Powered by AI technology, BDE-Bio combines massive literature, patent and comprehensive biological data to accurately screen and predict disease diagnosis and therapeutic targets / biomarkers. It can automatically generate target research reports with one click, making it an indispensable tool for pharmaceutical research and development.
BDE-Bio
TARGET PRECISE DISCOVERY
Product Introduction
BDE-Bio achieves precise screening and prediction of new targets by combining 24-hour continuous updates, massive literature texts, comprehensive biological databases, and large-scale multi-omics data, and can provide the basis and logic for target discovery.
1) Capture: 24-hour monitoring of Pubmed, 24 public databases (genecard, drugbank, pubchem, etc.), real-time inbound parsing.
2) Extraction: It can extract basic information about the target, protein structure, biological mechanism of the target, drug resistance of the target, disease correlation, etc.
3) Analysis: Summarize long content, generate reports with one click, recommend target points, etc.
Target Prediction
Predicting targets that can successfully enter the clinical trial stage and ensuring that lead compounds based on predicted targets can successfully break through the PCC stage within an estimated time frame.
Target-based Drug Prediction
Predicting the difficulty level of target-based drug development provides a basis for assessing the value of target exploration.
Disease-Related Target Prediction
Predicting key targets for specific diseases and provide a basis for drug development for rare diseases and difficult and complicated diseases.
Common Targets and Diseases
Targets
ABCB1 | ABCG2 | ACE2 | AHR | AKT1 | ALK | AR | ATM | BAX | BCL2 | BCL2L1 | BECN1 | BRAF | BRCA1 | CAMP | CASP3 | CASP9 | CCL5 | CCND1 | CD274 | CD4 | CD8A | CDH1 | CDKN1A | CDKN2A | CREB1 | CXCL8 | CXCR4 | DNMT1 | EGF | EGFR | EP300 | ERBB2 | EREG | ESR1 | EZH2 | FN1 | FOXO3 | HDAC9 | HGF | HMGB1 | HSP90AA1 | HSPA4 | HSPA5 | IDO1 | IFNA1 | IGF1 | IGF1R | IL17A | IL6 | INS | JUN | KRAS | MAPK1 | MAPK14 | MAPK3 | MAPK8 | MAPT | MCL1 | MDM2 | MET | MMP9 | MTOR | MYC | NFE2L2 | NLRP3 | NOTCH1 | PARP1 | PCNA | PDCD1 | PLK1 | PRKAA1 | PRKAA2 | PTEN | PTGS2 | PTK2 | RELA | SIRT1 | SLTM | SMAD4 | SOD1 | SQSTM1 | SRC | STAT1 | STAT3 | STAT5A | TAK1 | TERT | TLR4 | TNF | TP53 | TXN | VEGFA | YAP1
Diseases
Primary Hyperoxaluria | Pernicious Anemia | Pontocerebellar Hypoplasia Type 2 | Hyper IgE Syndrome | Spinocerebellar Ataxia Type 8 | Gingivitis | Early Infantile Epileptic Encephalopathy 4 | Syncope | Echinococcosis | 3-M Syndrome | Chronic Thromboembolic Pulmonary Hypertension | Autosomal Recessive Spastic Paraplegia Type 54 | Glycogen Storage Disease Type 0, Muscle | Constipation | Chondrodysplasia Punctata 1, X-linked Recessive | Majeed Syndrome | Hypoglycemia | Wiskott-Aldrich Syndrome | Reye Syndrome | Spinocerebellar Ataxia Type 23 | Atrioventricular Septal Defect | Retinitis | Chromosome 17q21.31 Deletion Syndrome | Methemoglobinemia | Creatine Deficiency Syndrome Due To AGAT Deficiency | Pyruvate Kinase Deficiency | Congenital Stromal Corneal Dystrophy | Leri-Weill Dyschondrosteosis | Pontocerebellar Hypoplasia | Gastrointestinal Disorders | Lipodystrophy | Juvenile Myelomonocytic Leukemia | Familial Partial Lipodystrophy | Hepatorenal Syndrome | Werner's Syndrome | Dengue Hemorrhagic Fever | Fascioliasis | Tyrosinemia Type 2 | VACTERL Association | Pituitary Stalk Interruption Syndrome | Arteriovenous Malformations | Prostatitis | Familial Hypobetalipoproteinemia | Trigonocephaly | Sialidosis Type I | Trismus-pseudocamptodactyly Syndrome | Microcephalic Primordial Dwarfism | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Carcinoma In Situ | Cerebrovascular Disorders | Coronary Heart Disease | Skin Carcinoma | Usher Syndrome | Long-chain 3-hydroxyacyl-coenzyme A Dehydrogenase Deficiency | Leukocyte Adhesion Deficiency Type 1 | Jacobsen Syndrome | Glutaric Aciduria Type 2 | Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form | Lipid Storage Myopathy | Autism | IgA Deficiency | Hyperbilirubinemia | Multiple Sclerosis, Secondary Progressive | Superficial Spreading Melanoma | Dubin-Johnson Syndrome | Zellweger Syndrome | Porokeratosis | Lipid Storage Diseases | Carey-Fineman-Ziter Syndrome | Danon Disease | Gangliosidosis | Lipid Metabolism Disorders | Lymphoma, B-cell | Multicystic Renal Dysplasia | Dysferlinopathy | Mucolipidosis | Pfeiffer Syndrome | Mosaic Variegated Aneuploidy Syndrome 2 | Colitis, Collagenous | GM2-gangliosidosis AB Variant | Fibrosis | Partington Syndrome | Spinocerebellar Ataxia Type 16 | Bicuspid Aortic Valve | Hyperhomocysteinemia | Glaucomatocyclitic Crisis | Cantu Syndrome | Optic Neuropathy, Anterior Ischemic | Spinocerebellar Ataxia Type 28 | Adenylosuccinate Lyase Deficiency | Microphthalmia | Cleidocranial Dysplasia | Carcinoma, Squamous Cell | Thrombotic Microangiopathy | McCune-Albright Syndrome | Osteogenesis Imperfecta Type V | Hereditary Inclusion Body Myopathy | Stromal Corneal Dystrophy | Snyder-Robinson Syndrome | Mucormycosis | Incontinentia Pigmenti | Otitis Externa | Vici Syndrome | Periodontitis | Cancer, Skin | Hypohidrotic Ectodermal Dysplasia | Retinal Diseases | Empyema | Rhabdoid Tumor | Fraser Syndrome | Celiac Disease | Pituitary Dwarfism | Pitt-Hopkins Syndrome | Spinocerebellar Ataxia Type 10 | Lateral Meningocele Syndrome | Pulmonary Stenosis | Hereditary Hemorrhagic Telangiectasia Type 2 | Familial Mediterranean Fever | Tyrosine Hydroxylase Deficiency | Galactosialidosis | Preaxial Polydactyly | Benign Familial Neonatal Convulsions | Corneal Ulcer | Endophthalmitis | Tardive Dyskinesia | Diabetic Neuropathy | Acromegaly | Infantile Liver Failure Syndrome 1 | Choroideremia | Congenital Muscular Dystrophy | Holoprosencephaly | LEOPARD Syndrome | Greenberg Dysplasia | Primary Hyperoxaluria Type 3 | Malignant Peripheral Nerve Sheath Tumor | Oculocutaneous Albinism | Neuroectodermal Tumors, Primitive | Agammaglobulinemia | Inflammatory Bowel Disease | Prolactinoma | Macrophagic Myofasciitis | Fucosidosis | Epilepsy | Sturge-Weber Syndrome | Connective Tissue Disorders | Lymphangioma | Cirrhosis | Marfan Syndrome | Hepatitis, Chronic | Hereditary Sensory And Autonomic Neuropathy | Vaginitis | Nephropathy | Chanarin-Dorfman Syndrome | Spinocerebellar Ataxia Type 20 | Fragile X Syndrome | Burn-McKeown