Disease

Cannabis Abuse

About the Disease
Cannabis Abuse, also known as marijuana abuse, is related to polysubstance abuse and drug psychosis. An important gene associated with Cannabis Abuse is CNR1 (Cannabinoid Receptor 1), and among its related pathways/superpathways are Signal Transduction and GPCR downstream signalling. The drugs Fluoxetine and Topiramate have been mentioned in the context of this disorder. Affiliated tissues include brain, eye and spinal cord, and related phenotypes are no effect and no effect

Common Targets
CYSLTR1 | CNR1 | COMT | HTR1A | Alpha-2 Adrenergic receptors (nonspecified subtype) | MGLL | GABA(A) receptor | TBC1D22A | NRG1 | PDE10A | ANKK1 | SEC24D | ARHGEF33 | Acetylcholine Receptors (Nicotinic) (nAChR) (nonspecified subtype) | CHRNA7 | LOC101927967 | NAT1 | Nicotinic alpha3beta4 Receptor | Nicotinic alpha4beta2 receptor | CSMD1 | HTR2A | SLC6A4 | RET | NPY | CCAR1 | DOCK5 | FAAH | MED15 | BDNF-AS | SCN9A | CHRNA3 | BPTF | MIF | HTR2C | LOC105374535 | UNC119B | RBPMS | Cannabinoid receptor (nonspecified subtype) | DRD3 | PDE11A | AFF3 | SLC6A1 | G7099 | GPR55 | RARG | alpha-6 beta-2 Nicotinic receptor | SLC35G1 | CHRNB2 | STEAP3 | TAAR1 | DMD | BDNF | CNR2 | CTNND2 | Phosphodiesterase IV (PDE4) (nonspecified subtype) | CHRNA5 | G207 | CIBAR1-DT | DRD2 | C17orf58 | COL23A1

