Powered by AI technology, BDE-Bio combines massive literature, patent and comprehensive biological data to accurately screen and predict disease diagnosis and therapeutic targets / biomarkers. It can automatically generate target research reports with one click, making it an indispensable tool for pharmaceutical research and development.
BDE-Bio
TARGET PRECISE DISCOVERY
Product Introduction
BDE-Bio achieves precise screening and prediction of new targets by combining 24-hour continuous updates, massive literature texts, comprehensive biological databases, and large-scale multi-omics data, and can provide the basis and logic for target discovery.
1) Capture: 24-hour monitoring of Pubmed, 24 public databases (genecard, drugbank, pubchem, etc.), real-time inbound parsing.
2) Extraction: It can extract basic information about the target, protein structure, biological mechanism of the target, drug resistance of the target, disease correlation, etc.
3) Analysis: Summarize long content, generate reports with one click, recommend target points, etc.
Target Prediction
Predicting targets that can successfully enter the clinical trial stage and ensuring that lead compounds based on predicted targets can successfully break through the PCC stage within an estimated time frame.
Target-based Drug Prediction
Predicting the difficulty level of target-based drug development provides a basis for assessing the value of target exploration.
Disease-Related Target Prediction
Predicting key targets for specific diseases and provide a basis for drug development for rare diseases and difficult and complicated diseases.
Common Targets and Diseases
Targets
ABCB1 | ABCG2 | ACE2 | AHR | AKT1 | ALK | AR | ATM | BAX | BCL2 | BCL2L1 | BECN1 | BRAF | BRCA1 | CAMP | CASP3 | CASP9 | CCL5 | CCND1 | CD274 | CD4 | CD8A | CDH1 | CDKN1A | CDKN2A | CREB1 | CXCL8 | CXCR4 | DNMT1 | EGF | EGFR | EP300 | ERBB2 | EREG | ESR1 | EZH2 | FN1 | FOXO3 | HDAC9 | HGF | HMGB1 | HSP90AA1 | HSPA4 | HSPA5 | IDO1 | IFNA1 | IGF1 | IGF1R | IL17A | IL6 | INS | JUN | KRAS | MAPK1 | MAPK14 | MAPK3 | MAPK8 | MAPT | MCL1 | MDM2 | MET | MMP9 | MTOR | MYC | NFE2L2 | NLRP3 | NOTCH1 | PARP1 | PCNA | PDCD1 | PLK1 | PRKAA1 | PRKAA2 | PTEN | PTGS2 | PTK2 | RELA | SIRT1 | SLTM | SMAD4 | SOD1 | SQSTM1 | SRC | STAT1 | STAT3 | STAT5A | TAK1 | TERT | TLR4 | TNF | TP53 | TXN | VEGFA | YAP1
Diseases
Williams Syndrome | Hypocalcemia | Hypertension, Essential | Familial Exudative Vitreoretinopathy | Odonto-onycho-dermal Dysplasia | Hypotension, Orthostatic | Keratitis | Neovascular Glaucoma | Tuberculous Meningitis | Schizophrenia, Paranoid | Isovaleric Acidemia | Renal Dysplasia | Lupus Erythematosus | Pyruvate Carboxylase Deficiency Disease | Oculodentodigital Dysplasia | Fanconi Syndrome | Noonan Syndrome-like Disorder With Loose Anagen Hair | Cancer, Breast | Iron Metabolism Disorders | Osteogenesis Imperfecta Type II | Prolidase Deficiency | Syndactyly | Autosomal Recessive Spastic Paraplegia Type 54 | Pneumonia, Mycoplasma | Osteopathia Striata With Cranial Sclerosis | Hypotrichosis Simplex | Apert Syndrome | Multiple Epiphyseal Dysplasia | Exocrine Pancreatic Insufficiency | Neuronal Ceroid Lipofuscinosis | Carey-Fineman-Ziter Syndrome | Smith-Magenis Syndrome | Benign Hereditary Chorea | Sensory Neuropathy | Withdrawal Syndrome | Lentigo | Hepatoblastoma | Angelman Syndrome | Recurrent Respiratory Papillomatosis | Multifocal Motor Neuropathy | Leukoplakia, Oral | Coffin-Lowry Syndrome | Varices | Epidermolysis Bullosa Simplex With Mottled Pigmentation | B-cell Chronic Lymphocytic Leukemia | Panic Disorder | 5-oxoprolinase Deficiency | Hypothyroidism | Cutaneous T-cell Lymphoma | Gout | Hyperinsulinemic Hypoglycemia | Sclerosing Cholangitis | C3 Glomerulonephritis | Fragile X Syndrome | Poikiloderma With Neutropenia | Turner's Syndrome | Glutaric Aciduria Type 3 | Anorexia Nervosa | Familial Hypobetalipoproteinemia | Double Outlet Right Ventricle | Majeed Syndrome | Hypercholesterolemia, Familial | Meconium Ileus | 3-M Syndrome | Arts Syndrome | Microphthalmia | Juvenile Polyposis | Acromesomelic Dysplasia | Seminoma | Asplenia | Sturge-Weber Syndrome | Thrombosis | Chromosome 9q34.3 Deletion Syndrome | Still Disease | Craniosynostosis | Polycystic Kidney, Autosomal Recessive | Schwartz-Jampel-Aberfeld Syndrome | Optic Nerve Hypoplasia, Bilateral | Spina Bifida | Arteriovenous Malformations | Chronic Periodontitis | Keratoacanthoma | Autoimmune Interstitial Lung, Joint, And Kidney Disease | X-linked Sideroblastic Anemia | Creatine Deficiency Syndrome Due To AGAT Deficiency | DOCK8 Immunodeficiency Syndrome | Sotos Syndrome | Inflammatory Bowel Disease | Huntington's Disease-like 2 | Congenital Primary Aphakia | Early Infantile Epileptic Encephalopathy | Cancer, Skin | H Syndrome | IgA Nephropathy | Neuroectodermal Tumors, Primitive | Diastrophic Dysplasia | Papillorenal Syndrome | Onchocerciasis | Chromosome 17q21.31 Deletion Syndrome | Chondrodysplasia Punctata | Irritable Bowel Syndrome | Sleep Apnea, Central | Von Willebrand Disease | Prediabetes | Inborn Errors Of Metabolism | Osteochondrosis | ACTH-independent Macronodular Adrenal Hyperplasia | Spinocerebellar Ataxia Type 31 | Keratosis, Actinic | Alopecia | Vitelliform Macular Dystrophy | Amblyopia | Usher Syndrome Type III | Glycogen Storage Disease Type 5 | Epilepsy Of Infancy With Migrating Focal Seizures | Tibial Muscular Dystrophy | Myocardial Infarction | Sclerosteosis | Congenital Adrenal Hyperplasia | Pyoderma Gangrenosum | Diabetes | Aldosterone Deficiency | Neurocutaneous Syndromes | Scapuloperoneal Spinal Muscular Atrophy | Schuurs-Hoeijmakers Syndrome | Thin Basement Membrane Disease | Gigantism | Juvenile Hyaline Fibromatosis | McKusick Type Metaphyseal Chondrodysplasia | Infantile Liver Failure Syndrome 1 | CREST Syndrome | Hypertensive Retinopathy | Anodontia | Celiac Disease | Familial Isolated Hyperparathyroidism | Progressive Familial Intrahepatic Cholestasis Type 3 | Dysgerminoma | Chondrodysplasia Punctata 2, X-linked Dominant | Pathological Gambling | Congenital Afibrinogenemia | Mucormycosis | Cenani-Lenz Syndactyly Syndrome | Large Granular Lymphocytic Leukemia | Myoclonic Epilepsy With Ragged Red Fibers | Pneumococcal Meningitis | Papilledema | Spinal Muscular Atrophy Type 3 | Multiple Hamartoma Syndrome | Carney Triad | Personality Disorders | Aneurysm, Abdominal Aortic | Fanconi Anemia | Hepatopulmonary Syndrome | Trismus-pseudocamptodactyly Syndrome | Tardive Dyskinesia | Apraxia | Gastritis | Lymphedema-distichiasis Syndrome | Kearns-Sayre Syndrome | Dowling-Degos Disease | High Molecular Weight Kininogen Deficiency | Agnathia-Otocephaly Complex | Pleural Tuberculosis | Familial Male-limited Precocious Puberty | Spinal Cord Diseases | Encephalocele | Hereditary Pyropoikilocytosis | Otitis Externa | Diarrhea | Congenital Aniridia | Hypersomnia | Anuria | Osteogenesis Imperfecta Type III | Neurofibromatosis Type 2 | Rhabdoid Tumor | Arteriosclerosis | Camptocormia | Neurofibroma | Retinal Diseases | Spinocerebellar Ataxia Type 13 | Ileitis | Malignant Peripheral Nerve Sheath Tumor | Harlequin Ichthyosis | Dengue Shock Syndrome | Hereditary Sensory Neuropathy Type 1 | Thalassemia, Beta | Anovulation | Osteitis | Agranulocytosis | Cerebral Cavernous Malformations | Localized Scleroderma | Hereditary Spastic Paraplegia | Aneurysm, Thoracic Aortic | Motion Sickness | Von Hippel-Lindau Disease | Cholangiocarcinoma | Neurocutaneous Melanocytosis | Hoyeraal-Hreidarsson Syndrome | Muir-Torre Syndrome | Dominant Optic Atrophy | Angioedema, Hereditary | Lymphangioma | Adams-Oliver Syndrome | Dengue Hemorrhagic Fever | Jaundice, Obstructive | Heart Failure | Hepatitis E | Paraganglioma, Carotid Body | Keratoconus | Cancer, Kidney | Malaria, Cerebral | Peripheral T-cell Lymphoma | Biotinidase Deficiency | Chitayat Syndrome | Aldosterone Synthase Deficiency | Extramammary Paget's Disease | Fibrodysplasia Ossificans Progressiva | Enlarged Vestibular Aqueduct | Netherton Syndrome | Autonomic Neuropathy | Avian Influenza | VACTERL Association | Basal Cell Nevus Syndrome | Cutis Laxa | Saul-Wilson Syndrome | Neutropenia | Persistent Hyperplastic Primary Vitreous | Immunoproliferative Disorders | Glycogen Storage Disease Type 3 | Norrie Disease | X-linked Myotubular Myopathy | Short-chain Acyl-CoA Dehydrogenase Deficiency | HELLP Syndrome | Fatty Aldehyde Dehydrogenase Deficiency | Hereditary Folate Malabsorption | Renal Oncocytoma | Pseudohypoparathyroidism Type 1C | Infertility | Empyema | Combined Deficiency Of Factor V And Factor VIII | Epidermal Nevus Syndrome | Tay-Sachs Disease | Intermittent Claudication | Osteosarcoma | Nephrotic Syndrome | Chronic Neutrophilic Leukemia | Kleine-Levin Syndrome | Ehlers-Danlos Syndrome | Hemorrhoids | Tricho-hepato-enteric Syndrome | Lamellar Ichthyosis | Charcot-Marie-Tooth Disease | Proteus Syndrome | McLeod Syndrome | Cornelia De Lange Syndrome | Dermatitis | Esophageal Adenocarcinoma | Intermittent Explosive Disorder | Chondroma | Myositis, Focal | Pemphigoid | Hypoalbuminemia | Persistent Truncus Arteriosus | Astrocytoma, Anaplastic | GNE Myopathy | Congenital Nephrotic Syndrome | Hereditary Hemorrhagic Telangiectasia | Eosinophilia | Renpenning Syndrome | Epidermolytic Palmoplantar Keratoderma | Coenzyme Q10 Deficiency | Long QT Syndrome Type 3 | Erythrokeratodermia Variabilis | Primrose Syndrome | Bulimia Nervosa | Stargardt Disease | Marshall-Smith Syndrome | Congenital Generalized Lipodystrophy | Chronic Granulomatous Disease | Ichthyosis Bullosa Of Siemens | Asperger Syndrome | Angioedema, Acquired | Autosomal Recessive Bestrophinopathy | Congenital Bilateral Absence Of Vas Deferens | Inflammatory Linear Verrucous Epidermal Nevus | Cataract | Charcot-Marie-Tooth Disease, Type 2 | Leukemia | Bruck Syndrome | Leigh Syndrome | PHARC Syndrome | Acute Coronary Syndrome | Hyperostosis | Alopecia Totalis | Keratosis | Klippel-Feil Syndrome | Myoclonus-dystonia Syndrome | Subcortical Band Heterotopia | Malnutrition | Agoraphobia | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Stiff-man Syndrome | Dysthymia | Pierre Robin Syndrome | Congenital Lipoid Adrenal Hyperplasia | Multiple Sclerosis, Relapsing-remitting | Periodic Limb Movement Disorder | Whipple's Disease | Infantile Refsum Disease | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Retinitis | CHOPS Syndrome | Disseminated Superficial Actinic Porokeratosis | Occipital Neuralgia | Chronic Granulomatous Disease, X-linked | Pseudomyxoma Peritonei | Fuchs Heterochromic Iridocyclitis | Paroxysmal Kinesigenic Dyskinesia | Megaloblastic Anemia | Blepharo-cheilo-odontic Syndrome | Multicentric Carpotarsal Osteolysis Syndrome | Renal-hepatic-pancreatic Dysplasia | Hepatorenal Syndrome | GATA2 Deficiency | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | SAPHO Syndrome | Epidermolysis Bullosa Simplex, Localized | Transthyretin-related Amyloidosis | 3C Syndrome | Bethlem Myopathy | Schnyder Crystalline Corneal Dystrophy | Pulmonary Veno-occlusive Disease | Small Lymphocytic Lymphoma | Keratoconjunctivitis | Amenorrhea | Oculocutaneous Albinism Type 2 | Carcinoma, Merkel Cell | Dyskeratosis Congenita | Hemorrhagic Disorders | Mevalonate Kinase Deficiency | Insulinoma | Bronchiolitis | Prader-Willi Syndrome | Thyroiditis | Hemophilia | Amyloidosis | Osteonecrosis | Dermatomyositis | Oculocutaneous Albinism | HIBCH Deficiency | Papillon-Lefevre Syndrome | Bronchiectasis | Neurodevelopmental Disorders | Obesity, Morbid | Retinal Dystrophy | Lipid Storage Myopathy | DRESS Syndrome | Cryptorchidism | Hairy Cell Leukemia | Congenital Absence Of Vas Deferens | Patent Ductus Arteriosus | Wolff-Parkinson-White Syndrome | Globozoospermia | Osteogenesis Imperfecta | Richter's Syndrome | Waardenburg Syndrome Type 2 | Dysplastic Nevus | Hypervalinemia | Episodic Ataxia Type 1 | Epilepsy, Generalized | IMAGe Syndrome | Werner's Syndrome | Craniofacial Dysostosis | Vascular Calcification | Silicosis | Renal Failure | Heterotopic Ossification | Takenouchi-Kosaki Syndrome | CHARGE Syndrome | Cryoglobulinemia | Autoimmune Hemolytic Anemia | Borderline Personality Disorder | Cramp Fasciculation Syndrome | Cryptosporidiosis | Ganglioglioma | Chudley-McCullough Syndrome | Polydactyly | Macular Corneal Dystrophy | Tetraplegia | Sandhoff Disease | Succinic Semialdehyde Dehydrogenase Deficiency | Sweet Syndrome | Yellow Fever | Hypertension, Pulmonary | Myeloid Leukemia | Carcinoma, Small Cell | Influenza | Spinocerebellar Ataxia Type 8 | Charcot-Marie-Tooth Disease Type 2E | Hypertelorism
