Cutaneous T-cell Lymphoma

About the Disease
Primary Cutaneous T-Cell Non-Hodgkin Lymphoma, also known as cutaneous t-cell lymphoma, is related to primary cutaneous gamma-delta t-cell lymphoma and parapsoriasis. An important gene associated with Primary Cutaneous T-Cell Non-Hodgkin Lymphoma is TNFRSF8 (TNF Receptor Superfamily Member 8), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Levoleucovorin and Methotrexate have been mentioned in the context of this disorder. Affiliated tissues include t cells, skin and bone marrow, and related phenotypes are no effect and no effect

Common Targets
TRBC1 | Histone deacetylase (nonspecified subtype) | KIR3DL2 | Proteasome Complex | ITGAM | PASK | G5243 | LPL | TLR7 | PIK3CG | G7124 | Tumor-Associated Glycoprotein 72 (TAG-72) | IL6ST | JAK3 | JAK1 | PSMB5 | HDAC10 | G596 | IL-15 receptor | G3845 | TLR8 | CD6 | TNFRSF1B | KCNA3 | Geranylgeranyl transferase type-1 | JAK2 | G5594 | Interferon-gamma Receptor | G6774 | HDAC6 | DNMT3A | HDAC2 | HIF1A | MIR155 | CARD11 | NRAS | CCR4 | SOCS5 | MAP3K5 | IL2RA | G3569 | GLI3 | FKBP1A | PAK5 | CD79A | TRAF6 | G598 | Phosphatidylinositol 3-kinase (PI3K) (nonspecified subtype) | Protein kinase C (nonspecified subtype) | G5133 | CD3 Complex (T Cell Receptor Complex) | HDAC11 | NF-kappaB (NFkB) | G29126 | IL-2 receptor | FLNA | ABCA1 | IL15 | HDAC3 | SIRPA | DNA Topoisomerase II (nonspecified subtype) | PIK3CD | STAT5 (nonspecified subtype) | RC3H1 | HDAC1 | SATB1 | SYK | G3605 | FCGR3A | G920 | Interferon (nonspecified subtype) | ACHE | Immunoglobulin E (IgE) | PPARG | PNP | PLCG1 | BCOR | NCR3 | IL17F | IL31 | G2475 | NLRP2 | SPI1 | RARB | G3630 | RELB | G836 | HK2 | Mitogen-Activated Protein Kinase (nonspecified subtype) | RB1 | POLA1 | PIM1 | Janus Kinase (nonspecified subtype) | G7157 | TNFRSF8 | NAMPT | Retinoid RXR receptor (nonspecified subtype) | CD37 | FCER1A | FAS | TLR9 | CD47 | Tubulin | CD28 | RARG | IL9R | Mitogen-activated protein kinase (JNK) (nonspecified subtype) | LRRC43 | MGMT | DHFR | VHL | RHOA | IFNAR2 | TOP2A

Note: If you'd like to get a target analysis report for Cutaneous T-cell Lymphoma, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Cutaneous T-cell Lymphoma at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Postpoliomyelitis Syndrome | Diabetes Type 2 | Nicolaides-Baraitser Syndrome | Galloway-Mowat Syndrome | Pulmonary Vein Stenosis | Ligneous Conjunctivitis | Osteogenesis Imperfecta | Congenital Hereditary Endothelial Dystrophy Type II | Blue Nevus | Familial Thoracic Aortic Aneurysm | Cerebral Cavernous Malformations | Keratoacanthoma | Pseudohypoparathyroidism Type 1B | Colitis, Microscopic | Hepatitis A | Myoclonic Epilepsy With Ragged Red Fibers | Mucormycosis | Glycogen Storage Disease Type 9 | Limb Girdle Muscular Dystrophy | Wagner Disease | Agnathia-Otocephaly Complex | Microcephaly | Bronchitis | Cysticercosis | Multiple System Atrophy | HUPRA Syndrome | Astrocytoma | Dystonia-parkinsonism, X-linked | Pompe Disease | Mitochondrial Encephalomyopathy | Osteosarcoma | Neurodermatitis | Joubert Syndrome | Thymoma, Malignant | 