Disease

Fanconi Anemia

About the Disease
Diamond-Blackfan Anemia, also known as congenital pure red cell aplasia, is related to diamond-blackfan anemia 1 and diamond-blackfan anemia 10. An important gene associated with Diamond-Blackfan Anemia is RPS19 (Ribosomal Protein S19), and among its related pathways/superpathways are Metabolism of proteins and Metabolism. The drugs Deferasirox and Liver Extracts have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, bone and myeloid, and related phenotypes are pure red cell aplasia and elevated red cell adenosine deaminase level

Common Targets
SLX4 | UBE2T | SCN5A | FANCD2 | FANCE | G1956 | XRCC2 | FAN1 | MAD2L2 | DNA2 | G7124 | AMP-activated protein kinase (AMPK) | RHO | ALDH2 | BRCA2 | FANCL | COMT | MAOA | KIT | G23411 | G7852 | MRE11 | FANCI | FANCB | XDH | STS | PTPN1 | MPL | FANCF | RAD51 | USP8 | GTPase (nonspecified subtype) | G3630 | ERCC4 | FANCG | PALB2 | RAD51C | FANCA | G196 | CXCR2 | BRIP1 | PDE5A | GAA | G672 | CD47 | RFWD3 | STXBP2 | FANCC | FANCM | Voltage-Gated Calcium Channel alpha-2/delta (nonspecified subtype)

疾病靶点研报
Fanconi Anemia

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