosis | Common Cold | Nail Disorder, Nonsyndromic Congenital | Chondrodysplasia Punctata | Skin Carcinoma | Neuroleptic Malignant Syndrome | Meningitis | Vertebrobasilar Insufficiency | Neurofibromatosis Type 1 | Schizotypal Personality Disorder | Carney-Stratakis Syndrome | Generalized Epilepsy With Febrile Seizures Plus | Fuchs Dystrophy | Hyperkalemic Periodic Paralysis | Spinocerebellar Ataxia Type 12 | Growth Hormone Excess | Facioscapulohumeral Muscular Dystrophy Type 1 | Steel Syndrome | MIRAGE Syndrome | Cervicitis | Choroideremia | Pemphigus | Wieacker-Wolff Syndrome | Autism Spectrum Disorders | DiGeorge Syndrome | Leishmaniasis, Visceral | Huntington's Disease | Silicosis | Pseudohermaphroditism | Delirium | Cancer, Brain | Histoplasmosis | Aspartylglycosaminuria | Acrocallosal Syndrome | Methemoglobinemia | Spinocerebellar Ataxia Type 17 | Thymoma, Malignant | Epithelial-myoepithelial Carcinoma | Stuve-Wiedemann Syndrome | Antley-Bixler Syndrome | Autoimmune Polyendocrinopathy Syndrome Type I | KBG Syndrome | Sleep Apnea, Obstructive | Congenital Myopathy | Pycnodysostosis | Spinocerebellar Ataxia Type 6 | Tenosynovial Giant Cell Tumor | Familial Partial Lipodystrophy | Craniometaphyseal Dysplasia | Spinal Cord Diseases | Discoid Lupus Erythematosus | Gastritis | Eosinophilic Asthma | 3-methylglutaconic Aciduria Type IV | Chordoma | Nestor-Guillermo Progeria Syndrome | Parkinson Disease 6, Autosomal Recessive Early-onset | Superficial Spreading Melanoma | Campomelic Dysplasia | Pyruvate Decarboxylase Deficiency | Rhabdomyosarcoma, Embryonal | Epidermolysis Bullosa Simplex, Dowling-Meara Type | GAPO Syndrome | Robinow Syndrome | Kohlschutter-Tonz Syndrome | Papulopustular Rosacea | Placenta Previa | Spondylolisthesis | Measles | Thanatophoric Dysplasia Type 1