Tietze Syndrome

About the Disease
Tietz Albinism-Deafness Syndrome, also known as tietz syndrome, is related to sensorineural hearing loss and albinism. An important gene associated with Tietz Albinism-Deafness Syndrome is MITF (Melanocyte Inducing Transcription Factor), and among its related pathways/superpathways are Neural crest differentiation and Development EPO-induced Jak-STAT pathway. Affiliated tissues include skin, eye and retina, and related phenotypes are hearing impairment and hypopigmentation of hair

Common Targets
MC1R

Note: If you'd like to get a target analysis report for Tietze Syndrome, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Tietze Syndrome at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Diabetes Gestational | D-2-Hydroxyglutaric Aciduria | Hyperuricemia | Metanephric Adenoma | Aldosteronism | Chronic Myeloid Leukemia | Rett Syndrome | Corneal Edema | Spinocerebellar Ataxia Type 28 | Lathosterolosis | Esotropia | Neuromyelitis Optica | Encephalocele | X-linked Myotubular Myopathy | Teratozoospermia | Panuveitis | Epithelioid Hemangioma | LMNA-related Congenital Muscular Dystrophy | Low Phospholipid Associated Cholelithiasis | Cerebrovascular Disorders | 3C Syndrome | Renpenning Syndrome | Schaaf-Yang Syndrome | Genitopatellar Syndrome | Chronic Inflammatory Demyelinating Polyneuropathy | Coloboma | Hyperekplexia | Leukodystrophies | Erythrokeratodermia Variabilis | Actinomycetoma | Oligodendroglioma | Erythema Nodosum | Immunoproliferative Disorders | Porphyria, Acute Intermittent | Ischemia | Osteochondrosis | Early Infantile Epileptic Encephalopathy 28 | Stroke, Ischemic | Hypohidrotic Ectodermal Dysplasia, X-linked | DOCK8 Immunodeficiency Syndrome | Acquired Partial Lipodystrophy | Carcinoma In Situ | Non-proliferative Diabetic Retinopathy | Hyperinsulinemic Hypoglycemia | Cleidocranial Dysplasia | Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form | Neurodevelopmental Disorders | Hypertensive Nephropathy | Chondrodysplasia Punctata | Dysfibrinogenemia | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Snyder-Robinson Syndrome | Chordoid Glioma | Cutaneous Lupus Erythematosus | Riboflavin Transporter Deficiency Neuronopathy | Congenital Adrenal Hyperplasia 1 | Osteopetrosis | Acral Lentiginous Melanoma | Encephalopathy, Glycine | Swine Influenza | Fibrosarcoma | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Gitelman Syndrome | Charcot-Marie-Tooth Disease Type 2D | Fucosidosis | Neurotoxicity | Cardiofaciocutaneous Syndrome | Autoimmune Hemolytic Anemia | Uremia | Congenital Mirror Movements | Hypothalamic Obesity | Lyme Disease | Spondylo-ocular Syndrome | Thyroid Dyshormonogenesis | Myhre Syndrome | Colitis, Lymphocytic | Adenoma, Pituitary | Absence Epilepsy | Schizencephaly | Seminoma | Sepiapterin Reductase Deficiency | Acromesomelic Dysplasia | Frontotemporal Dementia | CHOPS Syndrome | Central Retinal Artery Occlusion | Primary Carnitine Deficiency | Chanarin-Dorfman Syndrome | Lymphoma, B-cell | Blood Protein Disorders | Hypermethioninemia | Myofibrillar Myopathy | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Anti-glomerular Basement Membrane Disease | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Benign Familial Infantile Seizures | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Iron Deficiency Anemia | Anterior Segment Dysgenesis | Uremic Pruritus | Hereditary Neuropathy With Liability To Pressure Palsies | Leukoencephalopathy, Progressive Multifocal | Pityriasis Rubra Pilaris | Intellectual Disability, Autosomal Dominant 5 | Noonan Syndrome | Opisthorchiasis | Nephroblastoma | Myasthenia Gravis | Hemorrhagic Disorders | Anxiety Disorders | Hypertensive Retinopathy | TARP Syndrome | Myelomeningocele | Restless Legs Syndrome | Sensorineural Hearing Loss | Mitochondrial DNA Depletion Syndrome | MIRAGE Syndrome | Odonto-onycho-dermal Dysplasia | Lennox-Gastaut Syndrome | Chronic Beryllium Disease | Fetal Alcohol Syndrome | Hypercholesterolemia | Long-chain 3-hydroxyacyl-coenzyme A Dehydrogenase Deficiency | Dysthymia | Primary Progressive Nonfluent Aphasia | Pyoderma Gangrenosum | Multiple Hamartoma Syndrome | Astrocytoma, Anaplastic | Nemaline Myopathy 10 | Cryopyrin-associated Periodic Syndromes | Schizoaffective Disorder | Myotonia | Chronic Granulomatous Disease | Spinocerebellar Ataxia Type 15 | Common Variable Immunodeficiency | Pheochromocytoma | Congenital Primary Aphakia | Hypersomnia | Plasma Cell Dyscrasia | Spinocerebellar Ataxia Type 23 | DRESS Syndrome | Hereditary Elliptocytosis | Periventricular Leukomalacia | AIDS Dementia Complex | Holt-Oram Syndrome | FG Syndrome | Ectodermal Dysplasia | Nephrotic Syndrome Type 1 | Osmotic Demyelination Syndrome | Osteogenesis Imperfecta Type IV | Chronic Lymphocytic Leukemia | Myelitis, Transverse | Proteasome-associated Autoinflammatory Syndrome 2 | Chloridorrhea, Congenital | Keratoacanthoma | Papillon-Lefevre Syndrome | Loeys-Dietz Syndrome | Renal-hepatic-pancreatic Dysplasia | Spastic Paraplegia Type 7 | Cryptorchidism | Synpolydactyly | Usher Syndrome Type IIC | Creatine Deficiency Syndrome | Lichen Planus | Patent Foramen Ovale | Placenta Previa | Epidermolytic Ichthyosis, Annular | Waardenburg Syndrome Type 2 | Cherubism | Joubert Syndrome | Skin Carcinoma | Charcot-Marie-Tooth Disease Type 2T | Fahr Disease | Osteitis | Hypereosinophilic Syndrome | Aplastic Anemia | Atelosteogenesis Type 2 | Arthropathy | Gastroenteritis, Eosinophilic | Congenital Disorders Of Glycosylation Type II | Coma | Batten Disease | Waardenburg Syndrome Type 1 | Varicocele | Leukoplakia, Oral | Cousin Syndrome | Learning Disability | Inflammatory Linear Verrucous Epidermal Nevus | Melanoma | Amyotrophic Lateral Sclerosis-parkinsonism-dementia Complex | C3 Glomerulopathy | Disseminated Superficial Actinic Porokeratosis | Hereditary Multiple Exostoses | Proteus Syndrome | Lipid Storage Myopathy | Hypertension, Renal | Hereditary Sensory And Autonomic Neuropathy | Silver-Russell Syndrome | Craniopharyngioma | Delayed Sleep Phase Syndrome | Acute Motor Axonal Neuropathy | Palmoplantar Keratoderma | Presbyopia | Dermatitis | Clouston Hidrotic Ectodermal Dysplasia | Ligneous Conjunctivitis | Hypoglycemia | Sarcoma, Endometrial Stromal | IgA Nephropathy | McCune-Albright Syndrome | Charcot-Marie-Tooth Disease Axonal Type 2N | Benign Recurrent Intrahepatic Cholestasis 1 | Multiple Myeloma | 3-methylglutaconic Aciduria Type IV | Thymoma, Malignant | Hereditary Spherocytosis | Scleroderma | Renal Hypomagnesemia 3 | Leiomyosarcoma | Diffuse Intrinsic Pontine Glioma | Botulism | Cheilitis | Aicardi-Goutieres Syndrome | Alstrom Syndrome | Meningococcal Infections | Trichorhinophalangeal Syndrome | Neutropenia | Oculocutaneous Albinism Type 1 | Left Ventricular Noncompaction | Glutathione Synthetase Deficiency | Burn-McKeown Syndrome | Sleep Apnea, Central | Parapsoriasis | Alazami Syndrome | Brachydactyly | Joubert Syndrome 2 | REM Sleep Behavior Disorder | Bainbridge-Ropers Syndrome | Arts Syndrome | Hemochromatosis Type 2 | Esophageal Motility Disorders | Filariasis | Acute Leukemia | Cholecystitis | Polyneuropathy | Acute Generalized Exanthematous Pustulosis | Ganglioglioma | Desmosterolosis | Bardet-Biedl Syndrome | Tyrosinemia | Esophagitis, Eosinophilic | Dermatitis Herpetiformis | Fibrodysplasia Ossificans Progressiva | Alpha-1 Antitrypsin Deficiency | Charcot-Marie-Tooth Disease, Type 