Powered by AI technology, BDE-Bio combines massive literature, patent and comprehensive biological data to accurately screen and predict disease diagnosis and therapeutic targets / biomarkers. It can automatically generate target research reports with one click, making it an indispensable tool for pharmaceutical research and development.
BDE-Bio
TARGET PRECISE DISCOVERY
Product Introduction
BDE-Bio achieves precise screening and prediction of new targets by combining 24-hour continuous updates, massive literature texts, comprehensive biological databases, and large-scale multi-omics data, and can provide the basis and logic for target discovery.
1) Capture: 24-hour monitoring of Pubmed, 24 public databases (genecard, drugbank, pubchem, etc.), real-time inbound parsing.
2) Extraction: It can extract basic information about the target, protein structure, biological mechanism of the target, drug resistance of the target, disease correlation, etc.
3) Analysis: Summarize long content, generate reports with one click, recommend target points, etc.
Target Prediction
Predicting targets that can successfully enter the clinical trial stage and ensuring that lead compounds based on predicted targets can successfully break through the PCC stage within an estimated time frame.
Target-based Drug Prediction
Predicting the difficulty level of target-based drug development provides a basis for assessing the value of target exploration.
Disease-Related Target Prediction
Predicting key targets for specific diseases and provide a basis for drug development for rare diseases and difficult and complicated diseases.
Common Targets and Diseases
Targets
ABCB1 | ABCG2 | ACE2 | AHR | AKT1 | ALK | AR | ATM | BAX | BCL2 | BCL2L1 | BECN1 | BRAF | BRCA1 | CAMP | CASP3 | CASP9 | CCL5 | CCND1 | CD274 | CD4 | CD8A | CDH1 | CDKN1A | CDKN2A | CREB1 | CXCL8 | CXCR4 | DNMT1 | EGF | EGFR | EP300 | ERBB2 | EREG | ESR1 | EZH2 | FN1 | FOXO3 | HDAC9 | HGF | HMGB1 | HSP90AA1 | HSPA4 | HSPA5 | IDO1 | IFNA1 | IGF1 | IGF1R | IL17A | IL6 | INS | JUN | KRAS | MAPK1 | MAPK14 | MAPK3 | MAPK8 | MAPT | MCL1 | MDM2 | MET | MMP9 | MTOR | MYC | NFE2L2 | NLRP3 | NOTCH1 | PARP1 | PCNA | PDCD1 | PLK1 | PRKAA1 | PRKAA2 | PTEN | PTGS2 | PTK2 | RELA | SIRT1 | SLTM | SMAD4 | SOD1 | SQSTM1 | SRC | STAT1 | STAT3 | STAT5A | TAK1 | TERT | TLR4 | TNF | TP53 | TXN | VEGFA | YAP1
Diseases
Spondylo-ocular Syndrome | Weill-Marchesani Syndrome | Citrullinemia | Paget's Disease Of The Breast | Dystonia-parkinsonism, X-linked | Schwannomatosis | Hypotension, Orthostatic | Congenital Bilateral Absence Of Vas Deferens | Muscular Dystrophy | Large Granular Lymphocytic Leukemia | Crouzon Syndrome With Acanthosis Nigricans | Cancer, Bladder | Porokeratosis | Hereditary Multiple Exostoses | Pre-eclampsia | Chorea | Cri-du-chat Syndrome | Niemann-Pick Disease, Type A | Pseudohypoaldosteronism | Pemphigus Foliaceus | Nutrition Disorders | Multifocal Motor Neuropathy | Eosinophilia | Asphyxia Neonatorum | Hemolytic Uremic Syndrome, Atypical | Cellulitis | Polyradiculopathy | Membranous Nephropathy | Cholangitis | Usher Syndrome Type I | Hemophagocytic Lymphohistiocytosis | Pulmonary Veno-occlusive Disease | Hypophosphatasia | Nijmegen Breakage Syndrome | Chediak-Higashi Syndrome | Congenital Tufting Enteropathy | Inflammatory Bowel Disease | Major Depression | Dysgerminoma | Glycogen Storage Disease Type 4 | Cancer, Brain | Lymphangioleiomyomatosis | Parkinsonism | Acute Anterior Uveitis | 17-beta-hydroxysteroid Dehydrogenase X Deficiency | Hyperinsulinemic Hypoglycemia | Sarcoidosis | Multiple Sclerosis, Relapsing-remitting | Alopecia Totalis | Gastric Atrophy | Polymyalgia Rheumatica | Blastomycosis | Multiple Epiphyseal Dysplasia | Carcinoma, Signet Ring Cell | Persistent Fetal Circulation | Hepatitis | Discoid Lupus Erythematosus | Reflex Epilepsy | Palsy, Cerebral | Pure Red Cell Aplasia | Dupuytren Disease | Microphthalmia | Cenani-Lenz Syndactyly Syndrome | Central Retinal Artery Occlusion | Fabry's Disease | Colon Adenoma | Exocrine Pancreatic Insufficiency | Carcinoma, Squamous Cell | Richter's Syndrome | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Spinocerebellar Ataxia Type 27 | Ophthalmia, Sympathetic | Bullous Pemphigoid | Onchocerciasis | Pontocerebellar Hypoplasia | Chronic Granulomatous Disease, X-linked | 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Treacher Collins Syndrome | Dysmorphophobia | Orthostatic Intolerance | GM2-gangliosidosis AB Variant | Biotinidase Deficiency | Epidermolytic Ichthyosis, Annular | Hypercholesterolemia | Primary Biliary Cholangitis | Menkes Disease | Nemaline Myopathy 10 | Chorea-acanthocytosis | Seizures | Graft-versus-host Disease | Pain | Leukoencephalopathy, Progressive Multifocal | Hypodontia | Kaposi Sarcoma | Seizures-scoliosis-macrocephaly Syndrome | Angioedema | Kernicterus | Meningitis | McLeod Syndrome | Carbohydrate Metabolism Disorders | Donnai-Barrow Syndrome | Creutzfeldt-Jakob Disease | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Fuchs Heterochromic Iridocyclitis | 6-pyruvoyl-tetrahydropterin Synthase Deficiency | Pernicious Anemia | Cutis Laxa | Charcot-Marie-Tooth Disease Type 3 | Retinal Diseases | Cancer, Prostate | Fanconi Anemia | Cholestasis | SAPHO Syndrome | Odonto-onycho-dermal Dysplasia | Plasmacytoma | Mitochondrial Encephalomyopathy | Cardiac Sarcoidosis | Erythropoietic Protoporphyria | Melanoma, Uveal | Early Infantile Epileptic Encephalopathy | Neurodegeneration With Brain Iron Accumulation | Glutaric Aciduria Type 2 | Trichuriasis | Neurofibromatosis | Isobutyryl-CoA Dehydrogenase Deficiency | Disseminated Intravascular Coagulation | Localized Scleroderma | Multiple Sclerosis, Primary Progressive | Congenital Nystagmus | Autosomal Recessive Spastic Paraplegia Type 35 | Becker Muscular Dystrophy | Charcot-Marie-Tooth Disease, Type 2C | Atrial Septal Defect | Fascioliasis | Jaundice, Obstructive | Spinocerebellar Ataxia Type 20 | Congenital Torticollis | Acromesomelic Dysplasia | Martsolf Syndrome | Seasonal Mood Disorder | Beare-Stevenson Syndrome | Colitis, Collagenous | Priapism | Neovascular Glaucoma | Cryptosporidiosis | Usher Syndrome Type III | Non-Langerhans Cell Histiocytosis | Vertebrobasilar Insufficiency | Adrenoleukodystrophy, X-linked | Hoyeraal-Hreidarsson