Coloboma

About the Disease
Coloboma of Macula, also known as coloboma, is related to papillorenal syndrome and coloboma of optic nerve. An important gene associated with Coloboma of Macula is FZD5 (Frizzled Class Receptor 5), and among its related pathways/superpathways are Ectoderm differentiation and Mesodermal commitment pathway. Affiliated tissues include eye, retina and heart, and related phenotypes are macular coloboma and nervous system

Common Targets
RARA | PUF60 | BMP4 | TWF1 | MAB21L2 | PAX2 | ABI3BP | BMP7 | SALL2 | BMP3 | MIR204 | ABCB6 | LARP4B | STAB2 | PACS1 | PTCH1 | RBP4 | CHD7 | TANC2 | KLHL22 | TFAP2A | LCP1 | RARB | FZD5 | CDON | ACTG1 | CYP1B1 | PPP1R15B | SOX11 | ALDH1A3 | G10413 | KAT2B | CLDN19

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