Powered by AI technology, BDE-Bio combines massive literature, patent and comprehensive biological data to accurately screen and predict disease diagnosis and therapeutic targets / biomarkers. It can automatically generate target research reports with one click, making it an indispensable tool for pharmaceutical research and development.
BDE-Bio
TARGET PRECISE DISCOVERY
Product Introduction
BDE-Bio achieves precise screening and prediction of new targets by combining 24-hour continuous updates, massive literature texts, comprehensive biological databases, and large-scale multi-omics data, and can provide the basis and logic for target discovery.
1) Capture: 24-hour monitoring of Pubmed, 24 public databases (genecard, drugbank, pubchem, etc.), real-time inbound parsing.
2) Extraction: It can extract basic information about the target, protein structure, biological mechanism of the target, drug resistance of the target, disease correlation, etc.
3) Analysis: Summarize long content, generate reports with one click, recommend target points, etc.
Target Prediction
Predicting targets that can successfully enter the clinical trial stage and ensuring that lead compounds based on predicted targets can successfully break through the PCC stage within an estimated time frame.
Target-based Drug Prediction
Predicting the difficulty level of target-based drug development provides a basis for assessing the value of target exploration.
Disease-Related Target Prediction
Predicting key targets for specific diseases and provide a basis for drug development for rare diseases and difficult and complicated diseases.
Common Targets and Diseases
Targets
ABCB1 | ABCG2 | ACE2 | AHR | AKT1 | ALK | AR | ATM | BAX | BCL2 | BCL2L1 | BECN1 | BRAF | BRCA1 | CAMP | CASP3 | CASP9 | CCL5 | CCND1 | CD274 | CD4 | CD8A | CDH1 | CDKN1A | CDKN2A | CREB1 | CXCL8 | CXCR4 | DNMT1 | EGF | EGFR | EP300 | ERBB2 | EREG | ESR1 | EZH2 | FN1 | FOXO3 | HDAC9 | HGF | HMGB1 | HSP90AA1 | HSPA4 | HSPA5 | IDO1 | IFNA1 | IGF1 | IGF1R | IL17A | IL6 | INS | JUN | KRAS | MAPK1 | MAPK14 | MAPK3 | MAPK8 | MAPT | MCL1 | MDM2 | MET | MMP9 | MTOR | MYC | NFE2L2 | NLRP3 | NOTCH1 | PARP1 | PCNA | PDCD1 | PLK1 | PRKAA1 | PRKAA2 | PTEN | PTGS2 | PTK2 | RELA | SIRT1 | SLTM | SMAD4 | SOD1 | SQSTM1 | SRC | STAT1 | STAT3 | STAT5A | TAK1 | TERT | TLR4 | TNF | TP53 | TXN | VEGFA | YAP1
Diseases
McKusick Type Metaphyseal Chondrodysplasia | Left Ventricular Noncompaction | Spondylocarpotarsal Synostosis Syndrome | Neuromyotonia | Congenital Myasthenic Syndrome | Ophthalmia, Sympathetic | Chediak-Higashi Syndrome | Cystitis, Interstitial | Anorectal Fistula | Chorioretinitis | Melanoma | Charcot-Marie-Tooth Disease Type 2T | Sarcoidosis, Pulmonary | Chromosome 5q Deletion Syndrome | Cataract | Tyrosine Hydroxylase Deficiency | Renpenning Syndrome | 3-methylglutaconic Aciduria Type IV | Renal Tubular Acidosis | Esotropia | Exostoses | Short-chain Acyl-CoA Dehydrogenase Deficiency | Autosomal Recessive Bestrophinopathy | Spinocerebellar Ataxia Type 40 | Vascular Calcification | Hermansky-Pudlak Syndrome | Aceruloplasminemia | Amelogenesis Imperfecta | Keratosis, Actinic | Gastroenteritis | 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Pneumoconiosis | Hereditary Xerocytosis | Holoprosencephaly | Headache | Fibrillation, Atrial | Gaucher Disease | Macular Corneal Dystrophy | Osteochondrosis | Epidermolytic Palmoplantar Keratoderma | Non-proliferative Diabetic Retinopathy | Macular Corneal Dystrophy Type 1 | Duane Retraction Syndrome | Mosaic Variegated Aneuploidy Syndrome 2 | Paraplegia | Hyperparathyroidism, Primary | Bursitis | Acrodermatitis Enteropathica | Fukuyama Congenital Muscular Dystrophy | Pulmonary Capillary Hemangiomatosis | Alazami Syndrome | Corneal Edema | Myelodysplasia | Eating Disorder | Acute Coronary Syndrome | Polymicrogyria | Epithelial-myoepithelial Carcinoma | Skin Papilloma | Chronic Myeloid Leukemia | Fuchs Dystrophy | Tinea | Membranous Nephropathy | Demyelinating Diseases | Pseudo-pseudohypoparathyroidism | Alcoholism | Congenital Stromal Corneal Dystrophy | Adenosine Deaminase 2 Deficiency | Maternally Inherited Diabetes And Deafness | Rothmund-Thomson Syndrome | Chronic Granulomatous Disease, X-linked | Infantile Neuroaxonal Dystrophy | Charcot-Marie-Tooth Disease Type 3 | Conjunctivitis, Allergic | Porencephaly | Silicosis | Waardenburg Syndrome Type 2A | Yellow Fever | Hereditary Mixed Polyposis Syndrome | Graves Disease | Multiple Sclerosis, Relapsing-remitting | Oligoasthenoteratozoospermia | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Fabry's Disease | Renal Medullary Carcinoma | Protein C Deficiency | Familial Hemiplegic Migraine | Hypersomnia | X-linked Charcot-Marie-Tooth Disease | Keratitis-ichthyosis-deafness Syndrome | Congenital Stationary Night Blindness | Restless Legs Syndrome | Encephalitis, Tick-borne | Hypophosphatasia | Hereditary Coproporphyria | Thyroiditis, Autoimmune | Exotropia | Meningitis | Patent Ductus Arteriosus | Hypoglycemia | Sarcoma, Alveolar Soft Part | Thyroiditis | Absence Epilepsy | Beckwith-Wiedemann Syndrome | Kernicterus | Stuttering | Rosacea | Bartsocas-Papas Syndrome | Riboflavin Transporter Deficiency Neuronopathy | Language Disorders | Lymphoma, Mantle Cell | Centronuclear Myopathy | Strabismus | Posterior Polar Cataract | Heart Failure | Charcot-Marie-Tooth Disease, Type 2A | Kohlschutter-Tonz Syndrome | Purpura, Thrombotic Thrombocytopenic | Glaucoma | Proteus Syndrome | Urofacial Syndrome | Hepatic Veno-occlusive Disease | Chorea-acanthocytosis | Glomerulonephritis, Membranous | Chronic Leukemia | Polycythemia Vera | Spinocerebellar Ataxia Type 8 | Kabuki Syndrome 2 | Cavitary Optic Disc Anomalies | Syndactyly | D-2-Hydroxyglutaric Aciduria | Frank-ter Haar Syndrome | Acanthosis Nigricans | Megaloblastic Anemia | Charcot-Marie-Tooth Disease, Type 2C | Seborrheic Dermatitis | Leukoplakia, Oral | Geleophysic Dysplasia | Adenoma, Villous | Glycogen Storage Disease Type 5 | Seizures-scoliosis-macrocephaly Syndrome | Chanarin-Dorfman Syndrome | Autoimmune Hemolytic Anemia | Pierson Syndrome | Thrombocytopenia | Cholesteryl Ester Storage Disease | Pneumonia, Bacterial | Asthma, Exercise-induced | Congenital Hypofibrinogenemia | Prurigo Nodularis | Acrodermatitis | Congenital