Powered by AI technology, BDE-Bio combines massive literature, patent and comprehensive biological data to accurately screen and predict disease diagnosis and therapeutic targets / biomarkers. It can automatically generate target research reports with one click, making it an indispensable tool for pharmaceutical research and development.
BDE-Bio
TARGET PRECISE DISCOVERY
Product Introduction
BDE-Bio achieves precise screening and prediction of new targets by combining 24-hour continuous updates, massive literature texts, comprehensive biological databases, and large-scale multi-omics data, and can provide the basis and logic for target discovery.
1) Capture: 24-hour monitoring of Pubmed, 24 public databases (genecard, drugbank, pubchem, etc.), real-time inbound parsing.
2) Extraction: It can extract basic information about the target, protein structure, biological mechanism of the target, drug resistance of the target, disease correlation, etc.
3) Analysis: Summarize long content, generate reports with one click, recommend target points, etc.
Target Prediction
Predicting targets that can successfully enter the clinical trial stage and ensuring that lead compounds based on predicted targets can successfully break through the PCC stage within an estimated time frame.
Target-based Drug Prediction
Predicting the difficulty level of target-based drug development provides a basis for assessing the value of target exploration.
Disease-Related Target Prediction
Predicting key targets for specific diseases and provide a basis for drug development for rare diseases and difficult and complicated diseases.
Common Targets and Diseases
Targets
ABCB1 | ABCG2 | ACE2 | AHR | AKT1 | ALK | AR | ATM | BAX | BCL2 | BCL2L1 | BECN1 | BRAF | BRCA1 | CAMP | CASP3 | CASP9 | CCL5 | CCND1 | CD274 | CD4 | CD8A | CDH1 | CDKN1A | CDKN2A | CREB1 | CXCL8 | CXCR4 | DNMT1 | EGF | EGFR | EP300 | ERBB2 | EREG | ESR1 | EZH2 | FN1 | FOXO3 | HDAC9 | HGF | HMGB1 | HSP90AA1 | HSPA4 | HSPA5 | IDO1 | IFNA1 | IGF1 | IGF1R | IL17A | IL6 | INS | JUN | KRAS | MAPK1 | MAPK14 | MAPK3 | MAPK8 | MAPT | MCL1 | MDM2 | MET | MMP9 | MTOR | MYC | NFE2L2 | NLRP3 | NOTCH1 | PARP1 | PCNA | PDCD1 | PLK1 | PRKAA1 | PRKAA2 | PTEN | PTGS2 | PTK2 | RELA | SIRT1 | SLTM | SMAD4 | SOD1 | SQSTM1 | SRC | STAT1 | STAT3 | STAT5A | TAK1 | TERT | TLR4 | TNF | TP53 | TXN | VEGFA | YAP1
Diseases
Campomelic Dysplasia | Familial Hemiplegic Migraine | Oligoastrocytoma | Mucolipidosis Type IV | Jacobsen Syndrome | Nephrotic Syndrome | Auriculocondylar Syndrome | Facioscapulohumeral Muscular Dystrophy Type 1 | Familial Glucocorticoid Deficiency | Carotid Artery Disease | Neurofibroma, Plexiform | IMAGe Syndrome | Transthyretin-related Amyloidosis | Acute Kidney Injury | Granular Corneal Dystrophy Type 1 | Myocardial Infarction | Hypertension | Enterocolitis, Necrotizing | Lymphedema | Nijmegen Breakage Syndrome | Transcobalamin Deficiency | Leukemia | Paroxysmal Nocturnal Hemoglobinuria | Still Disease | Adrenomyeloneuropathy | Cerebrovascular Disorders | Lyme Disease | Sick Sinus Syndrome | Exfoliative Dermatitis | Stuve-Wiedemann Syndrome | Alstrom Syndrome | Persistent Fetal Circulation | Hypotension, Orthostatic | Myhre Syndrome | Osteochondrosis | Acquired Partial Lipodystrophy | Werner's Syndrome | Multiple Sclerosis, Relapsing-remitting | Dyggve-Melchior-Clausen Disease | Spondylometaphyseal Dysplasia | Cirrhosis | Maple Syrup Urine Disease | Keloid | Familial Thoracic Aortic Aneurysm | Angioedema, Acquired | Marshall-Smith Syndrome | Thrombophilia | Coronary Heart Disease | Stroke, Hemorrhagic | Uremia | Hydrolethalus Syndrome | Placenta Previa | Pancytopenia | Gingivitis | Hemophilia | Nevus | COACH Syndrome | Myoclonic Epilepsy With Ragged Red Fibers | Dermatomyositis | Retinal Dystrophy | Macular Corneal Dystrophy | Birk-Barel Syndrome | Desbuquois Syndrome | Japanese Encephalitis | Hypotrichosis | Hydrops Fetalis | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Incontinentia Pigmenti | Zellweger Syndrome | Agnathia-Otocephaly Complex | Graft-versus-host Disease | Schamberg Disease | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Galloway-Mowat Syndrome | Seizures | 17-beta-hydroxysteroid Dehydrogenase X Deficiency | Hashimoto Thyroiditis | Anencephaly | Pupil Disorders | Multiple Sclerosis, Primary Progressive | Schindler Disease | Kearns-Sayre Syndrome | Focal Segmental Glomerulosclerosis | Cryptococcal Meningitis | Chromosome 16p11.2 Deletion Syndrome | Myelitis, Transverse | Primrose Syndrome | Purpura, Thrombotic Thrombocytopenic | Autism | Conjunctivitis, Allergic | Chronic Inflammatory Demyelinating Polyneuropathy | Personality Disorders | Enlarged Vestibular Aqueduct | Corneal Ulcer | Hereditary Hemorrhagic Telangiectasia | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Mountain Sickness | FG Syndrome | Hypertelorism | Evans Syndrome | Lennox-Gastaut Syndrome | Trimethylaminuria | Persistent Truncus Arteriosus | Chromosome 5q Deletion Syndrome | Thanatophoric Dysplasia | Epidermolysis Bullosa Simplex With Mottled Pigmentation | Salla Disease | Apraxia | Gnathodiaphyseal Dysplasia | Meningitis | Hemorrhoids | Dyslipidemia | Vitreoretinopathy, Proliferative | Language Disorders | Chorea-acanthocytosis | Anuria | Schizotypal Personality Disorder | Tricho-hepato-enteric Syndrome | Central Retinal Artery Occlusion | Larsen Syndrome | Relapsing Polychondritis | Asplenia | Blastoma, Pleuropulmonary | IgA Nephropathy | Lupus Erythematosus | Mesothelioma, Malignant | Cysticercosis | Meleda Disease | Ectodermal Dysplasia | Jaundice, Obstructive | Olmsted Syndrome | Leigh Syndrome | Thyroiditis | Jalili Syndrome | Sitosterolemia | Hypohidrotic Ectodermal Dysplasia, X-linked | Sclerosteosis 2 | Synpolydactyly | Pure Autonomic Failure | T-cell Chronic Lymphocytic Leukemia | Angelman Syndrome | Pontocerebellar Hypoplasia Type 7 | Influenza | Melanoma, Malignant | Disseminated Superficial Actinic Porokeratosis | Spinocerebellar Ataxia Type 12 | Cranioectodermal Dysplasia | Optic Neuritis | Silicosis | Postaxial Polydactyly | Charcot-Marie-Tooth Disease | Familial Isolated Hyperparathyroidism | Neurofibrosarcoma | Neutropenia | Lymphoma, Primary Cutaneous Anaplastic Large