Syndrome | Cramp Fasciculation Syndrome | Bullous Pemphigoid | Hereditary Folate Malabsorption | Presbycusis | Seizures-scoliosis-macrocephaly Syndrome | Genee-Wiedemann Syndrome | Crohn's Disease | Lattice Corneal Dystrophy Type 1 | Nephrotic Syndrome | Rheumatic Heart Disease | Congenital Adrenal Hyperplasia | X-linked Myotubular Myopathy | Congenital Dyserythropoietic Anemia Type 4 | Hypogammaglobulinemia | Hypotrichosis | Metanephric Adenoma | Central Retinal Artery Occlusion | Temporal Lobe Epilepsy | Stroke, Ischemic | Hypertensive Retinopathy | Reflex Epilepsy | Craniopharyngioma | Adenosine Deaminase 2 Deficiency | Pneumonia, Viral | Ovarian Sex Cord-stromal Tumor | Acquired Partial Lipodystrophy | Barrett Esophagus | Tetanus | Silver-Russell Syndrome | Acute Motor Axonal Neuropathy | Atelosteogenesis Type 1 | Focal Segmental Glomerulosclerosis | Fundus Albipunctatus | HELLP Syndrome | Esotropia | Congenital Hemolytic Anemia | Sickle Cell Anemia | Paternal Uniparental Disomy Of Chromosome 14 | Benign Recurrent Intrahepatic Cholestasis 1 | Myopathy | Oculopharyngeal Muscular Dystrophy | Alkaptonuria | Atopy | Ebstein Anomaly | Kindler Syndrome | Ulcerative Colitis | Chorioretinitis | Herpes Simplex Dermatitis | Androgenic Alopecia | Babesiosis | Nestor-Guillermo Progeria Syndrome | Muckle-Wells Syndrome | Tetraplegia | Chromosome 8q21.11 Deletion Syndrome | Heart Block | Cervicitis | Zimmermann-Laband Syndrome | Encephalocele | High Molecular Weight Kininogen Deficiency | Chronic Granulomatous Disease, X-linked | Paroxysmal Nocturnal Hemoglobinuria | Rhabdomyosarcoma, Embryonal | ADNP Syndrome | Neurocutaneous Melanocytosis | Ovarian Hyperstimulation Syndrome | Primary Progressive Nonfluent Aphasia | Hashimoto Thyroiditis | Hemolytic Uremic Syndrome | Eccrine Porocarcinoma | Aspartylglycosaminuria | Proteus Syndrome | Lathosterolosis | Patent Foramen Ovale | Jalili Syndrome | Sickle Cell Disease | Postpoliomyelitis Syndrome | Conduct Disorder | Pure Red Cell Aplasia | Galloway-Mowat Syndrome | Sarcosinemia | Cutaneous T-cell Lymphoma | Holt-Oram Syndrome | Sarcoma, Endometrial Stromal | Primary Pigmented Nodular Adrenocortical Disease | Non-proliferative Diabetic Retinopathy | Angioedema, Acquired | Costello Syndrome | Charcot-Marie-Tooth Disease Type 2E | Antley-Bixler Syndrome | Myhre Syndrome | Epidermolytic Palmoplantar Keratoderma | Anorectal Malformations | Corneal Dystrophy | Asthma | Spinocerebellar Ataxia Type 40 | Axenfeld-Rieger Syndrome | Split Hand-foot Malformation | Myelodysplasia | Lamellar Ichthyosis | Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress | Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy | Progressive Familial Intrahepatic Cholestasis Type 2 | Diabetic Macular Edema | Hypervalinemia | Oligoastrocytoma | Stickler Syndrome | Primary Sclerosing Cholangitis | Anti-NMDA Receptor Encephalitis | Adrenal Insufficiency | Neuromyelitis Optica | Angelman Syndrome | Eczema | Autoimmune Polyendocrinopathy Syndrome Type I | Paraganglioma, Carotid Body | CREST Syndrome | Down Syndrome | Obsessive-compulsive Disorder | Lymphoproliferative Disorders | Lymphoma, Primary Cutaneous Anaplastic Large Cell | Chronic Periodontitis | Desmosterolosis | Persistent Mullerian Duct Syndrome | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | Erythematotelangiectatic Rosacea | Nephrocalcinosis | Scleroderma | Heroin Dependence | Spondylo-ocular Syndrome | Trimethylaminuria | Cancer, Lung | Bartsocas-Papas Syndrome | Pityriasis Rubra Pilaris | Carcinoid Syndrome | Cholera | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Citrullinemia | Glycogen Storage Disease Type 6 | Anorectal Fistula | Batten Disease | Venous Insufficiency | Porphyria | McLeod Syndrome | Monilethrix | Rotor Syndrome | Marshall-Smith Syndrome | Cervical Dystonia | Gerstmann-Straussler-Scheinker Syndrome | NGLY1 Deficiency | Hypercholesterolemia, Familial | Neurodevelopmental Disorders | Papillorenal Syndrome | Blue Rubber Bleb Nevus Syndrome | 3-methylglutaconic Aciduria Type I | Metatropic Dysplasia | Tinea Versicolor | Smith-Magenis Syndrome | Hairy Cell Leukemia | Glycogen Storage Disease Type 9 | Congenital Heart Block | Camurati-Engelmann Disease | Androgen Insensitivity | Glucagonoma | Cerebral Amyloid Angiopathy | Photosensitivity | Myosin Storage Myopathy | Vestibular Disease | Acrodysostosis | Sepiapterin Reductase Deficiency | Meningeal Melanocytoma | Harlequin Ichthyosis | Ventricular Septal Defect | Papillon-Lefevre Syndrome | Cryopyrin-associated Periodic Syndromes | Nail-Patella Syndrome | Tumoral Calcinosis | Pemphigus | Phosphoenolpyruvate Carboxykinase Deficiency, Cytosolic | Cholangitis | Fuchs Dystrophy | Early Infantile Epileptic Encephalopathy 13 | Myoclonic Atonic Epilepsy | Hypotrichosis Simplex | Smoldering Myeloma | Sick Sinus Syndrome 1 | Alzheimer Disease, Late Onset | Psoriasis | Precocious Puberty | Pancreatitis, Chronic | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Arteriosclerosis | Renal Tubular Acidosis | Macular Corneal Dystrophy | Waardenburg Syndrome Type 1 | Neuropathy | Obesity | Encephalopathy, Ethylmalonic | Epidermolysis Bullosa Dystrophica | GATA2 Deficiency | Nephrotic Syndrome Type 1 | Colorectal Adenoma | LRBA Deficiency | Cockayne Syndrome | Congenital Dysfibrinogenemia | Spondylometaphyseal Dysplasia | Congenital Generalized Lipodystrophy | Dentinogenesis Imperfecta | Hypotonia-cystinuria Syndrome | Acrocallosal Syndrome | Torticollis | Infantile Refsum Disease | Benign Familial Infantile Seizures | Hypertelorism | Epidermal Nevus Syndrome | Congenital Dyserythropoietic Anemia Type 1 | Hyperacusis | Congenital Disorders Of Glycosylation | Spitzoid Melanoma | Poikiloderma With Neutropenia | Van Der Knaap Disease | Scapuloperoneal Spinal Muscular Atrophy | Cataract | Choroiditis | Granular Corneal Dystrophy | Shprintzen-Goldberg Syndrome | Cholelithiasis | Autism Spectrum Disorders | Progressive Encephalopathy-optic Atrophy Syndrome | Myelitis | X-linked Sideroblastic Anemia | Autoimmune Hemolytic Anemia | Woodhouse-Sakati Syndrome | Overactive Bladder | Amblyopia | Porphyria Cutanea Tarda | Ollier Disease | Hypokalemic Periodic Paralysis | Lymphedema | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Pure Autonomic Failure | Adenomyosis | Duodenal Atresia | Ameloblastoma | Alpers Syndrome | Methemoglobinemia Type IV
