Fetal Alcohol Syndrome

About the Disease
Alcohol-Related Birth Defects, also known as alcohol-related birth defect, is related to fetal alcohol syndrome and fetal alcohol spectrum disorder. An important gene associated with Alcohol-Related Birth Defects is ADH1B (Alcohol Dehydrogenase 1B (Class I), Beta Polypeptide), and among its related pathways/superpathways are Metabolism and Oxidation by cytochrome P450. The drugs Atomoxetine and Adrenergic Agents have been mentioned in the context of this disorder. Affiliated tissues include fetal brain, brain and bone, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Common Targets
Phosphodiesterase 1 (PDE1) (nonspecified subtype) | ALDH2 | ADH1B | HNF1B | ADH1C

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