Heart Defects | Generalized Epilepsy With Febrile Seizures Plus | Hereditary Folate Malabsorption | Platelet Disorders | Impetigo | McLeod Syndrome | Acute Lung Injury | Goiter | Atrioventricular Septal Defect | Myhre Syndrome | PASLI Disease | Lymphoma, AIDS-related | Postpoliomyelitis Syndrome | Leri-Weill Dyschondrosteosis | Emery-Dreifuss Muscular Dystrophy | Joubert Syndrome | Medulloblastoma | Cervical Dystonia | Best Macular Dystrophy | Pilomatrix Carcinoma | Hyperandrogenemia | Zollinger-Ellison Syndrome | Autism Spectrum Disorders | Cardiospondylocarpofacial Syndrome | Hepatic Steatosis | Hyperphenylalaninemia | Osteoarthritis | Aplasia Cutis Congenita | Esophagitis | Malignant Peripheral Nerve Sheath Tumor | Hemangioma | Anti-NMDA Receptor Encephalitis | Farber Disease | Scapuloperoneal Spinal Muscular Atrophy | Dystrophy, Cone-rod | Delirium | 3-methylglutaconic Aciduria Type I | Hyperlipidemia, Familial Combined | Withdrawal Syndrome | Encephalocele | Cranial Nerve Disease | Epidermolytic Hyperkeratosis | Pancreatitis | Pompe Disease | Kallmann Syndrome | Ichthyosis Bullosa Of Siemens | Congenital Disorders Of Glycosylation | Scleritis | Vulvovaginitis | Light Chain Amyloidosis | Polycystic Ovary Syndrome | Myoclonus | Bacterial Meningitis | Kaposiform Hemangioendothelioma | Encephalopathy, Ethylmalonic | Prolidase Deficiency | Sick Sinus Syndrome | Liebenberg Syndrome | Lathosterolosis | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | Primary Progressive Nonfluent Aphasia | Carotid Artery Disease | Pelvic Inflammatory Disease | Wolfram Syndrome 2 | Progressive Familial Intrahepatic Cholestasis | Dyskeratosis Congenita | Bainbridge-Ropers Syndrome | Blomstrand Osteochondrodysplasia | Mandibuloacral Dysplasia With Type A Lipodystrophy | Ollier Disease | Motor Neuron Diseases | Autoimmune Autonomic Ganglionopathy | Granular Corneal Dystrophy Type 1 | Chondrosarcoma | Hypertrophy | Pitt-Hopkins Syndrome | Hypertensive Retinopathy | Schnitzler Syndrome | Klinefelter Syndrome | Congenital Lipoid Adrenal Hyperplasia | Cocaine-Related Disorders | Chronic Beryllium Disease | Barrett Esophagus | Sponastrime Dysplasia | Xeroderma Pigmentosum | Bone Marrow Necrosis | TARP Syndrome | Angioedema, Hereditary | Conjunctivitis | Charcot-Marie-Tooth Disease Type 2D | Acute Chest Syndrome | Aplastic Anemia | Lattice Corneal Dystrophy | Kashin-Beck Disease | Adams-Oliver Syndrome | Glycogen Storage Disease | Juvenile Myoclonic Epilepsy | Metachondromatosis | VACTERL/VATER Association | Hartnup Disease | Subacute Sclerosing Panencephalitis | Congenital Muscular Dystrophy | Mannosidase Deficiency Diseases | Neuronal Ceroid Lipofuscinosis | Rhabdomyosarcoma, Embryonal | Measles | Jaundice, Obstructive | Oligospermia | Constipation | Vaginitis | Schindler Disease | Hypereosinophilic Syndrome | Amebiasis | Micropenis | Congenital Adrenal Hyperplasia 1 | Vitiligo | Pfeiffer Syndrome | Idiopathic Pulmonary Fibrosis | Premenstrual Syndrome | Gingivitis | Actinomycetoma | Anencephaly | T-cell Prolymphocytic Leukemia | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Cockayne Syndrome | Ectrodactyly | Congenital Bilateral Absence Of Vas Deferens | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Desmosterolosis | Sturge-Weber Syndrome | Holt-Oram Syndrome | Pulmonary Alveolar Microlithiasis | Heart Septal Defects | Cancer, Prostate | Acute Myeloid Leukemia | Birk-Barel Syndrome | Presbyopia | Charcot-Marie-Tooth Disease, Type 6 | Chordoma | Spermatocele | Alpha-mannosidosis | Cat Eye Syndrome | Familial Exudative Vitreoretinopathy | Blepharophimosis Syndrome | Dentinogenesis Imperfecta | Temtamy Preaxial Brachydactyly Syndrome | Schizophrenia | Tetanus | Charcot-Marie-Tooth Disease Type 4 | Lassa Fever | Cancer, Colon | Congenital Central Hypoventilation Syndrome | Diabetes | Treacher Collins Syndrome | Transient Bullous Dermolysis Of The Newborn | Trachoma | Prune Belly Syndrome | Primary Carnitine Deficiency | Retinal Detachment | Metachromatic Leukodystrophy | Cancer, Brain | Snyder-Robinson Syndrome | Neuroendocrine Cancer | Gastroenteritis, Eosinophilic | Pantothenate Kinase-associated Neurodegeneration | Osteogenesis Imperfecta | CEDNIK Syndrome | Nasodigitoacoustic Syndrome | Hyperoxaluria | Myasthenia | Familial Hyperaldosteronism | Burn-McKeown Syndrome | Anemia | Ureteropelvic Junction Obstruction | Glycogen Storage Disease Type 9 | Microphthalmia | 3-methylglutaconic Aciduria | Necrobiosis Lipoidica | Cataplexy | Paraganglioma | Congenital Sodium Diarrhea | Dupuytren Disease | Mitochondrial DNA Depletion Syndrome, Myopathic Form | Dominant Optic Atrophy | Anthrax | Alexander Disease | Panic Disorder | Hyperekplexia | Adult Polyglucosan Body Disease | Cenani-Lenz Syndactyly Syndrome | Pseudohypoaldosteronism | Lamellar Ichthyosis | Optic Nerve Hypoplasia, Bilateral | Cole-Carpenter Syndrome | Systemic Mastocytosis | Lymphedema-distichiasis Syndrome | Atelosteogenesis Type 1 | Lichen Planus | Pseudomyxoma Peritonei | Tonsillitis | Thyroid Dysgenesis | HIBCH Deficiency | Miyoshi Myopathy | Phenylketonuria II | Waardenburg Syndrome Type 4A | Motion Sickness | Long QT Syndrome Type 2 | Methemoglobinemia Type IV | Muscular Dystrophy | Astrocytoma | Angiodysplasia | Primary Hyperoxaluria Type 1 | Pierre Robin Syndrome | Hydronephrosis | Lewy Body Dementia | Viral Meningitis | Crigler-Najjar Syndrome | Silver-Russell Syndrome | Cholangitis | Corneal Neovascularization | Crouzon Syndrome With Acanthosis Nigricans | Tendinitis | Epiphyseal Chondrodysplasia, Miura Type | Sotos Syndrome | Fuchs Heterochromic Iridocyclitis | Sarcoma | Cluster Headache | Focal Cortical Dysplasia Type 2 | Multisystemic Smooth Muscle Dysfunction Syndrome | Microcephalic Primordial Dwarfism | Hyperkeratosis | Familial Glucocorticoid Deficiency | CDKL5 Deficiency Disorder | Pancreatitis, Chronic | Colon Adenoma | Colorectal Adenoma | Adenoma, Pituitary | Bernard-Soulier Syndrome | Loeys-Dietz Syndrome | Sialoadenitis | Fetal Akinesia Deformation Sequence | Epidermolytic Ichthyosis, Annular | Hemangioblastoma | Glutaric Aciduria Type 3 | Osteosarcoma | Early Infantile Epileptic Encephalopathy 13 | Metaphyseal Chondrodysplasia, Schmid Type | Cardiomyopathy, Dilated, 1L | IgA Nephropathy | Johanson-Blizzard Syndrome
