Myositis

About the Disease
Inclusion Body Myositis, also known as sporadic inclusion body myositis, is related to myositis and myopathy, and has symptoms including back pain, muscle cramp and muscle rigidity. An important gene associated with Inclusion Body Myositis is GNE (Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase), and among its related pathways/superpathways are Neuroscience and miRNAs involvement in the immune response in sepsis. The drugs Mycophenolic acid and Prednisone have been mentioned in the context of this disorder. Affiliated tissues include skeletal muscle, bone and eye, and related phenotypes are skeletal muscle atrophy and autoimmunity

Common Targets
Interferon-alpha (IFN-alpha) (nonspecified subtype) | HLA-A | DNA Topoisomerase II (nonspecified subtype) | PSMB9 | IFI44L | TNFSF13B | JAK2 | LILRA4 | JAK1 | JAK3 | PON1 | Immunoproteasome | IL6R | KLRG1 | HLA-DRB1 | PSMB8 | HDAC6 | HLA-B | CD226 | TOP1 | CX3CL1

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