Disease

Aneurysm, Thoracic Aortic

About the Disease
Aortic Aneurysm, Familial Thoracic 1, also known as thoracic aortic aneurysm, is related to aortic aneurysm, familial thoracic 6 and aortic aneurysm, familial thoracic 10. An important gene associated with Aortic Aneurysm, Familial Thoracic 1 is MYH11 (Myosin Heavy Chain 11), and among its related pathways/superpathways are ERK Signaling and Signal Transduction. The drugs Acetazolamide and Iodine have been mentioned in the context of this disorder. Affiliated tissues include thoracic aorta, smooth muscle and heart, and related phenotypes are cutis marmorata and mucoid extracellular matrix accumulation

Common Targets
FBN1 | MMP17 | COL1A1 | G4851 | COL4A1 | EFEMP2 | MYLK2 | LOX | MYH11 | TGFBR1 | SMAD6 | FBN2 | Reverse transcriptase (Telomerase) | COL5A1 | ATP6V0A2 | FLNA | COL1A2 | EMILIN1 | MMP2 | BGN | COL5A2 | SLC2A10 | LRP1 | TGFB2 | ZFPM2 | G7015 | ABCC6 | MYLK | LTBP3 | ZNF469 | SMAD3 | B3GALT6 | MFAP5 | HBEGF | TCF7L2 | TGFBR2 | PRKG1 | IPO8 | MAT2A | COL3A1 | ACTA2 | ADAMTSL2 | SKI

疾病靶点研报
Aneurysm, thoracic aortic

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