Disease

Malignant Thymoma

About the Disease
Thymic Carcinoma, also known as malignant thymoma, is related to lymphoepithelioma-like thymic carcinoma and thymus adenocarcinoma. An important gene associated with Thymic Carcinoma is KIT (KIT Proto-Oncogene, Receptor Tyrosine Kinase), and among its related pathways/superpathways are Cytoskeletal Signaling and Hippo-Merlin signaling dysregulation. The drugs Paclitaxel and Pembrolizumab have been mentioned in the context of this disorder. Affiliated tissues include thymus, thyroid and bone marrow, and related phenotypes are mediastinal lymphadenopathy and neoplasm of the thymus

Common Targets
PDGFRB | DNMT3A | Uncharacterized LOC101928822, transcript variant X1 | GH1 | POLE | GTF2I | Somatostatin receptor (nonspecified subtype) | PIK3CA | FLT4 | FGFR1 | FLT1 | SPTA1 | KDR | DNMT3B | SMARCA4 | RICTOR | RET | SST | SMAD2 | BCOR | PDGFRA | MGMT | WT1 | HIF1A-AS2 | VCP | TNFRSF4 | G472 | TOP2A | ARID1A | KIT | G7157 | PRKN | FGFR2 | TNFRSF9 | HIF1A | KDM5A | G1029 | KDM6A | NRAS | EPHB1 | ERCC1 | NF2 | TYK2