Cell | Dystonia Musculorum Deformans | X-linked Acrogigantism | Insulinoma | Ataxia-hypogonadism-choroidal Dystrophy Syndrome | Renpenning Syndrome | Cutaneous Lupus Erythematosus | Renal Medullary Carcinoma | Pineoblastoma | Autoimmune Autonomic Ganglionopathy | Neuropathy | Hereditary Sensory And Autonomic Neuropathy | Leukemia-lymphoma, Adult T-cell | Precocious Puberty | Bladder Exstrophy | Malignant Fibrous Histiocytoma | Primary Pigmented Nodular Adrenocortical Disease | Corneal Dystrophies, Hereditary | Sporadic Hemiplegic Migraine | Alpha-1 Antitrypsin Deficiency | Spondylosis | Multifocal Motor Neuropathy | Dysplastic Nevus | Traboulsi Syndrome | GNE Myopathy | Retinal Diseases | GM2-gangliosidosis AB Variant | Ileitis | Retinal Coloboma | Tyrosinemia Type 2 | Usher Syndrome Type I | Large Granular Lymphocytic Leukemia | Emery-Dreifuss Muscular Dystrophy | Peritonitis | Corneal Edema | 3-methylglutaconic Aciduria | Protein S Deficiency | Androgenic Alopecia | Hypertensive Retinopathy | Acute Lung Injury | Donnai-Barrow Syndrome | Temtamy Preaxial Brachydactyly Syndrome | Distal Spinal Muscular Atrophy | Gyrate Atrophy Of The Choroid And Retina | Myelomeningocele | Batten Disease | Diabetes | Alzheimer Disease, Late Onset | Microcephaly, Seizures, And Developmental Delay | Prader-Willi Syndrome | Neuromyotonia | Primary Carnitine Deficiency | Costello Syndrome | Cheilitis | Eczema | Compartment Syndrome | Encephalitis | Vitamin B12 Deficiency | Roberts Syndrome | Rolandic Epilepsy | Nanophthalmos | Fragile X Syndrome | Congenital Mirror Movements | Familial Male-limited Precocious Puberty | Nicotine Dependence | Osteoglophonic Dysplasia | Ligneous Conjunctivitis | Congenital Adrenal Hyperplasia | Multiple Congenital Anomalies-hypotonia-seizures Syndrome 2 | Orotic Aciduria | Lipid Storage Myopathy | Allan-Herndon-Dudley Syndrome | Stargardt Disease | Sickle Cell Anemia | Hypervalinemia | Juvenile Xanthogranuloma | Hepatitis, Autoimmune | Acute Coronary Syndrome | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Diabetes Insipidus, Neurogenic | Hepatitis A | Polyneuropathy | Osteogenesis Imperfecta Type V | Congenital Diaphragmatic Hernia | Cholangiocarcinoma | Metabolic Diseases | Dysferlinopathy | Pycnodysostosis | Cataplexy | Myoclonic Atonic Epilepsy | Leukoencephalopathy, Progressive Multifocal | GLUT1 Deficiency Syndrome | Cluster Headache | Chronic Myeloid Leukemia | Stickler Syndrome | Cohen Syndrome | Mabry Syndrome | Bicuspid Aortic Valve | Budd-Chiari Syndrome | Cervicitis | Autosomal Recessive Bestrophinopathy | Noonan Syndrome-like Disorder With Loose Anagen Hair | Bone Marrow Necrosis | CHARGE Syndrome | Neurofibromatosis Type 2 | B-cell Chronic Lymphocytic Leukemia | Cerebellar Ataxia, Cayman Type | Takenouchi-Kosaki Syndrome | Myocarditis | Chondrodysplasia Punctata 2, X-linked Dominant | Shprintzen-Goldberg Syndrome | Avian Influenza | B-cell Prolymphocytic Leukemia | Intestinal Hypomagnesemia 1 | Generalized Epilepsy And Paroxysmal Dyskinesia | Immunoproliferative Disorders | Neonatal Progeroid Syndrome | Mast Cell Leukemia | Non-Langerhans