疾病靶点研报
Cannabis Abuse

Note: If you'd like to get a target analysis report for Cannabis Abuse, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Cannabis Abuse at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Lewy Body Dementia | Congenital Adrenal Hyperplasia 1 | Okihiro Syndrome | Pseudohermaphroditism | Chorioretinitis | Smith-Lemli-Opitz Syndrome | Congenital Tufting Enteropathy | Cabezas Syndrome | Temtamy Preaxial Brachydactyly Syndrome | Salla Disease | Diabetic Nephropathy | Usher Syndrome Type I | Blepharospasm | Bloom Syndrome | Dysferlinopathy | Purpura | Vulvovaginitis | Pseudoexfoliation Syndrome | Hemorrhage | Vertebrobasilar Insufficiency | Bronchitis | Familial Pheochromocytoma-paraganglioma | Astrocytoma | Hyperuricemic Nephropathy, Familial Juvenile | Calcium Pyrophosphate Deposition Disease | Pyoderma Gangrenosum | Primary Hyperoxaluria | Alpha-mannosidosis | Smith-Kingsmore Syndrome | Chylomicron Retention Disease | Uremic Pruritus | N-acetylglutamate Synthase Deficiency | Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form | Aldosterone Deficiency | Multiple Epiphyseal Dysplasia | Autosomal Recessive Spastic Paraplegia Type 75 | Hepatitis | DiGeorge Syndrome | Lymphoproliferative Disorders | Cholangitis | Carey-Fineman-Ziter Syndrome | Diamond-Blackfan Anemia | Pneumonia, Viral | VACTERL/VATER Association | Cold-induced Sweating Syndrome | Multiple Sclerosis, Secondary Progressive | Arterial Tortuosity Syndrome | Distal Myopathy 2 | Lymphedema-distichiasis Syndrome | Pseudohypoparathyroidism Type 2 | Primary Progressive Nonfluent Aphasia | Hypotrichosis Simplex | Leukemia | Primary Hyperoxaluria Type 3 | Oral Lichen Planus | Cutaneous Mastocytosis | Lesch-Nyhan Syndrome | Osteoarthritis | Systemic Lupus Erythematosus | Hypokalemia | Tuberculous Meningitis | Herpes Simplex Dermatitis | Creatine Deficiency Syndrome Due To AGAT Deficiency | Spasticity | Mitochondrial Cytopathy | Primary Sclerosing Cholangitis | Papillon-Lefevre Syndrome | Pulmonary Alveolar Microlithiasis | Primary Ovarian Insufficiency | Crisponi Syndrome | Optic Nerve Diseases | Wilson's Disease | Corneal Neovascularization | Spinocerebellar Ataxia Type 31 | Bruck Syndrome | Angiodysplasia | Hepatitis A | Spinocerebellar Ataxia Type 23 | Pseudo-pseudohypoparathyroidism | Hydronephrosis | Obesity | Aarskog-Scott Syndrome | Schwannomatosis | Senior-Loken Syndrome | Babesiosis | IgA Nephropathy | Narcolepsy | Central Retinal Artery Occlusion | Polycystic Liver | REM Sleep Behavior Disorder | Keratoconus | Maternally Inherited Diabetes And Deafness | Sulfite Oxidase Deficiency | Arthritis, Psoriatic | Microtia | Congenital Stationary Night Blindness | Hydrolethalus Syndrome | Ocular Albinism Type 1 | Camurati-Engelmann Disease | Gastritis | Dermatitis Herpetiformis | Basal Ganglia Cerebrovascular Disease | Hermansky-Pudlak Syndrome | Metachromatic Leukodystrophy | Raine Syndrome | Hypogonadism | 17-beta-hydroxysteroid Dehydrogenase X Deficiency | Pigment Dispersion Syndrome | Pemphigus Foliaceus | Seborrheic Dermatitis | Veno-occlusive Disease | HELLP Syndrome | Hidradenitis Suppurativa | Anosmia, Congenital | Diabetic Neuropathy | Metaphyseal Chondrodysplasia, Schmid Type | Smith-Magenis Syndrome | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Stargardt Disease | Dyslipidemia | Dermatomyositis | Thyrotoxic Periodic Paralysis | Panniculitis | Blue Rubber Bleb Nevus Syndrome | Anti-NMDA Receptor Encephalitis | Chronic Mucocutaneous Candidiasis | Hartnup Disease | Metabolic Diseases | Myoclonic Epilepsy With Ragged Red Fibers | Sialidosis Type I | Anovulation | Fahr Disease | Specific Granule Deficiency | GATA2 Deficiency | Cousin Syndrome | Asthma, Nocturnal | HUPRA Syndrome | Leber Hereditary Optic Neuropathy | Nance-Horan Syndrome | Liver Diseases | Acrodermatitis Enteropathica | Diabetes Gestational | Dystonia Musculorum Deformans | Rett Syndrome | Papulopustular Rosacea | Alopecia Areata | Premature Ejaculation | Lymphomatoid Granulomatosis | Oguchi Disease-2 | Holoprosencephaly | Congenital Sodium Diarrhea | Juvenile Polyposis | Meckel-Gruber Syndrome | Psoriasis | Agranulocytosis | Angelman Syndrome | Epidermolysis Bullosa Acquisita | Autoimmune Autonomic Ganglionopathy | Schizophrenia | Shock, Cardiogenic | Exostoses | Non-epidermolytic Palmoplantar Keratoderma | Carpal Tunnel Syndrome | Irritable Bowel Syndrome | Waardenburg Syndrome Type 4A | Mannosidase Deficiency Diseases | Cat Eye Syndrome | Diffuse Mesangial Sclerosis | Oculocutaneous Albinism Type 2 | Diffuse Intrinsic Pontine Glioma | Niemann-Pick Disease, Type B | Brenner Tumor | Larsen Syndrome | Leukoplakia | Multicystic Renal Dysplasia | Charcot-Marie-Tooth Disease Type 2T | Low Tension Glaucoma | Hypercholesterolemia | Osteochondroma | Atrioventricular Septal Defect | Meningococcal Infections | Craniosynostosis | PHARC Syndrome | Multiple Hamartoma Syndrome | Blastomycosis | Hartsfield Syndrome | Disseminated Superficial Actinic Porokeratosis | Priapism | High Molecular Weight Kininogen Deficiency | Prediabetes | Congenital Primary Aphakia | Basan Syndrome | Adams-Oliver Syndrome | PASLI Disease | Melanocytic Nevus | Congestive