Bladder Exstrophy

About the Disease
Bladder Exstrophy, also known as exstrophy of the bladder, is related to bladder exstrophy-epispadias-cloacal exstrophy complex and cloacal exstrophy. An important gene associated with Bladder Exstrophy is ISL1 (ISL LIM Homeobox 1), and among its related pathways/superpathways are Transcription Androgen Receptor nuclear signaling and Embryonic and Induced Pluripotent Stem Cells and Lineage-specific Markers. The drugs Anesthetics, General and Anesthetics have been mentioned in the context of this disorder. Affiliated tissues include prostate, smooth muscle and colon, and related phenotypes are umbilical hernia and vesicoureteral reflux

Common Targets
CCDC15 | LOC105377844 | LOC105377845 | ISL1-DT | SMOC2 | DHRS4L1 | LIAS | CELSR1 | MECOM | RPL9 | MEGF6 | PREX2 | MROH9 | LOC105369862 | SYT1 | CREB5 | MIR1252 | NCKAP5 | ISL1

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