Cell Histiocytosis | CDKL5 Deficiency Disorder | Scapuloperoneal Myopathy, X-linked Dominant | Osteosclerosis | Bone Giant Cell Tumor | Lymphangiomatosis | Phenylketonuria | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Spinocerebellar Ataxia Type 1 | Melanocytic Nevus | Light Chain Amyloidosis | Impetigo | Fukuyama Congenital Muscular Dystrophy | Otopalatodigital Syndrome Type 2 | Rickets | Moyamoya Disease | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Asphyxia Neonatorum | Obsessive-compulsive Disorder | Lymphoma Lymphoblastic | Krabbe Disease | Crisponi Syndrome | Diffuse Intrinsic Pontine Glioma | Lysosomal Acid Lipase Deficiency | Blomstrand Osteochondrodysplasia | Basal Ganglia Cerebrovascular Disease | Hereditary Coproporphyria | Asthma, Nocturnal | Megaloblastic Anemia | Achromatopsia | Glaucoma | Reticular Dysgenesis | Pitt-Hopkins Syndrome | Lassa Fever | Saethre-Chotzen Syndrome | Chromosome 17q21.31 Deletion Syndrome | Meningeal Melanocytoma | Pulmonary Alveolar Proteinosis | Stomatitis | Bietti Crystalline Dystrophy | PASLI Disease | Periodic Limb Movement Disorder | Gastritis, Atrophic | Benign Hereditary Chorea | Whipple's Disease | Open-angle Glaucoma | Retinal Dystrophy, Early-onset Severe | Cardiospondylocarpofacial Syndrome | Coffin-Lowry Syndrome | Pemphigoid | Cerebellofaciodental Syndrome | Hyperphenylalaninemia | Hypohidrotic Ectodermal Dysplasia | Prolidase Deficiency | Hypopituitarism | Androgen Insensitivity | Liebenberg Syndrome | Epithelioid Hemangioma | Lymphoma, AIDS-related | Vertebrobasilar Insufficiency | Fuchs Dystrophy | Pyruvate Dehydrogenase Deficiency | Renal Dysplasia | Microtia | Facioscapulohumeral Muscular Dystrophy Type 2 | Choroiditis | Congenital Generalized Lipodystrophy | Nephronophthisis | Acne Vulgaris | Globozoospermia | Cartilage Disorders | Citrullinemia | Gangliosidosis | Adenomyosis | Hypokalemia | Keratosis, Seborrheic | Nicolaides-Baraitser Syndrome | Richter's Syndrome | Malignant Peripheral Nerve Sheath Tumor | Tyrosinemia | Down Syndrome | Congenital Hereditary Endothelial Dystrophy Type II | Eccrine Porocarcinoma | HELLP Syndrome | Inflammatory Myopathy | Rhabdomyosarcoma, Embryonal | Pontocerebellar Hypoplasia Type 2 | GATA2 Deficiency | Niemann-Pick Disease | Autonomic Neuropathy | Myeloid Leukemia | Corneal Dystrophy | Thromboembolism | Dent Disease | Gardner Syndrome | Axenfeld-Rieger Syndrome | Skin Papilloma | Heroin Dependence | Tremor | Erythrokeratodermia Variabilis | Heimler Syndrome | Anxiety Disorders | Peutz-Jeghers Syndrome | Retinal Telangiectasia | Alkaptonuria | Ornithine Transcarbamylase Deficiency | Dengue Hemorrhagic Fever | Hepatitis D | Vitiligo | Cervical Dystonia | Benign Familial Infantile Seizures | Zimmermann-Laband Syndrome | Juvenile Myelomonocytic Leukemia | Chorea | Wiedemann-Steiner Syndrome | Nephrosclerosis | Proctitis | Hidradenitis | Sick Sinus Syndrome 1 | Angiodysplasia | Acute Motor Axonal Neuropathy | Keratopathy | Cone Dystrophy | Frontotemporal Dementia | Adenomatoid Tumor | Osteogenesis Imperfecta Type III | Anovulation | Meconium Ileus