疾病靶点研报
Malignant Thymoma

Note: If you'd like to get a target analysis report for Malignant Thymoma, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Malignant Thymoma at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Fetal Akinesia Deformation Sequence | Thin Basement Membrane Disease | Epidermolytic Ichthyosis, Annular | Analgesia | Camptocormia | Ganglioneuroma | Osteopathia Striata With Cranial Sclerosis | Osteitis | Central Pain Syndrome | Thrombosis | Parvovirus B19 Infection | Atherosclerosis | Bloom Syndrome | Bernard-Soulier Syndrome | Familial Glucocorticoid Deficiency | NGLY1 Deficiency | Chronic Idiopathic Myelofibrosis | Macular Corneal Dystrophy Type 1 | Pelvic Inflammatory Disease | Geleophysic Dysplasia | Neurotoxicity | Long-chain 3-hydroxyacyl-coenzyme A Dehydrogenase Deficiency | Osteomyelitis | Antiphospholipid Syndrome | Cavitary Optic Disc Anomalies | Sleep Apnea | Hypertension, Renal | Lymphoproliferative Disease, X-linked | Myasthenia Gravis | VACTERL/VATER Association | Familial Partial Lipodystrophy | Acute Tubular Necrosis | Spitzoid Melanoma | Schizencephaly | Bladder Exstrophy | Schindler Disease | Carcinoma In Situ | Primary Erythromelalgia | Overactive Bladder | Lymphoma, Primary Cutaneous Anaplastic Large Cell | Opisthorchiasis | Seizures | Osteochondrosis | Krabbe Disease | Waardenburg Syndrome | H Syndrome | Adams-Oliver Syndrome | Progressive External Ophthalmoplegia | Sarcosinemia | Brachial Plexus Neuropathy | Hemorrhagic Disorders | Peritonitis | Pain | Sandhoff Disease | Primary Lateral Sclerosis | Benign Familial Infantile Seizures | Periodontitis | X-linked Charcot-Marie-Tooth Disease | Tietze Syndrome | Mandibuloacral Dysplasia With Type A Lipodystrophy | Meesmann Corneal Dystrophy | Chitayat Syndrome | Urofacial Syndrome | Angioedema, Acquired | Erythema Multiforme | Wiedemann-Steiner Syndrome | Chronic Inflammatory Demyelinating Polyneuropathy | Amyotrophic Lateral Sclerosis-parkinsonism-dementia Complex | Galactosialidosis | Galactosemia | Van Der Knaap Disease | Postpoliomyelitis Syndrome | Duchenne Muscular Dystrophy | Angiodysplasia | Mumps | Leukoplakia, Oral | Behcet's Disease | Li-Fraumeni Syndrome | Cutaneous Angiosarcoma | Depression | Loeys-Dietz Syndrome | Carbamoyl Phosphate Synthetase I Deficiency | Angina Pectoris | Hereditary Elliptocytosis | Coloboma | Autosomal Recessive Congenital Ichthyosis | Leishmaniasis, Cutaneous | Osteogenesis Imperfecta | Fowler's Syndrome | Lymphoma | NDH Syndrome | Hypocalcemia | Microvillus Inclusion Disease | Carney Triad | Tyrosinemia Type 2 | Neurocysticercosis | Sarcoma, Endometrial Stromal | Pseudohermaphroditism | Sickle Cell Anemia | Familial Hemiplegic Migraine | Iron Overload | Allan-Herndon-Dudley Syndrome | PASLI Disease | Short-chain Acyl-CoA Dehydrogenase Deficiency | Gingivitis | Echinococcosis | Basal Ganglia Disease | Endocarditis | Nephrocalcinosis | Epidermolysis Bullosa | Familial Advanced Sleep Phase Syndrome | Early Infantile Epileptic Encephalopathy 4 | Nemaline Myopathy | Renal Medullary Carcinoma | Chiari Malformation Type I | Dermatitis | Glioblastoma | Hypervalinemia | DICER1 Syndrome | Ichthyosis Hystrix, Curth-Macklin Type | GATA2 Deficiency | Androgen Insensitivity | Hemochromatosis Type 1 | Chorea | Vitamin B12 Deficiency | Lymphedema-distichiasis Syndrome | Immunoproliferative Disorders | Granuloma Annulare | Motion Sickness | Extramammary Paget's Disease | Hairy Cell Leukemia | Congenital Stromal Corneal Dystrophy | Glaucoma, Congenital | McKusick Type Metaphyseal Chondrodysplasia | Congenital Adrenal Hyperplasia 1 | Zollinger-Ellison Syndrome | Lyme Disease | Hyperparathyroidism, Primary | Seborrheic Dermatitis | Autoimmune Polyendocrine Syndrome | Keratopathy | MELAS Syndrome | Acquired Partial Lipodystrophy | Roberts Syndrome | Blepharospasm | Arteriosclerosis | Neurofibromatosis Type 1 | Renal Failure | Craniofacial Dysostosis | Waardenburg Syndrome Type 4 | Mabry Syndrome | GM2-gangliosidosis AB Variant | Hemimegalencephaly | Dubin-Johnson Syndrome | Autosomal Recessive Spastic Paraplegia Type 54 | Dental Caries | Diastrophic Dysplasia | Craniosynostosis | Takotsubo Cardiomyopathy | Carcinoid Syndrome | Neuromyotonia | Urticaria | Muir-Torre Syndrome | Ataxia-ocular Apraxia 2 | Deafness, Dystonia, And Cerebral Hypomyelination | Jawad Syndrome | Carbonic Anhydrase VA Deficiency | Acute Motor Axonal Neuropathy | Acromegaly | Coffin-Siris Syndrome | Primary Ovarian Insufficiency | Jacobsen Syndrome | 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Dysmorphophobia | Hyperacusis | Monilethrix | Amebiasis | Thyroid Dysgenesis | Colitis, Microscopic | Lipoma | Sorsby Fundus Dystrophy | Epilepsy, Generalized | Hypereosinophilic Syndrome | Dysequilibrium Syndrome | Thyroid Hormone Resistance | Blau Syndrome | Heroin Dependence | Polydactyly | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Lymphedema | Neuromuscular Disorders | Spinocerebellar Ataxia Type 8 | Frontometaphyseal Dysplasia | Splenomegaly | Spinal Muscular Atrophy | Schamberg Disease | Gallstones | Synovitis | Osteogenesis Imperfecta