Sarcoma

About the Disease
Malignant Mesenchymoma, also known as malignant mesenchymal tumor, is related to gallbladder sarcoma and leiomyosarcoma. An important gene associated with Malignant Mesenchymoma is SERPINA3 (Serpin Family A Member 3), and among its related pathways/superpathways are Mesenchymal Stem Cells and Lineage-specific Markers and Myogenesis. The drugs Ritonavir and Lopinavir have been mentioned in the context of this disorder. Affiliated tissues include t cells, uterus and bone, and related phenotype is muscle.

Common Targets
TGFBR2 | EWSR1 | CD19 | TLR7 | Fibroblast Growth Factor Receptor (FGFR) (nonspecified subtype) | TNFRSF10B | G238 | IL2RB | CHEK2 | APC | YES1 | BICRA | MAGEA3 | G6714 | NTRK2 | HCK | CTNNB1 | MLH1 | NF2 | KDR | PARP3 | DNA Methyltransferase (DNMT) (nonspecified subtype) | CD248 | FGR | MDM4 | G472 | Protein farnesyltransferase | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | AURKA | CSF3 | TLR8 | OGDH | G1956 | ABL1 | INPP4B | G3845 | FAP | FOXO1 | IGF2R | PTPRD | PDIA2 | gamma-Secretase | FGF3 | Serine/Threonine Kinase (nonspecified subtype) | Pyruvate Dehydrogenase Complex | ASXL1 | G2335 | TMEM132A | CD99 | G3569 | CSK | FZD10 | G3620 | G7015 | SMO | G5594 | FAT4 | CTAG1A | G59272 | HDAC2 | BTK | FGF4 | Heat shock protein 90 (nonspecified subtype) | DNMT3A | HOXB13 | HRAS | KMT2C | ATRX | G595 | ELANE | Folate Receptor (nonspecified subtype) | FKBP1A | WDR37 | USP19 | Hedgehog Protein (nonspecified subtype) | NPM1 | G3725 | CDK6 | Ephrin Receptor (nonspecified subtype) | CHEK1 | NRAS | PPARA | Protein Kinase B (PKB/Akt) (nonspecified subtype) | LCK | AXL | Phosphatidylinositol 3-kinase (PI3K) (nonspecified subtype) | NF-kappaB (NFkB) | LAG3 | G7099 | GATA6 | EED | ALDH2 | LOC102724428 | Protein kinase C (nonspecified subtype) | BRD2 | CSF1R | mTOR complex 1 | G5133 | CSF3R | G7295 | EMSY | KEAP1 | CD3 Complex (T Cell Receptor Complex) | TNFSF11 | FRMD4A | IDH1 | TOP1 | G4851 | CDK4 | SUZ12 | KIT | NOTCH4 | G29126 | ARG1 | DDR2 | GID4 | RNF213 | BCR | XIAP | KAT6A | BRD4 | GADD45A | PIK3CD | FACT complex | DNA Topoisomerase II (nonspecified subtype) | G673 | FLI1 | CDK9 | HSD11B1 | XPO1 | GATA2 | FOXA1 | CD22 | NTRK3 | RICTOR | G142 | LILRB2 | TET2 | G1029 | STK11 | PDGFRB | Reverse transcriptase (Telomerase) | PTCH1 | G4170 | HDAC1 | POT1 | G4609 | NTRK1 | FGF10 | GSK3B | DICER1 | G9429 | G2475 | mTOR complex 2 | HOPX | G3480 | EPHB6 | MSMB | HDAC4 | FLT4 | FGF19 | IDH2 | G2099 | CKS1B | MPL | FRK | KAT6B | RAD51 | KNSTRN | Heat shock protein 70 (nonspecified subtype) | FLT1 | KHDC1 | CCNE1 | RAF1 | SIK2 | BLK | G7157 | PIM1 | DDR1 | RB1 | DGCR2 | BRD3 | ENTPD1 | TH | G4193 | FASLG | SRSF2 | TNFRSF4 | CTAG1B | NOX3 | Notch receptor (nonspecified subtype) | MAS1 | LYN | Angiotensin receptor (AT) (nonspecified subtype) | Histamine Receptor (HR) (nonspecified subtype) | SYNE1 | SIK1 | LRP2 | G1786 | Tubulin | RUNX1 | NF1 | G5743 | NT5E | SMARCB1 | LRP1B | PARP2 | G4233 | PRRC2C | FRS2 | COL2A1 | CTLA4 | TRPA1 | CCR5 | NADPH Oxidase Complex | PIK3CA | G2064 | KMT2D | FYN | DAXX | PTPN11 | FAM151A | PDGFRA | ZWINT | FLT3 | RET | ARID1A | MGMT | CD276 | Proteasome Complex | TOP2A | Histone deacetylase (nonspecified subtype) | PPT1 | NADPH Oxidase (nonspecified subtype) | MYLIP | CD226 | G5243

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