6 | Waardenburg Syndrome | Acute Coronary Syndrome | Wieacker-Wolff Syndrome | Argininosuccinic Aciduria | Phenylketonuria II | Agranulocytosis | Familial Advanced Sleep Phase Syndrome | Cushing Syndrome | Glutaric Aciduria Type 2 | Rhabdoid Tumor | Majeed Syndrome | Coffin-Siris Syndrome | Babesiosis | Trachoma | Hepatorenal Syndrome | Gerstmann-Straussler-Scheinker Syndrome | Episodic Ataxia Type 1 | Vascular Cognitive Impairment | Distal Myopathy | Zimmermann-Laband Syndrome | Urolithiasis | Multiple Sulfatase Deficiency | Choriocarcinoma | Anthrax | Progressive Myoclonic Epilepsy | Hamartoma | Seborrheic Dermatitis | Pachyonychia Congenita | Bone Giant Cell Tumor | Guttate Psoriasis | Primary Torsion Dystonia | Ataxia-hypogonadism-choroidal Dystrophy Syndrome | Hepatitis, Autoimmune | Schwartz-Jampel-Aberfeld Syndrome | Menkes Disease | Rolandic Epilepsy | Bietti Crystalline Dystrophy | Cystinuria | Fabry's Disease | Rift Valley Fever | Spondyloarthritis | Adenoma, Villous | Neurogenic Bladder | Tularemia | Blepharo-cheilo-odontic Syndrome | Spinocerebellar Ataxia Type 7 | Neurodegeneration With Brain Iron Accumulation | Leprosy | Blepharoconjunctivitis | Waardenburg Syndrome Type 4 | Eclampsia | Heroin Dependence | Lymphangioma | Waardenburg Syndrome Type 2A | Thyroid Hormone Resistance | GM2-gangliosidosis AB Variant | Erdheim-Chester Disease | Waardenburg Syndrome Type 2E | Macular Degeneration | Neurofibromatosis | Pancreatitis, Chronic | Hereditary Spastic Paraplegia | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Goiter | Priapism | Guanidinoacetate Methyltransferase Deficiency | Leber Hereditary Optic Neuropathy | Ollier Disease | Echinococcosis | Acne | Pulverulent Zonular Cataract | Macular Corneal Dystrophy Type 1 | Hidradenitis | Ulcerative Colitis | Glomerulonephritis | Metabolic Syndrome | Spinocerebellar Ataxia Type 8 | Creatine Deficiency Syndrome Due To AGAT Deficiency | Thrombosis | Familial Episodic Pain Syndrome | Fanconi Anemia | Wolfram Syndrome 2 | Kawasaki Disease | Chronic Idiopathic Myelofibrosis | Pseudohypoparathyroidism Type 1C | Oguchi Disease-2 | Chediak-Higashi Syndrome | Oculocutaneous Albinism | Hemangioblastoma | Globozoospermia | Progressive Familial Intrahepatic Cholestasis Type 3 | Cri-du-chat Syndrome | Spinocerebellar Ataxia Type 2 | Hypertension | Measles | Hoyeraal-Hreidarsson Syndrome | Sweet Syndrome | Angiodysplasia | Multicentric Carpotarsal Osteolysis Syndrome | Poikiloderma With Neutropenia | Japanese Encephalitis | Retinal Detachment | Reticular Dysgenesis | Moyamoya Disease | Coronary Heart Disease | Intracranial Hypertension | Keratosis, Actinic | Idiopathic Multicentric Castleman Disease | Intracerebral Hemorrhage | Fraser Syndrome | Leukoplakia | Coenzyme Q10 Deficiency | Usher Syndrome Type I | Angelman Syndrome | L-2-Hydroxyglutaric Aciduria | Wagner Disease | Neutrophilia | Primary Lateral Sclerosis | Combined Malonic And Methylmalonic Acidemia | Myoclonic Epilepsy With Ragged Red Fibers | Chondrodysplasia Punctata 2, X-linked Dominant | Rothmund-Thomson Syndrome | Diabetic Neuropathy | Keratitis | Sialoadenitis | Ehlers-Danlos Syndrome With Progressive Kyphoscoliosis, Myopathy, And Hearing Loss | Keratoconus | Diastrophic Dysplasia | Epidermolysis Bullosa Acquisita | Pelizaeus-Merzbacher Disease | Tay-Sachs Disease | Spinal And Bulbar Muscular Atrophy | Gastroschisis | Diarrhea | Hypoparathyroidism | Chudley-McCullough Syndrome | Cancer, Skin | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Noonan Syndrome-like Disorder With Loose Anagen Hair | Cryptosporidiosis | Genee-Wiedemann Syndrome | Hyperhomocysteinemia | Blau Syndrome | Pilomatrix Carcinoma | Anodontia | Atrial Septal Defect