Syndrome | Rubinstein-Taybi Syndrome | Canavan Disease | Congenital Stromal Corneal Dystrophy | Granular Corneal Dystrophy | Pseudohypoparathyroidism Type 1C | Sialidosis | Thrombosis | Dystrophy, Cone-rod | Joubert Syndrome | X-linked Sideroblastic Anemia | Mixed Connective Tissue Disease | Meleda Disease | Niemann-Pick Disease, Type B | Dyskeratosis Congenita | Alkaptonuria | Carotid Artery Disease | Blepharoconjunctivitis | Brachial Plexus Neuropathy | Amblyopia | Chronic Mucocutaneous Candidiasis | Angioedema, Hereditary | Primary Hyperoxaluria Type 3 | Pontocerebellar Hypoplasia Type 2 | Familial Hypertrophic Cardiomyopathy | Proctitis | GNE Myopathy | Cramp Fasciculation Syndrome | Osteogenesis Imperfecta Type IV | Malnutrition | Sensorineural Hearing Loss | Osteosclerosis | Chronic Myelomonocytic Leukemia | Tietze Syndrome | Triphalangeal Thumb-polysyndactyly Syndrome | Acrodermatitis | Succinic Semialdehyde Dehydrogenase Deficiency | Glycogen Storage Disease | Lyme Disease | Zygomycosis | Paroxysmal Nocturnal Hemoglobinuria | Allan-Herndon-Dudley Syndrome | Pulmonary Alveolar Proteinosis | Pitt-Hopkins Syndrome | Aromatic L-amino Acid Decarboxylase Deficiency | Choriocarcinoma | Multiple Sclerosis | Cystitis | Pierpont Syndrome | Pseudohermaphroditism | Neurocutaneous Melanocytosis | Roberts Syndrome | Eiken Syndrome | Adenoma, Villous | Myofibrillar Myopathy | Lymphomatoid Granulomatosis | Nicotine Addiction | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Spinocerebellar Ataxia Type 40 | Familial Partial Lipodystrophy | Mountain Sickness | Multiple Myeloma | Polycythemia Vera | Hypersensitivity Pneumonitis | Epidermolytic Hyperkeratosis | Lymphedema | Restless Legs Syndrome | Dengue Hemorrhagic Fever | Spasticity | Astrocytoma | Mitochondrial DNA Depletion Syndrome, Myopathic Form | Ischemia | Ovarian Hyperstimulation Syndrome | Dermatofibrosarcoma | Filariasis | Galloway-Mowat Syndrome | Intestinal Pseudo-obstruction | Chronic Leukemia | Dwarfism | Spondylosis | Preaxial Polydactyly | Lung Diseases | Familial Dysautonomia | Goiter, Nodular | Smoldering Myeloma | Rett Syndrome | Strabismus | Zellweger Syndrome | Asplenia | Chylomicron Retention Disease | Necrobiosis Lipoidica | Leprosy | Charcot-Marie-Tooth Disease Axonal Type 2N | Liddle Syndrome | Spinocerebellar Ataxia Type 1 | Stomatitis | Retinitis | Amenorrhea | Sulfite Oxidase Deficiency | Hereditary Mixed Polyposis Syndrome | Corneal Neovascularization | Spinal Muscular Atrophy Type 3 | CHOPS Syndrome | Alstrom Syndrome | Osmotic Demyelination Syndrome | Obesity, Morbid | Malonyl-CoA Decarboxylase Deficiency | Lattice Corneal Dystrophy Type 1 | Prolactinoma | Meconium Ileus | Dystonia Musculorum Deformans | Jalili Syndrome | Clouston Hidrotic Ectodermal Dysplasia | Myhre Syndrome | Thin Basement Membrane Disease | Papilloma | Hepatitis, Chronic | Macrodactyly | Ovarian Sex Cord-stromal Tumor | Osteogenesis Imperfecta | Primrose Syndrome | Acne Vulgaris | Medulloblastoma | Retinal Detachment | Trachoma | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | Neuroma | Sturge-Weber Syndrome | Hyperacusis | Hypersensitivity | Peters-plus Syndrome | Adams-Oliver Syndrome | Hypospadias | Giant Cell Arteritis | Diabetes Type 1 | Progressive Familial Intrahepatic Cholestasis Type 3 | Feingold Syndrome | Compartment Syndrome | Thrombocytopenia | Alpha-1 Antitrypsin Deficiency | Brachydactyly | Diffuse Palmoplantar Keratoderma | Histoplasmosis | Multicentric Carpotarsal Osteolysis Syndrome | Dementia | Fowler's Syndrome | Aicardi-Goutieres Syndrome | Intestinal Hypomagnesemia 1 | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Megalencephaly | Panuveitis | Polycystic Kidney, Autosomal Recessive | Guillain-Barre Syndrome | Methemoglobinemia | Frontometaphyseal Dysplasia | Aarskog-Scott Syndrome | Anorchia | Autosomal Recessive Congenital Ichthyosis | Nephrotic Syndrome | Cornelia De Lange Syndrome | Corneal Dystrophy And Perceptive Deafness | Myotonia | Pyruvate Dehydrogenase Deficiency | Metabolic Syndrome | Hereditary Neuropathy With Liability To Pressure Palsies | Bethlem Myopathy | Vitelliform Macular Dystrophy | Periventricular Leukomalacia | Asthma, Exercise-induced | Axenfeld-Rieger Syndrome | Chronic Idiopathic Myelofibrosis | Congenital Afibrinogenemia | Neuronal Ceroid Lipofuscinosis | Papillorenal Syndrome | Diabetic Macular Edema | Hyperparathyroidism, Secondary | Macular Corneal Dystrophy | Congenital Heart Defects | Borjeson-Forssman-Lehmann Syndrome | Dystonia | Harlequin Ichthyosis | Albinism | Meier-Gorlin Syndrome | Osteosarcoma | Antley-Bixler Syndrome | Trimethylaminuria | DiGeorge Syndrome | Photosensitivity | Pseudohypoparathyroidism Type 1A | Synovitis | Dyslexia | Juvenile Myoclonic Epilepsy | Congenital Aniridia | Congenital Mirror Movements | Renal Failure | Encephalitis, Tick-borne | Botulism | Hypervalinemia | Neurofibrosarcoma | Phenylketonuria II | Saethre-Chotzen Syndrome | Optic Neuropathy, Anterior Ischemic | Optic Neuropathy | Omenn Syndrome | Hepatitis, Alcoholic | Sleep Apnea, Obstructive | Limb Girdle Muscular Dystrophy | Polydactyly | Focal Facial Dermal Dysplasia | Tyrosinemia Type 2 | Birt-Hogg-Dube Syndrome | Hypobetalipoproteinemias | Diabetes | Arthropathy | Raine Syndrome | Sensory Neuropathy | Panniculitis | Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis | Cluster Headache | Progressive Familial Intrahepatic Cholestasis | Tangier Disease | Urethritis | Subacute Sclerosing Panencephalitis | Sorsby Fundus Dystrophy | Chronic Thromboembolic Pulmonary Hypertension | Occipital Neuralgia | Retinal Telangiectasia | Sotos Syndrome | Eating Disorder | Hyperlipidemia | Sarcoma, Ewing | Atopy | Hemolytic Anemia | Combined Deficiency Of Factor V And Factor VIII | 3-hydroxy-3-methylglutaryl-CoA Synthase Deficiency | Ataxia-hypogonadism-choroidal Dystrophy Syndrome | Familial Pheochromocytoma-paraganglioma | Angelman Syndrome | Tenosynovial Giant Cell Tumor | Celiac Disease | Withdrawal Syndrome | Carcinoma, Merkel Cell | LMNA-related Congenital Muscular Dystrophy | Vascular Cognitive Impairment | Myocarditis | Congenital Stationary Night Blindness | Hemoglobinopathies | Vitreoretinopathy, Proliferative | Gangliosidosis, GM1 | Congenital Myasthenic Syndrome | Polycythemia
