Powered by AI technology, BDE-Bio combines massive literature, patent and comprehensive biological data to accurately screen and predict disease diagnosis and therapeutic targets / biomarkers. It can automatically generate target research reports with one click, making it an indispensable tool for pharmaceutical research and development.
BDE-Bio
TARGET PRECISE DISCOVERY
Product Introduction
BDE-Bio achieves precise screening and prediction of new targets by combining 24-hour continuous updates, massive literature texts, comprehensive biological databases, and large-scale multi-omics data, and can provide the basis and logic for target discovery.
1) Capture: 24-hour monitoring of Pubmed, 24 public databases (genecard, drugbank, pubchem, etc.), real-time inbound parsing.
2) Extraction: It can extract basic information about the target, protein structure, biological mechanism of the target, drug resistance of the target, disease correlation, etc.
3) Analysis: Summarize long content, generate reports with one click, recommend target points, etc.
Target Prediction
Predicting targets that can successfully enter the clinical trial stage and ensuring that lead compounds based on predicted targets can successfully break through the PCC stage within an estimated time frame.
Target-based Drug Prediction
Predicting the difficulty level of target-based drug development provides a basis for assessing the value of target exploration.
Disease-Related Target Prediction
Predicting key targets for specific diseases and provide a basis for drug development for rare diseases and difficult and complicated diseases.
Common Targets and Diseases
Targets
ABCB1 | ABCG2 | ACE2 | AHR | AKT1 | ALK | AR | ATM | BAX | BCL2 | BCL2L1 | BECN1 | BRAF | BRCA1 | CAMP | CASP3 | CASP9 | CCL5 | CCND1 | CD274 | CD4 | CD8A | CDH1 | CDKN1A | CDKN2A | CREB1 | CXCL8 | CXCR4 | DNMT1 | EGF | EGFR | EP300 | ERBB2 | EREG | ESR1 | EZH2 | FN1 | FOXO3 | HDAC9 | HGF | HMGB1 | HSP90AA1 | HSPA4 | HSPA5 | IDO1 | IFNA1 | IGF1 | IGF1R | IL17A | IL6 | INS | JUN | KRAS | MAPK1 | MAPK14 | MAPK3 | MAPK8 | MAPT | MCL1 | MDM2 | MET | MMP9 | MTOR | MYC | NFE2L2 | NLRP3 | NOTCH1 | PARP1 | PCNA | PDCD1 | PLK1 | PRKAA1 | PRKAA2 | PTEN | PTGS2 | PTK2 | RELA | SIRT1 | SLTM | SMAD4 | SOD1 | SQSTM1 | SRC | STAT1 | STAT3 | STAT5A | TAK1 | TERT | TLR4 | TNF | TP53 | TXN | VEGFA | YAP1
Diseases
Congenital Adrenal Hyperplasia 1 | Vitamin D Deficiency | Basan Syndrome | Glucagonoma | Leri Pleonosteosis | Prolactinoma | Lichen Planus | 3-hydroxy-3-methylglutaric Aciduria | Stroke, Ischemic | Early Infantile Epileptic Encephalopathy | Nephrotic Syndrome | Milk Allergy | Conn Syndrome | Hypogammaglobulinemia | Ghosal Syndrome | Parkinsonism | Obesity, Morbid | Ovarian Sex Cord-stromal Tumor | Meningococcal Meningitis | Sialoadenitis | Communication Disorders | Spondylosis | Pemphigoid | Fucosidosis | Keratosis, Seborrheic | Methemoglobinemia | Waardenburg Syndrome Type 2E | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Acne Vulgaris | Pancytopenia | Aspergillosis | Cutis Laxa | Dystrophy, Cone-rod | Nance-Horan Syndrome | Hepatic Steatosis | Lymphoma Lymphoblastic | Robinow Syndrome | Schwannoma | Stuve-Wiedemann Syndrome | Filariasis | Cavitary Optic Disc Anomalies | Lipoma | Micropenis | Hyperostosis | Spinocerebellar Ataxia Type 8 | Congenital Adrenal Hyperplasia | Thyrotoxic Periodic Paralysis | Premature Ejaculation | Hypertension | Systemic Mastocytosis | Saul-Wilson Syndrome | Brooke-Spiegler Syndrome | Usher Syndrome Type IIC | Feingold Syndrome | Hereditary Sensory Neuropathy Type 1 | Fanconi Syndrome | Growth Hormone Excess | Chronic Neutrophilic Leukemia | Diffuse Palmoplantar Keratoderma | Myopathy | Primary Hyperoxaluria Type 1 | X-linked Creatine Transporter Deficiency | Blepharitis | Thrombosis | Familial Episodic Pain Syndrome | Basal Ganglia Cerebrovascular Disease | Turner's Syndrome | Branchiootorenal Syndrome | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Plasmacytoma | Twin-to-twin Transfusion Syndrome | Systemic Lupus Erythematosus | Chronic Lymphocytic Leukemia | Craniopharyngioma | Neurofibromatosis Type 2 | Chondrodysplasia Punctata | Juvenile Polyposis | Carpal Tunnel Syndrome | Transient Bullous Dermolysis Of The Newborn | Moyamoya Disease | Sandhoff Disease | Gastritis | Veno-occlusive Disease | Esthesioneuroblastoma | Huntington's Disease | Ataxia-hypogonadism-choroidal Dystrophy Syndrome | Episodic Ataxia Type 2 | Platyspondylic Lethal Skeletal Dysplasia, Torrance Type | Chromosome 8q21.11 Deletion Syndrome | Idiopathic Multicentric Castleman Disease | Leukemia-lymphoma, Adult T-cell | Fibromyalgia | Nail-Patella Syndrome | Usher Syndrome Type I | Ganglioglioma | Aicardi-Goutieres Syndrome | Osteosclerosis | Hoyeraal-Hreidarsson Syndrome | Bronchiolitis | Angioedema, Acquired | Maple Syrup Urine Disease | Vestibular Disease | Coffin-Lowry Syndrome | Usher Syndrome Type II | Paternal Uniparental Disomy Of Chromosome 14 | Congenital Central Hypoventilation Syndrome | Hepatoblastoma | Erythromelalgia | Hyperphosphatasia With Intellectual Disability Syndrome 4 | Sotos Syndrome | Encephalitis, Tick-borne | Spondylocarpotarsal Synostosis Syndrome | Cysticercosis | Niemann-Pick Disease, Type C | Adenoma, Villous | Acute Myeloid Leukemia | Hidradenitis | Hereditary Spastic Paraplegia | Coloboma | Chronic Kidney Disease | Gastritis, Atrophic | Ameloblastoma | Lymphangioleiomyomatosis | Glutathione Synthetase Deficiency | Hypercholesterolemia | Chronic Periodontitis | Hypoproteinemia, Hypercatabolic | Tic Disorder | Chorea-acanthocytosis | Mucormycosis | Ovarian Hyperstimulation Syndrome | Retinal Detachment | Hypospadias | Disseminated Intravascular Coagulation | Epidermal Nevus Syndrome | Schwannomatosis | Autoimmune Polyendocrine Syndrome | Lissencephaly 2 | Sialidosis Type I | Sleep Apnea | Gastroenteritis, Eosinophilic | Familial Thoracic Aortic Aneurysm | Varices | Withdrawal Syndrome | Vogt-Koyanagi-Harada Syndrome | Cherubism | Basal Cell Nevus Syndrome | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Hepatitis B, Chronic | Prostatitis | Hypertrophy | Usher Syndrome Type III | Primary Biliary Cholangitis | Thalassemia, Beta | Galactosemia | Neutrophilia | Castleman Disease | Wilson's Disease | Cardiac Sarcoidosis | Pneumothorax | Galactosialidosis | Adenoid Cystic Carcinoma | Agranulocytosis | Retinopathy, Diabetic | Hypohidrotic Ectodermal Dysplasia, X-linked | Microcephaly | Rash | Hyperkalemic Periodic Paralysis | Polycystic Kidney, Autosomal Recessive | Monilethrix | Dementia | Shprintzen-Goldberg Syndrome | Epicondylitis | Large Granular Lymphocytic Leukemia | Waardenburg Syndrome Type 2 | Pleural Tuberculosis | Microcephalic Osteodysplastic Primordial Dwarfism, Type I | Chromosome 16p11.2 Deletion Syndrome | Sulfite Oxidase Deficiency | Thanatophoric Dysplasia Type 1 | Heroin Dependence | Combined Malonic And Methylmalonic Acidemia | GLUT1 Deficiency Syndrome | Bone Marrow Necrosis | PASLI Disease | Myotonia | Hyperinsulinism-hyperammonemia Syndrome | Sertoli Cell-only Syndrome | Common Variable Immunodeficiency | Osmotic Demyelination Syndrome | Glycogen Storage Disease | Subcortical Band Heterotopia | Vulvovaginitis | Methylmalonic Acidemia | Chediak-Higashi Syndrome | Postpartum Depression | Multiple Sulfatase Deficiency | Cystitis, Interstitial | Duodenal Atresia | Fuchs Dystrophy | Gerstmann-Straussler-Scheinker Syndrome | Spondylocostal Dysostosis | Spinocerebellar Ataxia Type 7 | Carney-Stratakis Syndrome | Epilepsy | B-cell Prolymphocytic Leukemia | Melnick-Needles Syndrome | Acute Motor Axonal Neuropathy | Connective Tissue Disorders | Hereditary Hemorrhagic Telangiectasia Type 2 | Measles | Encephalitis | Long QT Syndrome Type 1 | Persistent Truncus Arteriosus | Erythrokeratodermia Variabilis | Constipation | Corneal Edema | C3 Glomerulonephritis | Eczema | Lupus Erythematosus | T-cell Leukemia | Prolymphocytic Leukemia | Antiphospholipid Syndrome | Strabismus | Pneumonia, Mycoplasma | Meningioma, Benign | Congenital Dyserythropoietic Anemia Type 4 | Chromosome 5q Deletion Syndrome | Conduct Disorder | Chondrosarcoma | Acute Anterior Uveitis | Knobloch Syndrome | Sclerosteosis | Gallstones | Eclampsia | Hypopituitarism | Borjeson-Forssman-Lehmann Syndrome | Pure Autonomic Failure | Anorexia Nervosa | Melanoma | Osteoporosis | Epidermolysis Bullosa Acquisita | Macular Degeneration | SAPHO Syndrome | Glomerulonephritis, Membranoproliferative | Guillain-Barre Syndrome | Down Syndrome | Long QT Syndrome Type 3 | Hepatitis, Chronic | Otitis Media | Jalili Syndrome | Ebstein Anomaly | Presbycusis | Papillon-Lefevre Syndrome | Amblyopia | Granular Corneal Dystrophy Type 1 | Pneumoconiosis | Non-small Cell Lung Cancer | Rubinstein-Taybi Syndrome | Atelosteogenesis Type 2 | Uremic Pruritus | Polyneuropathy | Pityriasis Rubra Pilaris | Senior-Loken Syndrome | Intestinal Pseudo-obstruction | Hemimegalencephaly | Fibrodysplasia Ossificans Progressiva | Congenital Nystagmus | Keratopathy | Hyperbilirubinemia, Neonatal | Congenital Fiber-type Disproportion Myopathy | Familial Dysautonomia | Marinesco-Sjogren Syndrome | Exotropia | Acrodysostosis | Hemolytic Anemia | Hepatitis, Autoimmune | Epidermodysplasia Verruciformis | Chitayat Syndrome | Lipodystrophy | Iron