Cutaneous T-cell Lymphoma

About the Disease
Primary Cutaneous T-Cell Non-Hodgkin Lymphoma, also known as cutaneous t-cell lymphoma, is related to primary cutaneous gamma-delta t-cell lymphoma and parapsoriasis. An important gene associated with Primary Cutaneous T-Cell Non-Hodgkin Lymphoma is TNFRSF8 (TNF Receptor Superfamily Member 8), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Levoleucovorin and Methotrexate have been mentioned in the context of this disorder. Affiliated tissues include t cells, skin and bone marrow, and related phenotypes are no effect and no effect

Common Targets
TRBC1 | Histone deacetylase (nonspecified subtype) | KIR3DL2 | Proteasome Complex | ITGAM | PASK | G5243 | LPL | TLR7 | PIK3CG | G7124 | Tumor-Associated Glycoprotein 72 (TAG-72) | IL6ST | JAK3 | JAK1 | PSMB5 | HDAC10 | G596 | IL-15 receptor | G3845 | TLR8 | CD6 | TNFRSF1B | KCNA3 | Geranylgeranyl transferase type-1 | JAK2 | G5594 | Interferon-gamma Receptor | G6774 | HDAC6 | DNMT3A | HDAC2 | HIF1A | MIR155 | CARD11 | NRAS | CCR4 | SOCS5 | MAP3K5 | IL2RA | G3569 | GLI3 | FKBP1A | PAK5 | CD79A | TRAF6 | G598 | Phosphatidylinositol 3-kinase (PI3K) (nonspecified subtype) | Protein kinase C (nonspecified subtype) | G5133 | CD3 Complex (T Cell Receptor Complex) | HDAC11 | NF-kappaB (NFkB) | G29126 | IL-2 receptor | FLNA | ABCA1 | IL15 | HDAC3 | SIRPA | DNA Topoisomerase II (nonspecified subtype) | PIK3CD | STAT5 (nonspecified subtype) | RC3H1 | HDAC1 | SATB1 | SYK | G3605 | FCGR3A | G920 | Interferon (nonspecified subtype) | ACHE | Immunoglobulin E (IgE) | PPARG | PNP | PLCG1 | BCOR | NCR3 | IL17F | IL31 | G2475 | NLRP2 | SPI1 | RARB | G3630 | RELB | G836 | HK2 | Mitogen-Activated Protein Kinase (nonspecified subtype) | RB1 | POLA1 | PIM1 | Janus Kinase (nonspecified subtype) | G7157 | TNFRSF8 | NAMPT | Retinoid RXR receptor (nonspecified subtype) | CD37 | FCER1A | FAS | TLR9 | CD47 | Tubulin | CD28 | RARG | IL9R | Mitogen-activated protein kinase (JNK) (nonspecified subtype) | LRRC43 | MGMT | DHFR | VHL | RHOA | IFNAR2 | TOP2A

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