6-pyruvoyl-tetrahydropterin Synthase Deficiency | Chondrosarcoma | Rhabdoid Tumor | Syndactyly | Frontometaphyseal Dysplasia | Spasticity | Lattice Corneal Dystrophy Type 1 | Argininosuccinic Aciduria | Trichuriasis | Adenoma, Pituitary | Budd-Chiari Syndrome | Smith-Kingsmore Syndrome | Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy | Waldenstrom Macroglobulinemia | Achondrogenesis | Encephalopathy, Glycine | Jawad Syndrome | Sarcoma, Ewing | Guttate Psoriasis | Tyrosinemia Type 2 | Hereditary Pyropoikilocytosis | NGLY1 Deficiency | Hepatorenal Syndrome | Cystinosis | Persistent Truncus Arteriosus | Varicocele | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 1 | Crouzon Syndrome With Acanthosis Nigricans | Ophthalmia, Sympathetic | Atelosteogenesis Type 1 | Sarcoma | Follicular Dendritic Cell Sarcoma | Sarcoidosis | Nephropathy | Epidermolysis Bullosa Simplex | Schindler Disease | Thrombotic Microangiopathy | Stickler Syndrome | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Myotonic Disorders | Familial Pheochromocytoma-paraganglioma | Exostoses | Hyperinsulinemia | Congenital Bile Acid Synthesis Defect | Hemorrhage | Agoraphobia | Panniculitis | Burn-McKeown Syndrome | Split Hand-foot Malformation | Pulverulent Zonular Cataract | Hereditary Elliptocytosis | Angioedema, Acquired | Liver Failure, Acute Infantile | Spinal Muscular Atrophy Type 3 | Borjeson-Forssman-Lehmann Syndrome | Macrophage Activation Syndrome | Primary Familial Brain Calcification | Pulmonary Alveolar Microlithiasis | Hypercalciuria | Spinocerebellar Ataxia Type 38 | Prolactinoma | Autosomal Recessive Congenital Ichthyosis | Hereditary Coproporphyria | Lymphoma, B-cell | Mast Cell Leukemia | Carcinoma, Small Cell | Inborn Errors Of Metabolism | Emery-Dreifuss Muscular Dystrophy | Macrodactyly | Lymphangiomatosis | Giant Cell Glioblastoma | Chronic Leukemia | Teratozoospermia | Chronic Myeloid Leukemia | Aphasia | Alstrom Syndrome | Hernia, Inguinal | Alpha-thalassemia Myelodysplasia Syndrome | Gerodermia Osteodysplastica | Hypertension, Renal | Sweet Syndrome | Encephalitis, Tick-borne | Renal Failure | Monilethrix | Multifocal Motor Neuropathy | Dermatofibrosarcoma | Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form | Angiosarcoma | Multisystemic Smooth Muscle Dysfunction Syndrome | Glioblastoma Multiforme | Situs Inversus | Persistent Hyperplastic Primary Vitreous | Polycythemia Vera | Congenital Muscular Dystrophy | Cohen Syndrome | Urolithiasis | Congenital Stationary Night Blindness | Double Outlet Right Ventricle | Cancer, Prostate | Spinal Muscular Atrophy Type 2 | Gastroschisis | Myosin Storage Myopathy | Neurogenic Bladder | 17-beta-hydroxysteroid Dehydrogenase X Deficiency | Otitis Externa | Orotic Aciduria | Hemangioendothelioma | Neurodevelopmental Disorders | Duane Retraction Syndrome | Pelizaeus-Merzbacher Disease | Poikiloderma With Neutropenia | Inflammatory Myopathy | Hepatopulmonary Syndrome | Multiple Sclerosis, Primary Progressive | Stevens-Johnson Syndrome | Rett Syndrome | Diabetes Type 1 | Cardiac Arrest | Leukodystrophies | Chronic Neutrophilic Leukemia | Pierpont Syndrome | Tenosynovial Giant Cell Tumor | Blau Syndrome | Dubin-Johnson Syndrome | Combined Deficiency Of Factor V And Factor VIII | Tumoral Calcinosis | Craniosynostosis | Joubert Syndrome 2 | Multiple Sulfatase Deficiency | Delayed Sleep Phase Syndrome | Thrombophlebitis | Ganglioneuroma | Hydrolethalus Syndrome | Androgenic Alopecia | Conjunctivitis | Azoospermia | Hypotrichosis | Corneal Dystrophies, Hereditary | Focal Dermal Hypoplasia | Iron Metabolism Disorders | Goiter | Cardiomyopathy, Hypertrophic | Myelitis, Transverse | Wolff-Parkinson-White Syndrome | Heroin Dependence | Cholestasis, Intrahepatic | Dwarfism | Galactosialidosis | Norrie Disease | ACTH-independent Macronodular Adrenal Hyperplasia | Schizoaffective Disorder | Granular Corneal Dystrophy | Lattice Corneal Dystrophy | Lesch-Nyhan Syndrome | Autism | Fucosidosis | Antithrombin III Deficiency | Nasodigitoacoustic Syndrome | Gnathodiaphyseal Dysplasia | Chronic Idiopathic Myelofibrosis | Diffuse Mesangial Sclerosis | Trichorhinophalangeal Syndrome | Low Phospholipid Associated Cholelithiasis | Focal Cortical Dysplasia Type 2 | Gigantism | Pure Red Cell Aplasia | Cataplexy | Stargardt Disease | Still Disease | Pathological Gambling | Uveitis | Esophagitis, Eosinophilic | Hypoproteinemia, Hypercatabolic | Retinal Dystrophy, Early-onset Severe | Disseminated Superficial Actinic Porokeratosis | Peutz-Jeghers Syndrome | Biotinidase Deficiency | Cirrhosis | Schistosomiasis | Malaria | Polymicrogyria | Stiff-man Syndrome | Colitis, Collagenous | Nicotine Addiction | AIDS | Cardiomyopathy, Peripartum | Kashin-Beck Disease | Fibromyalgia | Familial Hypobetalipoproteinemia | Leishmaniasis, Visceral | Congenital Heart Defects | Light Chain Amyloidosis | Anodontia | Dyggve-Melchior-Clausen Disease | Vestibular Disease | Porphyria Cutanea Tarda | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Panic Disorder | Van Der Knaap Disease | Carbamoyl Phosphate Synthetase I Deficiency | B-cell Prolymphocytic Leukemia | Creatine Deficiency Syndrome Due To AGAT Deficiency | Gangliosidosis, GM1 | Succinic Semialdehyde Dehydrogenase Deficiency | Ectrodactyly | Spinocerebellar Ataxia Type 1 | Osteopathia Striata With Cranial Sclerosis | Neurodegeneration With Brain Iron Accumulation | Mucolipidosis | Chylomicron Retention Disease | X-linked Myotubular Myopathy | Metachromatic Leukodystrophy | Multiple Hamartoma Syndrome | Premenstrual Syndrome | Diffuse Intrinsic Pontine Glioma | Osteochondroma | Huntington's Disease | Intestinal Hypomagnesemia 1 | Hyperprolactinemia | Acute Motor Axonal Neuropathy | Microcephaly, Seizures, And Developmental Delay | Vascular Cognitive Impairment | Hemolytic Uremic Syndrome | Autism Spectrum Disorders | Atherosclerosis | Kernicterus | Pterygium | Small Lymphocytic Lymphoma | Distal Myopathy | Muscular Dystrophy | Erythema Nodosum | Behavioral Variant Of Frontotemporal Dementia | Pontocerebellar Hypoplasia Type 2 | Antley-Bixler Syndrome | Cannabis Abuse | Osteochondrosis | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Alveolar Capillary Dysplasia | Anuria | Glaucoma, Congenital | Large Granular Lymphocytic Leukemia | Impulse Control Disorder | Acrodysostosis | Psoriasis | FG Syndrome | Aldosteronism | Encephalopathy, Ethylmalonic | Withdrawal Syndrome | Von Willebrand Disease | Neonatal Progeroid Syndrome | Chorea-acanthocytosis | Spinocerebellar Ataxia Type 28 | Myositis, Focal | Premature Ejaculation | Hereditary Multiple Exostoses | Acne Vulgaris | Motion Sickness | Nephrotic Syndrome Type 1 | Non-epidermolytic Palmoplantar Keratoderma | Oculopharyngeal Muscular Dystrophy | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Tetanus | Chronic Periodontitis | Borderline Personality Disorder | Lentigo | Histoplasmosis | Shprintzen-Goldberg Syndrome | Mabry Syndrome | Arthropathy | Melnick-Needles Syndrome | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Ependymoma | Progressive Myoclonic Epilepsy | Pleural Tuberculosis | Vitamin D Deficiency | Wolman Disease | Hypobetalipoproteinemias | Lamellar Ichthyosis | Hepatitis, Autoimmune | Fraser Syndrome | Arthritis, Reactive | Meckel-Gruber Syndrome | Pulmonary Veno-occlusive Disease | Hyperuricemic Nephropathy, Familial Juvenile | Benign Familial Infantile Seizures | Myopathy | Gastric Atrophy | Language Disorders | Geleophysic Dysplasia | Panuveitis | Mixed Connective Tissue Disease | HELLP Syndrome | Pneumoconiosis | Gliosarcoma | Fibrosis | Genee-Wiedemann Syndrome | Congenital Adrenal Hyperplasia | Spinocerebellar Ataxia Type 13 | Hypermethioninemia | Analgesia | Long QT Syndrome Type 2 | Hyperkalemic Periodic Paralysis | Hemophagocytic Lymphohistiocytosis | Renal Hypouricemia | Acute Generalized Exanthematous Pustulosis | Hypersensitivity Pneumonitis | Non-Langerhans Cell Histiocytosis | Meniere's Disease | Haim-Munk Syndrome | Hereditary Spastic Paraplegia | Epilepsy Of Infancy With Migrating Focal Seizures | McCune-Albright Syndrome | Persistent Fetal Circulation | Cyclic Vomiting Syndrome | Kabuki Syndrome 2 | Peripheral T-cell Lymphoma | Cholestasis | Meconium Ileus | Skin Papilloma | Papilloma | Congenital Lipoid Adrenal Hyperplasia | Esophageal Adenocarcinoma | Aldosterone Deficiency | Absence Epilepsy | Carcinoma In Situ | Sarcosinemia | Hepatic Adenomatosis | Learning Disability | Cartilage Disorders | Rhabdomyosarcoma, Alveolar | Cutaneous Angiosarcoma | Vitamin K Deficiency | Dysequilibrium Syndrome | CEDNIK Syndrome | Schaaf-Yang Syndrome | Optic Atrophy 2 | Craniolenticulosutural Dysplasia | Stuttering | Aldosterone Synthase Deficiency | Primary Ovarian Insufficiency | Coloboma | Crohn's Disease | CHOPS Syndrome | Central Core Disease | Sleep Apnea, Central | Silicosis | Microphthalmia | CREST Syndrome | Adrenal Insufficiency | Tyrosinemia Type 1 | Acromesomelic Dysplasia | Blepharoconjunctivitis | Axenfeld-Rieger Syndrome | Obsessive-compulsive Disorder | Parvovirus B19 Infection | Measles | Polydactyly | Leiomyosarcoma | Cryptococcal Meningitis | Dyskeratosis Congenita | Combined Malonic And Methylmalonic Acidemia | C3 Glomerulopathy | Binge Eating Disorder | Histiocytic Sarcoma | B-cell Chronic Lymphocytic Leukemia | Pseudohypoparathyroidism Type 1A