Metabolism Disorders | Astrocytoma, Anaplastic | Reflex Epilepsy | Glioblastoma | Beckwith-Wiedemann Syndrome | Adenomatoid Tumor | Angioedema, Hereditary | Cystinuria | Charcot-Marie-Tooth Disease Type 4B1 | Osteogenesis Imperfecta Type II | Pyruvate Dehydrogenase Deficiency | Meningitis | Amyloidosis | Osteopathia Striata With Cranial Sclerosis | Hereditary Neuropathy With Liability To Pressure Palsies | Nanophthalmos | PHARC Syndrome | Metachromatic Leukodystrophy | Weill-Marchesani Syndrome | Liddle Syndrome | Acute Leukemia | Scabies | Papilledema | Homocystinuria | Pneumonia, Bacterial | Asphyxia Neonatorum | Rothmund-Thomson Syndrome | Sarcoidosis | Fraser Syndrome | Best Macular Dystrophy | Pierre Robin Syndrome | Poretti-Boltshauser Syndrome | Poikiloderma With Neutropenia | Sclerosteosis 2 | Tricho-hepato-enteric Syndrome | Adenosine Deaminase 2 Deficiency | Paroxysmal Kinesigenic Dyskinesia | Chondrodysplasia Punctata 2, X-linked Dominant | Ischemia | Conjunctivitis | Microvillus Inclusion Disease | Pemphigus | Pyruvate Carboxylase Deficiency Disease | Hypertelorism | Graves Disease | Charcot-Marie-Tooth Disease Type 4 | Rhinitis | Hyperinsulinemia | Episodic Ataxia Type 1 | Autosomal Recessive Spastic Paraplegia Type 35 | Ophthalmoplegia | Carbonic Anhydrase VA Deficiency | Chronic Beryllium Disease | Mosaic Variegated Aneuploidy Syndrome 2 | Methylmalonic Aciduria And Homocystinuria, CblC Type | Isobutyryl-CoA Dehydrogenase Deficiency | Blastoma, Pleuropulmonary | Familial Exudative Vitreoretinopathy | Porencephaly | Splenomegaly | Pupil Disorders | Heterotopic Ossification | Hypertension, Pulmonary | Amelogenesis Imperfecta | Beare-Stevenson Syndrome | Acromicric Dysplasia | Skin Carcinoma | Proteus Syndrome | Neuromuscular Disorders | Spinocerebellar Ataxia Type 12 | Medulloblastoma | Maternally Inherited Diabetes And Deafness | Rosacea | Hypercalcemia | Localized Scleroderma | Lamellar Ichthyosis | Hyperkeratosis | Neurocutaneous Melanocytosis | Rhabdoid Tumor | Hyperparathyroidism, Primary | Autosomal Recessive Spastic Paraplegia Type 75 | Lafora Disease | Glycogen Storage Disease Type 5 | Neuroleptic Malignant Syndrome | Adenocarcinoma | Primary Lateral Sclerosis | Aneurysm, Thoracic Aortic | Diarrhea | Familial Hyperaldosteronism | Shock, Cardiogenic | Swine Influenza | Cri-du-chat Syndrome | Cerebral Cavernous Malformations | Early Infantile Epileptic Encephalopathy 28 | Spinocerebellar Ataxia Type 40 | Sorsby Fundus Dystrophy | Chronic Granulomatous Disease | Esophagitis | Primary Cutaneous Amyloidosis | Nutrition Disorders | Ocular Albinism Type 1 | Cryoglobulinemia | Noonan Syndrome-like Disorder With Loose Anagen Hair | Congenital Hypofibrinogenemia | Prader-Willi Syndrome | Osteogenesis Imperfecta Type I | Toxic Epidermal Necrolysis | Chondroma | Osteomalacia | Zellweger Syndrome | Crimean-Congo Hemorrhagic Fever | Muscle Wasting | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Spermatocele | Chiari Malformation Type I | Diabetic Neuropathy | Prune Belly Syndrome | Platelet Disorders | CHARGE Syndrome | Muckle-Wells Syndrome