Type V | Xeroderma Pigmentosum Variant Type | Lymphangioma | Pantothenate Kinase-associated Neurodegeneration | Amish Infantile Epilepsy Syndrome | Azoospermia | Venous Insufficiency | Diabetes Insipidus | Periventricular Leukomalacia | Inflammatory Myofibroblastic Tumor | Pulmonary Capillary Hemangiomatosis | Best Macular Dystrophy | Poirier-Bienvenu Neurodevelopmental Syndrome | Anorectal Malformations | Prolactinoma | Craniolenticulosutural Dysplasia | Choroideremia | Dyggve-Melchior-Clausen Disease | Anti-glomerular Basement Membrane Disease | Poretti-Boltshauser Syndrome | Von Willebrand Disease | Treacher Collins Syndrome | Pouchitis | Thrombasthenia | Cholera | Dysthymia | Neovascular Glaucoma | Carpenter Syndrome | Paraganglioma | Kabuki Syndrome 2 | Niemann-Pick Disease, Type A | Hepatoblastoma | Cystitis | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Autism | Tumoral Calcinosis | VACTERL Association | Cerebrovascular Disorders | Osteoarthritis | Fundus Albipunctatus | Vici Syndrome | Oculocutaneous Albinism Type 2 | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 1 | Systemic Mastocytosis | Nephroblastoma | Barrett Esophagus | Presbycusis | 3-methylglutaconic Aciduria Type I | Crigler-Najjar Syndrome | Arthritis, Reactive | Phenylketonuria II | IgA Deficiency | Porphyria | Hereditary Neuropathy With Liability To Pressure Palsies | L-2-Hydroxyglutaric Aciduria | Cancer, Brain | Alpha-mannosidosis | Dysplastic Nevus | Osteoglophonic Dysplasia | Blastoma, Pleuropulmonary | Cancer, Bladder | Hartsfield Syndrome | Cystinosis | Avellino Corneal Dystrophy | Non-Hodgkin Lymphoma | Cardiomyopathy, Hypertrophic | Bursitis | Craniofrontonasal Syndrome | Vasculitis | Coronary Heart Disease | Charcot-Marie-Tooth Disease, Type 2C | Chanarin-Dorfman Syndrome | Pulmonary Tuberculosis | Pneumoconiosis | Sensory Neuropathy | Spondylolisthesis | Odonto-onycho-dermal Dysplasia | Myelitis | Uveitis, Anterior | T-cell Prolymphocytic Leukemia | Auriculocondylar Syndrome | Stuve-Wiedemann Syndrome | Pituitary Disorders | Autoimmune Autonomic Ganglionopathy | IMAGe Syndrome | Sporadic Inclusion Body Myositis | Sarcoma, Alveolar Soft Part | Angiosarcoma | Esthesioneuroblastoma | Cutaneous T-cell Lymphoma | Encephalopathy | Cataplexy | Hypospadias | Rhizomelic Chondrodysplasia Punctata | Usher Syndrome Type III | REM Sleep Behavior Disorder | Alopecia Areata | Blepharophimosis Syndrome | Hyperprolactinemia | Exfoliative Dermatitis | Conjunctivitis | Budd-Chiari Syndrome | Trigonocephaly | Distal Myopathy | Noonan Syndrome | Retinitis Pigmentosa | Raynaud Phenomenon | Multicystic Renal Dysplasia | Schizoaffective Disorder | Hyperandrogenemia | Christianson Syndrome | Phosphoglycerate Dehydrogenase Deficiency | Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia | Glioblastoma Multiforme | AIDS Dementia Complex | Crimean-Congo Hemorrhagic Fever | Exocrine Pancreatic Insufficiency | Colitis | Moyamoya Disease | Atopy | Spitz Nevus | Hepatitis, Chronic | Dermatofibrosarcoma | Lentigo | Idiopathic Pulmonary Fibrosis | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Dystonia Musculorum Deformans | Stomatitis | Erythematotelangiectatic Rosacea | Charcot-Marie-Tooth Disease Type 4E | Pancytopenia | Angelman Syndrome | Familial Dysautonomia | Hyperferritinemia-cataract Syndrome | Adenoma, Pituitary | Thromboembolism | Down Syndrome | Diabetic Macular Edema | Macular Degeneration | Amelogenesis Imperfecta | Yellow Fever | Hemangioendothelioma | Cryoglobulinemia | Tricho-hepato-enteric Syndrome | Waardenburg Syndrome Type 2A | Cholestasis | Acute Chest Syndrome | Kleine-Levin Syndrome | Kallmann Syndrome | Cutaneous Lupus Erythematosus | Growth Hormone Excess | Adenoma, Pleomorphic | Atopic Dermatitis | Familial Hypobetalipoproteinemia | Myoclonus-dystonia Syndrome | Sarcoidosis, Pulmonary | Spinal Muscular Atrophy Type 2 | Autosomal Recessive Bestrophinopathy | Lactose Intolerance | Rubeosis Iridis | Distal Myopathy 2 | Adult Polyglucosan Body Disease | Mevalonate Kinase Deficiency | Sweet Syndrome | Arteriovenous Malformations | Pregnancy, Ectopic | Encephalocele | Dengue Shock Syndrome | Osteogenesis Imperfecta Type II | Neurodermatitis | Hashimoto Thyroiditis | Hidradenitis Suppurativa | Batten Disease | Lattice Corneal Dystrophy Type 1 | Autonomic Nervous System Disorders | Schuurs-Hoeijmakers Syndrome | Ulcerative Colitis | Hypotonia-cystinuria Syndrome | Hemolytic Uremic Syndrome | Dementia | Milk Allergy | Bainbridge-Ropers Syndrome | Fuchs Dystrophy | Tetraplegia | Acrocallosal Syndrome | Polycystic Kidney, Autosomal Recessive | Granular Corneal Dystrophy Type 1 | Zimmermann-Laband Syndrome | ACTH-independent Macronodular Adrenal Hyperplasia | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | Retinal Vasculitis | Hyperlipidemia, Familial Combined | Bronchitis | Hereditary Hemorrhagic Telangiectasia Type 2 | Subacute Sclerosing Panencephalitis | Absence Epilepsy | Spinocerebellar Ataxia Type 14 | Intestinal Hypomagnesemia 1 | Thalassemia | Polycystic Kidney, Autosomal Dominant | Chylomicron Retention Disease | Still Disease