Heart Failure | Purpura, Thrombotic Thrombocytopenic | Osmotic Demyelination Syndrome | Multicentric Carpotarsal Osteolysis Syndrome | Chromosome 16p11.2 Deletion Syndrome | Lymphoma, Mantle Cell | Vitreoretinal Degeneration, Snowflake Type | Gitelman Syndrome | Skin Fragility-woolly Hair Syndrome | Subacute Sclerosing Panencephalitis | Fukuyama Congenital Muscular Dystrophy | Gigantism | Non-bullous Congenital Ichthyosiform Erythroderma | Pontocerebellar Hypoplasia | Corneal Edema | ADNP Syndrome | Spondyloperipheral Dysplasia | Neurofibroma | Cancer, Breast | Cerebellar Ataxia, Cayman Type | Neurofibromatosis Type 2 | Restless Legs Syndrome | Mabry Syndrome | Actinomycetoma | Reye Syndrome | Eczema | Pituitary Disorders | Gastroenteritis, Eosinophilic | Spinocerebellar Ataxia Type 3 | Homocystinuria | Muscular Dystrophy | Pseudohypoparathyroidism Type 1B | Tinea | Granular Corneal Dystrophy Type 1 | Pancytopenia | Autoimmune Polyendocrine Syndrome | Ehlers-Danlos Syndrome With Progressive Kyphoscoliosis, Myopathy, And Hearing Loss | Nephrotic Syndrome Type 1 | Glycogen Storage Disease | Renal Hypomagnesemia 3 | Pneumoconiosis | Hyperammonemia | Major Depression | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Acute Leukemia | Echinococcosis | Cholecystitis | Leishmaniasis, Visceral | Hypobetalipoproteinemias | Neurofibroma, Plexiform | Multiple System Atrophy | Histiocytic Sarcoma | Infertility, Male | Infantile Neuroaxonal Dystrophy | Pyruvate Kinase Deficiency | Retinal Dystrophy, Early-onset Severe | Rift Valley Fever | Chiari Malformation Type I | Polycystic Ovary Syndrome | Congenital Absence Of Vas Deferens | Axenfeld-Rieger Syndrome | Hyperferritinemia-cataract Syndrome | Cirrhosis | Atopic Dermatitis | Adrenomyeloneuropathy | Shwachman-Bodian-Diamond Syndrome | Esophageal Adenocarcinoma | MIRAGE Syndrome | Agnathia-Otocephaly Complex | Schizencephaly | Myofibrillar Myopathy | Choroiditis | Epicondylitis | Hypoglycemia | Plasmacytoma | Myelomeningocele | Cryopyrin-associated Periodic Syndromes | Cushing Syndrome | Neuroleptic Malignant Syndrome | Cataract | Thrombophilia | Polymyositis | Botulism | Arts Syndrome | Cholesteryl Ester Storage Disease | Ligneous Conjunctivitis | Eiken Syndrome | Extramammary Paget's Disease | Hereditary Spastic Paraplegia | Barakat Syndrome | Graves Disease | Noonan Syndrome | Unverricht-Lundborg Syndrome | Pterygium | Nephrocalcinosis | Hyperkeratosis | Myositis, Focal | Anodontia | Limb Girdle Muscular Dystrophy | Rosacea | Primary Torsion Dystonia | Heterotopic Ossification | Spondylosis | Genitopatellar Syndrome | Dental Caries | Menkes Disease | Congenital Disorders Of Glycosylation Type II | Portal Vein Thrombosis | Alpers Syndrome | Anxiety Disorders | Hemoglobinopathies | Basal Ganglia Disease, Biotin-responsive | Adenoma, Villous | Chronic Lymphocytic Leukemia | Peroxisomal Disorder | Chronic Granulomatous Disease | Intestinal Pseudo-obstruction | Alkaptonuria | L-2-Hydroxyglutaric Aciduria | Chorea | Carcinoma, Squamous Cell | Jalili Syndrome | Nanophthalmos | Greig Cephalopolysyndactyly Syndrome | Arthritis | T-cell Chronic Lymphocytic Leukemia | Scabies | Farber Disease | Spinocerebellar Ataxia Type 17 | Alveolar Capillary Dysplasia | Giant Cell Arteritis | Systemic Mastocytosis | Bethlem Myopathy | Snyder-Robinson Syndrome | Occipital Neuralgia | Hemangioma | NDH Syndrome | Dwarfism | Familial Partial Lipodystrophy | Sarcoidosis | Hereditary Sensory And Autonomic Neuropathy | Hyperprolactinemia | Allan-Herndon-Dudley Syndrome | Joubert Syndrome | Macular Corneal Dystrophy | Uveitis, Anterior | Twin-to-twin Transfusion Syndrome | Congenital Muscular Dystrophy | Sensory Neuropathy | Hyperoxaluria | Carbohydrate Metabolism Disorders | Dupuytren Disease | Pleural Tuberculosis | Arteriovenous Malformations | Carcinoid Tumor | Primary Pigmented Nodular Adrenocortical Disease | Polyomavirus Nephropathy | Osteogenesis Imperfecta Type VI | Combined Pituitary Hormone Deficiency | Rothmund-Thomson Syndrome | Amebiasis | GAPO Syndrome | Absence Epilepsy | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Succinic Semialdehyde Dehydrogenase Deficiency | Learning Disability | Acromegaly | Poirier-Bienvenu Neurodevelopmental Syndrome | Cerebral Cavernous Malformations | Otosclerosis | Sclerocornea | Van Der Knaap Disease | Osteoporosis, Postmenopausal | Barrett Esophagus | Multisystemic Smooth Muscle Dysfunction Syndrome | Fibrosarcoma | Cornelia De Lange Syndrome | Mumps | Myasthenia | Hypopituitarism | Ameloblastic Carcinoma | Pupil Disorders | Hyperbilirubinemia | Glaucoma | Hereditary Elliptocytosis | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | 3-methylglutaconic Aciduria Type IV | Astrocytoma, Anaplastic | Greenberg Dysplasia | Wolfram Syndrome 2 | Tendinitis | Plasma Cell Leukemia | Periventricular Nodular Heterotopia | Glycogen Storage Disease Type 0, Muscle | Meesmann Corneal Dystrophy | Hypospadias | Encephalocele | DICER1 Syndrome | Mitochondrial Encephalomyopathy | Anterior Segment Dysgenesis | DNA Ligase IV Deficiency | Diabetes Insipidus | Distal Spinal Muscular Atrophy | Waardenburg Syndrome Type 1 | Glaucomatocyclitic Crisis